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A Deformable Network with Attention Mechanism for Retinal Vessel Segmentation

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Journal of Beijing Institute of Technology 2024年第3期33卷 186-193页

作者： Xiaolong Zhu Wenjian Li weihang Zhang Dongwei Li Huiqi Li School of Information and Electronics Beijing Institute of TechnologyBeijing 100081China

The intensive application of deep learning in medical image processing has facilitated the advancement of automatic retinal vessel segmentation *** overcome the limitation that traditional U-shaped vessel segmentation networks fail to extract features in fundus image sufficiently,we propose a novel network(DSeU-net)based on deformable convolution and squeeze excitation residual *** deformable convolution is utilized to dynamically adjust the receptive field for the feature extraction of retinal *** the squeeze excitation residual module is used to scale the weights of the low-level features so that the network learns the complex relationships of the different feature layers *** validate the DSeU-net on three public retinal vessel segmentation datasets including DRIVE,CHASEDB1,and STARE,and the experimental results demonstrate the satisfactory segmentation performance of the network.

关键词： retinal vessel segmentation deformable convolution attention mechanism deep learning

A Modified CycleGAN for Multi-Organ Ultrasound Image Enhancement via Unpaired Pre-Training

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Journal of Beijing Institute of Technology 2024年第3期33卷 194-203页

作者： Haonan Han Bingyu Yang weihang Zhang Dongwei Li Huiqi Li School of Information and Electronics Beijing Institute of TechnologyBeijing 100081China School of Medical Technology Beijing Institute of TechnologyBeijing 100081China

Handheld ultrasound devices are known for their portability and affordability,making them widely utilized in underdeveloped areas and community healthcare for rapid diagnosis and early ***,the image quality of handheld ultrasound devices is not always satisfactory due to the limited equipment size,which hinders accurate diagnoses by *** the same time,paired ultrasound images are difficult to obtain from the clinic because imaging process is ***,we propose a modified cycle generative adversarial network(cycleGAN) for ultrasound image enhancement from multiple organs via unpaired *** introduce an ultrasound image pre-training method that does not require paired images,alleviating the requirement for large-scale paired *** also propose an enhanced block with different structures in the pre-training and fine-tuning phases,which can help achieve the goals of different training *** improve the robustness of the model,we add Gaussian noise to the training images as data *** approach is effective in obtaining the best quantitative evaluation results using a small number of parameters and less training costs to improve the quality of handheld ultrasound devices.

关键词： ultrasound image enhancement handheld devices unpaired images pre-train and finetune cycleGAN

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Genes & Diseases 2024年第1期11卷 358-366页

作者： Xinrui Dong Ye Li Xiaonan Sheng weihang Zhou Aijun Sun Huijuan Dai Department of Breast Surgery Renji HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai 200127China Department of Thyroid and Breast Oncological Surgery Xuzhou Medical College Affiliated Huaian HospitalHuai'anJiangsu 223001China

Ferroptosis is a novel form of regulated cell death characterized by iron-dependent excessive lipid *** core organelle involved in ferroptosis is ***-chondria undergoing ferroptosis are distinct from normal mitochondria in terms of morphology,biochemistry,gene expression,and energy *** increasing number of studies have shown that mitochondria and their associated metabolic pathways mediate ferroptosis in the development and progression of breast *** this review,we discuss the relevant research about ferroptosis in breast cancer and provide a comprehensive summary of mitochondrial regulation in ferroptosis from the perspective of lipid metabolism,oxidative phosphorylation,ion metabolism,glycometabolism,and nucleotide *** also summarize the appli-cation of mitochondrial metabolism-related pathways as ferroptosis treatment *** we provide new insights into the relationship between mitochondria,ferroptosis,and breast cancertreatment.

