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Nano-to micro-pore characterization by synchrotron radiation SAXS and nano-CT for bituminous coals

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Frontiers of Earth Science 2021年第2期15卷 189-201页

作者： Yixin ZHAO Chujian HAN Yingfeng SUN nima Noraei DANESH Tong LIU Yirui GAO Beijing Key Laboratory for Precise Mining of Intergrown Energy and Resources China University of Mining and Technology(Beijing)Beijing 100083China School of Energy and Mining Engineering China University of Mining and Technology(Beijing)Beijing 100083China School of Civil and Resource Engineering University of Science and Technology BeijingBeijing 100083China Key Laboratory of Deep Earth Science and Engineering(Ministry of Education) Sichuan UniversityChengdu 610065China

Considering the complementarity of synchrotron radiation SAXS and nano-CT in the pore structure detection range,synchrotron radiation SAXS and nano-CT methods were combined to characterize the nano-to micropore structure of two bituminous coal *** mesopores,the pore size distribution curves exhibit unimodal distribution and the average pore diameters are similar due to the affinity of metamorphic grades of the two *** macropores,the sample with higher mineral matter content,especially clay mineral content,has a much higher number of *** fractal dimensions representing the pore surface irregularity and the pore structure heterogeneity were also characterized by synchrotron radiation SAXS and *** fractal dimensions estimated by both methods for different pore sizes show consistency and the sample with smaller average pore diameters has a more complex pore structure within the full tested range.

关键词： synchrotron radiation SAXS nano-CT pore size distribution fractal coal

Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease

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World Journal of Gastroenterology 2017年第47期23卷 8300-8307页

作者： nezha Senhaji Sellama Nadifi Younes Zaid Aurora Serrano Daniel Arturo Leon Rodriguez Nadia Serbati Mehdi Karkouri Wafaa Badre Javier Martín Laboratory of Genetic and Molecular Pathology Faculty of Medicine and Pharmacy of CasablancaHassanⅡUniversity Mohammed VI University of Health Sciences Instituto de Parasitología y Biomedicina López-Neyra Consejo Superior de Investigaciones Científicas Department of Pathology CHU Ibn Rochd Department of Gastroenterology CHU Ibn Rochd

AIM To investigate whether common variants in the oxidative pathway genes influence inflammatory bowel disease(IBD) risk among Moroccan patients. METHODS The distribution of(TAAA)n_rs12720460 and(CCTTT)n_rs3833912 NOS2 A microsatellite repeats, HIF-1 A_rs11549467 and NFKB1-94 ins/delA TTG_rs28362491 was analyzed in 507 subjects grouped in 199 IBD and 308 healthy controls. Genotyping was performed withpolymerase chain reaction-fluorescent method and the TaqMan~? allelic discrimination *** The allele and genotype frequencies of HIF1 A_ rs11549467, NFKB1_rs28362491 and NOS2 A_(TAAA)n did not differ significantly between patients and controls. Analysis of NOS2 A_(CCTTT)n markers evidenced differences between patients and healthy controls. A preferential presence of the(CCTTT)8(P = 0.02; OR = 1.71, 95%CI: 1.07-2.74),(CCTTT)14(P = 0.02; OR = 1.71, 95%CI: 1.06-2.76) alleles in IBD,(CCTTT)8(P = 0.008; OR = 1.95, 95%CI: 1.17-3.23) in CD and(CCTTT)7(P = 0.009; OR = 7.61, 95%CI: 1.25-46.08),(CCTTT)11(P = 0.05; OR = 0.51, 95%CI: 0.25-1.01),(CCTTT)14(P = 0.02; OR = 2.05, 95%CI: 1.07-3.94),(CCTTT)15(P = 0.01; OR = 2.25, 95%CI: 1.16-4.35) repeats in UC patients indicated its possible association with higher disease risk which need to be confirmed in a larger sample size. CONCLUSION Our results suggest that the NOS2 A_(CCTTT)n gene variations may influence IBD susceptibility in the Moroccan population.

