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Infectious Diseases of Poverty 2021年第2期10卷 78-78页

作者： Andrea J.Lund David HRehkopf Susanne HSokolow MMoustapha Sam nicolas Jouanard Anne-Marie Schacht Simon Senghor Assane Fall Gilles Riveau Giulio ADe Leo David lopez-Carr Emmett Interdisciplinary Program in Environment and Resources Stanford University473 Via Ortega Suite 226StanfordCAUSA 不详

Background:Water resources development promotes agricultural expansion and food *** are these benefits offset by increased infectious disease risk?Dam construction on the Senegal River in 1986 was followed by agricultural expansion and increased transmission of human *** the mechanisms linking these two processes at the individual and household levels remain *** investigated the association between household land use and schistosome infection in children.

关键词： Agriculture Exposure Livelihoods Planetary health Senegal Schistosomiasis Water contact

First report of L1014F kdr mutation in Culex quinquefasciatus in Mexico

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Insect Science 2016年第6期23卷 829-834页

作者： Gustavo Ponce Iram P. Sanchez Selene M. Garcia Jose M. Torrado Saul Lozano-Fuentes Beatriz lopez-Monroy Adriana E. Flores Facultad de Ciencias Biologicas Universidad Autonoma de Nuevo Leon A v. Universidad sin Cd. Universitaria San Nicolas de los GarzaN.L. 66455 Mexico Department of Microbiology Immunology and Pathology Colorado State University Fort Collins CO USA

The L1014F mutation in the voltage-sodium channel gene has been associated with resistance to DDT and pyrethroids in various arthropod species including mosquitoes. We determined the frequency of the L1014F kdr mutation in 16 field populations of Culex quinquefasciatus from Northeastern Mexico collected between 2008 and 2013. The L1014F was present in all populations analyzed with the lowest frequency （3.33%） corresponding to the population from Monclova collected in 2012, and the highest frequency （63.63%） from the Monterrey population collected in 2012. The presence of a kdr mutation in populations of Cx. quinquefasciatus from northeastern Mexico provides evidence ofpyrethroid resistance. This requires a special attention, considering that pyrethroid-based insecticides are commonly used in vector-control campaigns, especially against Aedes aegypti （L.）.

关键词： Culex quinquefasciatus insecticide resistance kdr L 1014F mutation

Novel Kdr mutations (K964R and A943V) in pyrethroid-resistant populations of Triatoma mazzottii and Triatoma longipennisUoro Mexico and detoxifying enzymes

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Insect Science 2019年第5期26卷 809-820页

作者： Jesus Davila-Barboza O.Karina Villanueva-Segura Beatriz lopez-Monroy Gustavo Ponce-Garcia Cristina Bobadilla-Utrera Mayela Montes-Rincon Zinnia J.Molina-Garza Juan I.Arredondo-Jimenez Iram P.Rodriguez-Sanchez Pablo C.Manrique-Saide Adriana E.Flores Universidad Autonoma de Nuevo Leon (UANL) Facultad de Ciencias BiologicasSan Nicolas de los GarzaNLMexico Laboratorio Estatal de Salud Publica de los Servicios de Salud de Veracruz VeracruzMexico Campus de Ciencias Biologicas y Agropecuarias Unidad Colaborativa para Bioensayos EntomologicosUniversidad Autonoma de YucatanMeridaYucatanMexico

Although having five different ways of transmission the vector-borne is the principal way of transmission of Chagas disease, which involves insects of the subfamily Triatominae (Hemiptera: Reduviidae). Nineteen of the 31 species that occur in Mexico are associated with humans, and all are capable of transmitting the disease. Pyrethroids are the insecticides recommended for the control of these vectors in Mexico. We determined the susceptibility to the pyrethroids dcltamethrin and permethrin of peridomestic populations of Triatoma mazzottii Usinger and two populations of Triatoma longipetmis Usinger in comparison with a reference strain for each species. Bioassays were performed for the determination of the LD50 for both field populations and reference strains. A maximum of 27 fold resistance to deltamethrin was observed in T. mazzottii, meanwhile, for permethrin, T. longipennis from Jalisco show the highest value of 3.19 fold. There was significantly increased activity of esterases in field populations in comparison with their corresponding reference strain. The results of the search of kdr mutations related to the resistance to deltamethrin and permethrin in the evaluated species show the presence of mutations in the field populations, as is the case with individuals of T. mazzottii, for which the mutation was found A943V, and for the two populations of T. longipennis included in this study, we report the presence of the kdr mutation K964R. Evaluation of the various mechanisms involved in resistance to pyrethroids in triatomines from Mexico could guide us to the real justification for insecticide resistance monitoring.

