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Late Cretaceous biota and the Cretaceous-Paleogene(K--Pg)Boundary in Jiayin of heilongjiang,China

Global Geology 2011年第3期14卷 115-143页

作者： Sun G. Akhmetiev M. Markevich V. Ashraf A. R. Bugdaeva E. Godefroit P. Bolotsky Yu. Dong Z. M. Golovneva L. Yang h. X. Sun C. L. Sun Y. W. Quan C. Kodrul T. Kezina T. Johnson K. nishida h Dilcher D. L. harding I. Chen Y. J. Key-Lab for Evolution of Past Life MOEC(Jilin University) Changchun 130026 China College of Paleontology Shenyang Normal University Shenyang 110034 China Geological Institute of RAS Moscow 109017 Russia Institute of Biology and Soil Science FEB RAS Vladivostok 690022 Russia Institute of Geosciences University of Tuebingen Tuebingen 72074 Germany Royal Belgian Institute of Natural Sciences Dept. of Palaeontology B -1000 Bruxelles Belgium Amur Natural history Museum IGNE FEB RAS Blagoveschensk 675000 Russia IVPP Beijing 100044 China Research Center of Paleontology ＆ Stratigraphy Jilin University Changchun 130026 China Komarov Botanical Institute RAS St. -Petersburg 197376 Russia College of Geoexploration Science ＆ Technology Jilin University Changchun 130026 China Amur State University Blagoveshensk 675000 Russia Denver Museum o.f Natural Sciences Denver C0-90205 USA Chuo University Tokyo 112 Japan Indiana University Bloomington IN 47405 USA School of Ocean ＆ Geosciences University of Southampton Southampton S014 3ZH UK

An international cooperative study of the Late Cretaceous biota and non-marine strata including the Cretaceous-Paleogene(K--Pg) boundary in Jiayin near the heilongjiang River,China during 2002-2010,is summarized in this paper. The strata includes the Upper Cretaceous Yong'ancun-,Taipinglinchang-,Yuliang-zi-,and Furao formations,and the Paleocence Wuyun Formation consisting of Baoshantou Member and a Coalbearing Member. Seven palynological assemblages from Santonian to Paleocene are recognized,which is used for definition of the K--Pg boundary. Through the palynological analysis of three drilled boreholes (XhY-2005,2006,2008) in Xiaoheyan of western Jiayin,the K--Pg boundary is defined within 20. 00-20. 05 m in the borehole XhY-2006 (as a standard boundary) which is just between the top of Furao Formation (late Maasterichtian) and the base of Baishantou Member (early Danian) . These new research results are supported by paleo- magnetic,geochemical and other analyses,also. On the other hand,the presence of eight taxa of Maasterichtian dinosaurs (mostly hadrosaurids) have been recognized by the authors; and two mega-plant assemblages from the Yong'ancun Fm (Santonian) to Taipinglinchang Fm (Campanian) are confirmed. These research a-chievements indicate that the Upper Cretaceous-Paleocene in Jiayin can be well correlated to the strata in the neighboring Zeya-Bureja basin,Russia. The K--Pg boundary definited in Jiayin is the first well documented non-marine K--Pg boundary in China. Also the related paleoclimate,paleoenvironment and the mass extinctions in this area during the Cretaceous-Paleocene transition are also discussed.

关键词： Biota Late Cretaceous Paleogene K-Pg boundary heilongjiang River, Jiayin

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In Search of the Cretaceous-Tertiary Boundary in heilongjiang River Area of China

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Global Geology 2002年第2期7卷 105-113页

