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Numerical multi-physical optimization of operating condition and current collecting setup for large-area solid oxide fuel cells

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Frontiers in Energy 2024年第3期18卷 356-368页

作者： Chengrong yu Zehua PAN Hongying ZHANG Bin CHEN Wanbing GUAN Bin MIAO Siew Hwa chan Zheng ZHONG Yexin ZHOU School of Science Harbin Institute of TechnologyShenzhen 518055China Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization Institute of Deep Earth Sciences and Green EnergyShenzhen UniversityShenzhen 518060China Key Laboratory of Advanced Fuel Cells and Electrolyzers Technology of Zhejiang Province Ningbo Institute of Materials Technology and Engineering of the Chinese Academy of SciencesNingbo 315201China Energy Research Institute at NTU(ERIAN) Nanyang Technological UniversitySingapore 639798Singapore

Due to the depletion of traditional fossil fuels and the aggravation of related environmental problems,hydrogen energy is gaining more attention all over the *** oxide fuel cell(SOFC)is a promising power generation technology operating on hydrogen with a high *** further boost the power output of a single cell and thus a single stack,increasing the cell area is an effective ***,it was recently found that further increasing the effective area of an SOFC single cell with a flat-tubular structure and symmetric double-sided cathodes would result in a lower areal *** this work,a multi-physical model is built to study the effect of the effective area on the cell *** distribution of different physical fields is systematically *** of the cell performance is also pursued by systematically tuning the cell operating condition and the current collection *** improvement of 42%is revealed by modifying the inlet gas flow rates and by enhancing the current *** the future,optimization of cell geometry will be performed to improve the homogeneity of different physical fields and thus to improve the stability of the cell.

关键词： solid oxide fuel cell(SOFC) large effective area flow rate discharge performance current collection

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Comparative transcriptome analysis between rhesus macaques(Macaca mulatta) and crab-eating macaques(M. fascicularis)

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Zoological Research 2024年第2期45卷 299-310页

作者： yu-Xiang Mao Yamei Li Zikun Yang ning Xu Shilong Zhang Xuankai Wang Xiangyu Yang Qiang Sun Yafei Mao Institute of Neuroscience State Key Laboratory of NeuroscienceCenter for Excellence in Brain Science&Intelligence TechnologyChinese Academy of SciencesShanghai 200031China Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology Shanghai 201210China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Genetic Evolution&Animal Models Chinese Academy of SciencesKunmingYunnan 650201China Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric DisordersMinistry of EducationShanghai Jiao Tong UniversityShanghai 200030China Zhiyuan College Shanghai Jiao Tong UniversityShanghai 200240China Center for Genomic Research International Institutes of MedicineFourth Affiliated HospitalZhejiang UniversityYiwuZhejiang 322000China

Understanding gene expression variations between species is pivotal for deciphering the evolutionary diversity in phenotypes. Rhesus macaques(Macaca mulatta, MMU)and crab-eating macaques(M. fascicularis, MFA) serve as crucial nonhuman primate biomedical models with different phenotypes. To date, however, large-scale comparative transcriptome research between these two species has not yet been fully explored. Here, we conducted systematic comparisons utilizing newly sequenced RNA-seq data from84 samples(41 MFA samples and 43 MMU samples)encompassing 14 common tissues. Our findings revealed a small fraction of genes(3.7%) with differential expression between the two species, as well as 36.5% of genes with tissue-specific expression in both macaques. Comparison of gene expression between macaques and humans indicated that 22.6% of orthologous genes displayed differential expression in at least two tissues. Moreover,19.41% of genes that overlapped with macaque-specific structural variants showed differential expression between humans and macaques. Of these, the FAM220A gene exhibited elevated expression in humans compared to macaques due to lineage-specific duplication. In summary,this study presents a large-scale transcriptomic comparison between MMU and MFA and between macaques and humans. The discovery of gene expression variations not only enhances the biomedical utility of macaque models but also contributes to the wider field of primate genomics.

关键词： Crab-eating macaques Rhesus macaques Comparative transcriptomics Biomedical models Nonhuman primates RNA-seq Duplicated genes

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Gut microbiome and serum metabolome analyses identify Bacteroides fragilis as regulators of serotonin content and PRL secretion in broody geese

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Journal of Integrative Agriculture 2024年第6期23卷 2033-2051页

作者： yu Zhang ning Zhou Jia Wu Lina Song Qiang Bao Kaiqi Weng Yang Zhang Wanwipa Vongsangnak Guohong Chen Qi Xu College of Animal Science and Technology Yangzhou UniversityYangzhou 225009China Joint International Research Laboratory of Agriculture&Agri-Product Safety of Ministry of Education Yangzhou UniversityYangzhou 225009China Department of Zoology Faculty of ScienceKasetsart UniversityBangkok 10900Thailand