关键词： detoxifying enzymes kdr pyrethroids Triatoma longipennis Triatoma mazzottii

Cortical columns(barrels)display normal size in the brain’s primary somatosensory cortex of mice carrying null mutations of the insulin receptor substrate 1 gene:A preliminary report

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Advances in Bioscience and Biotechnology 2013年第10期4卷 945-948页

作者： Marta lopez-Santibanez Guevara Eileen Uribe-Querol Alma Lilia Fuentes Farias Esperanza Melendez-Herrera Agustine Joseph D’Ercole Gabriel Gutierrez-Ospina Departamento de Biologia Celular y Fisiologia Instituto de Investigaciones BiomedicasUniversidad Nacional Autonoma de MexicoMexico D.F.Mexico Division de Estudios de Posgrado e Investigacion Facultad de OdontologiaUniversidad Nacional Autonoma de MexicoMexico D.F.Mexico Departamento de Zoologia Instituto de Investigaciones sobre los Recursos NaturalesUniversidad Michoacana de San Nicolas de HidalgoMoreliaMexico Department of Pediatrics The University of North Carolina at Chapel HillChapel HillUSA Coordinacion de Psicofisiologia Facultad de PsicologiaUniversidad Nacional Autonoma de MexicoMexico D.F.Mexico

Circuits in barrels of the rodent brain’s primary somatosensory (S1) cortex build up following constructivist rules. Previous evidence in mice supports that the precise addition of barrel neuropil is promoted by insulin-like growth factor-1 (IGF-1). The signaling cascades mediating this response remain undetermined. To address whether the effects of IGF-1 upon the growth of S1 circuits are mediated by insulin receptor substrate-1 (IRS-1), we studied barrel size in adult mice having the IRS-1 gene knocked out (IRS-1 ko). Our results reveal that barrel size is similar between wild type and IRS-1 ko mice suggesting that IRS-1 is not essential for barrel circuitry growth. Hence, investigations aimed at exploring other substrates activated by IGF-1, namely IRS-2 and IRS-4, are needed to reveal signaling pathways that mediate the precise addition of S1 neuronal circuitry.

关键词： Barrel Cortex Neuronal Circuit Assemblage Trophic Interactions Constructivism

Water Quality Assessment of a Tropical Mexican Lake Using Multivariate Statistical Techniques

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Journal of Environmental Protection 2015年第3期6卷 215-224页

作者： Jessica Badillo-Camacho Eire Reynaga-Delgado Isela Barcelo-Quintal Pedro F.Zarate del Valle Ulrico J.lopez-Chuken Eulogio Orozco-Guareno Jorge Israel AlvarezBobadilla Sergio Gomez-Salazar Departamento de Quimica Universidad de Guadalajara-Centro Universitario de Ciencias Exactas e IngenieriasGuadalajaraMexico Departamento de Farmacobiologia Universidad de Guadalajara-Centro Universitario de Ciencias Exactas e IngenieriasGuadalajaraMexico Departamento de Ciencias Basicas Universidad Autonoma MetropolitanaUnidad AzcapotzalcoMexico D.F.Mexico Facultad de Ciencias Quimicas Universidad Autonoma de Nuevo LeonSan Nicolas de los GarzaMexico Departamento de Ingenieria Quimica Universidad de Guadalajara-Centro Universitario de Ciencias Exactas e IngenieriasGuadalajaraMexico

Water quality of Mexican tropical lake Chapala was assessed through multivariate statistical techniques, cluster analysis (CA) and principal component analysis (PCA) at ten different monitoring sites for ten physicochemical variables and six metals. This study evaluated and interpreted complex water quality data sets and apportioned of pollution sources to get better information about water quality. From descriptive statistics results, the highest concentrations of metals occurred during the dry season, and this trend was explained by the fact that an unusual rainy event occurred during the month of February 2009 and brought metals into the lake by runoffs from nearby mountains. According to international criteria for water consumption by aquatic organisms [USEPA], only Zn concentration values were below these criteria whereas the values of Ni, Pb, Cd and Fe were above the corresponding values set in these criteria (Ni: 52 μg·L-1, Pb: 2.5 μg·L-1, Cd: 0.25 μg·L-1, and Fe: 1000 μg·L-1). The correlations were observed by PCA, which were used to classify the samples by CA, based on the PCA scores. Seven significant cluster groups of sampling locations—(sites 4 and 5), (sites 3 and 9), (site 7), (site 10), (sites 2 and 6), (site 8) and (site 1)— were detected on the basis of similarity of their water quality. The results revealed that the stress exerted on the lake caused by waste sources follows the order: domestic > agricultural > industrial.

