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质子束放疗在中枢神经系统肿瘤患者中的应用趋势:美国国家癌症数据库分析(2004—2021年)

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国际肿瘤学杂志 2024年第7期51卷 424-431页

作者： saber Amin Chi Lin 美国内布拉斯加大学医学中心放射肿瘤科奥马哈NE 68198

目的评估分析质子束放疗(PBT)在美国中枢神经系统(CNS)肿瘤患者中的使用趋势以及相关影响因素。方法利用美国国家癌症数据库查询2004-2021年CNS肿瘤患者的资料,根据患者的病理组织学类型、确诊年龄、保险状况、家庭收入水平、受教育水... 详细信息

目的评估分析质子束放疗(PBT)在美国中枢神经系统(CNS)肿瘤患者中的使用趋势以及相关影响因素。方法利用美国国家癌症数据库查询2004-2021年CNS肿瘤患者的资料,根据患者的病理组织学类型、确诊年龄、保险状况、家庭收入水平、受教育水平、就诊医院类型等因素,探讨PBT在CNS肿瘤患者中的使用趋势。采用logistic多因素回归分析进行各种因素与PBT使用的相关性分析。结果共纳入192696例CNS肿瘤患者,接受PBT治疗患者为5901例(3.1%),其中年龄≥18岁患者4109例(69.6%)。PBT在CNS肿瘤中的使用率从2004年的1.0%增加到2021年的11.4%。在接受PBT治疗的患者中,胚胎瘤是最常见的儿童肿瘤,而星形细胞瘤是最常见的成人肿瘤。logistic多因素回归分析显示,近年来胶质母细胞瘤、室管膜瘤、髓母细胞瘤、生殖细胞瘤患者采用PBT治疗较星形细胞瘤患者增长更迅速。年龄<18岁、无其他合并症、有私人保险、家庭收入水平较高和近年来确诊也与PBT的使用呈正相关。结论在美国,儿童及青少年患者、无其他合并症、家庭收入水平较高、有私人保险、近年来确诊和特定肿瘤组织学类型的患者更有可能接受PBT治疗。PBT的使用率从2004年的1.0%增加到2021年的11.4%。然而,应接受PBT的患者数量与实际接受PBT的患者数量之间仍存在明显差距。

关键词：质子疗法中枢神经系统肿瘤美国国家癌症数据库

Novel self assembly behavior for γ-alumina nano.articles

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Particuology 2012年第6期10卷 744-750页

作者： Osama saber Physics Dept Faculty of ScienceKing Faisal UniversityAl-Hassa 31982P.O.Box 400Saudi Arabia Egyptian Petroleum Research Institute Nasr CityP.O.Box 11727CairoEgypt

In this study, self assembly behavior was induced for γ-alumina nano.articles by adsorption of dimethyl disulfide. Following this trend, we have developed a chemical process to obtain ＇y-alumina in the nano scale. Scanning electron microscopy images of the prepared γ-alumina showed big and strong agglomeration of the nano.articles indicating that these nano.articles have strong surface forces. Transmission electron microscopy images confirmed that the γ-alumina nano.articles 3-7 nm in size were converted to uniform spherical shape in the size range of 1-2 mm after shaking with dimethyl disulfide in the presence of n-hexane at room temperature. This phenomenon did not appear in the case of alumina in the micro scale. The surface properties of the prepared γ-alumina in the nano scale were characterized and compared with the γ-alumina in the micro scale by using low temperature nitrogen adsorption-desorption system, indicating that the specific surface area of the prepared γ-alumina nano.articles is larger than that of the γ-alumina in the micro scale. Furthermore, micro- and meso-pores were observed for the if-alumina nano.articles while only mesoporous structure was detected for the γ-alumina in the micro scale. These experimental results suggested that the self assembly behavior of the γ-alumina nano.articles may be due to the selective adsorption ofdimethyl disulfide in the micropores of these nano.articles to act as bridge linking the nano.articles.

关键词： γ-Alumina nano.articlesNovel self assembly behaviorScanning and transmission electronmicroscopy

Topology optimization and seismic collapse assessment of shape memory alloy(SMA)-braced frames:Effectiveness of Fe-based SMAs

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Frontiers of Structural and Civil Engineering 2022年第3期16卷 281-301页

作者： Aydin HASSANZADEH saber MORADI Department of Civil Engineering Ryerson UniversityToronto M5B 2K3Canada