作者： Sun G. M.Akhmetiev Dong Z.M. A.R.Ashraf Sun Y.W. E.Bugdaeva D.L.Dilcher L.Golovneva I.harding K.Johnson T.Kezina T.Kodrul LU J.S. V.Markevich h.nishida h.Okada Park S.O. Sun C.L. Xiong X.Z. Xing Y.L. Zhou Z.L. Research Center of Paleontology&Stratigraphy Jilin UniversityChangchun130026China Geological Institute of Russian Academy of Sciences(RAS) Moscow109017Russia Institute of Geology&Paleontology Tuebingen UniversityTuebingenD-72076Germany Institute of Biology&Pedology FEBRASVladivostok690022Russia Florida Museum of Natural history University of FloridaGainesville FL32611-7800USA Botanical Institute of RAS St.-Petersburg197376Russia School of Ocean&Geosciences University of SouthamptonSouthamptonSO143ZH UK Denver Museum of Nature&Sciences Denver CO80205USA Amur Research Integrated Institute FEBRASBlagoveschesk675000Russia Chuo University Tokyo112-8551Japan Oyo Corporation Fukuoka811-1302Japan Dept.Of Geology Kyungpook National UniversityDaegu702-201Korea Geological Museum of heilongjiang Harbin150036China

A new geological section recognized in Baishantou of Jiayin,heilongjiang Province,China,was studied preliminarily in searching for the K/T *** early Paleocene florule characrerized by abundant Tiliaephyllum tsagajanicum leaves and its associated plants,was collected from the Baishantou Member(new member representing the lower part of the Paleocene Wuyun Formation)overlying the possible K/T boundary.A tuff bed was found from the upper part of the Furao Formation(uppermost Cretaceous)in this *** new findings imply that the K/T boundary is probable lying in the interval between the base of the Baishantou Member and the tuff bed,based on the correlation of the present strata with the stratotype of the Tsagajan Group spanning the K/T boundary in"Belaya Gara"of the Bureya Basin,*** early Paleocene florule from the Baishantou Member and the early-middle Maastrichtian dinosaurs found from the Yuliangzi Formation underlying the Furao Formation suggest that the Baishantou section is more promising for searching for the K/T boundary in this *** studies of the section is needed,integrating paleontological,biostratigraphic,geochemical,paleomagnetic,and sedimentary research would benefit our understanding the mass extinction event and biotic recovery in the heilongjiang River area,China,and even all of northeast Asia during the K/T boundary interval.

关键词： K/T boundary Early Paleocene Baishantou Member Jiayin heilongjiang River

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Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats

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World Journal of Gastroenterology 2014年第10期20卷 2641-2652页

作者： Atsuki Yamamoto Tomokazu Itoh Reishi Nasu Ryuichi nishida Pharmaceutical research laboratories Sakai Chemical Industry Co. Ltd. Kawachinagano Osaka 586-0006 Japan KATAYAMA SEIYAKUSYO Co. Ltd.Hirakata Osaka 573-1132 Japan Kaigen Pharma Co. Ltd.Doshomachi Chuo-ku Osaka 541-0045 Japan

AIM: To investigate the effects of sodium alginate (AL-Na) on indomethacin-induced small intestinal lesions in rats.

关键词： Sodium alginate Non-steroidal anti-inflammatory drugs Gastrointestinal mucosal injury Mucin Bacterial translocation

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Modeling three-dimensional forest structures to drive canopy radiative transfer simulations of bidirectional reflectance factor

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International Journal of Digital Earth 2018年第10期11卷 981-1000页

作者： Wei Yang hideki Kobayashi Xuehong Chen Kenlo nishida Nasahara Rikie Suzuki Akihiko Kondoh Center for Environmental Remote Sensing Chiba UniversityChibaJapan Department of Environmental Geochemical Cycle Research Japan Agency for Marine-Earth Science and TechnologyYokohamaJapan State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijingPeople’s Republic of China Faculty of Life and Environmental Sciences University of TsukubaTsukubaJapan

