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USING VARIABLE RELUcTANcE AcTUATION IN HIGH-PREcISION MAGNETIc LEVITATED LINEAR MOTORS-A cOMPARISON STUDY

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USING VARIABLE RELUCTANCE ACTUATION IN HIGH-PRECISION MAGNET...

一种基于直线开关磁阻电机的太阳跟踪系统设计(英文)

第二届亚洲机械电子学学术会议

作者： Eduardo Portabella Betrand norbert c.cheung Wai-chuen Gan Institute for Electrical Machines Traction and DrivesTechnical University of BraunschweigGermany Department of Electrical Engineering Hong Kong Polytechnic UniversityHunghomKowloonHong Kong ASM Assembly Automation 15 Kung Yip StreetKwai ChungNTHong Kong

＜正＞This paper assesses the feasibility of using magnetic levitated actuators in high precision linear motion *** arrangement has several advantages over traditional system, including friction-free,minimal maintenance, and the elimination of expensive mechanical propulsion and guidance *** paper first investigates existing technologies of magnetic *** it proposes a new magnetic levitation linear motor structure based on variable reluctance（VR）*** the paper performs simulations on the proposed structure and come out with some very interesting and exciting results.

关键词： Magnetic levitation variable reluctance linear motor high precision

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控制理论与应用 2008年第2期25卷 316-320页

作者：张宙赵世伟简伟铨孙振刚郭新展香港理工大学电机工程系中国香港 ASM香港有限公司中国香港特

本文提出了一个采用直线开关磁阻电机作为伺服机构的新颖的太阳跟踪系统.同时也提出了三种控制器配置方案以满足不同需要.按照电磁和机械特性,该太阳跟踪系统可分解为一个电磁子系统和一个机械子系统.整个系统的控制器采用级联控制结构... 详细信息

本文提出了一个采用直线开关磁阻电机作为伺服机构的新颖的太阳跟踪系统.同时也提出了三种控制器配置方案以满足不同需要.按照电磁和机械特性,该太阳跟踪系统可分解为一个电磁子系统和一个机械子系统.整个系统的控制器采用级联控制结构,分别对这两个子系统设计控制器.仿真结果表明了其建模方法和控制器设计的有效性.

关键词：直线开关磁阻电机太阳跟踪无传感器控制

Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis

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Science china(Life Sciences) 2024年第5期67卷 865-878页

作者： Wei Jia Yitao Li Kenneth c.P.cheung Xiaojiao Zheng School of chinese Medicine Hong Kong Baptist UniversityHong KongChina center for Translational Medicine and Shanghai Key Laboratory of Diabetes Mellitus Shanghai Sixth People's Hospital Affiliated to Shanghai JiaoTong University School of MedicineShanghai 200233China

Bile acids(BAs)play a crucial role in nutrient absorption and act as key regulators of lipid and glucose metabolism and immune *** the enterohepatic circulation,BAs are synthesized,metabolized,and reabsorbed,with a portion entering the vascular circulation and distributing *** allows BAs to interact with receptors in all major organs,leading to organ-organ interactions that regulate both local and global metabolic processes,as well as the immune *** review focuses on the whole-body effects of BA-mediated metabolic and immunological regulation,including in the brain,heart,liver,intestine,eyes,skin,adipose tissue,and *** BA synthesis and receptor signaling is a promising strategy for the development of novel therapies for various diseases throughout the body.

关键词： bile acid whole body metabolism immunity

Insights into the kinetics–morphology relationship of 1-, 2-, and 3D TiNb_(2)O_(7) anodes for Li-ion storage

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Nano Research 2024年第4期17卷 2770-2780页

作者： Wenlei Xu Yaolin Xu Veronika Grzimek Andrea Martin Thorsten Schultz Patrícia ARusso Yan Lu norbert Koch Nicola Pinna Department of chemistry IRIS Adlershof and the Center for the Science of Materials BerlinHumboldt-Universität zu BerlinBrook-Taylor-Str.212489 BerlinGermany Department of Electrochemical Energy Storage Helmholtz-Zentrum Berlin für Materialien und EnergieHahn-Meitner-Platz 114109 BerlinGermany Institut für Physik and IRIS Adlershof Humboldt-Universität zu BerlinBrook-Taylor-Str.212489 BerlinGermany Joint Research Group of Molecular Systems Helmholtz-Zentrum Berlin für Materialien und Energie12489 BerlinGermany

Understanding the influence of electrode material’s morphology on electrochemical behavior is of great significance for the development of rechargeable batteries,however,such studies are often limited by the inability to precisely control the morphology of electrode ***,nanostructured titanium niobium oxides(TiNb_(2)O_(7))with three different morphologies(one-dimensional(1D),two-dimensional(2D),and three-dimensional(3D))were synthesized via a facile microwave-assisted solvothermal *** influence of the morphological dimension of TiNb_(2)O_(7) as electrode material on the electrochemical performance in Li-ion batteries(LIBs)and the underlying correlation with the electrochemical kinetics were studied in detail.2D TiNb_(2)O_(7)(TNO-2D)shows a superior rate capability and cycling stability,associated with improved kinetics for charge transfer and Li-ion diffusion,compared to the 1D and 3D *** X-ray diffraction measurements reveal the structural stability and crystallographic evolution of TNO-2D upon lithiation and delithiation and correlate the Li-ion diffusion kinetics with the lattice evolution during battery charge and ***,carbon-coated TNO-2D achieves enhanced rate capability(205 mAh·g^(-1) at 50 c)and long-term cycling stability(87%after 1000 cycles at 5 c).This work provides insights into the rational morphology design of electrode materials for accelerated charge transfer and enhanced fast-charging capability,pushing forward the development of electrode materials for high-power rechargeable batteries in future energy storage.