Broody behavior is regulated by hypothalamic prolactin secretion,which seriously affects egg production in poulty *** studies have provided evidence that animal behavior is governed by dynamic bidirectional communication between specific gut bacteria and their host via the brain-gut-microbiome ***,little research focused on how the gut microbiota influence broody behavior in *** this study,Zhedong white geese in laying and brooding phases were *** differentially abundant bacteria in cecum were detected between brooding and laying geese through metagenomic analyses and 16S rRNA sequencing(P<0.05),and Bacteroides fragilis was specifically identified as a key driver species in the brooding ***,the serum metabolites were quantified,and the 313 differentially abundant metabolites were found between the two groups of different physiological *** were primarily enriched in the tryptophan metabolism *** correlation analyses revealed there was a significant positive correlation between *** abundance and the context of 11 tryptophan metabolism-related metabolites(such as serotonin,etc.)in broody geese,which hinted that those tryptophan metabolites might be produced or driven by ***,the serum hormone levels were also *** found there was a positive correlation between *** abundance and content of ***,prolactin secreted by the pituitary gland was greater in brooding geese than that in laying geese,which was also highly correlated with *** *** result implied that *** could promote the secretion of prolactin by the pituitary ***,the current study findings provided the information on gut microbiota influencing broody behavior,*** produced or driven more serum serotonin,and stimulated the pituitary gland to secret more prolactin,which potentially offered a new enlightenment for the intervention of broody behavior in pou

关键词： geese broody behavior gut microbiota serotonin prolactin

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Zonal activation of molecular carbon dioxide and hydrogen over dual sites Ni-Co-MgO catalyst for CO_(2) methanation:Synergistic catalysis of Ni and Co species

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Journal of Energy Chemistry 2024年第4期91卷 213-225页

作者： Zonglin Li Jianjun Chen yu Xie Junjie Wen Huiling Weng Mingxue Wang Jingyi Zhang Jinyan Cao Guocai Tian Qiulin Zhang Ping ning Faculty of Environmental Science and Engineering Kunming University of Science and TechnologyKunming 650500YunnanChina National-Regional Engineering Center for Recovery of Waste Gases from Metallurgical and Chemical Industries Kunming University of Science and TechnologyKunming 650500YunnanChina Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming 650093YunnanChina

An in-depth mechanism in zonal activation of CO_(2)and H2molecular over dual-active sites has not been revealed ***,Ni-Co-MgO was rationally constructed to elucidate the CO_(2)methanation *** abundant surface nickel and cobalt components as active sites led to strong Ni-Co interaction with charge transfer from nickel to ***,electron-enriched Coδ-species participated in efficient chemisorption and activation of CO_(2)to generate monodentate ***,plentiful available Ni0sites facilitated H2dissociation,thus CO_(2)and H2were smoothly activated at zones of Coδ-species and Ni0,*** in situ DRIFTS,quasi situ XPS,TPSR,and DFT calculations substantiated a new formate evolution mechanism via monodentate carbonate instead of traditional bidentate carbonate based on synergistic catalysis of Coδ-species and *** zonal activation of CO_(2)and H2by tuning electron behaviors of double-center catalysts can boost heterogeneous catalytic hydrogenation performance.

关键词： Zonal activation CO_(2) methanation Dual active sites Synergistic effect

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A review on vanadium extraction techniques from major vanadium-containing resources

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Rare Metals 2024年第9期43卷 4115-4131页

作者： Yin-Hui Wang Yi-Fan Wang yu-Ting Li chang Wu Xiu-Li Han ning-ning Zhao Ze-Kun Zhang Lei Dai Ling Wang Zhang-Xing He College of Mining Engineering North China University of Science and Technology Collaborative Innovation Center of Green Development and Ecological Restoration of Mineral Resources College of Chemical Engineering North China University of Science and Technology

The critical role of vanadium in metallurgy and the increasing commercialization of vanadium redox flow batteries have contributed to a rise in market demand for vanadium, emphasizing the need to ensure the sustainability of vanadium production. Converter vanadium slag and stone coal, generated during the smelting process of vanadium–titanium magnetite, serve as primary raw materials for vanadium extraction. This paper reviews the process mineralogy of converter vanadium slag and stone coal, encompassing the chemical and physical phase compositions of the raw materials and the state of vanadium occurrence. The aim is to establish a theoretical foundation for the mechanistic study of the vanadium extraction techniques and to provide a reference for the optimization of the process afterward. This paper systematically summarizes the current vanadium extraction technology from converter vanadium slag, covering roasting,direct leaching, sub-molten salt method, and the technology and research status of vanadium extraction from stone coal. Most importantly, it identifies key issues in the current vanadium extraction techniques and challenges faced in actual production, based on the analysis of the current vanadium extraction process and mechanism research. The forward feasibility and prospects for the development of vanadium extraction technology are outlined.