Three-dimensional(3-D)Monte Carlo-based radiative transfer(MCRT)models are usually used for benchmarking in intercomparisons of the canopy radiative transfer(RT)***,the 3-D MCRT models are rarely applied to develop remote sensing algorithms to estimate essential climate variables of forests,due mainly to the difficulties in obtaining realistic stand structures for different forest biomes over regional to global ***,some of important tree structure parameters such as canopy height and tree density distribution have been available *** enables to run the intermediate complexities of the 3-D MCRT *** consequently developed a statistical approach to generate forest structures with intermediate complexities depending on the inputs of canopy height and tree *** aims at facilitating applications of the 3-D MCRT models to develop remote sensing retrieval *** proposed approach was evaluated using field measurements of two boreal forest stands at Estonia and USA,*** demonstrated that the simulations of bidirectional reflectance factor(BRF)based on the measured forest structures agreed well with the BRF based on the generated structures from the proposed approach with the root mean square error(RMSE)and relative RMSE(rRMSE)ranging from 0.002 to 0.006 and from 0.7%to 19.8%,*** of the computed BRF with corresponding MODIS reflectance data yielded RMSE and rRMSE lower than 0.03 and 20%,*** the results from the current study are limited in two boreal forest stands,our approach has the potential to generate stand structures for different forest biomes.

关键词： Bidirectional reflectance factor remote sensing forest structure radiative transfer model

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Natural products and food components with anti-helicobacter pylori activities

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World Journal of Gastroenterology 2014年第27期20卷 8971-8978页

作者： hiroaki Takeuchi Vu Thu Trang Norihito Morimoto Yoshie nishida Yoshihisa Matsumura Tetsuro Sugiura Department of Clinical Laboratory Medicine Kochi Medical School School of Biotechnology and Food Technology Hanoi University of Science and Technology

The bacterial pathogen helicobacter pylori (h. pylori) colonizes in over half of the world’s population. h. pylori that establishes life-long infection in the stomach is definitely associated with gastro-duodenal diseases and a wide variety of non-gastrointestinal tract conditions such as immune thrombocytopenia. Triple therapy which consists of a proton pump inhibitor and combinations of two antibiotics (amoxicillin, clarithromycin or amoxicillin, metronidazol) is commonly used for h. pylori eradication. Recently, the occurrence of drug-resistant h. pylori and the adverse effect of antibiotics have severely weakened eradication therapy. Generally antibiotics induce the disturbance of human gastrointestinal microflora. Furthermore, there are inappropriate cases of triple therapy such as allergy to antibiotics, severe complications (liver and/or kidney dysfunction), the aged and people who reject the triple therapy. These prompt us to seek alterative agents instead of antibiotics and to develop more effective and safe therapy with these agents. The combination of these agents actually may result in lower a dose of antibiotics. There are many reports world-wide that non-antibiotic substances from natural products potentially have an anti-h. pylori agent. We briefly review the constituents derived from nature that fight against h. pylori in the literature with our studies.

关键词： Anti-helicobacter pylori effect Natural product Food component In vitro and in vivo effects human health helicobacter pylori treatment Combined effect

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The chemical mechanism of oxidative stress due to the non-transferrin-bound iron (NTBI)

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Advances in Bioscience and Biotechnology 2012年第7期3卷 1076-1086页

作者： Yuzo nishida Medical Research Institute Kanazawa Medical University Uchinada-machi Japan

Plasma iron is normally bound to the iron transport protein transferrin, but there are some iron ions not associated with transferrin. The latter ions are generally termed as non-transferrin-bound iron (NTBI) or labile plasma iron. The NTBI has been thought to play an important role in iron-induced cell damage with resultant peroxidation of cell membrane lipids and other biomolecules, and such oxidative damage is implicated as an important contributor in the pathogenesis of cancer, cardiovascular disease, aging and other degenerative disorders, but little is understood about the chemical composition of NTBI and the origin of toxicity due to NTBI. In this review, we demonstrated the several chemical models for NTBI, and elucidated the chemical mechanism of iron toxicity due to NTBI in human body on the basis of my concept on the mechanism of oxygen activation in biological oxygenases. This has lead to the conclusion that 1) NTBI are divided into two groups, water-in-soluble and water-soluble ones, 2) some of the water-soluble NTBI react with oxygen or hydrogen peroxide, changing these molecules to those exhibiting the reactivity similar to singlet oxygen (1△g), and this is the main reason for NTBI to induce the oxidative stress, and 3) the responsibility of hydroxyl radical or free singlet oxygen is negligible as a “reactive oxygen species” in the human body. Based on the discussions described in this article we have proposed a new technique to prevent the oxidative damage due to NTBI. In order to achieve the purpose, we have synthesized the new superpolyphenols which contain more than 100 molecules of catechol derivative in one polymeric compound;these are sometimes water-insoluble, and in another cases, water-soluble. We have observed that some of these compounds can eliminate NTBI effectively from the plasma, and also some of these derivatives can remove hydrogen peroxide from the solution. Thus, we can hope that our new super-polyphenols should depress greatly th