关键词： morphological dimension electrochemical kinetics lithium-ion batteries TiNb_(2)O_(7) structural evolution

Activating Ru in the pyramidal sites of Ru_(2)P-type structures with earth-abundant transition metals for achieving extremely high HER activity while minimizing noble metal content

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carbon Energy 2024年第9期6卷 80-92页

作者： Sayed M.El-Refaei Patrícia A.Russo Thorsten Schultz Zhe-Ning chen Patrick Amsalem norbert Koch Nicola Pinna Department of chemistry and the center for the Science of Materials Berlin Humboldt-Universität zu BerlinBerlinGermany Max-Planck-Institut für chemische Energiekonversion Mülheim an der RuhrGermany Institut für Physik and center for the Science of Materials Berlin Humboldt-Universität zu BerlinBerlinGermany Helmholtz-Zentrum Berlin für Materialien und Energie GmbH BerlinGermany State Key Laboratory of Structural chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhouChina

Rational design of efficient pH-universal hydrogen evolution reaction catalysts to enable large-scale hydrogen production via electrochemical water splitting is of great significance,yet a challenging ***,Ru atoms in the Ru_(2)P structure were replaced with M=co,Ni,or Mo to produce M_(2-x)Ru_(x)P *** metals show strong site preference,with co and Ni occupying the tetrahedral sites and Ru the square pyramidal sites of the coRuP and NiRuP Ru_(2)P-type *** presence of co or Ni in the tetrahedral sites leads to charge redistribution for Ru and,according to density functional theory calculations,a significant increase in the Ru d-band *** a result,the intrinsic activity of coRuP and NiRuP increases considerably compared to Ru_(2)P in both acidic and alkaline *** effect is not observed for MoRuP,in which Mo prefers to occupy the pyramidal *** particular,coRuP shows state-of-the-art activity,outperforming Ru_(2)P with Pt-like activity in 0.5 M H_(2)SO_(4)(η10=12.3 mV;η100=52 mV;turnover frequency(TOF)=4.7 s^(-1)).It remains extraordinarily active in alkaline conditions(η10=12.9 mV;η100=43.5 mV)with a TOF of 4.5 s^(-1),which is 4x higher than that of Ru_(2)P and 10x that of Pt/*** increase in the co content does not lead to drastic loss of activity,especially in alkaline medium,where,for example,the TOF of co_(1.9)Ru_(0.1)P remains comparable to that of Ru_(2)P and higher than that of Pt/c,highlighting the viability of the adopted approach to prepare cost-efficient catalysts.

关键词： electrocatalysis ruthenium phosphide transition metal phosphonates

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon c.Daeschler Katelyn J.W.So Konstantin Feinberg Marina Manoraj Jenny cheung Jennifer Zhang Kaveh Mirmoeini JPaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

Projected changes in Extreme Event Indices for Alaska

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Atmospheric and climate Sciences 2024年第2期14卷 191-209页

作者： John E. Walsh Kyle Redilla Norman Shippee Lukas cheung David Bigelow Ronni Wilcock International Arctic Research center University of Alaska Fairbanks Fairbanks USA Stantec Ottawa Canada Stantec Montreal Canada Stantec Calgary Canada Two Bears Environmental consulting Anchorage USA

As climate has warmed in recent decades, Alaska has experienced a variety of high-impact extreme events that include heat waves, wildfires, coastal storms and freezing rain. Because the warming is projected to continue, it is essential to consider future changes when planning adaptation actions and building resilience. In this study, we synthesize information on future changes in extreme events in Alaska from an ensemble of regional climate model simulations performed as part of Arctic-cORDEX (coordinated Regional climate Downscaling Experiment). A set of 13 extreme event indices, based on those developed by the World climate Research Programme’s Expert Team on climate change Detection and Indices (ETccDI), are evaluated from the Arctic-cORDEX output for Alaska. Of the 13 indices, six pertain to temperature, five to total precipitation, one to wind and one to snow. The results for locations in seven different climate zones of Alaska include large increases (5˚c - 10˚c) in the temperature thresholds for the five hottest and coldest days of the year, and large increases in warm spell duration and decreases in cold spell duration. changes in the cold day temperature threshold are generally larger than the changes in the hot day temperature threshold, consistent with the projections of a stronger warming in winter than in summer in Alaska yearly maximum 1-day and 5-day precipitation amounts as well as the yearly number of consecutive wet days are projected to increase at all locations. The indices for heavy snow days and high-wind days show mixed changes, although the results indicate increases in heavy snow days at the more northern locations and increases in windy days at coastal locations. The changes in the extreme event indices continue through 2100 under the higher-emission (RcP 8.5) emission scenario, while the changes generally stabilize under the lower-emission (RcP 4.5) scenario. .

