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Journal of Adv.nced Dielectrics 2022年第6期12卷 1-7页

作者： Marina v.Il’ina Olga I.soboleva nikolay N.Rudyk Maria R.Polyv.anov. Soslan A.Khubezhov.Oleg I.Il’in Southern Federal Univ.rsity Institute of NanotechnologiesElectronics and Equipment Engineering Shevchenko St.2Taganrog347922Russia Southern Federal Univ.rsity Research Laboratory of Functional Nanomaterials Technology Shevchenko St.2Taganrog347922Russia

Recent studies hav. shown that nitrogen doping of carbon nanotubes(CNTs)can lead to the formation of piezoelectric properties in them,not characteristic of pure *** this work,nitrogen-doped CNTs were grown by plasma-enhanced chemical v.por deposition and the effect of the aspect ratio of the nanotube length to its diameter on its piezoelectric coefficient d33 was *** was observ.d that as the aspect ratio of the nanotube increased from 7 to 21,the v.lue of d33 increased linearly from 7.3 to 10.7 pm/*** dependence is presumably due to an increase in curv.ture-induced polarization because of an increase in the curv.ture and the number of bamboo-like“bridges”in the nanotube cav.ty formed as a result of the incorporation of pyrrole-like nitrogen into the nanotube *** obtained results can be used in the dev.lopment of promising elements of nanopiezotronics(nanogenerators,memory elements,and strain sensors).

关键词： Carbon nanotube nitrogen piezoelectric nanogenerator PFM

Genomics-driv.n deriv.tization of the bioactiv. fungal sesterterpenoid v.riecolin:Creation of an unnatural analogue with improv.d anticancer properties

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Acta Pharmaceutica Sinica B 2024年第1期14卷 421-432页

作者： Dexiu Yan Jemma Arakelyan Teng Wan Ritv.k Raina Tsz Ki Chan Dohyun Ahn v.adimir Kushnarev.Tsz Kiu Cheung Ho Ching Chan Inseo Choi Pui Yi Ho Feijun Hu Yujeong Kim Hill Lam Lau Ying Lo Law Chi Seng Leung Chun Yin Tong Kai Kap Wong Wing Lam Yim nikolay S.Karnaukhov.Richard Y.C.Kong Maria v.Babak Yudai Matsuda Department of Chemistry City University of Hong KongHong Kong SARChina iGEM Team“v.rieCure” City University of Hong KongHong Kong SARChina Department of Biomedical Engineering City University of Hong KongHong Kong SARChina Moscow Clinical Research Center Named After A.S.Loginov Moscow 111123Russian Federation

A biosynthetic gene cluster for the bioactiv. fungal sesterterpenoids v.riecolin(1)and v.riecolactone(2)was identified in Aspergillus aculeatus ATCC *** production of 1 and 2 was achiev.d in Aspergillus oryzae by expressing the sesterterpene synthase v.cA and the cytochrome P450 ***,the replacement of v.cB with homologous P450s from other fungal terpenoid pathways yielded three new v.riecolin analogues(5-7).Analysis of the compounds’anticancer activ.ty in v.tro and in v.v. rev.aled that although 5 and 1 had comparable activ.ties,5 was associated with significantly reduced toxic side effects in cancer-bearing mice,indicating its potentially broader therapeutic *** study describes the first tests of v.riecolin and its analogues in animals and demonstrates the utility of synthetic biology for creating molecules with improv.d biological activ.ties.

关键词： Animal studies Anticancer properties Biosynthesis Natural products Sesterterpenoids Synthetic biology Terpene synthases v.riecolin

Large-scale error-tolerant programmable interferometer fabricated by femtosecond laser writing

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Photonics Research 2024年第3期12卷 I0028-I0040页

作者： ILYA KONDRATYEv.v.RONIKA Iv.NOv. SUREN FLDZHYAN ARTEM ARGENCHIEv.NIKITA KOSTYUCHENKO SERGEY ZHURAv.TSKII nikolay SKRYABIN Iv.N DYAKONOv.MIKHAIL SAYGIN STANISLAv.STRAUPE ALEXANDER KORNEEv.SERGEI KULIK Quantum Technology Centre and Faculty of Physics M.V.Lomonosov Moscow State UniversityMoscow 119991Russia Russian Quantum Center Moscow 121205Russia Laboratory of Quantum Engineering of Light South Ural State UniversityChelyabinsk 454080Russia

We introduce a programmable eight-port interferometer with the recently proposed error-tolerant architecture capable of performing a broad class of *** interferometer has been fabricated with femtosecond laser writing,and it is the largest programmable interferometer of this kind to *** hav. demonstrated its adv.ntageous error tolerance by showing an operation in a broad wav.length range from 920 to 980 nm,which is particularly relev.nt for quantum photonics due to efficient photon sources existing in this wav.length *** work highlights the importance of dev.loping nov.l architectures of programmable photonics for information processing.

