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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2351-2357页

作者： Jing-Jie Wang Fen-Ming Zhang Wei Chen hua-Tuo Zhu ning-Long Gui Ai-Qing Li Hong-Tan Chen Department of Gastroenterology The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina

BACKGROUND Extragastric lesions are typically not misdiagnosed as gastric submucosal tumor(SMT).However,we encountered two rare cases where extrinsic lesions were misdiagnosed as gastric *** SUMMARY We describe two cases of gastric SMT-like protrusions initially misdiagnosed as gastric SMTs by the abdominal contrast-enhanced computed tomography(CT)and endoscopic ultrasound(EUS).Based on the CT and EUS findings,the patients underwent gastroscopy;however,no tumor was identified after incising the gastric *** surgical exploration revealed no gastric lesions in both patients,but a mass was found in the left triangular ligament of the *** patients underwent laparoscopic tumor resection,and the postoperative diagnosis was hepatic *** During EUS procedures,scanning across different layers and at varying degrees of gastric cavity distension,coupled with meticulous image analysis,has the potential to mitigate the likelihood of such misdiagnoses.

关键词： Submucosal tumor Extragastric compression Endoscopic ultrasonography Computed tomography Hemangioma of the left triangular ligament of the liver Case report

Machine Learning-Based Research on Tensile Strength of SiC-Reinforced Magnesium Matrix Composites via Stir Casting

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Acta Metallurgica Sinica(English Letters) 2024年第3期37卷 453-466页

作者： Zhihong Zhu Wenhang ning Xuanyang Niu Yuhong Zhao Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijing 100083China School of Materials Science and Engineering Collaborative Innovation Center of Ministry of Education and Shanxi Province for High-Performance Al/Mg Alloy MaterialsNorth University of ChinaTaiyuan 030051China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004China

SiC is the most common reinforcement in magnesium matrix composites,and the tensile strength of SiC-reinforced magnesium matrix composites is closely related to the distribution of *** a uniform distribution of SiC requires fine control over the parameters of SiC and the processing and preparation ***,due to the numerous adjustable parameters,using traditional experimental methods requires a considerable amount of experimentation to obtain a uniformly distributed composite ***,this study adopts a machine learning approach to explore the tensile strength of SiC-reinforced magnesium matrix composites in the mechanical stirring casting *** analyzing the influence of SiC parameters and processing parameters on composite material performance,we have established an effective predictive ***,six different machine learning regression models have been developed to predict the tensile strength of SiC-reinforced magnesium matrix *** validation and comparison,our models demonstrate good accuracy and reliability in predicting the tensile strength of the composite *** research findings indicate that hot extrusion treatment,SiC content,and stirring time have a significant impact on the tensile strength.

关键词： Machine learning Stirring casting Magnesium matrix composite Tensile strength

Unveiling evapotranspiration patterns and energy balance in a subalpine forest of the Qinghai-Tibet Plateau:observations and analysis from an eddy covariance system

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Journal of Forestry Research 2024年第3期35卷 175-188页

作者： Niu Zhu Jinniu Wang Dongliang Luo Xufeng Wang Cheng Shen ning Wu ning Zhang Binghui Tian Aihong Gai Chengdu Institute of Biology Chinese Academy of SciencesChengdu 610041People's Republic of China College of Resources and Environmental Sciences Gansu Agricultural UniversityLanzhou 730070People's Republic of China Mangkang Ecological Monitoring Station Tibet Ecological Security Barrier Ecological Monitoring NetworkQamdo 854500People's Republic of China Northwest Institute of Eco Environmental Resources Chinese Academy of SciencesLanzhou 730000People's Republic of China

Evapotranspiration is an important parameter used to characterize the water cycle of *** under-stand the properties of the evapotranspiration and energy balance of a subalpine forest in the southeastern Qinghai-Tibet Plateau,an open-path eddy covariance system was set up to monitor the forest from November 2020 to October 2021 in a core area of the Three Parallel Rivers in the Qing-hai-Tibet *** results show that the evapotranspira-tion peaked daily,the maximum occurring between 11:00 and 15:*** factors had significant effects on evapotranspiration,among them,net radiation the greatest(R^(2)=0.487),and relative humidity the least(R^(2)=0.001).The energy flux varied considerably in different seasons and sensible heat flux accounted for the main part of turbulent *** energy balance ratio in the dormant season was less than that in the growing season,and there is an energy imbalance at the site on an annual time scale.