关键词： Breast cancer Cancer treatment Ferroptosis Lipid metabolism Mitochondria Oxidative phosphorylation

Simulation and evaluation study of atmospheric aerosol nonsphericity as a function of particle size

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Particuology 2024年第7期90卷 281-291页

作者： Qianjun Mao Xin nie School of Urban Construction Wuhan University of Science and TechnologyWuhan430065China College of New Energy and Materials Northeast Petroleum UniversityDaqing163318China

Aerosol nonsphericity causes great uncertainty in radiative forcing assessments and climate *** considerable studies have attempted to quantify this uncertainty,the relationship between aerosol nonsphericity and particle size is usually not considered,thus reducing the accuracy of the *** this study,a coupled inversion algorithm combining an improved stochastic particle swarm optimization algorithm and angular light scattering is used for the nonparametric estimation of aerosol nonsphericity variation with particle size,and the optimal sample selection method is employed to screen the *** on the verification of inversion accuracy,the variation of aerosol aspect ratio with particle size based on the ellipsoidal model in global regions has been obtained from Aerosol Robotic Network(AERONET)data,and the effect of nonsphericity on radiative forcing and dry deposition has been *** results show that the aspect ratio increases with particle size in all regions,with the maximum ranging from 1.4 to 1.8 in the desert,reflecting the differences in aerosol composition at different particle *** radiation calculations,considering aerosol nonsphericity makes the aerosol cooling effect weaker and surface radiative fluxes increase,but hardly changes the aerosol absorption,with maximum differences of 9.22%and 22.12%at the bottom and top of the atmosphere,***,the differences in radiative forcing between aspect ratios as a function of particle size and not varying with particle size are not significant,averaging less than 2%.Besides,the aspect ratio not varying with particle size underestimates the deposition velocity of small particles and overestimates that of large particles compared to that as a function of particle size,with maximum differences of 7%and 4%,respectively.

关键词： Aerosol nonsphericity Inversion Aspect ratio Radiative forcing Dry deposition velocity

Comprehensive insights:unraveling the mechanisms of gut commensals in glucose metabolism regulation

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Science China(Life Sciences) 2024年第2期67卷 414-417页

作者： Zhipeng Li Qixing nie Shao-Ping nie State Key Laboratory of Food Science and Resources China-Canada Joint Lab of Food Science and Technology(Nanchang)Key Laboratory of Bioactive Polysaccharides of Jiangxi ProvinceNanchang UniversityNanchang 330047China

The prevalence of type 2 diabetes(T2D)has escalated to a global epidemic,garnering widespread *** research utilizing germ-free(GF)mice,antibiotic treatments,and fecal microbiota transplantation approaches has established the critical role of gut microbiota in modulating glucose *** microbiota interacts with diets and the mucosal immune system,influencing intestinal permeability and the penetration of microbial products.

关键词： metabolism utilizing insight

Dielectric polymer grafted electrodes enhanced aqueous supercapacitors

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Nano Research 2024年第3期17卷 1525-1534页

作者： Shian Dong Kunming Shi Jie Chen Yingke Zhu Hongfei Li weihang Gao Zhenli Xu Qinglei Liu Xingyi Huang Shanghai Key Laboratory of Electrical Insulation and Thermal Aging Department of Polymer Science and EngineeringState Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong UniversityShanghai 200240China School of Mathematical Sciences Institute of Natural Sciences and MOE−LSCShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240China

Supercapacitors(SCs)have become increasingly important in electrical energy storage and delivery owing to their high power densities and long *** SCs are promising for large-scale engineering applications because of their low cost and ***,the low operating voltage and low energy density of aqueous SCs severely limit their practical *** this study,a nanoscale dielectric layer is grafted onto a graphene electrode to achieve both a high operating voltage and enhanced *** with an SC without dielectric grafting,a dielectric-enhanced SC(DESC)shows a higher capacitance by 2200%.The mechanism of the capacitance enhancement can be attributed to three factors:the dielectric polarization,the ions desolvation by the dielectric,and the enhanced quantum capacitance from charge transfer and ion adsorption in the polymer *** addition,a 2.5 V pouch DESC with a 1 M KCl electrolyte is confirmed to cycle up to 50,000 times with a capacitance retention of 87.5%.The DESC presents the optimal electrochemical properties after it is grafted with a 5 nm dielectric *** study provides new insights into the design of high-voltage and high-energy-density aqueous SCs.

