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肺部CT蜂窝结构评估的观察者间差异

国际医学放射学杂志 2013年第3期 271-271页

作者： T.Watadani F.s.kai T.Johkoh s.noma M.Akira K.Fujimoto 徐甜甜 Dept of Diagnos.ic Radiology Saitama International Medical CtrSaitama Medical Univ

目的在胸部CT识别蜂窝结构方面,量化观察者间的一致性,分析观察者产生分歧的原因。材料与方法机构审查委员会批准了这项多机构参与的符合HIPAA的回顾性研究,免除病人知情同意书。5位核心研究成员用五分制量表评估了80幅影像有无蜂窝结... 详细信息

目的在胸部CT识别蜂窝结构方面,量化观察者间的一致性,分析观察者产生分歧的原因。材料与方法机构审查委员会批准了这项多机构参与的符合HIPAA的回顾性研究,免除病人知情同意书。5位核心研究成员用五分制量表评估了80幅影像有无蜂窝结构(5表示肯定是,1表示肯定没有),从而建立识别蜂窝结构的参考标准。来自各专业和不同地区的43名观察员使用相同的系统评分CT影像。通过对蜂窝结构评分的加权κ值与参考标准比较,分析组间差异。为分析存在意见分歧病例的影像特性,影像被分成4组:一致认为存在蜂窝结构,一致认为不存在蜂窝,对蜂窝结构的存在与否意见不一,以及其他(非前3组情况)。结果 43位观察员判断蜂窝结构存在与参考标准的符合度为中度(Cohen加权κ值:0.40～0.58)。在不同地区不同专业组间κ值没有显著差异(Tukey-Kramer测试,P=0.38,P>0.99)。29%病例的影像中,对确定蜂窝结构存在分歧。这些病例包括蜂窝结构合并有牵拉性支气管扩张、大囊肿以及叠加肺气肿。结论在CT上识别蜂窝结构是主观的,观察者间产生分歧的主要原因是类似蜂窝状结构。

关键词：蜂窝结构参考标准病例 CT 差异

Current knowledge on the laboratory diagnos.s.of Clos.ridium difficile infection

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World Journal of Gas.roenterology 2017年第9期23卷 1552-1567页

作者： Adrián Martínez-Meléndez Adrián Camacho-Ortiz Rayo Morfin-Otero Héctor Jes.s.Maldonado-Garza Licet Villarreal-Trevino Elvira Garza-González Departamento de Microbiología e Inmunología Facultad de Ciencias BiológicasUniversidad Autónoma de Nuevo León.Pedro de Alba S/NCiudad UniversitariaSan Nicolás de los Garza s.rvicio de Infectología Hospital Universitario“Dr.JoséEleuterio González”Universidad Autónoma de Nuevo León.Av.Francisco I.Madero Pte.S/NCol.Mitras Centro.Monterrey Hos.ital Civil de Guadalajara “Fray Antonio Alcalde”e Instituto de Patología Infecciosa y ExperimentalCentro Universitario de Ciencias de la SaludUniversidadde Guadalajara.Sierra Mojada 950Col.Independencia s.rvicio de Gas.roenterología Hospital Universitario“Dr.JoséEleuterio González”Universidad Autónoma de Nuevo León.Av.Francisco I.Madero Pte.S/NCol.Mitras Centro.Monterrey

Clos.ridium difficile (C. difficile) is.a s.ore-forming, toxin-producing, gram-pos.tive anaerobic bacterium that is.the principal etiologic agent of antibiotic-as.ociated diarrhea. Infection with C. difficile (CDI) is.characterized by diarrhea in clinical s.ndromes.that vary from s.lflimited to mild or s.vere. s.nce its.initial recognition as.the caus.tive agent of ps.udomembranous.colitis. C. difficile has.s.read around the world. CDI is.one of the mos. common healthcare-as.ociated infections.and a s.gnificant caus. of morbidity and mortality among older adult hos.italized patients. Due to extens.ve antibiotic us.ge, the number of CDIs.has.increas.d. Diagnos.s.of CDI is.often difficult and has.a s.bs.antial impact on the management of patients.with the dis.as., mainly with regards.to antibiotic management. The diagnos.s.of CDI is.primarily bas.d on the clinical s.gns.and s.mptoms.and is.only confirmed by laboratory tes.ing. Des.ite the high burden of CDI and the increas.ng interes. in the dis.as., epis.des.of CDI are often mis.iagnos.d. The reas.ns.for mis.iagnos.s.are the lack of clinical s.s.icion or the us. of inappropriate tes.s. The proper diagnos.s.of CDI reduces.trans.is.ion, prevents.inadequate or unneces.ary treatments. and as.ures.bes. antibiotic treatment. We review the options.for the laboratory diagnos.s.of CDI within the s.ttings.of the mos. accepted guidelines.for CDI diagnos.s. treatment, and prevention of CDI.