关键词： Evapotranspiration Energy balance Subalpine forest Three Parallel Rivers region Southeast Qinghai-Tibet Plateau

Improvement of the piezoelectricity of PVDF-HFP by CoFe_(2)O_(4)nanoparticles

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Nano Materials Science 2024年第2期6卷 201-210页

作者： Dan Lei ning Hu Liangke Wu Alamusi Huiming ning Yang Wang Zhaonan Jin Yaolu Liu College of Aerospace Engineering Chongqing UniversityChongqing400044China State Key Laboratory of Reliability and Intelligence Electrical Equipment School of Mechanical EngineeringHebei University of TechnologyTianjin300401China

High piezoelectric composite films composed of poly(vinylidene fluoride-co-hexafluoropropylene)(PVDF-HFP)and ferromagnetic cobalt ferrite(CoFe_(2)O_(4))(0.00 wt%to 0.2 wt%)are prepared by a solution casting method accompanied by uniaxial stretching and high electric field *** decisive effect of the poling electric field on the power generating capability was confirmed by the *** pure PVDF-HFP films,when the maximum electric field Emax is 120 MV/m,the calibrated open circuit voltage reaches 2.93 V,which is much higher than those poled at lower electric fields(70 MV/m:1.41 V;90 MV/m:2.11 V).Furthermore,the addition of CoFe_(2)O_(4)also influences the piezoelectricity *** the samples containing 0.15 wt%CoFe_(2)O_(4),the calibrated open circuit voltage increases to the maximum value of 3.57 ***,the relative fraction of theβ-phase and the crystallinity degree are 99%and 48%,*** effects of CoFe_(2)O_(4)nanoparticles on initial crystallization,uniaxial stretching and high electric field poling are investigated by XRD,FTIR and DSC.

关键词： PVDF-HFP CoFe_(2)O_(4)nanoparticles Piezoelectricity Nanocomposite

Dynamic analysis and bifurcation control of a delayed fractional-order eco-epidemiological migratory bird model with fear effect

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International Journal of Biomathematics 2024年第3期17卷 1-33页

作者： Caihong Song ning Li College of Sciences Northeastern University 110819 ShenyangLiaoningP.R.China

In this paper,a new delayed fractional-order model including susceptible migratory birds,infected migratory birds and predators is proposed to discuss the spread of diseases among migratory *** of predators is considered in the model,as fear can reduce the reproduction rate and disease transmission rate among ***,some basic mathematical results of the proposed model are ***,time delay is regarded as a bifurcation parameter,and the delay-induced bifurcation conditions for such an uncontrolled system are established.A novel periodic pulse feedback controller is proposed to suppress the bifurcation *** is found that the control scheme can successfully suppress the bifurcation behavior of the system,and the pulse width can be arbitrarily selected on the premise of ensuring the control *** with the traditional time-delay feedback controller,the control scheme proposed in this paper has more advantages in practical application,which not only embodies the advantages of low control cost and easy operation but also caters to the periodic changes of the *** proposed control scheme,in particular,remains effective even after the system has been disrupted by a *** simulation verifies the correctness of the theoretical results.

关键词： Delayed fractional-order migratory birds fear Hopf bifurcation periodic pulse feedback

Network pharmacology study and in vitro experimental validation of Xiaojianzhong decoction against gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第9期16卷 3932-3954页

作者： Guo-Qing Chen Yi Nan Na ning Shi-Cong huang Yu-Ting Bai Zi-ying Zhou Gu Qian Wei-Qiang Li Ling Yuan College of Pharmacy Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina Key Laboratory of ningxia Minority Medicine Modernization Ministry of EducationNingxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina Department of Pharmacy Ningxia Chinese Medicine Research CenterYinchuan 750021Ningxia Hui Autonomous RegionChina Department of Pharmacy General Hospital of Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina Department of Chinese Medical Gastroenterology The Affiliated TCM Hospital of Ningxia Medical UniversityWuzhong 751100Ningxia Hui Autonomous RegionChina