关键词： HIF1A NFKB1 NOS2A Inflammatory bowel disease Moroccan patients

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西藏高速公路气象灾害预警服务研究

高原科学研究 2024年第1期8卷 49-56页

作者：德庆卓嘎尼玛卓嘎次仁次仁曲宗西藏高原大气环境科学研究所/西藏高原大气环境开放实验室西藏拉萨850000 西藏大学生态环境学院西藏拉萨850000 西藏自治区气象服务中心西藏拉萨850000

文章基于2018—2019年西藏自治区气象和交通部门联合开展的西藏高速公路气象灾害风险隐患点普查数据,分析了西藏高速公路气象灾害隐患点的空间分布特征。结果表明,西藏高速公路风险隐患点分布广泛,总体呈东多西少,南多北少的特点;主要... 详细信息

文章基于2018—2019年西藏自治区气象和交通部门联合开展的西藏高速公路气象灾害风险隐患点普查数据,分析了西藏高速公路气象灾害隐患点的空间分布特征。结果表明,西藏高速公路风险隐患点分布广泛,总体呈东多西少,南多北少的特点;主要的风险隐患点集中在拉萨至林芝路段、泽当至拉萨路段;风险隐患点的路基岩土类型以碎石土为主,风险隐患点与植被覆盖率有一定的关联性;影响西藏高速公路主要气象灾害风险依次为路面结冰、强降雪、强降雨、大风,尤其林芝段大部分路段为高架桥,冬季易结冰,风险较大。据此,文章提出了一套适合西藏高速公路气象灾害预警服务方法,即综合考虑沿线地形、地理信息、灾害风险类型等多种影响因子,结合现有的中尺度预报模式及前端预报产品,获得影响西藏高速公路交通的关键气象要素、区域特征和重点季节,进而划分不同区域不同等级高影响天气风险指标,并根据西藏公路交通具体情况进行订正,形成了逐3 h、6 h或24 h发布的未来7 d西藏高速公路气象灾害预警风险评估服务产品。

关键词：西藏高速公路灾害性天气预报服务

Consolidation of soft clay foundation improved by geosyntheticreinforced granular columns:Numerical evaluation

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Journal of Rock Mechanics and Geotechnical Engineering 2021年第5期13卷 1173-1181页

作者： nima R.Alkhorshid Gregório L.S.Araujo Ennio M.Palmeira Institute of Integrated Engineering Federal University of Itajubáe Itabira CampusItabiraMinas Gerais35903-087Brazil Department of Civil and Environmental Engineering University of BrasíliaBrasíliaDistrito Federal70910-900Brazil

Soft clays are problematic soils as they present high compressibility and low shear *** are several methods for improving in situ conditions of soft *** on the geotechnical problem’s geometry and characteristics,the in situ conditions may require reinforcement to restrain instability and construction *** columns reinforced by geosynthetic material are widely used to reduce settlements of embankments on soft *** also accelerate the consolidation rate by reducing the drainage path’s length and increasing the foundation soil’s bearing *** this study,the performance of encased and layered granular columns in soft clay is investigated and *** numerical results show the significance of geosynthetic stiffness and the column length on the embankment ***,the results show that granular columns may play an important role in dissipating the excess pore water pressures and accelerating the consolidation settlements of embankments on soft clays.

关键词： Geosynthetic Embankment Granular column Consolidation Soft soil

‘藏农薯1号’不同级别种薯的病毒种类及生物学性状比较

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中国马铃薯 2024年第2期38卷 151-159页

作者：许娟妮尼玛卓嘎曾钰婷祁驰恒西藏自治区农牧科学院蔬菜研究所西藏拉萨850000

种薯退化是制约马铃薯(Solanum tuberosum L.)产业发展的重要因素,不同级别种薯播种后在田间发病情况通常差异较大,进而影响其生物学性状及经济效益。以西藏自治区选育品种‘藏农薯1号’为试验材料,分析各级种薯(原原种、原种、一级种... 详细信息