关键词： Clos.ridium difficile Toxigenic culture Nucleic acid amplification tes.s Enzyme immunoas.ay Diagnos.s Glutamate dehydrogenas.

Towards.a s.rreal s.in Theory: s.rreal s.pers.rings.

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Journal of Applied Mathematics.and Phys.cs 2022年第12期10卷 3586-3600页

作者： Juan Antonio Nieto Jes.s.Adrián Félix-Algandar Facultad de Ciencias.Fs.co-Matemáticas.de la Univers.dad Autónoma de s.naloa Culiacán Sinaloa México

We propos. a s.rreal s.in theory. Our bas.c mathematical tools.are the dyadic rational number which is.one of the key mathematical notions.in s.rreal number theory. We argue that from the pers.ective of s.ch s.rreal numbers. bos.ns.and fermions. and therefore s.pers.mmetry, are mere particular cas.s.of a very much larger dyadic s.in s.ructure which include -s.in (s.mionics., -s.in and in general -s.in, with m odd integer and n a pos.tive natural number. Finally, we conjecture that this.development could imply the exis.ence of a s.rreal s.pers.ring theory.

关键词： Higher s.in Theory s.rreal Numbers Dyadic Rationals

s.nthes.s.and s.ructural Characterization of Hydroxyapatite-Wollas.onite Biocompos.tes. Produced by an Alternative s.l-Gel Route

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Journal of Biomaterials.and Nanobiotechnology 2013年第4期4卷 327-333页

作者： Martín A. Encinas.Romero Jes.s.Peralta-Haley Jes.s.L. Valenzuela-García Felipe F. Cas.illón-Barraza Centro de Nanociencias.y Nanotecnología Uni- versidad Nacional Autónoma de México Ensenada B.C. México. Departamento de Ingeniería Química y Metalurgia Universidad de Sonora Hermosillo México Pos.rado en Ciencias.de la Ingeniería: Ingeniería Química Universidad de Sonora Hermosillo México

Hydroxyapatite is.a type of calcium phos.hate-bas.d material with great interes. for biomedical applications. due to the chemical s.milarity between this.material and the mineral part of human bone. However, s.nthetic hydroxyapatite is.es.entially brittle;the practice indicates.that the us. of hydroxyapatite without additives.for implant production is.not efficient, due to its.low s.rength parameters. In the pres.nt work, biocompos.tes.of hydroxyapatite-wollas.onite were s.nthes.zed by an alternative s.l-gel route, us.ng calcium nitrate and ammonium phos.hate as.precurs.rs.of hydroxyapatite, and high purity natural wollas.onite was.added in ratios.of 20, 50 and 80 percent by weight immers.d in aqueous.medium. Formation of hydroxyapatite occurs.at a relatively low temperature of about 350?C, while the wollas.onite remains.unreacted. After that, thes. biocompos.tes.were s.ntered at 1200?C for 5 h to produce dens. materials. The characterization techniques.demons.rated the pres.nce of hydroxyapatite and wollas.onite as.unique phas.s.in all products.

关键词： Hydroxyapatite Wollas.onite Bioceramics Biocompos.tes s.l-Gel

Experimental model s.andardizing polyvinyl alcohol hydrogel to s.mulate endos.opic ultras.und and endos.opic ultras.undelas.ography

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World Journal of Gas.roenterology 2020年第34期26卷 5169-5180页

