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Surgical apgar score predicts early complication in transfemoral amputees:Retrospective study of 170 major amputations

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World Journal of Orthopedics 2016年第12期7卷 832-838页

作者： Christian Wied nicolai b foss Morten T Kristensen Gitte Holm Thomas Kallemose Anders Troelsen Department of Orthopedic Surgery Copenhagen University Hospital Hvidovre Department of Anesthesiology and Intensive Care Copenhagen University Hospital Hvidovre Physical Medicine and Rehabilitation Research-Copenhagen Department of Physical TherapyCopenhagen University Hospital Hvidovre Clinical Research Centre Copenhagen University Hospital Hvidovre

AIM To assess whether the surgical apgar score(SAS) is a prognostic tool capable of identifying patients at risk of major complications following lower extremity amputations *** This was a single-center,retrospective observational cohort study conducted between January 2013 and April 2015. All patients who had either a primary transtibial amputation(TTA) or transfemoral amputation(TFA) conducted at our institution during the study period were assessed for inclusion. All TTA patients underwent a standardized one-stage operative procedure(ad modum Persson amputation) performed approximately 10 cm below the knee joint. All TTA procedures were performedwith sagittal flaps. TFA procedures were performed in one stage with amputation approximately 10 cm above the knee joint,performed with anterior/posterior flaps. Trained residents or senior consultants performed the surgical procedures. The SAS is based on intraoperative heart rate,blood pressure and blood loss. Intraoperative parameters of interest were collected by revising electronic health records. The first author of this study calculated the SAS. Data regarding major complications were not revealed to the author until after the calculation of SAS. The SAS results were arranged into four groups(SAS 0-4,SAS 5-6,SAS 7-8 and SAS 9-10). The cohort was then divided into two groups representing low-risk(SAS ≥ 7) and highrisk patients(SAS blished threshold. The outcome of interest was the occurrence of major complications and death within 30-d of *** A logistic regression model with SAS 9-10 as a reference showed a significant linear association between lower SAS and more postoperative complications [all patients: OR = 2.00(1.33-3.03),P = 0.001]. This effect was pronounced for TFA [OR = 2.61(1.52-4.47),P bserved for the high-risk group compared to the low-risk group for all patients [OR = 2.80(1.40-5.61),P = 0.004] and for the TFA sub-

关键词： Surgical apgar score Mortality Transfemoral amputation Post-operative complication Lower extremity amputation

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Tourniquets do not increase the total blood loss or reamputation risk in transtibial amputations

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World Journal of Orthopedics 2017年第1期8卷 62-67页

作者： Christian Wied Peter T Tengberg Gitte Holm Thomas Kallemose nicolai b foss Anders Troelsen Morten T Kristensen Depart-ment of Orthopedic Surgery Copenhagen University Hospital Hvidovre Clinical Research Centre Copenhagen University Hospital Hvidovre Department of Anesthesiology and Intensive Care Copenhagen University Hospital Hvidovre Physical Medicine and Rehabilita-tion Research--Copenhagen Department of Physical TherapyCopenhagen University Hospital Hvidovre

AIM To investigate the total blood loss(TbL) and the safety with respect to the re-amputation rate after transtibial amputation(TTA) conducted with and without a tourniquet. METHODS The study was a single-centre retrospective cohort study of patients with a primary TTA admitted between January 2013 and April 2015. All patients with a primary TTA were assessed for inclusion if the amputation was performed because of arteriosclerosis or diabetic complications. All patients underwent a standardized TTA procedure that was performed approximately 10 cm below the knee joint and performed with sagittalflaps. The pneumatic tourniquet, when used, was inflated around the femur to a pressure of 100 mmH g above the systolic blood pressure. The number of blood transfusions within the first four postoperative days was recorded. The intraoperative blood loss(ObL), which is defined as the volume of blood lost during surgery, was determined from the suction volume and by the weight difference of the surgical dressings. The trigger for a blood transfusion was set at a decrease in the Hgb level blood cells containing 245 m L per portion, which equals 55 g/L of haemoglobin. The TbL during the first four postoperative days was calculated based on the haemoglobin level and the estimated blood volume. The re-amputation rate was evaluated within 30 d. RESULTS Seventy-four out of 86 consecutive patients who underwent TTA within the two-year study period were included in the analysis. Of these, 38 were operated on using a tourniquet and 36 were operated on without using a tourniquet. There were no significant preoperative differences between the groups. The patients in both groups had a postoperative decrease in their Hgb level compared with preoperative baseline values. The patients operated on using a tourniquet received approximately three millilitres less blood transfusion per kilogram body weight compared with patients o