种薯退化是制约马铃薯(Solanum tuberosum L.)产业发展的重要因素,不同级别种薯播种后在田间发病情况通常差异较大,进而影响其生物学性状及经济效益。以西藏自治区选育品种‘藏农薯1号’为试验材料,分析各级种薯(原原种、原种、一级种、二级种)在田间病毒再侵染情况,比较各级种薯植株生长发育、块茎品质和产量等生物学特性。原原种植株中仅检测到马铃薯S病毒,其他级别种薯植株中可检测到马铃薯卷叶病毒和S病毒。同时,原原种植株田间马铃薯卷叶病毒和S病毒病发病率和病情指数均较低,二级种则相反。在生长发育过程中,现蕾期叶片的叶绿素含量和光合速率最高;随着种薯级别降低,叶绿素含量和光合速率呈下降趋势,而株高差异小。不同级别种薯块茎淀粉和干物质含量差异小,还原糖含量随着种薯级别降低而降低。产量和商品薯率统计结果显示,原原种最高、二级种最低,而原种和一级种之间未见显著差异。考虑到种薯成本和经济效益,在‘藏农薯1号’马铃薯生产中,种薯应优先选用原种和一级种。

关键词：种薯级别病毒生长特性产量

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《自然语言处理》课程教学模式改革与探索——以西藏大学为例

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高原科学研究 2024年第3期8卷 125-132页

作者：群诺格勒尼玛曹玺达瓦追玛洛桑嘎登西藏大学信息科学技术学院西藏拉萨850000 西藏信息化省部共建协同创新中心西藏拉萨850000 中央民族大学哲学与宗教学学院北京100081

文章对目前我国高等院校积极开设的《自然语言处理》课程进行了研究分析,结合西藏大学计算机科学与技术专业研究生课程体系结构和自身服务民族地区信息化建设的特点,提出了教学内容、教学方法和考核方式等课程建设方面的新认识和新观点... 详细信息

文章对目前我国高等院校积极开设的《自然语言处理》课程进行了研究分析,结合西藏大学计算机科学与技术专业研究生课程体系结构和自身服务民族地区信息化建设的特点,提出了教学内容、教学方法和考核方式等课程建设方面的新认识和新观点。文章认为《自然语言处理》课程的教学模式改革应当从优化教学内容、创新教学模式、整合教学资源、加强实践能力等方面着手,以培养研究生的理论水平、实践能力和创新思维为目标,推动自然语言处理技术和教育的可持续发展。

关键词：《自然语言处理》课程教学模式课程建设西藏大学

Gelatin-based hydrogel functionalized with taurinemoieties for in vivo skin tissue regeneration

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Bio-Design and Manufacturing 2023年第3期6卷 284-297页

作者： Farnaz Rahimi nima Ahmadkhani Aida Goodarzi Fariba Noori Sajad Hassanzadeh Sepideh Saghati Mehdi Khanmohammadi Arash Goodarzi Department of Tissue Engineering School of Advanced Technologies in MedicineFasa University of Medical ScienceFasaIran School of Chemical Biological and Environmental EngineeringOregon State UniversityCorvallisOR 97331USA Eye Research Center School of MedicineThe Five Senses Health InstituteIran University of Medical SciencesTehranIran Skull Base Research Center School of MedicineThe Five Senses Health InstituteIran University of Medical SciencesTehranIran Department of Tissue Engineering Faculty of Advanced Medical SciencesTabriz University of Medical SciencesTabrizIran

Functionalized hydrogels stimulate the migration and morphogenesis of endothelial cells(ECs)and are useful substrates for wound *** present study investigates the feasibility of covalent conjugation of taurine(Tau)on a gelatin-based *** hydrogel is expected to maintain positive charged growth factors such as basic fibroblast growth factor(bFGF)and vascular endothelial growth factors(VEGFs)near ECs within the hydrogel *** gelatin was conjugated with hydroxyl phenol(Ph)and Tau moieties,and in following that Ph residues were crosslinked through a horseradish peroxidase-catalyzed *** migration characteristics of ECs were analyzed by scratch migration assay and microparticle-based cell migration *** morphology and amounts of angiopoietin 1(Ang 1),bFGF,and VEGF proteins were evaluated for encapsulated *** potential of synthesized hydrogels in wound healing was assessed by the percentage of reduction from the original wound size and histopathological analyses of rat *** incorporated Tau molecules within the hydrogel remained stable through covalent bonds during *** extended incubation,the gelatin-based hydrogel conjugated with Tau improved the migration distance and number of existing migrated *** Tau within the gelatin-based hydrogel induced high motility of ECs,accompanied by robust cytoskeleton extension and a cell subpopulation that expressed CD44 and CD31 receptors as well as enhancement of Ang 1,bFGF,and *** found that injectable Gel-Ph-Tau effectively improves wound-healing parameters.

