Shot-noise limited, supercontinuum-based optical coherence tomography
作者机构:DTU FotonikDept.of Photonics EngineeringTechnical University of DenmarkØrsteds Plads2800 Kongens LyngbyDenmark NKT Photonics A/SBlokken 843460 BirkerødDenmark Department of OphthalmologyUniversity of Münster Medical CentreDomagkstr.15D-48149 MünsterGermany Biomedical Technology Center of the Medical FacultyUniversity of MünsterMendelstr.17D-48149 MünsterGermany Department of DermatologyBisbebjerg HospitalUniversity of CopenhagenBispebjerg Bakke 232400 Copenhagen NVDenmark
出 版 物:《Light(Science & Applications)》 (光(科学与应用)(英文版))
年 卷 期:2021年第10卷第7期
页 面:1372-1384页
核心收录:
学科分类:0808[工学-电气工程] 070207[理学-光学] 0809[工学-电子科学与技术(可授工学、理学学位)] 07[理学] 08[工学] 0805[工学-材料科学与工程(可授工学、理学学位)] 0803[工学-光学工程] 0702[理学-物理学]
基 金:European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No.722380(the project SUPUVIR) Innovation Fund Denmark under the project J.No.4107-00011A(the project ShapeOCT) Det Frie Forskningsråd(DFF)under the project No.LOISE-4184-00532B(the project LOISE)
摘 要:We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography(SD-OCT)with an axial resolution of 5.9μm at a center wavelength of 1370 *** supercontinuumbased SD-OCT systems cannot be operated in the shot-noise limited detection regime because of severe pulse-topulse relative intensity noise of the supercontinuum *** overcome this disadvantage,we have developed a low-noise supercontinuum source based on an all-normal dispersion(ANDi)fiber,pumped by a femtosecond *** noise performance of our 90 MHz ANDi fiber-based supercontinuum source is compared to that of two commercial sources operating at 80 and 320 MHz repetition *** show that the low-noise of the ANDi fiber-based supercontinuum source improves the OCT images significantly in terms of both higher contrast,better sensitivity,and improved *** SD-OCT imaging of skin,retina,and multilayer stacks we conclude that supercontinuumbased SD-OCT can enter the domain of shot-noise limited detection.