关键词： Total blood loss Intraoperative blood loss Transtibial amputation Lower extremity amputation Pneumatic tourniquet Re-amputation

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Collisionless shock acceleration of protons in a plasma slab produced in a gas jet by the collision of two laser-driven hydrodynamic shockwaves

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Matter and Radiation at Extremes 2024年第2期9卷 12-25页

作者： J.-R.Marquès L.Lancia P.Loiseau P.Forestier-Colleoni M.Tarisien E.Atukpor V.bagnoud C.brabetz F.Consoli J.Domange F.Hannachi P.Nicolaï M.Salvadori b.Zielbauer LULI CNRSÉcole PolytechniqueCEASorbonne UniversitéInstitut Polytechnique de Paris91128 Palaiseau CedexFrance CEA DAMDIF91297 Arpajon CedexFrance UniversitéParis-Saclay CEALMCE91680 Bruyères-le-ChatelFrance CENbG CNRS-IN2P3Universitéde Bordeaux33175 Gradignan CedexFrance GSI Helmholtzzentrum für Schwerionenforschung GmbH Planckstraße 164291 DarmstadtGermany University of Darmstadt Schloßgartenstr.764289 DarmstadtGermany ENEA Fusion and Technologies for Nuclear Safety Department C.R.FrascatiVia Enrico Fermi 45FrascatiRomeItaly CELIA Universitéde Bordeaux–CNRS–CEA33405 TalenceFrance UniversitéParis-Saclay CEALIDYL91191 Gif-sur-YvetteFrance

We have recently proposed a new technique of plasma tailoring by laser-driven hydrodynamic shockwaves generated on both sides of a gas jet[Marquès et al.,*** 28,023103(2021)].In a continuation of this numerical work,we study experimentally the influence of the tailoring on proton acceleration driven by a high-intensity picosecond laser in three cases:without tailoring,by tailoring only the entrance side of the picosecond laser,and by tailoring both sides of the gas *** tailoring,the acceleration is transverse to the laser axis,with a low-energy exponential spectrum,produced by Coulomb *** the front side of the gas jet is tailored,a forward acceleration appears,which is significantly enhanced when both the front and back sides of the plasma are *** forward acceleration produces higher-energy protons,with a peaked spectrum,and is in good agreement with the mechanism of collisionless shock acceleration(CSA).The spatiotemporal evolution of the plasma profile is characterized by optical shadowgraphy of a probe *** refraction and absorption of this beam are simulated by post-processing 3D hydrodynamic simulations of the plasma *** with the experimental results allows estimation of the thickness and near-critical density of the plasma slab produced by tailoring both sides of the gas *** parameters are in good agreement with those required for CSA.

关键词： acceleration hydrodynamic collision

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Radioisotope production using lasers:From basic science to applications

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Matter and Radiation at Extremes 2024年第3期9卷 31-44页