This paper presents a seismic topology optimization study of steel braced frames with shape memory alloy(SMA)*** SMA-braced frames(SMA-BFs)with either Fe-based SMA or NiTi braces are determined in a performance-based seismic design *** topology optimization is performed on 5-and 10-story SMA-BFs considering the placement,length,and cross-sectional area of SMA bracing ***,strength,and performance-based design constraints are considered in the *** seismic response and collapse safety of topologically optimal SMA-BFs are assessed according to the FEMA P695 methodology.A comparative study on the optimal SMA-BFs is also presented in terms of total relative cost,collapse capacity,and peak and residual story *** results demonstrate that Fe-based SMA-BFs exhibit higher collapse capacity and more uniform distribution of lateral displacement over the frame height while being more cost-effective than NiTi braced *** addition to a lower unit price compared to NiTi,Fe-based SMAs reduce SMA material *** frames with Fe-based SMA braces,the SMA usage is reduced by up to 80%.The results highlight the need for using SMAs with larger recoverable strains.

关键词： topology optimization shape memory alloy Fe-based SMA steel braced frames performance-based seismic design collapse assessment

Highly efficient and easy synthesis of 2,4,6-triarylpyridines catalyzed by pentafluorophenylammonium triflate(PFPAT) as a new recyclable solid acid catalyst in solvent-free conditions

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Chinese Chemical Letters 2012年第4期23卷 419-422页

作者： Naser Montazeri saber Mahjoob Department of Chemistry Faculty of SciencesTonekabon BranchIslamic Azad University

Pentafluorophenylammonium triflate（PFPAT） was found to be a highly efficient catalyst for the preparation of 2,4,6- triarylpyridines from the reaction of acetophenone derivatives,aromatic aldehydes and ammonium *** methodology offers several advantages,such as short reaction time,high yields,simple procedure with an easy work-up and the absence of any volatile and hazardous organic *** addition,this catalytic system can act as an active,inexpensive,metal-free,recoverable and recyclable catalyst.

关键词： Pentafluorophenylammonium triflate 2 4 6-Triarylpyridines Solvent-free conditions Organo.atalyst Multi-component reaction

A Novel Fault Detection,Identification and Prediction Approach for Autonomous Vehicle Controllers Using SVM

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Automotive Inno.ation 2021年第3期4卷 301-314页

作者： Liam Biddle saber Fallah Connected Autonomous Vehicles Lab(CAV-Lab) Department of Mechanical Engineering SciencesUniversity of SurreySurrey GU27XHUK

Faults that develop in vehicle sensors have the potential to propagate unchecked throughout control systems if *** fault diagnosis and health monitoring algorithms will become necessary as automotive applications become more *** current fault diagnosis systems are not effective for complex systems such as autonomous cars where the case of simultaneous faults in different sensors is highly ***,this paper proposes a novel fault detection,isolation and identification architecture for multi-fault in multi-sensor systems with an efficient computational burden for real-time *** Vector Machine techniques are used to detect and identify faults in sensors for autonomous vehicle control *** addition,to identify degrading performance in a sensor and predict the time at which a fault will occur,a novel predictive algorithm is *** effectiveness and accuracy of the architecture in detecting and identifying multiple faults as well as the accuracy of the proposed predictive fault detection algorithm are verified through a MATLAB/IPG CarMaker co-simulation *** results present detection and identification accuracies of 94.94%and 97.01%,respectively,as well as a prediction accuracy of 75.35%.

关键词： Fault detection Fault identification Fault prediction Support Vector Machine

The adsorptive properties of UiO-66 towards organic dyes: A record adsorption capacity for the anionic dye Alizarin Red S.

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Chinese Journal of Chemical Engineering 2018年第4期26卷 731-739页

作者： Marwa S.Embaby saber D.Elwany Widiastuti Setyaningsih Mohamed R.saber Central laboratories Fayoum Drinking Water and Sanitation Company (FDWaSC) Food and Agricultural Product Technology Department Faculty of Agricultural Technology Gadjah Mada University Chemistry Department Faculty of Science Fayoum University

In order to decisively determine the adsorption selectivity of zirconium MOF(UiO-66) towards anionic versus cationic species, the adsorptive removal of the anionic dyes(Alizarin Red S.(ARS), Eosin(E), Fuchsin Acid(FA)and Methyl Orange(MO)) and the cationic dyes(Neutral Red(NR), Fuchsin Basic(FB), Methylene Blue(MB),and Safranine T(ST)) has been evaluated. The results clearly reveal a significant selectivity towards anionic dyes. Such an observation agrees with a plethora of reports of UiO-66 superior affinity towards other anionic species(Floride, PO_4^(3-), Diclofenac sodium, Methylchlorophenoxy-propionic acid, Phenols, CrO_4^(2-), SeO_3^(2-), and AsO_4^-). The adsorption process of ARS as an example has been optimized using the central composite design(CCD). The resultant statistical model indicates a crucial effect of both pH and sorbent mass. The optimum conditions were determined to be initial dye concentration 11.82 mg.L^(-1), adsorbent amount 0.0248 g, shaking time of 36 min and pH 2. The adsorption process proceeds via pseudo-second order kinetics(R^2= 0.999). The equilibrium data were fit to Langmuir and Tempkin models(R^2= 0.999 and 0.997 respectively). The results reveal an exceptional removal for the anionic dye(Alizarin Red S.) with a record adsorption capacity of400 mg·g^(-1). The significantly high adsorption capacity of UiO-66 towards ARS adds further evidence to the recently reported exceptional performance of MOFs in pollutants removal from water.