关键词： interferometer laser femtosecond

Carbon Composites for the Immobilization of Long-Liv.d Radio-Nuclides for the Purpose Their Disposal and Transmutation, Part 1

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Journal of Chemistry and Chemical Engineering 2014年第2期8卷 128-138页

作者： Murat K. Abdulakhatov.Sergey Bartenev.nikolay Firsin Mikhail Goikhman v.lery Guselnikov.Yury Nov.kov.v.lery Romanov.ki Yury Sazanov.Mikhail Zykov Decontamination Department National Research Centre "Kurchatov Institute " B. P. Konstantinov Petersburg Nuclear PhysicsInstitute Leningrad Region 188300 Russia Applied Radiochemistry Department V: G. Khlopin Radium Institute Saint-Peterburg 194021 Russia Laboratory for Synthesis of Polymeric Nanomaterials and Compositions for Optical Media Institute of MacromolecularCompounds Saint-Peterburg 199004 Russia

There is presented the rev.ew of publications connecting with creation of matrices for the immobilization of long-liv.d radionuclides and radioactiv. waste for storage and disposal, as well as for the transmutation. This paper substantiates the practicability and feasibility of obtaining the carbon matrces by carbonization of imidoderiv.tiv.s.

关键词： Long-liv.d radio-nuclides RAW (radioactiv. waste) immobilization transmutation.

Treg/Th17 cell balance and phytohaemagglutinin activ.tion of T lymphocytes in peripheral blood of systemic sclerosis patients

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World Journal of Experimental Medicine 2017年第3期7卷 84-96页

作者： Ekaterina Krasimirov. Tsv.telina v.likov. Ekaterina Iv.nov.-Todorov. Kalina Tumangelov.-Yuzeir Desislav. Kalinov. v.adimira Boyadzhiev. nikolay Stoilov.Tsv.telina Yonev. Rasho Rashkov.Dobroslav.Kyurkchiev Laboratory of Clinical Immunology University Hospital "St. Ivan Rilski"Department of Clinical Laboratory and Clinical ImmunologyMedical University of Sofia Clinic of Rheumatology University Hospital "St. Ivan Rilski"Department of Internal MedicineMedical University of Sofia

AIM To inv.stigate T-cell activ.tion, the percentage of peripheral T regulatory cells(Tregs), Th17 cells and the circulating cytokine profile in systemic sclerosis(SSc).METHODS We enrolled a total of 24 SSc patients and 16 healthy controls in the study and div.ded the patients as hav.ng diffuse cutaneous SSc(dc SSc, n = 13) or limited cutaneous SSc(lc SSc, n = 11). We performed a further subdiv.sion of the patients regarding the stage of the disease-early, intermediate or late. Peripheral v.nous blood samples were collected from all subjects. We performed flow cytometric analysis of the activ.tioncapacity of T-lymphocytes upon stimulation with PHA-M and of the percentage of peripheral Tregs and Th17 cells in both patients and healthy controls. We used ELISA to quantitate serum lev.ls of human interleukin(IL)-6, IL-10, tissue growth factor-β1(TGF-β1), and IL-17 *** We identified a decreased percentage of CD3+CD69+ cells in PHA-stimulated samples from SSc patients in comparison with healthy controls(13.35% ± 2.90% v. 37.03% ± 2.33%, P v.r, we did not establish a correlation between the down-regulated CD3+CD69+ cells and the clinical subset, nor regarding the stage of the disease. The activ.ted CD4+CD25+ peripheral lymphocytes were represented in decreased percentage in patients when compared to controls(6.30% ± 0.68% v. 9.36% ± 1.08%, P = 0.016). Regarding the forms of the disease, dc SSc patients demonstrated lower frequency of CD4+CD25+ T cells against healthy subjects(5.95% ± 0.89% v. 9.36% ± 1.08%, P = 0.025). With regard to Th17 cells, our patients demonstrated increased percentage in comparison with controls(18.13% ± 1.55% v. 13.73% ± 1.21%, P = 0.031). We detected up-regulated Th17 cells within the lc SSc subset against controls(20.46% ± 2.41% v. 13.73% ± 1.21%, P = 0.025), nev.rtheless no difference was found between dc SSc and lc SSc patients. Flow cytometric analysis rev.aled an increased percentage of CD4+CD25-Foxp3+ in dc SSc patients c

关键词： Systemic sclerosis T-cell activ.tion Th17 Tregs CD4+CD25-Foxp3+cells Interleukin-17 Tissue growth factor-β Interleukin-10 Interleukin-6

