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Detailed seismic zoning of the East kazakhstan region in the Republic of kazakhstan

Geodesy and Geodynamics 2024年第2期15卷 156-165页

作者： Natalya V.Silacheva N.P.Stepanenko o.k.kurilova A.D.kudabayeva A.T.Danabayeva Institute of Seismology Ministry of Emergency SituationsAlmaty 050060Kazakhstan

kazakhstan is currently drafting new construction regulations that comply with the major provisions of the *** regulations are created on the basis of seismic zoning maps of various degrees of detail,developed by our Institute of Seismology using a new methodological approach for *** article is about creating the first normative map of the Detailed Seismic Zoning on a probabilistic foundation for the Republic of kazakhstan’s East kazakhstan *** carried out the probabilistic assessment of seismic hazard using a methodology consistent with the main provisions of Eurocode 8and updated compared with that used in developing maps of kazakhstan’s General Seismic Zoning and seismic microzoning of *** most thorough and current data accessible for the area under consideration were combined with contemporary analytical *** have been done to not only the databases being used but also the way seismic sources were shown,including active faults *** a scale of 1:1000000,precise seismic zoning maps of the East kazakhstan region were created for two probabilities of exceedance:10%and 2%in 50 years in terms of peak ground accelerations and macroseismic *** obtained seismic hazard distribution is generally consistent with the General Seismic Zoning of kazakhstan’s previous ***,because active faults were included and a thoroughly revised catalog was used,there are more pronounced zones of increased danger along the fault in the western part of the *** the west of the territory,acceleration values also increased due to a more accurate consideration of seismotectonic *** maps are the basis for developing new state building regulations of the Republic of kazakhstan.

关键词： Probabilistic seismic hazard assessment Detailed seismic zoning Peak ground acceleration Microseismical intensity

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Multilayered organic semiconductors for high performance optoelectronic stimulation of cells

引用

Nano Research 2023年第4期16卷 5809-5816页

作者： Aleksandr Markov Alexander Gerasimenko Annie-kermen Boromangnaeva Sofia Shashova Elena Iusupovskaia Ulyana kurilova Vita Nikitina Irina Suetina Marina Mezentseva Mikhail Savelyev Peter Timashev Dmitry Telyshev Xing-Jie Liang Institute for Bionic Technologies and Engineering I.M.Sechenov First Moscow State Medical UniversityMoscow 119991Russia Institute of Biomedical Systems National Research University of Electronic TechnologyZelenogradMoscow 124498Russia Chemistry Department Lomonosov Moscow State UniversityLeninskie Gory1/3Moscow 119991Russia Ivanovsky Institute of Virology N.F.Gamaleya National Center of Epidemiology and MicrobiologyMoscow 123098Russia World-Class Research Center“Digital Biodesign and Personalized Healthcare” I.M.Sechenov First Moscow State Medical UniversityMoscow 119991Russia Laboratory of Clinical Smart Nanotechnologies I.M.Sechenov First Moscow State Medical UniversityMoscow 119991Russia Institute for Regenerative Medicine I.M.Sechenov First Moscow State Medical UniversityMoscow 119991Russia CAS key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in NanoscienceNational Center for Nanoscience and Technology of ChinaBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

The efficiency of devices for bioelectronic applications,including cell and tissue stimulation,is heavily dependent on the scale and the performance *** miniaturization of stimulation electrodes,achieving a sufficiently high current pulse to elicit action potentials becomes an *** we report on our approach of vertically stacking organic p-n junctions to create highlyefficient multilayered organic semiconductor(MoS)photostimulation device.A tandem arrangement substantially increases the photovoltage and charge density without sacrificing lateral area,while not exceeding 200-500 nm of *** devices generate 4 times higher voltages and at least double the charge densities over single p-n junction devices,which allow using lower light intensities for *** devices show an outstanding stability in the electrolyte that is extremely important for forthcoming in vivo ***,we have validated MoS devices performance by photostimulating fibroblasts and neuroblasts,and found that using tandem devices leads to more effective action potential *** a result,we obtained up to 4 times enhanced effect in cell growth density using 3 p-n layered *** results corroborate the conclusion that MoS technology not only can achieve parity with state-of-the-art silicon devices,but also can exceed them in miniaturization and performance for biomedical applications.

关键词： bioelectronics organic semiconductors wireless stimulation fibroblasts neuroblastoma cells

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