关键词： Multivariate Statistical Analysis toxic Metals Water Quality Lake Pollution

Increased serotonin concentration and tryptophan hydroxylase activity in reproductive organs of copulator males:a case of adaptive plasticity

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Advances in Bioscience and Biotechnology 2011年第2期2卷 75-84页

作者： Ana Ingrid Pichardo Jose L.Tlachi-lopez Francisco Jimenez-Trejo Alma L.Fuentes-Farias Armida Baez-Saldana Maria L.Molina-Ceron Gabriel Manjarrez-Gutierrez Gabriel Gutierrez-Ospina Rosa Angelica Lucio Departamento de Biologia Celular y Fisiologia Instituto de Investigaciones BiomedicasUniversidad Nacional Autonoma de MexicoCiudad Universitaria 04510MexicoD.F.Mexico Centro Tlaxcala de Biologia de la Conducta Universidad Autonoma de TlaxcalaCarretera Tlaxcala-Puebla km 1.5 s/nLoma Xicotencatl90062TlaxcalaMexico Departamento de Farmacologia Facultad de MedicinaUniversidad Nacional Autonoma de MexicoCiudad Universitaria 04510MexicoD.F.Mexico Laboratorio de Invertebrados y Ecofisiologia Facultad de BiologiaUniversidad Michoacana de San Nicolas de HidalgoCiudad Universitaria 58030MichoacanMexico Unidad de Investigacion Biomolecular Hospital de CardiologiaCentro Medico Nacional Siglo XXIInstituto Mexicano del Seguro Social 06720MexicoD.F.Mexico

Individual male rats may systematically display or not copulatory behavior when paired with receptive females. Although these phenotypes are associated with differences in brain organization and function, they might also do so at the level of the reproductive organs. We then used high performance liquid chromatography to quantify serotonin concentration and the activity of tryptophan hydroxylase in the reproductive organs of copulator and non-copulator males. Sexual behavior display was compared between groups and parameters of fertility and reproductive fitness were determined for copulator males. Copulator males had higher concentrations of serotonin in the epididymis, testicle and ventral prostate than their non-copulator counterparts, as it was found for epididymal and testicular tryptophan hydroxylase activity. However, preliminary data shows that serotonin elevation occurs in copulator males only until they have accumulated several sexual encounters, so it might be a response to genital gratification or sexual rewarding. Interestingly, only epididymal serotonin concentration correlated with reproductive fitness, offspring number, mating success and seminal plug volume in copulator males. Our results support that copulator and non-copulator male rats feature a phenotype-specific serotoninergic tone in the epididymis, testicle and ventral prostate gland. The observation documenting that epididymal serotonin concentration correlated with parameters that monitor male fertility and reproductive fitness in copulator males predicts that epididymal factors increase their chances of parenting offspring.

关键词： Sexual Accessory Glands Copulation Indolamines Seminal Fluid Seminal Plug Successful Mating Reproductive Fitness

Biological and Chemical Control in Rot Root in Avocado by Phytophthora cinnamomi Rands

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Journal of Agricultural Science and Technology(A) 2012年第7期2卷 882-887页

作者： Ma. Blanca Nieves Lara-Chavez Teresita del Carmen Avila-Val Jestus Alejandro Guerrero-Tejeda Francisco Said Barriga-Gonzalez Eulalio Venegas-Gonzalez Salvador Aguirre-Paleo Margarita Vargas-Sandoval Hector Guillen Andrade Satul Rodriguez-lopez Universidad Michoacana de San nicolas de Hidalgo Facultad de Agrobiologla "Presidente Juarez" Uruapan Michoacan C.P.60190 Mexico

＂Avocado sadness＂ caused by the Oomycete Phytophthora cinnamomi Rands, is one of the main diseases affecting this fruit crop in Michoacan, M6xico, without having an efficient control strategy for that. In this research three Trichoderma isolates and Ridomil Gold 4E fungicide were tested in avocado trees infected with this pathogen using the growing and coloring vegetative flow growing. Results were analyzed with an experimental design completely random with four treatments and repetitions. Different responses were presented form avocado trees to each treatment. Trichoderma erinaceum Bissett, Kubicek ＆ Szackacs treatment was the best controlling disease in trees with grade II and III damage. Trichoderma aggressivum Samuels ＆ W. Gams controlled better in trees with grade III damage. At last, Trichoderma arundinaceum Zafari, Graef. and Samuels were the best controlling trees with the highest grade damage. Fungicide Ridomil Gold 4E controlled the disease in trees with the lowest grade damage （I and II）, their medias were similar to witness.

关键词： Biological and chemical control Trichoderma aggressivum T. erinaceum T. arundinaceum Ridomil Gold 4E.