关键词： Extreme Events Temperature Precipitation Alaska climate

Genomics-driven derivatization of the bioactive fungal sesterterpenoid variecolin:creation of an unnatural analogue with improved anticancer properties

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Acta Pharmaceutica Sinica B 2024年第1期14卷 421-432页

作者： Dexiu Yan Jemma Arakelyan Teng Wan Ritvik Raina Tsz Ki chan Dohyun Ahn Vladimir Kushnarev Tsz Kiu cheung Ho ching chan Inseo choi Pui Yi Ho Feijun Hu Yujeong Kim Hill Lam Lau Ying Lo Law chi Seng Leung chun Yin Tong Kai Kap Wong Wing Lam Yim Nikolay S.Karnaukhov Richard Y.c.Kong Maria V.Babak Yudai Matsuda Department of chemistry City University of Hong KongHong Kong SARChina iGEM Team“Variecure” City University of Hong KongHong Kong SARChina Department of Biomedical Engineering City University of Hong KongHong Kong SARChina Moscow clinical Research center Named After A.S.Loginov Moscow 111123Russian Federation

A biosynthetic gene cluster for the bioactive fungal sesterterpenoids variecolin(1)and variecolactone(2)was identified in Aspergillus aculeatus ATcc *** production of 1 and 2 was achieved in Aspergillus oryzae by expressing the sesterterpene synthase VrcA and the cytochrome P450 ***,the replacement of VrcB with homologous P450s from other fungal terpenoid pathways yielded three new variecolin analogues(5-7).Analysis of the compounds’anticancer activity in vitro and in vivo revealed that although 5 and 1 had comparable activities,5 was associated with significantly reduced toxic side effects in cancer-bearing mice,indicating its potentially broader therapeutic *** study describes the first tests of variecolin and its analogues in animals and demonstrates the utility of synthetic biology for creating molecules with improved biological activities.

关键词： Animal studies Anticancer properties Biosynthesis Natural products Sesterterpenoids Synthetic biology Terpene synthases Variecolin

A Registry-Based Observational Study on the Maternal and Fetal Outcomes of cOVID-19 Patients in Hong Kong,china

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Maternal-Fetal Medicine 2024年第3期6卷 156-163页

作者： Hillary HY Leung Teresa WL Ma Florrie NY Yu Meliza cW Kong Tsz Kin Lo Pauline PL So Wing-cheong Leung Wendy Shu Ka Wang cheung Sakita Moungmaithong chi chiu Wang Liona c.Poon Department of Obstetrics and Gynaecology The Chinese University of HongKongHong Kong 999077China Department of Obstetrics and Gynaecology Queen Elizabeth HospitalHong Kong 999077China Department of Obstetrics and Gynaecology United Christian HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Princess Margaret HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Tuen Mun HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Kwong Wah HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Pamela Youde Nethersole Eastern HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Queen Mary HospitalHong Kong 999077China

Objective:To report the clinical maternal and fetal outcomes of pregnant women with coronavirus disease 2019(cOVID-19),along with any associated pregnancy complications,in Hong Kong,china,and to assess the impact of cOVID-19 vaccination on these ***:This prospective registry-based observational study included pregnant women who were recruited through convenient sampling and had a laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection with a cycle threshold(ct)value result available on admission to eight local hospitals in Hong Kong,*** on clinical symptoms,laboratory results,medical treatments,delivery timing and mode,and pregnancy complications were extracted from the Hospital Authority’s electronic medical record ***,fetal,and pregnancy outcomes were compared between unvaccinated pregnant women with cOVID-19 and those who had received at least one dose of cOVID-19 vaccine before *** continuous variables and categorical variables were analyzed using the Mann-Whitney U test and the Pearson’s chi-squared test respectively.A P value less than 0.05 was considered statistically ***:A total of 164 pregnant women were included,of whom 78(47.56%)were ***-19 was diagnosed before 28 weeks’gestation in 30(18.29%),while 134(81.71%)were diagnosed at or after 28 weeks’***-two(37.80%)women received at least one dose of cOVID-19 *** were no significant differences between vaccinated and unvaccinated groups in the time interval between cOVID-19 diagnosis and delivery,the ct value,and the gestational age at infection onset or delivery(P>0.05).The majority of women were symptomatic at diagnosis regardless of vaccination status 55(88.71%)in vaccinated group vs.78(76.47%)in unvaccinated group(P=0.052).Symptoms did not significantly differ between groups except for cough(62.90%vs.47.06%,P=0.049).The overall rate of severe cOVID-19 in pregnant women was *** t

关键词： cOVID-19 Maternal outcomes Fetal outcomes Pregnancy complications Severe cOVID-19