作者： M.R.D.Rodrigues A.bonasera M.Scisciò J.A.Pérez-Hernández M.Ehret F.Filippi P.L.Andreoli M.Huault H.Larreur D.Singappuli D.Molloy D.Raffestin M.Alonzo G.G.Rapisarda D.Lattuada G.L.Guardo C.Verona Fe.Consoli G.Petringa A.McNamee M.La Cognata S.Palmerini T.Carriere M.Cipriani G.Di Giorgio G.Cristofari R.De Angelis G.A.P.Cirrone D.Margarone L.Giuffrida D.batani P.nicolai K.batani R.Lera L.Volpe D.Giulietti S.Agarwal M.Krupka S.Singh Fa.Consoli Cyclotron Institute Texas A&M UniversityCollege StationTexas 77840USA Laboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare(LNS-INFN)CataniaItaly ENEA Fusion and Technologies for Nuclear Safety and Security Department-CFrascatiItaly Centro de Láseres Pulsados(clpu) VillamayorSpain Universidad de Salamanca SalamancaSpain Centre Lasers Intenses et Applications(CELIA) Universitéde BordeauxCNRSCEATalenceFrance Hb11 Energy Holdings Pty FreshwaterNew South WalesAustralia School of Mathematics and Physics Queen’s University BelfastBelfastUnited Kingdom Dipartimento di Fisica e Astronomia“E.Majorana ”Università di CataniaCataniaItaly Facoltàdi Ingegneria e Architettura Universitàdegli Studi di Enna“Kore”EnnaItaly Dipartimento di Ingegneria Industriale Universitàdi Roma“Tor Vergata”RomaItaly Dipartimento di Fisica e Geologia Universitàdegli Studi di PerugiaPerugiaItaly Istituto Nazionale di Fisica Nucleare Sezione di PerugiaPerugiaItaly ELI beamlines Facility the Extreme Light Infrastructure ERICDolni BrezanyCzech Republic ETSIA Universidad Politécnica de MadridMadridSpain Dipartimento Fisica “E.Fermi”Universitàdi Pisa and INFNPisaItaly FZU–Institute of Physics of Czech Academy of Sciences PragueCzech Republic Institute of Plasma Physics of Czech Academy of Sciences PragueCzech Republic

The discovery of chirped pulse amplification has led to great improvements in laser technology,enabling energetic laser beams to be compressed to pulse durations of tens of femtoseconds and focused to a few *** with energies of tens of MeV can be accelerated using,for instance,target normal sheath acceleration and focused on secondary *** such conditions,nuclear reactions can occur,with the production of radioisotopes suitable for medical *** use of high-repetition lasers to produce such isotopes is competitive with conventional methods mostly based on *** this paper,we study the production of^(67)Cu,^(63)Zn,^(18)F,and^(11)C,which are currently used in positron emission tomography and other *** the same time,we study the reactions^(10)b(p,α)^(7)be and^(70)Zn(p,4n)^(67)Ga to put further constraints on the proton distributions at different angles,as well as the reaction^(11)b(p,α)^(8)be relevant for energy *** experiment was performed at the 1 PW laser facility at VegaⅢin Salamanca,*** distributions of radioisotopes in the forward(with respect to the laser direction)and backward directions were measured using a high purity germanium *** results are in reasonable agreement with numerical estimates obtained following the approach of Kimura and bonasera[*** ***.,Sect.A 637,164–170(2011)].

关键词： purity estimates backward

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Soil application of beauveria bassiana GHA against apple sawfly, Hoplocampa testudinea （Hymenoptera： Tenthredinidae）： Field mortality and fungal persistence

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Insect Science 2016年第6期23卷 854-868页

作者： Weronika Swiergiel nicolai V. Meyling Mario Porcel birgitta Ramert Department of Plant Protection biology Unit of Integrated Plant Protection Swedish University of Agricultural Sciences (SLU) AlnarpSweden Department of Plant and Environmental Sciences University of Copenhagen Copenhagen Denmark

