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Shot-noise limited, supercontinuum-based optical coherence tomography

Light(Science & Applications) 2021年第7期10卷 1372-1384页

作者： Shreesha Rao D.S. mikkel Jensen Lars Grüner-nielsen Jesper Toft Olsen Peter Heiduschka Björn Kemper Jürgen Schnekenburger martin Glud mette mogensen niels møller israelsen Ole Bang DTU Fotonik Dept.of Photonics EngineeringTechnical University of DenmarkØrsteds Plads2800 Kongens LyngbyDenmark NKT Photonics A/S Blokken 843460 BirkerødDenmark Department of Ophthalmology University of Münster Medical CentreDomagkstr.15D-48149 MünsterGermany Biomedical Technology Center of the medical Faculty University of MünsterMendelstr.17D-48149 MünsterGermany Department of Dermatology Bisbebjerg HospitalUniversity of CopenhagenBispebjerg Bakke 232400 Copenhagen NVDenmark

We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography(SD-OCT)with an axial resolution of 5.9μm at a center wavelength of 1370 *** supercontinuumbased SD-OCT systems cannot be operated in the shot-noise limited detection regime because of severe pulse-topulse relative intensity noise of the supercontinuum *** overcome this disadvantage,we have developed a low-noise supercontinuum source based on an all-normal dispersion(ANDi)fiber,pumped by a femtosecond *** noise performance of our 90 mHz ANDi fiber-based supercontinuum source is compared to that of two commercial sources operating at 80 and 320 mHz repetition *** show that the low-noise of the ANDi fiber-based supercontinuum source improves the OCT images significantly in terms of both higher contrast,better sensitivity,and improved *** SD-OCT imaging of skin,retina,and multilayer stacks we conclude that supercontinuumbased SD-OCT can enter the domain of shot-noise limited detection.

关键词： fiber optical pumped

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Real-time high-resolution mid-infrared optical coherence tomography

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Light(Science & Applications) 2019年第1期8卷 1076-1088页

作者： niels m.israelsen Christian R.Petersen Ajanta Barh Deepak Jain mikkel Jensen Gunther Hannesschlager Peter Tidemand-Lichtenberg Christian Pedersen Adrian Podoleanu Ole Bang DTU Fotonik Technical University of Denmark2800 KgsLyngbyDenmark NORBLIS IVS Virumgade 35 DVirum 2830Denmark Research Center for Non-Destructive Testing(RECENDT) Altenberger Straße 694040 LinzAustria NLIR ApS Hirsemarken 1Farum 3520Denmark Applied Optics Group School of Physical SciencesUniversity of KentCanterbury CT27NHUK

The potential for improving the penetration depth of optical coherence tomography systems by using light sources with longer wavelengths has been known since the inception of the technique in the early ***,the development of mid-infrared optical coherence tomography has long been challenged by the maturity and fidelity of optical components in this spectral region,resulting in slow acquisition,low sensitivity,and poor axial *** this work,a mid-infrared spectral-domain optical coherence tomography system operating at a central wavelength of 4μm and an axial resolution of 8.6μm is *** system produces two-dimensional cross-sectional images in real time enabled by a high-brightness 0.9-to 4.7-μm mid-infrared supercontinuum source with a pulse repetition rate of 1 mHz for illumination and broadband upconversion of more than 1-μm bandwidth from 3.58–4.63μm to 820–865 nm,where a standard 800-nm spectrometer can be used for fast *** images produced by the mid-infrared system are compared with those delivered by a state-of-the-art ultra-high-resolution near-infrared optical coherence tomography system operating at 1.3μm,and the potential applications and samples suited for this technology are *** doing so,the first practical mid-infrared optical coherence tomography system is demonstrated,with immediate applications in real-time non-destructive testing for the inspection of defects and thickness measurements in samples that exhibit strong scattering at shorter wavelengths.

关键词： resolution repetition illumination

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