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植物环蛋白的检测方法与结构研究

植物环蛋白的检测方法与结构研究

第五届全国化学生物学学术会议

作者：唐军许文彦嵇长久潘蓄林 Conan Wang norelle l.daly David J.Craik 谭宁华中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室 Institute for Molecular Bioscience University of QueenslandBrisbane4072 Australia Institute for Molecular Bioscience University of QueenslandBrisbane4072 Australia Institute for Molecular Bioscience University of QueenslandBrisbane4072 Australia 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室

＜正＞植物环蛋白（cyclotides）是植物中一类富含半胱氨酸残基、由28～37个氨基酸残基通过肽键首尾连接的大环肽。环蛋白的胱氨酸结（cyclic cystine knot,CCK）结构特征使其具有抗化学降解和酶解的特性。同时环蛋白也具有广泛而多样... 详细信息

＜正＞植物环蛋白（cyclotides）是植物中一类富含半胱氨酸残基、由28～37个氨基酸残基通过肽键首尾连接的大环肽。环蛋白的胱氨酸结（cyclic cystine knot,CCK）结构特征使其具有抗化学降解和酶解的特性。同时环蛋白也具有广泛而多样的生物活性,如子宫收缩、抗 HIV、抗微生物活性、胰蛋白酶抑制剂、抗肿瘤活性等。因此,一方面环蛋白可能被直接用作药物

关键词：环蛋白检测方法堇菜科葫芦科

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α-芋螺毒素ltIA结构与功能的研究

α-芋螺毒素LtIA结构与功能的研究

4D imaging of void nucleation,growth,and coalescence from large and small inclusions in steel under tensile deformation

第九届中国生物毒素学术研讨会

作者：罗素兰 Kalyana Bharati Akondi 长孙东亭吴勇朱晓鹏胡远艳 Sean Christensen Cheryl Dowell norelle l.daly David J.Craik Ching-I Anderson Wang Richard J.lewis Paul F.Alewood J.Michael McIntosh 热带生物资源教育部重点实验室(海南大学)

＜正＞具有重要生理作用和临床研究意义的烟碱乙酰胆碱受体（nAChRs）介导众多中枢和外周神经系统的生理功能,包括学习、记忆、应答、镇痛和运动控制等。nAChRs激活多巴胺、去甲肾上腺素、五羟色胺、γ-氨基丁酸等多种神经递质的释放。...

＜正＞具有重要生理作用和临床研究意义的烟碱乙酰胆碱受体（nAChRs）介导众多中枢和外周神经系统的生理功能,包括学习、记忆、应答、镇痛和运动控制等。nAChRs激活多巴胺、去甲肾上腺素、五羟色胺、γ-氨基丁酸等多种神经递质的释放。已证实nAChRs是筛选诊断和治疗一大类重要疾病药物的关键靶点,这些疾病包括智障、成瘾、疼痛、帕金森症、精

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Journal of Materials Science & Technology 2022年第28期123卷 168-176页

作者： Yi Guo Timothy l.Burnett Samuel A.McDonald Michael.daly Andrew H.Sherry Philip J.Withers Shenyang National laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Henry Royce Institute Department of MaterialsUniversity of ManchesterM139PLUK European Synchrotron Radiation Facility(ESRF) 6 rue J Horowitz38000 GrenobleFrance National Nuclear laboratory Chadwick HouseBirchwood ParkWarringtonWA36AEUK

Samples of SA508 grade 3 nuclear pressure vessel ferritic steel were subjected to tensile straining whilst being simultaneously imaged in 3D in real time using high resolution,high frame rate time-lapse synchrotron computed tomography(CT).This enabled direct observation of void development from nucleation,through growth to coalescence and final failure validating many inferences made post-mortem or by theoretical models,as well as raising new *** sparse,large inclusions were found to nucleate voids at essentially zero plastic strain(consistent with zero interfacial strength);these became increasingly elongated with *** contrast,a high density of small spherical voids were found to nucleate from the sub-micron cementite particles at larger strains(>200%)only in the centre of the necked(high triaxiality)*** interfacial strength approaching 2100 MPa was inferred and soon after their nucleation,these small voids coalesce to form internal microcracks that lead to the final failure of the *** surprisingly,under these conditions of generally low triaxial constraint the large voids are simply cut across and appear to play no significant role in determining the final *** implications of these results are discussed in terms of ductile fracture behaviour and the Gurson model for ductile fracture.

