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Arrhythmic syncope: From diagnosis to management

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World Journal of Cardiology 2023年第4期15卷 119-141页

作者： Jaume Francisco Pascual Pablo Jordan Marchite Jesús Rodríguez Silva nuria Rivas Gándara Unitat d’Arritmies Servei de Cardiologia VHIR Hospital Universitari Vall d’HebronBarcelona 08035Spain Grup de Recerca Cardiovascular Vall d’Hebron Institut de RecercaBarcelona 08035Spain CIBER de Enfermedades Cardiovasculares Instituto de Salud Carlos ⅢMadrid 28029Spain Departament de Medicina Universitat Autònoma de BarcelonaBellaterra 08193Spain

Syncope is a concerning symptom that affects a large proportion of *** can be related to a heterogeneous group of pathologies ranging from trivial causes to diseases with a high risk of sudden ***,benign causes are the most frequent,and identifying high-risk patients with potentially severe etiologies is crucial to establish an accurate diagnosis,initiate effective therapy,and alter the *** term cardiac syncope refers to those episodes where the cause of the cerebral hypoperfusion is directly related to a cardiac disorder,while arrhythmic syncope is cardiac syncope specifically due to rhythm ***,arrhythmias are the most common cause of cardiac *** bradyarrhythmia and tachyarrhythmia can cause a sudden decrease in cardiac output and produce *** this review,we summarized the main guidelines in the management of patients with syncope of presumed arrhythmic ***,we presented a thorough approach to syncope work-up through different tests depending on the clinical characteristics of the patients,risk stratification,and the management of syncope in different scenarios such as structural heart disease and channelopathies.

关键词： Syncope Arrhythmia Electrophysiological study Loop recorder Myocardiopathy Atrioventricular conduction block

基体材料力学性能对316L不锈钢颗粒沉积行为的影响

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金属学报 2016年第12期52卷 1610-1618页

作者：马广璐崔新宇沈艳芳 nuria CINCA Josep M.GUILEMANY 熊天英中国科学院金属研究所沈阳110016 Thermal Spray Center (CPT) University of Barcelona

研究了基体材料的力学性能对冷喷涂316L不锈钢单颗粒沉积行为的影响.结果表明,除硬度之外,弹性模量和Poisson比也会影响颗粒的沉积行为.这是由于基体性质对颗粒/基体的能量分配和结合机制造成了影响.其中,沉积颗粒的变形行为与颗粒吸收... 详细信息

研究了基体材料的力学性能对冷喷涂316L不锈钢单颗粒沉积行为的影响.结果表明,除硬度之外,弹性模量和Poisson比也会影响颗粒的沉积行为.这是由于基体性质对颗粒/基体的能量分配和结合机制造成了影响.其中,沉积颗粒的变形行为与颗粒吸收的能量有关,而沉积效率与基体吸收的能量及结合机制有关.根据沉积颗粒的变形行为,将基体分为2类:颗粒几乎不变形,此时基体的硬度和弹性模量皆低于颗粒材料,颗粒与基体的结合主要是机械咬合,推导出可用于推断相同颗粒在基体上沉积趋势的参数E_(para),并以AZ91镁合金为基体进行验证;颗粒发生强烈变形,此时基体的硬度或弹性模量高于颗粒材料,结合机制更为复杂,此时增加颗粒/基体新鲜表面接触面积有利于提高沉积效率.

关键词： 316L不锈钢基体力学性能沉积行为

Children with obesity have poorer circadian health as assessed by a global circadian health score

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World Journal of Pediatrics 2024年第8期20卷 787-800页

作者： María Rodríguez-Martín nuria Martínez-Lozano Vicente Santaclara-Maneiro Antonio Gris-Peñas Diego Salmerón Rafael Ríos Asta Tvarijonaviciute Marta Garaulet Department of Physiology Regional Campus of International ExcellenceUniversity of Murcia30100MurciaCPSpain Biomedical Research Instituteof Murcia IMIB-Arrixaca-UMUUniversity Clinical Hospital30120MurciaSpain Health Area of Lorca LorcaMurciaSpain Health and Social Sciences Department University ofMurciaMurciaSpain Consortium for Biomedical Research in Epidemiology and Public Health MadridSpain Interdisciplinary Laboratory of Clinical Analysis(Interlab-UMU) University of MurciaMurciaSpain Division of Sleep and Circadian Disorders Brigham and Women's Hospital(BWH)and Division of Sleep MedicineHarvard Medical SchoolBostonMA 02115USA

