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Mercury Levels Assessment in the Population of Aby and Frambo Villages in the Vinicity of Aby Lagoon in Côte d’Ivoire (West Africa)

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Journal of Water Resource and Protection 2024年第3期16卷 219-232页

作者： Stéphane Jean Claon Serge Kouakou Kouassi nina Laurette Ahouéfa Laurent Kipré Seri Arsène M’bassidjé Seka Joseph Allico djaman Luc Kouakou Kouadio Analytical Sciences and Public Health department University of Félix Houphou&eumlt-Boigny Abidjan C&ocircte d'Ivoire Water Quality Control and Analysis Laboratory (LACQUE) Office National de l’Eau Potable (ONEP) Abidjan C&ocircte d’Ivoire Biology and Health Laboratory University of Félix Houphou&eumlt-Boigny Abidjan C&ocircte d’Ivoire Laboratory of Nutrition and Food Safety Department of Science and Food Technology Nangui Abrogoua University Abidjan C&ocircte d'Ivoire department of Medical and Fundamental Biochemistry Institut Pasteur of C&ocircte d'Ivoire Abidjan C&ocircte d’Ivoire Laboratory of Environmental Sciences (LSE) University of Nangui Abrogoua Abidjan C&ocircte d’Ivoire

The Minamata Convention in the aim to protect human life and the environment, seeks to reduce mercury (Hg) by monitoring it concentrations in the environment. Artisanal and Small-scale Gold Mining (ASGM) has been identified as the most important anthropogenic source of human exposure to Hg. In this context, the main goal of this study was to assess the level of mercury in hair of two (2) populations living along two lagoons respectively Aby and Tendo, in Ivory Coast. To reach this goal, hair samples of 138 residents were collected and analyzed by using Cold Vapor Atomic Fluorescence Spectrophotometry (CV-AFS) technique for mercury concentration. Results showed that for the entire population the Hg mean was 2.34 μg/g. Also, they were ranged between 0.15 to 8.53 μg/g and presented substantial differences amongst the villages. In Aby village, we observed the highest Hg concentrations (Mean = 2.62 μg/g). Our findings showed that almost the entire sample group (82%) exceed the USEPA recommended limit, furthermore 56% of them exceed the normal level of WHO and 2% of the respondent has the unhealthy levels of mercury (≥6 μg Hg/g) of hair by WHO standards. Gender differences in hair mercury varies greatly among reports. Lower levels in women’s hair compared to men were reported in the both village. Considering age, the lowest concentrations were observed with children. However, when we take in account the age groups, data suggested that the most exposed sub-population of [18-29] years old is from Aby village in opposite at Frambo village, the same case those who were ≥ 40 years old. It’s convenient to note that, the proportion of Mercury levels would not to be neglected among studied population especially with the resident from Aby village. So, some measures need to be taken at the political level to control mercury contamination.

关键词： Mercury Hair ASGM Population Exposure Côte d’Ivoire

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Azoospermia:vasal agenesis

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Asian Journal of Andrology 2022年第1期24卷 1-4页

作者： J Sam fisher Edward d Kim department of Urology University of TennesseeKnoxvilleTN 37920USA

SPECIFIC GENETIC TESTS(CFTR ANd INTRON 8 SPLICE VARIANT TESTING)ANd THEIR SIGNIFICANCE Congenital bilateral absence of the vas deferens(CBAVd)and cystic fibrosis(CF)began as separate entities with an apparent clinical *** occurs in 1%–2%of men presenting with infertility at urological departments and has an incidence of 1:1000–1:2000 in Caucasian *** example of this anatomic variant is shown in Figure 1.

关键词： correlation. clinical Figure

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Epidemiological, Clinical and Paraclinical Profile of Osteoarthritis of the Lower Limbs in Obese Patients at the Cocody University Teaching Hospital

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Open Journal of Rheumatology and Autoimmune diseases 2024年第2期14卷 69-76页

作者： Nzima Brice Kollo Aboubakar Bamba¹ Aboubacar Sidiki Condé Nzima Hilary Ngon Kanbaye Medom Ada nina Kpami Yaya Coulibaly Kan Joseph Enoch Koffi Ehaulier Soh Christian Louis Kouakou Mohamed diomandé¹ Edmond Eti Rheumatology department Cocody University Hospital Abidjan C&#244te d&#8217Ivoire Internal Medicine department Yaounde University Hospital Yaounde Cameroon Rheumatology department Bouake University Hospital Bouake C&#244te d&#8217Ivoire