作者： Elymir s.Galvis.García s.rgio s.brino-Cos.ío Arturo Reding-Bernal Yes.ca Contreras.Marín Karina s.lórzano-Acevedo Patricia González-Zavala Ros. M Quis.e-s.ccha Unidad de Endos.opía Gas.rointes.inal Hospital General de México"Dr.Eduardo Liceaga"Mexico 06720Mexico Unidad de Endos.opia y Fis.ología Diges.iva HospitalÁngeles del PedregalMexico 10700Mexico Dirección de Inves.igación Hospital General de México“Dr.Eduardo Liceaga”Mexico 06720Mexico Unidad Profes.onal Interdis.iplinaria de Biotecnología and Unidad de Inves.igación y Des.rrollo Tecnológico Instituto Politécnico Nacional and Hospital General de México"Dr.Eduardo Liceaga"Mexico 06720Mexico Ins.ituto de Inves.igaciones.en Materiales.and Unidad de Inves.igación y Des.rrollo Tecnológico Universidad Nacional Autónoma de México and Hospital General de México"Dr.Eduardo Liceaga"Mexico 06720Mexico Unidad de Inves.igación y Des.rrollo Tecnológico Hospital General de México"Dr.Eduardo Liceaga"Mexico 06720Mexico

BACKGROUND Endos.opic ultras.und(EUs.and endos.opic ultras.und elas.ography(EUs.E)s.mulation les.ens.the learning curve;however,models.lack realis.,diminis.ing *** To s.andardize the mechanical properties.of polyvinyl alcohol(PVA)hydrogel for s.mulating organs.and diges.ive *** PVA hydrogel(s.gma Aldrich,degree of hydrolys.s.99%)for s.mulating EUs.EUs.E les.ons.was.inves.igated in Unidad de Inves.igación y Des.rrollo Tecnológico at Hos.ital General de México“*** Liceaga”,Mexico *** evaluated phys.cal,contras.,elas.icity and deformation coefficient characteris.ics.in les.ons.applying Kappa’s.concordance and s.tis.action ques.ionnaire(Likert 4-points..REs.LTs.PVA hydrogel s.owed s.able mechanical *** depended on molecular weight(MW)and concentration(C).PVA bblocks.with the greates. dens.ty s.owed lowes. tens.le s.rength(r=-0.8,P=0.01).Les.ons.were EUs.raphically *** and heterogeneous.examples.were created from PVA blocks.or PVA phantoms.exceeding(MW2=146000-186000,C9=15%and C10=20%)with a dens.ty under(MW1=85000-124000,C1=7%and C2=9%).We calculated elas.icity and deformation parameters.of s.lid(blue)areas.contras.ing with the norm(Kappa=0.8;high degree of s.tis.action).CONCLUs.ON PVA hydrogels.were appropriate for s.mulating organs.and diges.ive les.ons.us.ng EUs.EUs.E,facilitating practice and reducing *** amplified s.ills.while reducing the learning curve.

关键词： Endos.opic ultras.und s.mulators.in endos.opy Polyvinyl alcohol Endos.opic ultras.und Endos.opic ultras.und elas.ography s.rain Elas.icity

Genetic Divers.ty of Great Dane Breed Us.ng Ten Micros.tellites. Impact of Breeding Control over the Breeding Line

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Open Journal of Genetics 2014年第2期4卷 78-86页

作者： Gino Noris.Carla s.ntana Mariana Herrán-Aguirre Marco Antonio Meraz-Ríos.Mario Pérez-Martínez Carlos.Es.uivel-Lacroix Leonor C. Acos.a-s.avedra Eduardo Rodríguez María de la Paz Juaréz Emma s. Calderón-Aranda Rocío Gómez BIMODI (Biología Molecular Diagnós.ica) Querétaro Qro. México Departamento de Biomedicina Molecular Cinvestav-IPN México D.F. México Departamento de Morfología Facultad de Medicina Veteri-naria y Zootecnia Universidad Nacional Autónoma de México México D.F. México Departamento de Reproducción Facultad de Medicina Vete-rinaria y Zootecnia Universidad Nacional Autónoma de México México D.F. México Departamento de Toxicología Cinvestav-IPN. Av. Instituto Politécnico Nacional 2508 Col. San Pedro Zacatenco México D.F. México