关键词： Taurine conjugation Covalent crosslinking Immobilization of growth factors Gelatin-based hydrogel Endothelial cells

Female anterior wall onlay urethroplasty with lower lip buccal mucosal graft: Importance of the laterally extended incision

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Asian Journal of Urology 2023年第1期10卷 33-38页

作者： Maryam Emami Pejman Shadpour Koosha Kamali nima Narimani Jalil Hosseini Hasheminejad Kidney Center Iran University of Medical SciencesTehranIran Hasheminejad Kidney Center(HKC) Hospital Management Research CenterIran University of Medical SciencesTehranIran Hasheminejad Kidney Center(HKC) Iran University of Medical SciencesTehranIran Men’s Health and Reproductive Health Research Center Shahid Beheshti University of Medical SciencesTehranIran

Objective:To describe the outcome of female anterior wall(pubic side)onlay urethroplasty with buccal mucosal graft using laterally extended surgical dissection in patients with previously failed minimally invasive ***:From January 2016 to April 2018,17 symptomatic patients with previously failed minimally invasive procedures were enrolled in the *** diagnosis of urethral stricture was confirmed based on a combination of patients’symptoms,post-void residual urine,video-urodynamics,and *** with lower lip mucosal graft was performed using the modified laterally extended *** were evaluated pre-operatively and 12-month post-operatively with the American Urological Association symptom score,post-void residual urine,and maximum flow ***:Despite the previously failed minimally invasive procedures,urethroplasty with lower lip buccal graft and laterally extended dissection resulted in favorable outcomes(success rateZ94%).The meanstandard deviation of American urological association symptom score improved from pre-operative levels at the 12-month post-operative follow-up(25.823.97 to 10.885.57);so did postvoid residual urine(71.1274.98 mL to 15.0028.30 mL),and maximum flow rate(7.881.72 mL/s to 25.825.59 mL/s)with all statistically significant(p<0.05).Conclusion:The current study showed that female urethroplasty with buccal graft could be highly successful in experienced *** anterior approach could be superior to the posterior one due to higher mechanical support and lower sacculation rate.A laterally extended incision may improve visualization and better graft placement by providing wider working *** results should be evaluated in the future studies with larger sample size.

关键词： Female urethroplasty Buccal graft Dorsal Anterior wall onlay Urethral stricture Video-urodynamics

Speed profile optimization of catenary-free electric trains with lithium-ion batteries

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Journal of Modern Transportation 2019年第3期27卷 153-168页

作者： nima Ghaviha Markus Bohlin Christer Holmberg Erik Dahlquist Malardalen University Hogskoleplan 1 72220 Vasteras Sweden RISE SICS Vasteras AB Stora Gatan 36 72212 Vasteras Sweden Bombardier Transportation Ostra Ringvagen 2 72214 Vasteras Sweden

Catenary-free operated electric trains, as one of the recent technologies in railway transportation, has opened a new field of research: speed profile optimization and energy optimal operation of catenary-free operated electric trains. A well-formulated solution for this problem should consider the characteristics of the energy storage device using validated models and methods. This paper discusses the consideration of the lithium-ion battery behavior in the problem of speed profile optimization of catenary-free operated electric trains. We combine the single mass point train model with an electrical battery model and apply a dynamic programming approach to minimize the charge taken from the battery during the catenary-free operation. The models and the method are validated and evaluated against experimental data gathered from the test runs of an actual battery-driven train tested in Essex, UK. The results show a significant potential in energy saving. Moreover, we show that the optimum speed profiles generated using our approach consume less charge from the battery compared to the previous approaches.

关键词： Electric train Catenary-free operation Speed profile optimization Energy efficiency