Objective: To describe the epidemiological, clinical and paraclinical characteristics of osteoarthritis of the lower limbs in obese patients at the Cocody University Teaching Hospital. Methodology: This was an analytical cross-sectional study carried out in the rheumatology department of the Cocody UTH in Abidjan (Ivory Coast) from March 1 to April 30 2023. Patients who came for rheumatology consultation presenting with mechanical arthralgia of the lower limbs, who were obese, had radiographic images were included. All patients without radiographic images were excluded. Obesity was defined as a body mass index (BMI) greater than or equal to 30 kg/m. The Chi2 test was used to compare proportions and determine the existence of associations between osteoarthristis and obesity, obesity severity and radiographic stage of osteoarthritis as well as the functional impact. A p-value below a predefined threshold (p = 0,05) indicates a significant relationship between the variables. Result: Out of 185 patients received for osteoarthritis of the lower limbs during the study period, 136 were obese (74%). There were 115 women (84.6%) with an average age of 56.03 with a standard deviation of 12.72 years (extremes: 22 and 84 years). The main socio-professional category was the informal sector (30%). The majority of patients had a low socio-economic level (80.2%) and lived in urban areas (92.6%). The most common past medical history was hypertension (33.08%) followed by peptic ulcer disease (16.91%). Patients had a body mass index class 1 (81.6%), class 2 (15.40%) and class 3 (2.90%). The average duration of symptom progression until diagnosis was 11 months. Genu varum was the main static disorder (56.10%) and the knee joint was the dominant topography (90.4%) with a bilateral localization (80%). The average Lequesne index was greater than 8 (59.5%). The Kellgren and Lawrence radiographic stages were stage 1 (9.20%), stage 2 (46.90%), stage 3 (29.20%) and stage 4 (6.90%).

关键词： Osteoarthritis Lower Limbs Obesity Abidjan

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鼻咽癌放化疗患者营养状态及其与癌因性疲乏的相关性研究

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生命科学仪器 2024年第4期22卷 65-67页

作者：蔡妮娜罗洁华中科技大学同济医学院附属同济医院肿瘤科

目的观察分析鼻咽癌放疗患者营养状态及其与癌因性疲乏的相关性。方法选取2022年3月至2023年3月华中科技大学同济医学院附属同济医院收治的88例鼻咽癌患者，在放疗期间前1 d(T1)及放疗第15次(T2)、放疗第30次(T3)、放疗结束后(T4),采... 详细信息

目的观察分析鼻咽癌放疗患者营养状态及其与癌因性疲乏的相关性。方法选取2022年3月至2023年3月华中科技大学同济医学院附属同济医院收治的88例鼻咽癌患者，在放疗期间前1 d(T1)及放疗第15次(T2)、放疗第30次(T3)、放疗结束后(T4),采用营养风险评估表(NRS2002)及癌因性疲乏量表(CRF)评估其营养状态、癌因性疲乏情况，检测营养相关生化指标。结果鼻咽癌放化疗患者在治疗过程中不同时间点的血清白蛋白、前白蛋白、淋巴细胞、血红蛋白对比，P<0.05,且较治疗前均降低；鼻咽癌放化疗患者治疗后营养不良率为28.4%、52.27%、73.86%、98.86%,呈上升趋势，P<0.05;治疗后，鼻咽癌放化疗患者各时间点CRF量表评分呈上升趋势，P<0.05;鼻咽癌放化疗患者各时间点NRS评分与CRF维度评分及总分均呈正相关性，P<0.05。结论鼻咽癌患者放化疗期间营养不良风险比例偏高，变化趋势呈上升状，其营养状态与癌因性疲乏相关，需积极给予营养支持，以降低癌因性疲乏程度。

关键词：鼻咽癌癌因性疲乏营养状态化疗

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New fossil mayflies （Insecta： Ephemeroptera） from the Middle Jurassic of daohugou, Inner Mongolia, China

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Insect Science 2008年第2期15卷 193-198页

作者： Jian-dong Huang dong Ren nina d. Sinitshenkova Chung-Kun Shih College of Life Science Capital Normal University Beijing China Palaeontological Institute of the Russian Academy of Sciences MoscowRussia

Abstract Jurassonurus amoenus, a new genus and species of Siphlonuridae s. I. is described from the Middle Jurassic Jiulongshan Formation of the daohugou Village, Shantou Township, Ningcheng County, Inner Mongolia, China. The new species is estab- lished by more than 20 imago and subimago specimens in relatively good condition. detailed description and illustration of the specimens along with a review of fossil Siphlonuridae s. I. are given. Comparing with two known dominant nymph species Fuyous gregarious Zhang and Kluge, 2007 and Shantous lacustri Zhang and Kluge, 2007 from the same locality, we could not find any relationship among them. The new species is another dominant species in daohugou beds.