Low impact alternatives to synthetic insecticides for the control of apple sawfly （Hoplocampa testudinea Klug） are scarce encumbering pest management in organic apple orchards. We investigated the soil persistence and field efficacy of the entomopathogenic fungus beauveria bassiana （balsamo） Vuillemin （botaniGard） against apple sawfly under common organic orchard practices. We also assessed the efficacy of b. bassiana GHA and Metarhiziurn brunneum Petch （indigenous strain） against sawfly in the laboratory. Larvae treated with either fungus in the laboratory died faster than control larvae and displayed 49.4%-68.4% mycosis. In the field, b. bassiana density remained high in the week after application, during larval descent to the soil. Fungal density decreased to 25% at 49 d after application and to 0.4% after 55 weeks. Molecular markers revealed that the majority of fungal isolates recovered comprised the applied b. bassiana strain GHA. Larvae pupating in soil cages in the orchard for 49 d displayed 17% mycosis. The high efficacy under laboratory conditions was not seen in the field. b. bassiana application resulted in densities above the upper natural background level during the growing season, but reversion to background levels occurred within a year. It remains to be investigated whether this has a detrimental effect on nontarget organisms. Additional work is needed to bridge the knowledge gap between laboratory and field efficacy in orchards.

关键词： biological control crop protection entomopathogenic fungi integrated pest management Metarhizium organic orchard

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经验、惯例与组织能力的内在起源：刺激贫乏①

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理论经济学 2012年第4期 1-22页

作者： Teppo Felin nicolai J.foss

本文中，我们将讨论组织惯例和组织能力的起源与涌现问题。首先，我们认为由现有惯例与能力文献所详细阐明的关键前因与机制问题具有理论与内生性相关的一致性。具体来讲，我们解释了组织惯例和组织能力文献的经验主义和行为主义基础，... 详细信息

本文中，我们将讨论组织惯例和组织能力的起源与涌现问题。首先，我们认为由现有惯例与能力文献所详细阐明的关键前因与机制问题具有理论与内生性相关的一致性。具体来讲，我们解释了组织惯例和组织能力文献的经验主义和行为主义基础，以及现有文献对作为惯例与能力的关键前因与机制的经验、重复与观察的强调。在此讨论的基础上，我们强调了几个内生性相关的问题，即：①起源和因果关系的问题；②极端问题；③意向性问题；④新知识的问题；⑤环境问题。我们引入了“刺激贫乏”论(poverty of stimulus)，并讨论一个内在主义者或理性主义者基于选择的分析方法如何能够提供一个更富有成效的(虽然是初步的)理解组织行为和组织能力的基础。

关键词：惯例起源内在主义

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Year-round cooling and thermal stabilization of water-saturated soils under engineering structures

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Research in Cold and Arid Regions 2017年第3期9卷 258-260页

作者： Vladimir Moiseev nicolai Vasiliev Tatyana Komarova Olga Komarova Department of Mathematics Emperor Alexander I St.Petersburg State Transport University Static Research of Soils Laboratory B.E.Vedeneev VNIIG JSC DISIST Scientific Center

We consider the problem of year-round cooling of water-saturated soil to freezing temperatures in order to convert it into a state of permafrost.A new soil-cooling apparatus is *** apparatus is to be made in modular form and connected to passive-active thermal piles(thermosyphons).The estimated capacity of one apparatus allows simultaneous use of up to 1,000 thermal piles for ground *** apparatus is based on natural sources of energy:solar radiation and wind;and it can be used for soil *** approach can prevent thawing of soft soils under railways and roads,as well as under buildings or structures,in an area of more than tens of *** apparatus has no mechanical moving parts and can operate for a long time in stand-alone mode without staff involvement.

关键词： thermopiles frozen soil preventing of thawing the apparatus for cooling

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经验、惯例与组织能力的内在起源:刺激贫乏

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演化与创新经济学评论 2011年第2期 1-22页

作者： Teppo Felin nicolai J.foss 王焕祥(译) 陈劲(校) 美国杨百翰(brigham Young)大学马里奥特(Marriott)管理学院丹麦哥本哈根商学院挪威经济工商管理商学院战略与管理系浙江大学科教发展战略研究中心嘉兴学院演化与创新经济学研究中心浙江大学公共管理学院