BACKGROUND Cancer is one of the most serious threats to human health *** treatments such as surgery and chemotherapy are associated with some *** recent years,traditional Chinese medicine treatment has been increasingly advocated by patients and attracted attention from clinicians,and has become an indispensable part of the comprehensive treatment for gastric *** To investigate the mechanism of Xiaojianzhong decoction(XJZ)in the treatment of gastric cancer(GC)by utilizing network pharmacology and experimental validation,so as to provide a theoretical basis for later experimental *** We analyzed the mechanism and targets of XJZ in the treatment of GC through network pharmacology and ***,we verified the impact of XJZ treatment on the proliferative ability of GC cells through CCK-8,apoptosis,cell cycle,and clone formation ***,we performed Western blot analysis and real-time quantitative PCR to assess the protein and mRNA expression of the core *** XJZ mainly regulates IL6,PTGS2,CCL2,MMP9,MMP2,HMOX1,and other target genes and pathways in cancer to treat *** inhibition of cell viability,the increase of apoptosis,the blockage of the cell cycle at the G0/G1 phase,and the inhibition of the ability of cell clone formation were observed in AGS and HGC-27 cells after XJZ *** addition,XJZ induced a decrease in the mRNA expression of IL6,PTGS2,MMP9,MMP2,and CCL2,and an increase in the mRNA expression of *** significantly inhibited the expression of IL6,PTGS2,MMP9,MMP2,and CCL2 proteins and promoted the expression of the heme oxygenase-1 *** XJZ exerts therapeutic effects against GC through multiple components,multiple targets,and multiple *** findings provide a new idea and scientific basis for further research on the molecular mechanisms underlying the therapeutic effects of XJZ in the treatment of GC.

关键词： Xiaojianzhong decoction Gastric cancer Network pharmacology Molecular mechanism In vitro experiment

Therapeutic effects of Lingguizhugan decoction in a rat model of high-fat diet-induced insulin resistance

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World Journal of Diabetes 2024年第6期15卷 1291-1298页

作者： Xiao-Ming Liu Shi-Qing Yuan ying ning Shi-Jia Nie Xu-Qiong Wang Hong-Yi Jia Xiu-Li Zheng Department of Basic Medicine School of Basic Medicine Chengdu University of Traditional Chinese MedicineChengdu 611137Sichuan ProvinceChina Department of Clinical Medicine Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina

BACKGROUND Lingguizhugan(LGZG)decoction is a widely used classic Chinese medicine formula that was recently shown to improve high-fat diet(HFD)-induced insulin resistance(IR)in animal *** To assess the therapeutic effect of LGZG decoction on HFD-induced IR and explore the potential underlying *** To establish an IR rat model,a 12-wk HFD was administered,followed by a 4-wk treatment with *** determination of IR status was achieved through the use of biochemical tests and oral glucose tolerance *** a targeted metabolomics platform to analyze changes in serum metabolites,quantitative real-time PCR(qRT-PCR)was used to assess the gene expression of the ribosomal protein S6 kinase beta 1(S6K1).RESULTS In IR rats,LGZG decreased body weight and indices of hepatic *** effectively controlled blood glucose and food intake while protecting islet *** analysis revealed significant differences between the HFD and HFDLGZG *** intervention reduced branched-chain amino acid *** of IR-related metabolites such as tryptophan,alanine,taurine,and asparagine decreased *** may be linked to amino acids due to the contemporaneous increase in S6K1 expression,as shown by *** Our study strongly suggests that LGZG decoction reduces HFD-induced *** may activate S6K1 via metabolic *** findings lay the groundwork for the potential of LGZG as an IR treatment.