关键词： new genus new species Ephemeroptera Siphlonuridae fossil daohugou,Middle Jurassic China

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Three New Stoneflies (Insecta:Plecoptera) from the Yixian Formation of Liaoning,China

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Acta Geologica Sinica(English Edition) 2008年第2期82卷 249-256页

作者： LIU Yushuang REN dong nina d. SINITSHENKOVA SHIH Chungkun College of Life Sciences Capital Normal University Beijing 100037 China Paleontological Institute of the Russian Academy of Sciences Profsoyuznaya 123 Moscow Russia

Three new genera and species Archaeoperla rarissimus gen. et sp. nov. （Perlidae）, Liaotaenionema tenuitibia gen. et sp. nov. （Taeniopterygidae） and Parvinemoura parvus gen. et sp. nov. （？Nemouridae） are described and illustrated. All of them were collected from Yixian Formation of the western Liaoning, China. Hitherto, A. rarissimus is the oldest species possessing typical characters of Perlidae; the finding of L. tenuitibia indicates taeniopterygids once lived in the northeastern China in the late Mesozoic, but frequent volcanic activities, climate changes, or other environmental changes might have resulted in the disappearance of Taeniopterygidae in northern China after Mesozoic. Ancestral groups of Nemouridae have been abundant from Middle Jurassic, and male genitalia of P. parvus gen. et sp. nov. has been developed and similar to extant Nemouridae in the late Mesozoic. The stonefly fossils found from Yixian Formation are not divers at the species level, but rich at the family level. The diversity of stonefly implies different microclimate existed in the northeastern China at that time. A large old lacustrine basin existed in the western Liaoning, surrounded by hygrophilous plants on swampland and lake shore, warm and humid; tall arbor and boscage on the hillside nearby, mild and dry; mountains in the distance, rivulets running among the mountains, cool and wet. Many insects, prefer cool climate （e.g. stonefly, raphidiopterans, et ai.）, lived in the mountains with rivulets.

关键词： Plecoptera Huangbanjigou dawangzhangzi Yixian Formation Liaoning

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Liver fat content determined by magnetic resonance imaging and spectroscopy

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World Journal of Gastroenterology 2010年第13期16卷 1560-1566页

作者： Fabian Springer Jürgen Machann Claus d Claussen Fritz Schick nina F Schwenzer Section on Experimental Radiology Department of Diagnostic and Interventional Radiology University Hospital Tübingen department of diagnostic and Intervent ional Radiology University Hospital Tübingen

Hepatic steatosis as the most prevalent liver disorder can either be related to alcoholic liver disease (ALd) or non-alcoholic fatty liver disease (NAFLd). In both conditions, hepatocytes excessively accumulate fatcontaining vacuoles within their cytoplasm, which is the key histological feature. In contrast to ALd, NAFLd is commonly associated with metabolic syndrome, obesity and insulin resistance. To determine increased liver fat content, liver biopsy is currently considered the gold standard. Besides the invasive technique, various other non-invasive techniques have been developed, such as ultrasound, computed tomography (CT), magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) based methods. Among these techniques, ultrasound and CT provide only qualitative information about hepatic steatosis, whereas MRS-or MRI-based methods are able to determine even small amounts of fat accurately. These non-invasive magnetic resonance techniques have already proven their great potential, especially in longitudinal and cross-sectional studies regarding various metabolic conditions and medical treatment regimens. In this review, the most common, non-invasive MRS/MRI techniques for assessment of intrahepatic lipid content are described with their inherent advantages and limitations.