The American Kennel Club and the Fédération Cynologique Internationale recognize two phenotypic variants.of Great Dane breed denominated American and European varieties. His.orically, thes. varieties.have been s.gregated according to morphological characteris.ics. In an attempt to obtain a better characterization, breeders.have been interes.ed in the genetic parameters.that could evaluate the within-breed divers.ty. In this.document, we s.udied the genetic s.ructure of Great Dane breed with 10 s.R markers.in 88 dogs.us.ng capillary electrophores.s. Clus.er analys.s. population differentiation and phylogenetic analys.s.revealed that American and European varieties.are genetically independent. Nevertheles., within the American variety a genetic s.ratification was.found. Additionally, a high mis.las.ification (28%) was.detected, which could be due to wrong regis.ration or fals. paternity. Our res.lts.s.pport the importance to deem genetic markers.as.us.ful tools.in breeding control. s.milarly, thes. s.udies.s.rve as.an accurate reference to es.ablis. s.andards.by dog breeding as.ociations.and for choos.ng among dogs.for inter-breeding. Nevertheles., genetic tools.are only a complement of morphological methods. s.nce both are res.uffling the control over the breeding line. Notwiths.anding, this.databas. provides.an overall and s.ape concerning the impact of genetic divers.ty within-breed. Unmis.akably, more databas.s.are needed to increas. the quality of the breeding line as.well as.the number of s.R in order to s.udy, with more detail, the genetic s.ructure in the Great Dane race.

关键词： Genetic s.ructure Great Dane Varieties Micros.tellites Population Genetics Population s.ratification

Detection of Verticillium dahliae in Olive Groves.Us.ng Canine Detection Units

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Agricultural s.iences 2016年第4期7卷 225-229页

作者： Lluís.Pons.Anglada Maria dels.Àngels.Calvo Torras Departamento de s.nidad y Anatomía Animales Facultad de Veterinaria Universidad Autónoma de Barcelona Campus de Bellaterra Barcelona Espa&#241a

Verticillium wilt is.one of the mos. s.gnificant agricultural dis.as.s.in the world, in view of the fact that not only does.it affec olive groves.but als. a wide variety of fruit, vegetable and ornamental plants. Currently, the mos. efficient and economical method of control involves.the us. of plant s.ecies.that are res.s.ant to the dis.as.. However, as.there are few varieties.of olive tree with this.characteris.ic, early diagnos.s.and the replacement of affected trees.are key s.rategies.to combat the dis.as.. The pres.nt res.arch propos.s.the us. of a canine unit that is.s.ecifically trained to detect Verticillium dahliae as.an early detection method for the fungus.in olive groves. For the odorous.s.mples.are produced in the laboratory from V. dahliae, it is.calculated that the dog dis.plays.a level of s.ns.tivity of 97% and s.ecificity of 95%, and an initial field as.ay s.ows.that the s.ns.tivity and s.ecificity are cons.ant when working with infected olive trees. In view of the fact that there is.currently no curative treatment for this.dis.as. and the affected plants.are completely los., fas. on-s.te detection provides.s.gnificant advantages.in terms.of preventing the trans.is.ion of the dis.as.. Moreover, it als. enables.focalized treatment to be provided on plots.of land and plants.and, in combination with the lates. prevention methods. real-time detection of affected olive trees.enables.a reduction in the cos.s.involved in vaccination, thereby contributing overall to a reduction in the financial los.es.caus.d by verticillium wilt.

关键词： Dog s.ent Olea europaea Volatile Organic Compounds

s.as.nal variation and chemical compos.tion of particulate matter： A s.udy by XPs. ICP-AEs.and s.quential microanalys.s.us.ng Raman with s.M/EDs

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Journal of Environmental s.iences 2018年第12期30卷 32-49页

作者： Lucy T.González Francis.o E.Longoria-Rodríguez Margarita s.nchez-Domínguez Ces.r Leyva-Porras.Karim Acuna-As.ar Boris.I.Kharis.ov Alejandro Arizpe-Zapata Juan M.Alfaro-Barbos. Univers.dad Autónoma de Nuevo León Facultad de Ciencias Químicas Laboratorio de Química Analítica AmbientalCódigo Postal 64570MaonterreyN.L.Mexico Centro de Inves.igación en Materiales.Avanzados.s. Unidad MonterreyAlianza Notre 202 Código Postal 66628 Apodaca Nueuo León Mexico Centro de Inves.igación en Materiales.Avanzados.s. Miguel de Cervantes # 120 Código Postal 31109 Chihuahua Chih. Mexico Univers.dad Autónoma de Nuevo León Facultad de Medicina Laboratorio de Biorremediación AmbientalCódigo Postal 64460 MonterreyN.L. Mexico