关键词： supercapacitors dielectric polymer high voltage capacitance enhancement

Recent advances in small-scale hydrogel-based robots for adaptive biomedical applications

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Nano Research 2024年第2期17卷 649-662页

作者： Mingzhe nie Qilong Zhao Xuemin Du Institute of Biomedical&Health Engineering Shenzhen Institute of Advanced Technology(SIAT)Chinese Academy of Sciences(CAS)Shenzhen 518055China

Small-scale robots,ranging in size from micrometers to centimeters,have gained significant attention in the biomedical ***,conventional small-scale robots made of rigid materials encounter challenges in adapting themselves to the soft tissues and complicated environments of human *** to the rigid counterpart,small-scale hydrogel-based robots hold great promises due to their tissue-like low modulus,outstanding biocompatibility and accessible stimuli-responsive *** attributes offer small-scale hydrogel-based robots with multimodal locomotion and reinforced functions,further enhancing the adaptability in manipulation and tasks execution for various biomedical *** this review,we present recent advances in small-scale hydrogel-based *** first summarize the design principles of small-scale hydrogel-based robots including materials,fabrication techniques and manipulation strategies,then highlighting their upgraded functions and adaptive biomedical ***,we discuss existing challenges and future perspectives for small-scale hydrogel-based robots.

关键词： small-scale robot hydrogel locomotion multi-function adaptability

Collectively induced transparency and absorption in waveguide quantum electrodynamics with Bragg atom arrays

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Communications in Theoretical Physics 2024年第8期76卷 19-28页

作者： Haolei Cheng Wei nie Center for Joint Quantum Studies and Department of Physics School of ScienceTianjin UniversityTianjin 300350China Tianjin Key Laboratory of Low Dimensional Materials Physics and Preparing Technology Tianjin UniversityTianjin 300350China

Collective quantum states, such as subradiant and superradiant states, are useful for controlling optical responses in many-body quantum systems. In this work, we study novel collective quantum phenomena in waveguide-coupled Bragg atom arrays with inhomogeneous *** atoms without free-space dissipation, collectively induced transparency is produced by destructive quantum interference between subradiant and superradiant states. In a large Bragg atom array, multi-frequency photon transparency can be obtained by considering atoms with different frequencies. Interestingly, we find collectively induced absorption(CIA) by studying the influence of free-space dissipation on photon transport. Tunable atomic frequencies nontrivially modify decay rates of subradiant states. When the decay rate of a subradiant state equals to the free-space dissipation, photon absorption can reach a limit at a certain frequency. In other words, photon absorption is enhanced with low free-space dissipation, distinct from previous photon detection schemes. We also show multi-frequency CIA by properly adjusting atomic frequencies. Our work presents a way to manipulate collective quantum states and exotic optical properties in waveguide quantum electrodynamics(QED) systems.

关键词： waveguide quantum electrodynamics collective quantum states photon absorption Bragg atom array

Matched Volterra reduced-order model for an airfoil undergoing periodic translation

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Chinese Journal of Aeronautics 2024年第1期37卷 19-23页

作者： Lianrui nie Ziniu WU Department of Engineering Mechanics Tsinghua UniversityBeijing 100084China

This paper is devoted to application of the Reduced-Order Model(ROM)based on Volterra series to prediction of lift and drag forces due to airfoil periodic translation in transonic flow *** there is large amplitude oscillation of the relative Mach number,as appeared in helicopter rotor movement in forward flight,the conventional Volterra ROM is found to be *** cover such applications,a matched Volterra ROM,inspired from previous multistep nonlinear indicial response method based on Duhamel integration,is thus considered,in which the step motions are defined inside a number of equal intervals with both positive and negative step motions to match the airfoil forward and backward movement,and the kernel functions are constructed independently at each *** shows that,at least for the translation movement considered,this matched Volterra ROM greatly improves the accuracy of ***,the matched Volterra ROM,with the total number of step motions and thus the computational cost close to those of the conventional Volterra ROM method,has the additional advantage that the same set of kernels can match various translation motions with different starting conditions so the kernels can be predesigned without knowing the specific motion of airfoil.

关键词： Airfoil periodic translation Lift and drag Reduced-order model Transonic flow Unsteady flow