关键词： Vanadium

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Robotic-assisted low anterior resection for rectal cancer shows similar clinical efficacy to laparoscopic surgery: A propensity score matched study

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1558-1570页

作者： Shen-Xiang Long Xin-ning Wang Shu-Bo Tian yu-Fang Bi Shen-Shuo Gao yu Wang Xiao-Bo Guo Department of Gastrointestinal Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina Department of Endocrinology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina Department of Nursing The People’s Hospital of Zhangqiu AreaJinan 250200Shandong ProvinceChina Medical Center for Gastrointestinal Surgery Weifang People’s HospitalWeifang 261000Shandong ProvinceChina

BACKGROUND Rectal cancer ranks as the second leading cause of cancer-related mortality worldwide,necessitating surgical resection as the sole treatment *** the years,there has been a growing adoption of minimally invasive surgical techni-ques such as robotic and laparoscopic *** surgery represents an innovative modality that effectively addresses the limitations associated with traditional laparoscopic *** previous studies have reported favo-rable perioperative outcomes for robot-assisted radical resection in rectal cancer patients,further evidence regarding its oncological safety is still *** To conduct a comparative analysis of perioperative and oncological outcomes between robot-assisted and laparoscopic-assisted low anterior resection(LALAR)*** The clinical data of 125 patients who underwent robot-assisted low anterior resection(RALAR)and 279 patients who underwent LALAR resection at Shandong Provincial Hospital Affiliated to Shandong First Medical University from December 2019 to November 2022 were retrospectively *** performing a 1:1 propensity score matching,the patients were divided into two groups:The RALAR group and the LALAR group(111 cases in each group).Subsequently,a comparison was made between the short-term outcomes within 30 d after surgery and the 3-year survival outcomes of these two *** Compared to the LALAR group,the RALAR group exhibited a significantly earlier time to first flatus[2(2-2)d vs 3(3-3)d,P=0.000],as well as a shorter time to first fluid diet[4(3-4)d vs 5(4-6)d,P=0.001].Additionally,the RALAR group demonstrated reduced postoperative indwelling catheter time[2(1-3)d vs 4(3-5)d,P=0.000]and decreased length of hospital stay after surgery[5(5-7)d vs 7(6-8)d,P=0.009].Moreover,there was an observed increase in total cost of hospitalization for the RALAR group compared to the LALAR group[10777(10780-11850)dollars vs 10550(8766-11715)dollars,P=0.012].No signi

关键词： Rectal cancer Robotic surgical procedures Laparoscopy Low anterior resection Clinical efficacy

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Preparation and Performance of Organically Modified Montmorillonite Composite Separation Membrane

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Journal of Wuhan University of Technology(Materials Science) 2024年第5期39卷 1100-1107页

作者： LIU Peng BI yuanyuan CHEN Shaowei WAN Ye yu yunwu FANG Yanfeng GU Yaxin LI Feihong TANG ning LI Xiangyu School of Materials Science and Engineering Shenyang Jianzhu UniversityShenyang 110168China

A new composite separation membrane was developed by using organically modified montmorillonite(OMMT)as an *** effects of OMMT on the modification and properties of PVDF composite membranes were *** is found that different kinds and amounts of OMMT into the casting solution can obviously change the pure water flux,separation performance and hydrophilicity of composite membrane in varying *** the TA/PDA-MMT was 0.5 wt%,the pure water flux of the membrane reached the maximum,which was 584.7 L/(m^(2)·h),about 6 times that of the original *** OMMT/PVDF composite membrane had good hydrophilicity and stability in the treatment of oily *** development of novel OMMT/PVDF composite membrane will provide a new idea for solving the problem of oily wastewater treatment.

关键词： membrane montmorillonite composite wastewater

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Appendiceal intussusception complicated by adenocarcinoma of the cecum:A case report

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World Journal of Clinical Cases 2024年第8期12卷 1461-1466页

作者： yu Long Yi-ning Xiang Fei Huang Lei Xu Xiao-yun Li yun-Huan Zhen Department of Colorectal Surgery The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550001Guzihou ProvinceChina Department of Colorectal Surgery Guizhou Medical UniversityGuiyang 550001Guizhou ProvinceChina Department of Pathology The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550001Guizhou ProvinceChina