Background Circadian health refers to individuals’well-being and balance in terms of their circadian *** is influenced by external *** adults,a close relationship between circadian-related alterations and obesity has been ***,studies in children are scarce,and circadian health and its association with obesity have not been evaluated *** aimed to assess whether circadian health differed between children with and without obesity as determined by a global circadian score(GCS)in a school-age *** Four hundred and thirty-two children(7–12 years)were recruited in ***-invasive tools were used to calculate the GCS:(1)7-day rhythm of wrist temperature(T),activity(A),position(P),an integrative variable that combines T,A,and P(TAP);(2)cortisol;and(3)7-day food and sleep *** mass index,body fat percentage,waist circumference(WC),melatonin concentration,and cardiometabolic marker levels were *** Circadian health,as assessed by the GCS,differed among children with obesity,overweight,and normal weight,with poorer circadian health among children with *** with obesity and abdominal obesity had 3.54 and 2.39 greater odds of having poor circadian health,respectively,than did those with normal weight or low *** percentage of rhythmicity,a marker of the robustness of the TAP rhythm,and the amplitude,both components of the GCS,decreased with increasing *** lifestyle behaviors were involved in the association between circadian health and obesity,particularly protein intake(P=0.024),physical activity level(P=0.076)and chronotype(P=0.029).Conclusions The GCS can capture the relationship between circadian health and obesity in school-age *** intake,physical activity level,and chronotype were involved in this *** intervention based on improving circadian health may help to prevent childhood obesity.

关键词： Children Chronodisruption Circadian Lifestyle Obesity

A Tutorial on Federated Learning from Theory to Practice:Foundations,Software Frameworks,Exemplary Use Cases,and Selected Trends

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IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 824-850页

作者： M.Victoria Luzón nuria Rodríguez-Barroso Alberto Argente-Garrido Daniel Jiménez-López Jose M.Moyano Javier Del Ser Weiping Ding Francisco Herrera Department of Software Engineering Andalusian Research Institute in Data Science and Computational Intelligence(DaSCI)University of GranadaGranada 18071Spain Department of Computer Science and Artificial Intelligence Andalusian Research Institute in Data Science and Computational Intelligence(DaSCI)University of GranadaGranada 18071Spain Department of Communications Engineering University of the Basque Country(UPV/EHU)and also with TECNALIABasque Research&Technology Alliance(BRTA)Spain School of Information Science and Technology Nantong UniversityNantong 226019China

When data privacy is imposed as a necessity,Federated learning(FL)emerges as a relevant artificial intelligence field for developing machine learning(ML)models in a distributed and decentralized *** allows ML models to be trained on local devices without any need for centralized data transfer,thereby reducing both the exposure of sensitive data and the possibility of data interception by malicious third *** paradigm has gained momentum in the last few years,spurred by the plethora of real-world applications that have leveraged its ability to improve the efficiency of distributed learning and to accommodate numerous participants with their data *** virtue of FL,models can be learned from all such distributed data sources while preserving data *** aim of this paper is to provide a practical tutorial on FL,including a short methodology and a systematic analysis of existing software ***,our tutorial provides exemplary cases of study from three complementary perspectives:i)Foundations of FL,describing the main components of FL,from key elements to FL categories;ii)Implementation guidelines and exemplary cases of study,by systematically examining the functionalities provided by existing software frameworks for FL deployment,devising a methodology to design a FL scenario,and providing exemplary cases of study with source code for different ML approaches;and iii)Trends,shortly reviewing a non-exhaustive list of research directions that are under active investigation in the current FL *** ultimate purpose of this work is to establish itself as a referential work for researchers,developers,and data scientists willing to explore the capabilities of FL in practical applications.

关键词： Data privacy distributed machine learning federated learning software frameworks

Retailers,You Can Get Omni-Shopper’s Satisfaction!