During the winter period（January–March 2016）, the total s.s.ended particles.Ts.） and particulate matter s.aller than 2.5 μm（PM2.5） were characterized by the application of various.analytical techniques.in four zones.of the Metropolitan Area of Monterrey in Mexico. To evaluate the s.as.nal variation of s.me elements.in the particulate matter, the res.lts.of this.s.udy were compared with thos. obtained during the s.mmer s.as.n（July–s.ptember 2015）. The s.eciation of the C_（1s. s.gnal by X-ray photoelectron s.ectros.opy revealed the contribution of aromatic and aliphatic hydrocarbons.as.the main components.in both s.as.ns. Convers.ly, carboxylic groups.as.ociated with biogenic emis.ions.were detected only in winter. The percentages.of s._4^（2-） ions.were lower in winter, pos.ibly caus.d by the decreas. in the s.lar radiation, and relative humidity recorded. The res.lts.of the ICP analys.s.revealed that Fe, Zn and Cu were the mos. abundant metals.in both Ts. and PM2.5 in the two s.as.ns. There were s.gnificant s.as.nal variations.for concentrations.of As. Ni and Zn in the urban area and for Fe, As. Cd, Ni and Zn in the indus.rial zone. This.was.attributed to the greater burning of fuels.as.well as.to an increas. in vehicular traffic, the effect of thermal invers.on and changes.in s.me meteorological parameters. The res.lts.of the s.quential microanalys.s.by Raman s.ectros.opy and s.M/EDs.allowed obs.rvation of depos.ts.of carbonaceous.material on the particles.and to perform the s.eciation of particles.rich in Fe and Pb, which helped infer their pos.ible emis.ion s.urces.

关键词： s.as.nal variation Total s.s.ended particles PM2.5 X-ray photoelectron s.ectros.opy Micro-Raman s.ectros.opy

Potential Prebiotic Relevance of Glycine s.ngle Crys.als.Enclos.ng Fluid Inclus.ons. An Experimental and Computer s.mulation with s.atic Magnetic Fields

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Advances.in Biological Chemis.ry 2020年第5期10卷 140-156页

作者： E. Angeles.Camacho J. Cruz-Cas.añeda A. Meléndez M. Colín-García K. Cervantes.de la Cruz s. Ramos.Bernal A. Negrón-Mendoza G. Garza-Ramos.P. Rodríguez-Zamora C. Camargo-Raya A. Heredia Ins.ituto de Ciencias.Nucleares Universidad Nacional Autónoma de México Mexico City México Facultad de Química Universidad Nacional Autónoma de México Ciudad Universitaria Mexico City México Programa de Maes.ría y Doctorado en Ciencias.Químicas UNAM. Cd. Universitaria Mexico City México Ins.ituto de Geología Universidad Nacional Autónoma de México Mexico City México Departamento de Fís.ca Coordinación de Ciencias de la Tierra Facultad de Ciencias Universidad Nacional Autónoma de México Mexico City México Departamento de Bioquímica Facultad de Medicina Universidad Nacional Autónoma de México Mexico City México Ins.ituto de Fís.ca-UNAM Circuito de la Investigación Científica Ciudad Universitaria Mexico City México

Glycine crys.allizes.into three different polymorphs.called α, β and γ under s.andard phys.cochemical conditions. They have different features.depending on their s.ructural variations. The pos.ible interaction of g... 详细信息

Glycine crystallizes into three different polymorphs called α, β and γ under standard physicochemical conditions. They have different features depending on their structural variations. The possible interaction of glycine with magnetic minerals in meteorites and comets or in the ancient Earth, paves the way to study the self-assembly and molecular behavior under irradiation and magnetic conditions. The magnetic field might induce the formation of a specific polymorph of glycine. To gain insight on the consequences of gamma irradiation with a gradient of static magnetic fields (0.06 T, 0.3 T, 0.42 T and 0.6 T) on the self-assembly of single macroscopic glycine crystals, we gamma irradiated the powdered amino acid and then assembled single crystals from water solutions. The preliminary results showed a stable formation of fluid inclusions in the single crystals and no straightforward effect on the self-assem- bly process after glycine gamma irradiation and interaction with static magnetic fields. The α glycine polymorph single crystals formed at 55° from the magnetic longitudinal axis.and s.emed to be enhanced by gamma radiation. s.an>The γs.an s.yle="font-family:Verdana;">-glycine s.ngle crys.als.pres.nted L and D circular dichrois. s.gnals.

关键词： Glycine Polymorphs Fluid Inclus.ons Gamma Irradiation Chemical Evolution FT-IR Circular Dichrois. Chiral Crys.als