BACKGROUND Appendiceal intussusception is a pathological condition in which the appendix is inverted into the cecum,which may cause symptoms that resemble those of other gastrointestinal disorders and may induce intestinal *** rarity of this case presentation is the co-occurrence of appendiceal intussusception and cecal adenocarcinoma,a combination that to our knowledge has not previously been reported in the medical *** case provides new insights into the complexities of diagnosing and managing overlapping *** SUMMARY A 25-year-old woman presented with persistent periumbilical pain and bloody *** initial biopsy showed cecal cancer;however,subsequent colonoscopy and computed tomography findings raised the suspicion of appendiceal intussus-ception,which was later confirmed *** unique case was charac-terized by a combination of intussusception and adenocarcinoma of the *** intervention included a laparoscopic right hemicolectomy,which led to the histopathological diagnosis of mucinous adenocarcinoma with appendiceal *** patient recovered well postoperatively and was advised to initiate adjuvant *** case highlights not only the importance of considering appendiceal intussusception in the differential diagnosis,but also the possibility of appendicitis and the atypical presentation of neoplastic *** Physicians should consider the possibility of appendiceal intussusception in cases of atypical appendicitis,particularly when associated with neoplastic presentation.

关键词： Appendiceal intussusception Appendicitis Cecal cancer Target signs Misdiagnosis Case report

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Traditional Chinese medicines derived natural inhibitors of ferroptosis on ischemic stroke

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Chinese Journal of Natural Medicines 2024年第8期22卷 746-755页

作者： WANG Yongliang LAN Xiaobing LIU ning MA Lin DU Juan WEI Wei HAI Dongmei WU Jing yu Jianqiang LIU yue School of Pharmacy Ningxia Medical UniversityYinchuan 750000China ningxia Key Laboratory of Drug Development and Generic Drug Research Ningxia Medical UniversityYinchuan 750000China ningxia Characteristic Traditional Chinese Medicine Modern Engineering Research Center Ningxia Medical UniversityYinchuan 750000China College of Basic Medical Sciences Ningxia Medical UniversityYinchuan 750000China

Ischemic stroke(IS)is a globally prevalent cerebrovascular disorder resulting from cerebral vessel occlusion,leading to significant morbidity and *** intricate pathological mechanisms underlying IS complicate the development of effective therapeutic ***,a form of programmed cell death(PCD)characterized by iron overload and accumulation of lipid peroxidation products,has been increasingly recognized as a key contributor to IS *** Chinese medicines(TCMs)have long been utilized in the management of IS,prompting extensive research into their potential as sources of natural ferroptosis *** review investigates the critical role of ferroptosis in IS and provides a comprehensive analysis of current research on natural ferroptosis inhibitors identified in TCMs,aiming to lay a theoretical groundwork for the development of innovative anti-IS therapies.

关键词： Ischemic stroke Traditional Chinese medicines Natural inhibitors Ferroptosis

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Hydrocarbon gas huff-n-puff optimization of multiple horizontal wells with complex fracture networks in the M unconventional reservoir

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Petroleum Science 2024年第2期21卷 1018-1031页

作者： Hao-Chuan Zhang Yong Tang You-Wei He Yong Qin Jian-Hong Luo yu Sun ning Wang De-Qiang Wang State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500SichuanChina CNPC Research Institute of Petroleum Exploration&Development Beijing100083China Southwest Oil&Gas Field Company PetroChinaChengdu610051SichuanChina State Key Laboratory of Offshore Oil Exploitation CNOOC Research Institute Co.LtdBeijing100027China

The oil production of the multi-fractured horizontal wells(MFHWs) declines quickly in unconventional oil reservoirs due to the fast depletion of natural energy. Gas injection has been acknowledged as an effective method to improve oil recovery factor from unconventional oil reservoirs. Hydrocarbon gas huff-n-puff becomes preferable when the CO_(2) source is limited. However, the impact of complex fracture networks and well interference on the EOR performance of multiple MFHWs is still unclear. The optimal gas huff-n-puff parameters are significant for enhancing oil recovery. This work aims to optimize the hydrocarbon gas injection and production parameters for multiple MFHWs with complex fracture networks in unconventional oil reservoirs. Firstly, the numerical model based on unstructured grids is developed to characterize the complex fracture networks and capture the dynamic fracture ***, the PVT phase behavior simulation was carried out to provide the fluid model for numerical simulation. Thirdly, the optimal parameters for hydrocarbon gas huff-n-puff were obtained. Finally, the dominant factors of hydrocarbon gas huff-n-puff under complex fracture networks are obtained by fuzzy mathematical method. Results reveal that the current pressure of hydrocarbon gas injection can achieve miscible displacement. The optimal injection and production parameters are obtained by single-factor analysis to analyze the effect of individual parameter. Gas injection time is the dominant factor of hydrocarbon gas huff-n-puff in unconventional oil reservoirs with complex fracture networks. This work can offer engineers guidance for hydrocarbon gas huff-n-puff of multiple MFHWs considering the complex fracture networks.

关键词： Unconventional oil reservoir Complex fracture network Hydrocarbon gas huff-n-puff Parameter optimization Numerical simulation

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