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Journal of Business Administration Research 2020年第4期3卷 24-33页

作者： nuria Viejo-Fernández Sneha Saha Universidad de Oviedo Spain CHRIST(Deemed to be)University India

This paper evaluates the influence that information processing routes have on omni-shopping behavior,as well as analyzing the consequences of this behavior for retailers through a cognitive-affective approach.A sample of 705 mobile phone users was used for this *** results obtained using the binomial logit model in a first phase and later with an application of structural equations,reflect that omni-shoppers have a more planned purchasing behavior than those who develop a one-stop shopping *** search for information in a rational and deep way,spending time and *** for the consequences that the omni-channel behavior has for retailers,it has been found that those omni-shoppers who experience negative emotions with the retailer,have a low perceived value of the company and their satisfaction will also be negative.

关键词： Omni-channel customer behavior Routes to persuasion Emotions Perceived value Satisfaction Retail

Different strategies of treatment for uterine cervical carcinoma stage ⅠB2-ⅡB

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World Journal of Clinical Oncology 2014年第2期5卷 86-92页

作者： Lucas Minig María Guadalupe Patrono nuria Romero Juan Francisco Rodríguez Moreno Jesús Garcia-Donas Gynecologic Oncology Program Clara Campal Comprehensive Cancer CenterHM Hospitales28050 Madrid Spain Gynecologic Oncology Program Medical Oncology Department Clara Campal Comprehensive Cancer Center HM Hospitales28050 Madrid Spain

Uterine cervical cancer is the second most common gynecological malignancy. It is estimated that over 35% of tumors are diagnosed at locally advanced disease, stage ⅠB2-ⅡB with an estimated 5-year overall survival of 60%. During the last decades, the initial treatment for these women has been debated and largely varies through different countries. Thus, radical concurrent chemoradiation is the standard of care in United Sated and Canada, and neoadjuvant chemotherapy followed by radical surgery is the first line of treatment in some institutions of Europe, Asia and Latin America. Until today, there is no evidence of which strategy is better over the other. This article describe the evidence as well as the advantages and disadvantages of the main strategies of treatment for women affected by uterine cervical cancer stage ⅠB2-ⅡB.

关键词： Locally advanced cervical cancer Federation of Gynecology and Obstetrics stage ⅠB2-ⅡB Radiotherapy Neoajuvant chemotherapy Radical hysterectomy

Real-world data on the infliximab biosimilar CT-P13 (Remsima®) in inflammatory bowel disease

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World Journal of Clinical Cases 2021年第36期9卷 11285-11299页

作者： Jose María Huguet Xavier Cortés Marta Maia Bosca-Watts Marian Aguas nuria Maroto Lidia Martí Cirilo Amorós Jose María Paredes Department of Gastroenterology General University Hospital of ValenciaValencia 46014Spain Department of Gastroenterology Hospital de SaguntoSagunto 46520Spain Department of Gastroenterology Hospital Clinico Universitario de ValenciaValencia 46010Spain Department of Gastroenterology Hospital Universitario y Politecnico la Fe de ValenciaValencia 46026Spain Department of Gastroenterology Hospital de ManisesManises 46940Spain Department of Gastroenterology Hospital Comarcal Francesc de BorjaGandia 46702Spain Department of Gastroenterology Hospital Arnau de Vilanova de ValenciaValencia 46015Spain Department of Gastroenterology Hospital Universitario Doctor Peset de ValenciaValencia 46017Spain