关键词： NTBI h2O2 Iron Toxicity nishida’s Reaction Super-Polyphenols Zinc(II) Ion Antioxidant

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SCALING PhOTOSYNThESIS FROM LEAF TO CANOPY AND REGIONAL SCALES:LINKING PLANT ECOPhYSIOLOGY,REMOTE SENSING AND MODELLING

SCALING PHOTOSYNTHESIS FROM LEAF TO CANOPY AND REGIONAL SCAL...

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第三世界生态高峰会

作者： h.MURAOKA K.nishida J.YOShINO h.KOIZUMI h.KOIZUMI University of Tsukuba h.KOIZUMI h.KOIZUMI

Spatial and temporal distributions of ecosystem-level photosynthesis are the critical determinant and therefore intensively required ecological phenomena for our understanding and for accurate evaluation climate change effects on regional carbon dynamics. Scaling approach from leaf ecophysiology to canopy and to regional ecosystems has been made by combining modelling and satellite remote *** some of these combined approaches have been providing information and evaluation of carbon dynamics in regional to global scales,we still need to find more accurate methodology for measuring the parameters responsible for ecosystem carbon gain by satellite remote *** achieve these challenges, we have been exploring two major works at the Takayama AsiaFlux site of Gifu University in Japan.(1)Linking leaf and canopy ecophysiology and spectral properties for remote *** leaf biochemical characteristics(photosynthesis,respiration,chlorophy11), leaf spectral properties,leaf morphology,shoot and canopy structure (leaf area and number),with their seasonality(phenology).Then these parameters were combined to estimate the spectral property,light disribution and photosynthesis at the canopy *** analyses were conducted by combining radiative transfer model(SAIL)and canopy photosynthesis *** using thus combined model,we obtained a set of data linking spectral profile and parameters which describes light-response of canopy photosynthesis such as maximum photosynthetic capacity and apparent quantum yield,by satellite remote *** preliminary scaling analyses showed that this approach can estimate ecosystem to regional scale photosynthesis along the biochemical theory of photosynthesis.(2)Linking ecosystem carbon dynamics model with numerical climate model for mountanous area. Most forest ecosystems are distributed in mountanous area in Japan. Such topographical characteristics provide us two major topics to be explored:(i)spatial variation of cli

关键词： SCALING PhOTOSYNThESIS FROM LEAF TO CANOPY AND REGIONAL SCALES:LINKING PLANT ECOPhYSIOLOGY,REMOTE SENSING AND MODELLING

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Fossil woods from the Upper Cretaceous to Paleocene of heilongjang(Amur)River area of China and Russia

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Global Geology 2011年第3期14卷 192-203,I0001-I0005页

作者： Kazuo Terada harufumi nishida SUN Ge Fukui Prefectural Dinosaur Museum Katsuyama Fukui 911-8601 Japan Faculty of Science and Engineering Chuo University Tokyo 112-8551 Japan Key-Lab for Evolution of Past Life ＆ Environment in NE Asia MOEC （ Jilin University） Changchun 130026 China College of Paleontology Shenyang Normal University Shenyang 110034 China