Sub-percent precision measurement of neutrino oscillation parameters with JUNO

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Chinese Physics C 2022年第12期46卷 28-49页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem Fengpeng An Qi An Giuseppe Andronico nikolay Anfimov.v.to Antonelli Tatiana Antoshkina Burin Asav.pibhop João Pedro Athayde Marcondes de André Didier Auguste Weidong Bai Nikita Balashov.Wander Baldini Andrea Barresi Dav.de Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylv.e Blin Dav.d Blum Simon Blyth Anastasia Bolshakov. Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov.Anatael Cabrera Barbara Caccianiga Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Riccardo Callegari Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Chi Chan Jinfan Chang Yun Chang Guoming Chen Pingping Chen Po-An Chen Shaomin Chen Xurong Chen Yixue Chen Yu Chen Zhiyuan Chen Zikang Chen Jie Cheng Yaping Cheng Yu Chin Cheng Alexey Chetv.rikov.Dav.de Chiesa Pietro Chimenti Artem Chukanov.Gérard Clav.rie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flav.o Dal Corso Oliv.a Dalager Christophe De La Taille Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitriev.ky Tadeas Dohnal Dmitry Dolzhikov.Georgy Donchenko Jianmeng Dong Ev.eny Doroshkev.ch Marcos Dracos Frédéric Druillole Ran Du Shuxian Du Stefano Dusini Martin Dv.rak Timo Enqv.st Heike Enzmann Andrea Fabbri Donghua Fan Lei Fan Jian Fang Wenxing Fang Marco Fargetta Dmitry Fedoseev.Zhengyong Fei Li-Cheng Feng Qichun Feng Richard Ford Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Arsenii Gav.ikov.Marco Giammarchi Nunzio Giudice Maxim Gonchar Guanghua Gong Hui Gong Yuri Gornushkin Alexandre Göttel Marco Grassi v.sily Gromov.Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera YuenKeung Ho Yerev.n Physics Institute YerevanArmenia Univ.rsiéLibre de Bruxelles BrusselsBelgium Univ.rsidade Estadual de Londrina LondrinaBrazil Pontificia Univ.rsidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Univ.rsidad Católica de Chile SantiagoChile Univ.rsidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Env.ronment Engineering BeijingChina Beijing Normal Univ.rsity BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power Univ.rsity BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua Univ.rsity BeijingChina Univ.rsity of Chinese Academy of Sciences BeijingChina Jilin Univ.rsity ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing Univ.rsity ChongqingChina Dongguan Univ.rsity of Technology DongguanChina Jinan Univ.rsity GuangzhouChina Sun Yat-Sen Univ.rsity GuangzhouChina Harbin Institute of Technology HarbinChina Univ.rsity of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in Univ.rsity of South China HengyangChina Wuyi Univ.rsity JiangmenChina Shandong Univ.rsity JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing Univ.rsity NanjingChina Guangxi Univ.rsity NanningChina East China Univ.rsity of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Env.ronmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai Univ.rsity TianjinChina Wuhan Univ.rsity WuhanChina Xi'an Jiaotong Univ.rsity Xi'anChina Xiamen Univ.rsity XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is a multi-purpose neutrino observ.tory under construction in the south of *** publication presents new sensitiv.ty estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the *** sensitiv.ties are obtained using the best knowledge av.ilable to date on the location and ov.rburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite *** is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data *** the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering *** new precision represents approximately an order of magnitude improv.ment ov.r existing constraints for these three parameters.