关键词： Hepatic steatosis Magnetic resonance imaging Proton magnetic resonance spectroscopy Lipids

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Manipulation of the intestinal microbiome-a slow journey to primetime

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World Journal of Clinical Cases 2023年第21期11卷 4975-4988页

作者： Ofra Kriger-Sharabi Stephen d H Malnick david.fisher Institute of Gastroenterology Assuta Medical CenterAshdod 7747629Israel department of Internal Medicine Kaplan Medical CenterRehovot 76100Israel department of Endocrinology Soroka Medical CenterBeer Sheva POB 151Israel

The gut microbiota has important functions in the regulation of normal body *** of the microbiota are being increasingly linked to various disease *** microbiome has been manipulated via the administration of stool from animals or humans,for more than 1000 ***,fecal microbiota transplantation can be performed via endoscopic administration of fecal matter to the duodenum or colon or via capsules of lyophilized *** recently fecal microbial transplantation has been shown to be very effective for recurrent Clostridoides difficile infection(CdI).In addition there is some evidence of efficacy in the metabolic syndrome and its hepatic manifestation,metabolic associated fatty liver disease(MAFLd),irritable bowel syndrome(IBS)and inflammatory bowel disease(IBd).We review the current literature regarding the microbiome and the pathogenesis and treatment of CdI,MAFLd,IBS and IBd.

关键词： Gut microbiota Fecal microbiota transplantation Clostridoides difficile Metabolic associated fatty liver disease Irritable bowel syndrome Inflammatory bowel disease

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Broccoli sprouts juice prevents lens protein aggregation in streptozotocin-induced diabetic rat

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International Journal of Ophthalmology(English edition) 2019年第9期12卷 1380-1385页

作者： Ayu Puspitasari nina Handayani department of Ophthalmology Faculty of Medicine Universitas Brawijaya Dr. Saiful Anwar General Hospital

AIM: To investigate the effect of broccoli sprouts juice in preventing lens protein aggregation in diabetic rat ***: Totally 25 male Wistar rats were divided into negative control group, diabetic group without juice treatment as positive control and diabetic group given broccoli sprouts juice 0.25, 0.5 and 1 g/d for 28 d. diabetic rat model was obtained by administering a single dose streptozotocin 65 mg/kg intraperitoneal. At the end of the study, all rats were examined for fasting blood sugar level(FBS), visual cataract score using slit lamp biomicroscope and lens αB-crystallin expression using Western blot method. Statistical analysis was performed using one way ANOVA with post hoc test, correlation test, and simple linear ***: Positive control group had the highest cataract score and lens aggregated αB-crystallin expression. Broccoli sprout juice dose of 1 g/d group had the mildest cataract score, as well as the expression of lens aggregated αB-crystallin compared to treatments groups 1 and 2, opposite to lens native αB-crystallin expression. The broccoli sprout juice groups gave a significant decrease in cataract score, and also in lens aggregated αB-crystallin expression in diabetic rat models(Pdiabetic rat model. The higher dose gives better visual cataract scores, lower lens aggregated αB-crystallin expression and higher lens native αB-crystallin expression.

关键词： diabetic cataract broccoli sprouts oxidative stress lens αB-crystallin rat

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Host preference of the major strains of Plum pox virus--Opinions based on regional and world-wide sequence data

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Journal of Integrative Agriculture 2017年第3期16卷 510-515页

作者： nina Sihelská Miroslav Glasa Zdeno W Subr Biomedical Research Center Institute of Virology Slovak Academy of Sciences Bratislava 84505 Slovak Republic

Plum pox virus（PPV）causes sharka-the most serious viral disease of stone fruit *** is wide spread in Europe and Mediterranean Basin,its incidence has been further approved in Asia and both *** PPV strains have been recognized until now（PPV-d,PPV-M,PPV-Rec,PPV-EA,PPV-C,PPV-T,PPV-W,PPV-CR,and PPV-An）,forming molecularly distinct entities,however,only partially differentiable by their biological or epidemiological *** most strict virus-host linkages under natural conditions have been detected for strains naturally infecting cherries（PPV-C and PPV-CR）.However,although less stringent but still clear host preference is observed also for three epidemiologically most important strains（PPV-d/plum/apricot,PPV-M/peach,and PPV-Rec/plum）.So far no genetic marker has been mapped in the PPV genome,which responsibility for the host specificity/preference could be explicitly *** this review,we focus on the host preference of three major PPV strains as evidenced by analysis of an extensive dataset of PPV isolates of Slovak and world-wide ***,we discuss several performed relevant experiments and further possible research procedures aimed to better understand the genetic determinants and mechanisms of the host preference of this potyvirus.

关键词： sharka Prunus virus-host interactions

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