Fossil woods were collected from the Upper Cretaceous to Paleocene beds distributed around heilong- jang （Amur） River area of China and Russia. A total of 43 specimens were collected from Baishantou, Long- gushan, and Yong＇ancun in Jiayin, China, and 85 specimens from Zeya-Bureya Basin lying southeast of Blagoveshchensk in Russia. Selected specimens were sectioned and studied anatomically. The source deposits of almost all identifiable specimens belong to the Upper Cretaceous （Campanian） Taipinglinchang Formation and the Paleocene Wuyun Formation in China, and the Paleocene Upper Tsagayan Formation in Russia. Al- though the results obtained are still far from complete, the taxonomic composition of the fossil woods show marked stratigraphic differences between the two horizons beyond the K/T boundary in China. There is also a strong similarity in wood flora between the Wuyun Formation of China and the Upper Tsagayan Formation of Russia. All identified specimens from the Taipinglinchang Formation are Xenoxylon latiporosum, This is one of the stratigraphically younger records of Xenoxylon, which is a conifer morphogenus of uncertain affinity most common in the Triassic to Early Cretaceous. Only one specimen with possible derivation from either the Wuyun or the Maastriehtian Furao Formation in China was identified as Taxodioxylon sp. The Wuyun Formation yielded both conifers and dicotyledonous woods. The conifers include Taxodioxylon sequoianum of the Taxodiaceae, and Protopiceoxylon amurense, which is attributable to the extant genera Keteleeria or Nothotsuga of the Pinaeeac, both are at present endemic to China. At least two morphotypes of dicotyledonous woods were recognized, with one identified as el. hamamelidoxylon , and the other diffuse porous wood is characterized by numerous heterogeneous rays. From the Zeya-Buleya Basin of Russia, Taxodioxylon sequoianum and cf. hamamelidoxylon sp. were identified from the Upper Tsagayan Formation. The similarity of wood comp

关键词： K/T boundary fossil wood heilongjang Amur Zeya-Bureya Basin

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Associations among pain catastrophizing, muscle strength, and physical performance after total knee and hip arthroplasty

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World Journal of Orthopedics 2017年第4期8卷 336-341页

作者： Kazuhiro hayashi Masato Kako Kentaro Suzuki Keiko hattori Saori Fukuyasu Koji Sato Izumi Kadono Tadahiro Sakai Yukiharu hasegawa Yoshihiro nishida Department of Rehabilitation Nagoya University Hospital Department of Orthopaedic Surgery Nagoya University Graduate School and School of Medicine

AIM To investigate whether reductions in pain catastrophizing associated with physical performance in the early period after total knee arthroplasty(TKA) or total hip arthroplasty(ThA).METhODS The study group of 46 participants underwent TKA or ThA. The participants were evaluated within 7d before the operation and at 14d afterwards. Physical performance was measured by the Timed Up and Go(TUG) test, and 10-m gait time was measured at comfortable and maximum speeds. They rated their knee or hip pain using a visual analog scale(VAS) for daily life activities. Psychological characteristics were measured by the Pain Catastrophizing Scale(PCS). Physical characteristics were measured by isometric muscle strength of knee extensors and hip abductors on the operated side. The variables of percent changes between pre-and postoperation were calculated by dividing post-operation score by pre-operation *** Postoperative VAS and PCS were better than preoperative for both TKA and ThA. Postoperative physical performance and muscle strength were poorer than preoperative for both TKA and ThA. The percent change in physical performance showed no correlation with preoperative variables. In TKA patients, the percent change of PCS showed correlation with percent change of TUG(P = 0.016), 10-m gait time at comfortable speeds(P = 0.003), and 10-m gait time at maximum speeds(P = 0.042). The percent change of muscle strength showed partial correlation with physical *** percent change of VAS showed no correlation with physical performances. On the other hand, in ThA patients, the percent change of hip abductor strength showed correlation with percent change of TUG(P =0.047), 10-m gait time at comfortable speeds(P = 0.001),and 10-m gait time at maximum speeds(P = 0.021). The percent change of knee extensor strength showed partial correlation with physical performances. The percent change of VAS and PCS showed no correlation with physical *** Changes