关键词： Adsorption Metal-organic frameworks Alizarin Red S. Dye removal UiO-66 Central composite design

Shaking table tests on the liquefaction-induced uplift displacement of circular tunnel structure

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Underground Space 2023年第3期10卷 182-198页

作者： saber no.ande Yaser Jafarian Abdolhosein Haddad Department of Civil Engineering Semnan UniversitySemnan 35131-19111Iran International Institute of Earthquake Engineering and Seismology(IIEES) Tehran 19537-14453Iran Deltares Boussinesqweg 1DelftSouth Hollands 2629 HVNetherlands

Underground structures are susceptible to float and move upward during earthquakes when located in a liquefiable soil *** are examples of this phenomenon in past major earthquake *** this study,the uplift of circular tunnels in a liquefiable sand layer was investigated with a series of shaking table *** research has focused on the buried depth of the tunnel,tunnel diameter,tunnel weight,liquefaction extent,uplift mechanism,and factor of safety against liquefaction-induced *** to the test results,the shallow buried depth,larger diameter,and lower weight can intensify the tunnel uplift,so the displacement in post-liquefaction time continues at the same rate as during the shaking *** to the shear-induced dilation,pore water pressure generation around the tunnel was reduced compared with that of the free *** excess pore water pressure dissipation in the soil overlying the uplifted tun-nel was significant,which leads to suction in the soil ***,the acceleration response of overlying soil with the uplifted tunnel was similar to that of the free ***,the soil acceleration response around the tunnel without uplift was similar to the base motion.

关键词： Liquefaction Tunnel uplift Underground structures Shaking table test Circular tunnel

Deciphering the puzzles of dog domestication

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Zoological Research 2020年第2期41卷 97-104页

作者： Zhe Zhang saber Khederzadeh Yan Li State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan School of Life SciencesYunnan UniversityKunmingYunnan 650091China State Key Laboratory of Genetic Resources and Evolution Germplasm Bank of Wild SpeciesKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China Kunming College of Life Science University of Chinese Academy of SciencesKunmingYunnan 650204China

The domestic dog,as a highly successful domestication model,is well known as a favored human *** its domestication history should provide great insight into our understanding of the prehistoric development of human culture and ***,investigation on the mechanisms underpinning the morphological and behavioral traits associated with canid domestication syndrome is of significance not only for scientific study but also for human medical *** development of a multidisciplinary canine genome database,which includes enormous omics data,has substantially improved our understanding of the genetic makeup of ***,we reviewed recent advances associated with the original history and genetic basis underlying environmental adaptations and phenotypic diversities in domestic dogs,which should provide perspectives on improving the communicative relationship between dogs and humans.

关键词： Dog Domestication history Adaptation Phenotypic diversity,Domestic legacy

Intrinsic luminescence centers in γ- and θ-alumina nano.articles

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Chinese Physics B 2017年第3期26卷 373-383页

作者： Abdolvahab Amirsalari saber Farjami Shayesteh Reza Taheri Ghahrizjani Nanostructures Labratory Department of Physics University of Guilan Department of Physics Optics and Laser Group Shahreza Branch Islamic Azad University

In this study, we investigate the photoluminescence （PL） properties of γ and θ-alumina nano.articles synthesized by the chemical wet method followed by annealing. The obtained experimental results indicate the presence of some favorable near ultraviolet （NUV）-orange luminescent centers for usage in various luminescence applications, such as oxygen vacancies （F, F＋, F2＋, and F2 centers）, OH related defects, cation interstitial centers, and some new luminescence bands attributed to trapped-hole centers or donor-acceptor centers. The energy states of each defect are discussed in detail. The defects mentioned could alter the electronic structure by producing some energy states in the band gap that result in the optical absorption in the middle ultraviolet （MUV） region. Spectra show that photoionazation of F and F2 centers plays a crucial role in providing either free electrons for the conduction band, or the photoconversions of aggregated oxygen va- cancies into each other, or mobile electrons for electrons-holes recombination process by the Shockley-Read-Hall （SRH） mechanism.

关键词： photoluminescence center defect oxygen vacancy emission