BACKGROUND In recent years,biological therapies have revolutionized the management of inflammatory bowel disease(IBD);however,they are *** development of biosimilar products has allowed us to reduce healthcare costs and improve patients’access to these *** various studies support the similarity between infliximab and its biosimilar CT-P13 in terms of efficacy and safety,there are unmet needs regarding research on these agents in the context of *** To analyze clinical response rates to CT-P13 and adverse events in IBD patients treated in real-life *** An observational,prospective,multicenter study of IBD patients treated with CTP13 in clinical practice who were naïve to biological treatments or failed to respond to other anti-tumor necrosis factor drugs or had switched from infliximab originator was carried *** diagnostic or follow-up interventions were conducted on patients outside usual clinical *** primary endpoints were clinical response rates and number of adverse *** primary efficacy variable was the proportion of patients who were in clinical remission and/or had a clinical response at 3,6,9,and 12 *** A total of 220 IBD patients treated with CT-P13(Remsima®)were included in the study:87(40%)with ulcerative colitis and 133(60%)with Crohn’s *** age of the patients was 41.47(SD 15.74)years,and 58%were ***(9%)patients started treatment with CT-P13 after switching from *** the remaining 201 patients,142(65%)were naïve to biologic *** baseline,68.6%(n=138/201)of patients presented with active *** 12 mo of treatment,14.8%(n=12/81)presented with active disease,and 64.2%(n=52/81)were in clinical remission without *** 3 mo,75.5%(n=115/152)had a clinical response or achieved clinical remission,which was sustained for 12 mo(85.2%;n=69/81).There was a decrease in specific IBD indices at 3,6,9,and 12 mo(P<0.001).A total of 34 adverse events

关键词： Crohn’s disease Ulcerative colitis Inflammatory bowel disease Infliximab Biosimilar CT-P13

Cardiovascular risk factors and frontotemporal dementia: a case–control study

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Translational Neurodegeneration 2014年第1期3卷 98-103页

作者： Angel Golimstok nuria Cámpora Juan I Rojas María C Fernandez Cristina Elizondo Enrique Soriano Edgardo Cristiano Cognitive and Behavior Unit Department of NeurologyHospital Italiano de Buenos AiresPerón 42721411 Buenos AiresArgentina Department of Neurology Hospital Italiano de Buenos AiresBuenos AiresArgentina Epidemiology Department Hospital Italiano de Buenos AiresBuenos AiresArgentina

Cardiovascular risk factors(CRF)were widely described as related to *** are very few studies regarding this association in *** objective of the study was to compare the frequency of CRF in our population with FTD and controls.100 consecutive subjects with FTD diagnosis according to Lund-Manchester clinical criteria and 200 controls matched by age and sex were included between January 2003 to February 2007 at the Cognitive and Behavior Unit of Hospital Italiano de Buenos *** evaluation,laboratory tests,brain images(CT/MRI),neuropsychological and neuropsychiatric assessment were *** regression analysis was performed to analyze the association in CRF between FTD patients *** mean age in FTD was 69.7±0.9 vs.70.1±0.8 in controls(p 0.12).No difference in gender was observed between cases and *** differences were identified between patients and controls regarding hypertension(HTA)(65%vs.67,3%p 0.44);dyslipidemia(57%vs.54.7%p 0.74);obesity(39%vs.27.6%p 0.14)and hypothyroidism(26%vs.17.1%p 0.1).A significant difference was observed for Diabetes Mellitus(39%vs.22.6%p 0.001).In our population,Diabetes Mellitus was associated as an independent risk factor for *** our knowledge this is the first report in which CRF were evaluated prospectively in FTD *** studies are needed to confirm this finding in larger populations.

关键词： Cardiovascular risk factors Frontotemporal dementia Dementia FTD Diabetes DBT DM

Can the Rectum Balloon Minimize Rectal Toxicity During Irradiation Therapy of Prostate Cancer?

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Open Journal of Urology 2013年第1期3卷 37-43页

作者： nuria Landwehr Manfred Georg Krukemeyer Wolfgang Wagner Paracelsus-Klinik Osnabrück Osnabrück Germany

The irradiation of the rectum cancer occurs in many institutes by using a rectum balloon in order to reduce the mobility of the target organ and to distance the rectum from the target organ. The objective is to reduce side effects quantitatively as well as qualitatively. On the basis of two hospitals using identical techniques for the prostate irradiation with the sole difference of the rectum balloon the toxicity has been evaluated with the result of no significant difference between the cohorts concerning diarrhea, rectal pain symptoms and rectal bleedings. Therefore the authors consider the use of the rectum balloon prior to each irradiation not necessary for the reduction of toxicity particularly due to the fact that the application is often very painful, especially for patients with hemorrhoids. The rectum balloon as a tool for the reduction of the prostate mobility was not objective of this study.

关键词： Prostate Cancer Radiotherapy Rectum Balloon Side Effects