关键词： Gait hip arthroplasty Knee arthroplasty Osteoarthritis Pain Pain management Postoperative care

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Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

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Cancer Communications 2024年第2期44卷 287-293页

作者： Kouya Shiraishi Atsushi Takahashi Yukihide Momozawa Yataro Daigo Syuzo Kaneko Takahisa Kawaguchi hideo Kunitoh Shingo Matsumoto hidehito horinouchi Akiteru Goto Takayuki honda Kimihiro Shimizu Masahiro Torasawa Daisuke Takayanagi Motonobu Saito Akira Saito Yuichiro Ohe Shun-ichi Watanabe Koichi Goto Masahiro Tsuboi Katsuya Tsuchihara Sadaaki Takata Tomomi Aoi Atsushi Takano Masashi Kobayashi Yohei Miyagi Kazumi Tanaka hiroyuki Suzuki Daichi Maeda Takumi Yamaura Maiko Matsuda Yoko Shimada Takaaki Mizuno hiromi Sakamoto Teruhiko Yoshida Yasushi Goto Tatsuya Yoshida Taiki Yamaji Makoto Sonobe Shinichi Toyooka Kazue Yoneda Katsuhiro Masago Fumihiro Tanaka Megumi hara Nobuo Fuse Satoshi S.Nishizuka Noriko Motoi Norie Sawada Yuichiro nishida Kazuki Kumada Kenji Takeuchi Kozo Tanno Yasushi Yatabe Kuniko Sunami Tomoyuki hishida Yasunari Miyazaki hidemi Ito Mitsuhiro Amemiya hirohiko Totsuka haruhiko Nakayama Tomoyuki Yokose Kazuyoshi Ishigaki Toshiteru Nagashima Yoichi Ohtaki Kazuhiro Imai Ken Takasawa Yoshihiro Minamiya Kazuma Kobayashi Kenichi Okubo Kenji Wakai Atsushi Shimizu Masayuki Yamamoto Motoki Iwasaki Koichi Matsuda Johji Inazawa Yuichi Shiraishi hiroyoshi Nishikawa Yoshinori Murakami Michiaki Kubo Fumihiko Matsuda Yoichiro Kamatani Ryuji hamamoto Keitaro Matsuo Takashi Kohno Division of Genome Biology National Cancer Center Research InstituteTokyoJapan Department of Clinical Genomics National Cancer Center Research InstituteTokyoJapan Laboratory for Statistical Analysis Center for Integrative Medical SciencesRIKENYokohamaJapan Department of Genomic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Laboratory for Genotyping Development Center for Integrative Medical SciencesRIKENYokohamaJapan Center for Antibody and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department of Medical Oncology and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Division of Medical AI Research and Development National Cancer Center Research InstituteTokyoJapan Center for Genomic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Medical Oncology Japanese Red Cross Medical CenterTokyoJapan Department of Thoracic Oncology National Cancer Center Hospital EastJapan Department of Thoracic Oncology National Cancer Center HospitalTokyoJapan Department of Cellular and Organ Pathology Graduate School of MedicineAkita UniversityAkitaJapan Department of Respiratory Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Division of General Thoracic Surgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department of General Surgical Science Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department of Gastrointestinal Tract Surgery Fukushima Medical University School of MedicineFukushimaJapan StaGen Co. LtdTokyoJapan Division of Thoracic Surgery National Cancer Center HospitalTokyoJapan Department of Thoracic Surgery National Cancer Center Hospital EastChibaJapan Division of Translational Informatics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear editor,Lung carcinoma is responsible for the highest fatal-ity rate among cancer-related deaths globally,with lung adenocarcinoma(LADC)emerging as the prevailing sub-type.

关键词： adenocarcinoma lung Lung

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