关键词： Lingguizhugan decoction High-fat diet-induced insulin resistance Amino acid metabolism S6K1

Post-transcriptional regulation of grain weight and shape by the RBP-A-J-K complex in rice

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Journal of Integrative Plant Biology 2024年第1期66卷 66-85页

作者： Ding Ren Hui Liu Xuejun Sun Fan Zhang Ling Jiang ying Wang ning Jiang Peiwen Yan Jinhao Cui Jinshui Yang Zhikang Li Pingli Lu Xiaojin Luo State Key Laboratory of Genetic Engineering and MOE Engineering Research Center of Gene Technology School of Life SciencesFudan UniversityShanghai 200438China State Key Laboratory of Crop Stress Adaptation and Improvement School of Life SciencesHenan UniversityKaifeng 475004China MOE Key Laboratory of Crop Physiology Ecology and Genetic Breeding College of AgronomyJiangxi Agricultural UniversityNanchang 330045China State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural Sciences(CAAS)Beijing 100081China College of Agronomy Anhui Agricultural UniversityHefei 230036China

RNA-binding proteins(RBPs)are components of the post-transcriptional regulatory system,but their regulatory effects on complex traits remain *** an integrated strategy involving map-based cloning,functional characterizations,and transcriptomic and population genomic analyses,we revealed that RBP-K(LOC_Os08g23120),RBP-A(LOC_Os11g41890),and RBP-J(LOC_Os10g33230)encode proteins that form an RBP-A-J-K complex that negatively regulates rice yield-related *** of the RBP-A-J-K complex indicated RBP-K functions as a relatively non-specific RBP chaperone that enables RBP-A and RBP-J to function ***,RBP-J most likely affects GA pathways,resulting in considerable increases in grain and panicle lengths,but decreases in grain width and *** contrast,RBP-A negatively regulates the expression of genes most likely involved in auxin-regulated pathways controlling cell wall elongation and carbohydrate transport,with substantial effects on the rice grain filling process as well as grain length and ***,RBP-K is relatively ancient and highly conserved,whereas RBP-J and RBP-A are more ***,the RBP-A-J-K complex may represent a typical functional model for many RBPs and protein complexes that function at transcriptional and post-transcriptional levels in plants and animals for increased functional consistency,efficiency,and versatility,as well as increased evolutionary *** results clearly demonstrate the importance of RBP-mediated post-transcriptional regulation for the diversity of complex ***,rice grain yield and quality may be enhanced by introducing various complete or partial loss-of-function mutations to specific RBP genes using clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein 9 technology and by exploiting desirable natural tri-genic allelic combinations at the loci encoding the components of the RBP-A-J-K complex through marker-assisted select

关键词： GL11 grain weight and shape post-transcriptional regulation RNA-binding proteins

A Comprehensive Approach to Improving Children’s and Adolescents’Mental Health

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China CDC weekly 2024年第40期6卷 1017-1021页

作者： ning Zhang School of Public Health and the Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou CityZhejiang ProvinceChina

The Increasing Prevalence of Mental Health Problems Among Children and Adolescents in China The prevalence of mental health issues among children and adolescents in China has continuously increased over the past few *** to a recent national psychiatric epidemiological survey of 17,524 school-aged children and adolescents,the prevalence of mental health disorders was 17.5%[95%confidence interval(CI):17.2%,18.0%].

关键词： prevalence Children Health

Near-infrared Emissive 1,2-Dioxetane-based Chemiluminescent Probes

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Chemical Research in Chinese Universities 2024年第5期40卷 806-823页

作者： CHEN yingqi BUDIANTA Richard ning yingying Spin-X Institute School of Chemistry and Chemical EngineeringSchool of Biomedical Sciences and EngineeringState Key Laboratory of Luminescent Materials and DevicesGuangdong-Hong Kong-Macao Joint Laboratory of Optoelectronic and Magnetic Functional MaterialsSouth China University of TechnologyGuangzhou510641P.R.China

Chemiluminescence,a phenomenon emitting light from chemical reactions rather than photon absorption,has gained significant interest for applications in bioimaging and biosensing due to its high sensitivity and low background *** there is a growing interest in near-infrared(NIR)chemiluminescent probes for improved tissue penetration and reduced *** review summarizes NIR emissive chemiluminescent probes based on 1,2-dioxetane and discusses their chemical structures and *** modification strategies for red-shifting wavelength and enhancing brightness include incorporating electron-withdrawing groups,designing chemiluminophore-fluorophore cassettes,and exploring alternative chemiluminescent *** review aims to inspire the exploration of NIR chemiluminescent probes in disease detection and treatment.

关键词： Chemiluminescence Near-infrared Dioxetane Bioimaging Biosensing