本文中,我们将讨论组织惯例和组织能力的起源与涌现问题。首先,我们认为由现有惯例与能力文献所详细阐明的关键前因与机制问题具有理论与内生性相关的一致性。具体来讲,我们解释了组织惯例和组织能力文献的经验主义和行为主义基础,以及... 详细信息

本文中,我们将讨论组织惯例和组织能力的起源与涌现问题。首先,我们认为由现有惯例与能力文献所详细阐明的关键前因与机制问题具有理论与内生性相关的一致性。具体来讲,我们解释了组织惯例和组织能力文献的经验主义和行为主义基础,以及现有文献对作为惯例与能力的关键前因与机制的经验、重复与观察的强调。在此讨论的基础上,我们强调了几个内生性相关的问题,即:①起源和因果关系的问题;②极端问题;③意向性问题;④新知识的问题;⑤环境问题。我们引入了'刺激贫乏'论(poverty of stimulus),并讨论一个内在主义者或理性主义者基于选择的分析方法如何能够提供一个更富有成效的(虽然是初步的)理解组织行为和组织能力的基础。

关键词：惯例起源内在主义

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How should liver hypertrophy be stimulated?A comparison of upfront associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)and portal vein embolization(PVE)with rescue possibility

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Hepatobiliary Surgery and Nutrition 2021年第1期10卷 1-8页

作者： Ernesto Sparrelid Kristina Hasselgren bård Ingvald Røsok Peter Nørgaard Larsen nicolai Aagaard Schultz Ulrik Carling Eva Fallentin Stefan Gilg Per Sandström Gert Lindell bergthor björnsson Department of Clinical Science Intervention and TechnologyDivision of SurgeryKarolinska InstituteKarolinska University HospitalStockholmSweden Department of Surgery and Clinical and Experimental Medicine Linköping UniversityLinköpingSweden Department of Hepato-Pancreato-biliary Surgery Oslo University HospitalOsloNorway Department of Surgical Gastroenterology and Transplantation RigshospitaletUniversity of CopenhagenDenmark Department of Radiology and Nuclear Medicin RikshospitaletOslo University HospitalOsloNorway Department of Radiology RigshospitaletUniversity of CopenhagenCopenhagenDenmark Department of Surgery Skane University HospitalLundSweden

background:The role of associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)in comparison to portal vein embolization(PVE)is *** aim of this study was to compare successful resection rates(RR)with upfront ALPPS *** with rescue ALPPS on demand and to compare the hypertrophy of the liver between ALPPS and PVE plus subsequent rescue ***:A retrospective analysis of all patients treated with PVE for colorectal liver metastasis(CRLM)or ALPPS(any diagnosis,rescue ALPPS included)at five Scandinavian university hospitals during the years 2013-2016 was conducted.A Chi-square test and a Mann-Whitney U test were used to assess the difference between the groups.A successful RR was defined as liver resection without a 90-day ***:A total of 189 patients were *** RR was in 84.5%of the patients with ALPPS upfront and in 73.3%of the patients with PVE and rescue ALPPS on demand(P=0.080).The hypertrophy of the future liver remnants(FLRs)with ALPPS upfront was 71%(48-97%)compared to 96%(82-113%)after PVE and rescue ALPPS(P=0.010).Conclusions:Upfront ALPPS offers a somewhat higher successful RR than PVE with rescue ALPPS on *** sequential combination of PVE and ALPPS leads to a higher overall degree of hypertrophy than upfront ALPPS.

关键词： Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS) liver surgery colorectal liver metastases(CRLM) portal vein embolization(PVE)

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In memorial——Anton Antonov(1977-2012)

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Chinese birds 2012年第4期3卷 339-340页

作者： Eivin RSKAFT brd G.STOKKE Frode fossY Arne MOKSNES Department of biology Norwegian University of Science and Technology(NTNU)

正About eight years ago we received an email from *** is not uncommon to receive such emails from former Eastern bloc or other countries,particularly from the third ***,this was a special *** the English was rather na... 详细信息

关键词： bG Anton Antonov

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