关键词： Void growth Ductile fracture Synchrotron X-ray tomography 4D imaging Bainitic steel

Switchable carbamate coagulants to improve recycling ionic liquid from biomass solutions

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Green Chemical Engineering 2021年第4期2卷 384-391页

作者： Julia l.Shamshina Ying Qin Ken Belmore Daniel T.daly Robin D.Rogers Fiber and Biopolymer Research Institute Department of Plant and Soil ScienceTexas Tech UniversityLubbockTX79409USA Alabama Institute for Manufacturing Excellence The University of AlabamaTuscaloosaAL35487USA Department of Chemistry and Biochemistry The University of AlabamaTuscaloosaAL35487USA College of Arts&Sciences The University of AlabamaTuscaloosaAL35487USA Solutions Inc.P.O.Box 2206TuscaloosaAL35403USA

A reversible amine-carbamate approach has been developed to reduce the use of antisolvents such as water in the coagulation of biopolymers from ionic liquid(Il)solution and thus improve the economy of Il *** and chitin were recovered from 1-ethyl-3-methylimidazolium acetate([C_(2)mim][OAc])solution by introducing the miscible amines triethanolamine(TEA),ethylenediamine(EDA),or butylamine(BA)and bubbling CO_(2) at 40℃ and atmospheric pressure through the solutions to form carbamate salts in situ which resulted in biopolymer *** gave the best results because of its low boiling point and low viscosity,which benefited both biopolymer recovery and Il *** films and fibers could be formed by extrusion of an MCC/[C_(2)mim]-[OAc]solution into a coagulating bath comprised of a 1:1 M mixture of[C_(2)mim][OAc]and butylammonium butylcarbamate(BA-carbamate).The cellulose,Il,amine,and CO_(2) were easily separated,although the cellulose recovered required some water washings to remove traces of *** to 96.4%of the[C_(2)mim][OAc]could be recovered,76.2%from the coagulation bath and 20.2%from the water *** recycled Il was suitable for another cycle of cellulose dissolution and extrusion and 84.6%of the Il used for the second cycle was *** further work is needed,not the least of which will be reducing the amount of water needed for washing steps,some promising features of this process point the way for new directions for more economically viable Il recycling processes in biomass treatment with Ils.

关键词： Carbamate Ionic liquid Recovery Switchable Coagulation Biopolymers Carbamates Il recycle

Predicting phosphorus sorption isotherm parameters in soil using data of routine laboratory tests

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Pedosphere 2021年第5期31卷 694-704页

作者： Kathleen S.DUNNE Nicholas M.HOlDEN Karen daly Teagasc Johnstown CastleEnvironmental Research CentreCo.Wexford Y35TC97(Ireland) UCD School of Biosystems and Food Engineering University College DublinBelfieldDublin 4 D04VIW8(Ireland)

Knowledge of phosphorus(P)sorption dynamics across different soil types could direct agronomic and environmental management of *** objective of this study was to predict P isotherm parameters for a national soil population using data of routine laboratory *** and Freundlich sorption parameters were calculated from two different ranges(0-25 and 0-50 mg P l^(-1))using an archive of representative agricultural soil types from *** linear regression(MlR)identified labile forms of aluminium(Al)and iron(Fe),organic matter(OM),cation exchange capacity(CEC),and clay as significant *** and Freundlich sorption capacities,Freundlich affinity constant,and langmuir buffer capacity were predicted reliably,with R^(2) of independent validation>*** isotherm parameters were predicted from P sorbed at a single concentration of 50 mg P l^(-1)(S_(50)).An MlR prediction of P sorption maximum in the 0-50 mg P l-1 range was achieved,to an accurate standard,using S_(50),OM,and Mehlich-3 Fe(R^(2) of independent calibration and validation being 0.91 and 0.95,respectively).Using Giles’four shapes of isotherms(C,l,H,and S),l non-strict-and C-shaped isotherm curves accounted for 64% and 27% of the soils,*** clustering identified a separation of isotherm curves influenced by two ranges of Mehlich-3 *** with a low range of Mehlich-3 Al(2.5-698 mg kg^(-1))had no incidence of rapid sorption(C shape).Single point indices,Al,or available soil data make the regression approach a feasible way of predicting langmuir parameters that could be included with standard agronomic soil P testing.