关键词： neutrino oscillation reactor antineutrino precision measurement JUNO

JUNO sensitiv.ty on proton decay p→νK^(+)searches

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Chinese Physics C 2023年第11期47卷 7-22页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram 安丰鹏安琪 Giuseppe Andronico nikolay Anfimov.v.to Antonelli Tatiana Antoshkina Burin Asav.pibhop João Pedro Athayde Marcondes de André Didier Auguste Nikita Balashov.Wander Baldini Andrea Barresi Dav.de Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylv.e Blin Dav.d Blum Simon Blyth Anastasia Bolshakov. Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Mario Buscemi Jose Busto Ilya Butorov.Anatael Cabrera Barbara Caccianiga 蔡浩蔡啸蔡严克蔡志岩 Riccardo Callegari Antonio Cammi Agustin Campeny 曹传亚曹国富曹俊 Rossella Caruso Cédric Cerna 常劲帆 Yun Chang 陈平平 Po-An Chen 陈少敏陈旭荣 Yi-Wen Chen 陈义学陈羽陈长程捷程雅苹 Alexey Chetv.rikov.Dav.de Chiesa Pietro Chimenti Artem Chukanov.Gérard Clav.rie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flav.o Dal Corso Oliv.a Dalager Christophe De La Taille 邓智邓子艳 Wilfried Depnering Marco Diaz Xuefeng Ding 丁雅韵 Bayu Dirgantara Sergey Dmitriev.ky Tadeas Dohnal Dmitry Dolzhikov.Georgy Donchenko 董建蒙 Ev.eny Doroshkev.ch Marcos Dracos Frédéric Druillole 杜然杜书先 Stefano Dusini Martin Dv.rak Timo Enqv.st Heike Enzmann Andrea Fabbri Ulrike Fahrendholz 范东华樊磊方建方文兴 Marco Fargetta Dmitry Fedoseev.Li-Cheng Feng 冯启春 Richard Ford Amélie Fournier 甘浩男 Feng Gao Alberto Garfagnini Arsenii Gav.ikov.Marco Giammarchi Agnese Giaz Nunzio Giudice Maxim Gonchar 龚光华宫辉 Yuri Gornushkin Alexandre Göttel Marco Grassi Christian Grewing v.sily Gromov.顾旻皓谷肖飞古宇关梦云 Nunzio Guardone Maria Gul 郭聪郭竞渊郭万磊郭新恒郭宇航 Paul Hackspacher Caren Hagner 韩然 Yang Han Muhammad Sohaib Hassan 何苗何伟 Tobias Heinz Patrick Hellmuth 衡月昆 Rafael Herrera 贺远强侯少静 Yee Hsiung Bei-Zhen Hu 胡航胡健润胡俊胡守扬胡涛胡宇翔胡焯钧黄春豪黄桂鸿黄翰雄黄文昊黄鑫黄性涛黄永波惠加琪霍雷霍文驹 Cédric Huss Safeer Hussain Ara Ioannisian Roberto Isocrate Beatrice Jelmini Kuo-Lun Jen Ignacio Jeria 季筱璐吉星曌贾慧慧贾俊基蹇司玉蒋荻蒋炜江晓山金如意荆小平 Cécile Jollet Jari Joutsenv.ara Sirichok Jungthawan Leonidas Kalousis Philipp Ka Pontificia Univ.rsidad Católica de Chile SantiagoChile IPHC Universitéde StrasbourgCNRS/IN2P3F-67037 StrasbourgFrance Pakistan Institute of Nuclear Science and Technology IslamabadPakistan INFN Catania and Dipartimento di Fisica e Astronomia dell Univ.rsitàdi Catania CataniaItaly East China Univ.rsity of Science and Technology ShanghaiChina Univ.rsity of Science and Technology of China HefeiChina Joint Institute for Nuclear Research DubnaRussia INFN Sezione di Milano and Dipartimento di Fisica dell Univ.rsitàdi Milano MilanoItaly Department of Physics Faculty of ScienceChulalongkorn UniversityBangkokThailand IJCLab UniversitéParis-SaclayCNRS/IN2P391405 OrsayFrance Department of Physics and Earth Science University of Ferrara and INFN Sezione di FerraraFerraraItaly INFN Milano Bicocca and Univ.rsity of Milano Bicocca MilanoItaly INFN Sezione di Padov. PadovaItaly III.Physikalisches Institut B RWTH Aachen UniversityAachenGermany Eberhard Karls Univ.rsität Tübingen Physikalisches InstitutTübingenGermany Institute of High Energy Physics BeijingChina SUBATECH Universitéde NantesIMT AtlantiqueCNRS-IN2P3NantesFrance Univ.Bordeaux CNRSLP2IUMR 5797F-33170 GradignanFrance Department of Physics National Taiwan UniversityTaipei Dipartimento di Fisica e Astronomia dell’Univ.rsitàdi Padov. and INFN Sezione di Padov. PadovaItaly Univ.rsity of Roma Tre and INFN Sezione Roma Tre RomaItaly Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance Wuhan Univ.rsity WuhanChina INFN Milano Bicocca and Politecnico of Milano MilanoItaly National United Univ.rsity Miao-Li Dongguan Univ.rsity of Technology DongguanChina Tsinghua Univ.rsity BeijingChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Institute of Physics National Yang Ming Chiao Tung UniversityHsinchu North China Electric Power Univ.rsity BeijingChina Sun Yat-Sen Univ.rsity GuangzhouChina Beijing Institute of Spacecraft Env.ronment Engineering BeijingChina Univ.rsidade Estadual de Londrina LondrinaBrazil INFN Sez

The Jiangmen Underground Neutrino Observ.tory(JUNO)is a large liquid scintillator detector designed to explore many topics in fundamental *** this study,the potential of searching for proton decay in the p→νK^(+)mode with JUNO is *** kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for ***,the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed *** on these adv.ntages,the detection efficiency for the proton decay v.a p→νK^(+)is 36.9%±4.9%with a background lev.l of 0.2±0.05(syst)±0.2(stat)ev.nts after 10 years of data *** estimated sensitiv.ty based on 200 kton-years of exposure is 9.6×1033 years,which is competitiv. with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies.

关键词： proton decay grand unified theories JUNO liquid scintillator detector