关键词： available phosphorus binding fertilizer soil test sorption maximum

Effect of Medium Acidity and Photostability of 3-（4-Dimethyl- amino-phenyl）-l-（2,5-dimethyl-thiophen-3-yl）-propenone （DDTP）： A New Green Emitting laser Dye

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Chinese Journal of Chemistry 2011年第11期29卷 2557-2561页

作者： EI-daly, Samy A Asiri, Abdullah M. Khan, Salman A. Alamry, Khalid A. Hussein, Mahmoud A. Chemistry Department Faculty of Science King Abdulaziz University P.O. Box 80203 Jeddah 21589 Saudi Arabia Department of Chemistry Faculty of Science Tanta University 31527 Tanta Egypt The Center of ExcellenceforAdvanced Materials King Abdul Aziz University Jeddah 21589 P.O. Box 80203 Saudi Arabia Polymer Chemistry lab Chemistry Department Faculty of Science Assiut University Assiut 71516 Egypt

On the line of a previous work on the spectral properties of some of heteroaryl chalcone, the effect of medium acidity and photoreactivity of 3-（4-dimethylamino-phenyl）-l-（2,5-dimethyl-thiophen-3-yl）-propenone （DDTP） has been investigated in dimethylformamide and in chloromethane solvents such as methylenechloride, chloroform and carbon tetrachloride. The dye solution （ca. 5×10^-4 mol·l^-1 in DMF） gives a good laser emission in the range 470 --560 nm with emission maximum at 515 nm upon pumping by nitrogen laser （λex=337.1 nm）. The laser parameters such as gain coefficient （a）, emission cross section （Cre） and half life energy （E1/2） at maximum laser emission are also determined.

关键词： 3-(4-dimethylamino-phenyl)-1-(2,5-dimethyl-thiophen-3-yl)-propenone laser dyes effect of acidity possibility

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时尚木门中英文本

2002年

作者：（西）Ediciones daly S.l.编阿达译

本书介绍了各种时尚木门，包括28821型门、曼奴埃尔式门、limbe P3型镶玻璃内门、高品位仿古艺术门等。

ISBN: (纸本)753313138X

本书介绍了各种时尚木门，包括28821型门、曼奴埃尔式门、limbe P3型镶玻璃内门、高品位仿古艺术门等。

关键词：门木结构结构设计图集

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时尚铁门图集

Implementing physically active learning:Future directions for research,policy,and practice

2003年

作者：（西）Ediciones daly S.l.编阿达译

本书展示了百余种铁门的创意设计。每种铁门设计均配有设计公司的名称以及大门的参考型号等内容。

ISBN: (纸本)753313396X

本书展示了百余种铁门的创意设计。每种铁门设计均配有设计公司的名称以及大门的参考型号等内容。

关键词：门铁艺建筑设计图集

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Journal of Sport and Health Science 2020年第1期9卷 41-49,F0003页

作者： Andy daly-Smith Thomas Quarmby Victoria S.J.Archbold Ash C.Routen Jade l.Morris Catherine Gammon John B.Bartholomew Geir Kare Resaland Bryn llewellyn Richard Allman Henry Dorling School of Sport Leeds Beckett UniversityLeedsLS63QSUK School of Sport Exercise and Health SciencesLoughborough UniversityE152GZUK School of Health Promotion and Human Performance Eastern Michigan UniversityYpsilantiMI 48197USA Centre for Diet and Activity Research MRC Epidemiology UnitUniversity of CambridgeCambridgeCB21TNUK Department of Kinesiology and Health Education The University of Texas at AustinAustinTX 78705USA Center for Physically Active learning Faculty of EducationArts and SportsWestern Norway University of Applied SciencesSogndal5020 BergenNorway Tagtiv8 ltd and Move&learn LeedsWF27BSUK School of Sport Health and Social ScienceSolent UniversitySouthamptonSO 14 ORTUK

Purpose:To identify co-produced multi-stakeholder perspectives important for successful widespread physically active learning(PAl) adoption and ***:A total of 35 stakeholders(policymakers n=9;commercial education sector,n=8;teachers,n=3;researchers,n=15) attended a design thinking PAl *** formed 5 multi-disciplinary groups with at least 1 representative from each stakeholder *** group,facilitated by a researcher,undertook 2 tasks:(1) using Post-it Notes,the following question was answered:within the school day,what are the opportunities for learning combined with movement?and(2) structured as a washing-line task,the following question was answered:how can we establish PAl as the norm?All discussions were audio-recorded and *** analyses were conducted by 4 *** the analyses were complete,the main themes and subthemes were assigned to 4 predetermined categories:(1) PAl design and implementation,(2) priorities for practice,(3) priorities for policy,and(4) priorities for ***:The following were the main themes for PAl implementation:opportunities for PAl within the school day,delivery environments,learning approaches,and the intensity of *** main themes for the priorities for practice included teacher confidence and competence,resources to support delivery,and community of *** main themes for the policy for priorities included self-governance,the Office for Standards in Education,Children’s Services,and Skill,policy investment in initial teacher training,and curriculum *** main themes for the research priorities included establishing a strong evidence base,school-based PAl implementation,and a whole-systems ***:The present study is the first to identify PAl implementation factors using a combined multi-stakeholder *** achieve wider PAl adoption and implementation,future interventions should be evidence based and address implementation factors

关键词： Children Physical activity Physically active learning Policy School