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药物治疗错误:患者的角色

中国药物警戒 2011年第3期8卷 190-192页

作者：梁海涛（译）付文焕王大猷（校）复旦大学附属华山医院上海200040

药物治疗错误与药物不良反应不同，尽管两者可能有着重叠之处。Ferner和Aronson将药物治疗错误定义为“治疗过程中导致或者有可能导致患者受到伤害的失败”。

关键词：药物治疗错误患者药物不良反应

SHANGHAI SHADOWS Photographer nicky Almasy captures a negative of Shanghai's vibrant evolution.

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城市漫步（上海版、英文） 2016年第3期 12-16页

作者： MARIANNA CERINI nicky ALMASY(图) 不详

Shanghai is not a subdued city It is loud,teeming with myriad facets,a constant whirlwind of shifts and *** around,and yoifll see that in the metropolis'mad plethora of colors,architecture and *** corner has a story to tell,from the quaint tree-lined streets of the former French Concession to the few crumbling shikumens still standing and the glass and steel structures of more recent years.

关键词： evolution. colors street

CA19-9 antigen levels can distinguish between benign and malignant pancreaticobiliary disease

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Hepatobiliary & Pancreatic Diseases International 2009年第6期8卷 620-626页

作者： Gareth Morris-Stiff Mary Teli nicky Jardine Malcolm CA Puntis Department of Surgery University Hospital of Wales

BACKGROUND:CA19-9 is a carbohydrate tumor-associated antigen which is frequently upregulated in pancreatobiliary ***,it may also be elevated in patients with jaundice in the absence of a tumor due to biliary obstruction,and in other non-hepato-pancreatico-biliary *** study aimed to evaluate whether CA19-9 levels could accurately differentiate between benign and malignant pancreatobiliary ***:All patients referred to a single surgeon for investigation of pancreaticobiliary disease in 2003 in whom a firm diagnosis had been established were *** malignant disease,a histological diagnosis was required but for benign disease a firm radiological diagnosis was deemed *** patients were divided into 4 categories:pancreatic adenocarcinoma(PCa);cholangiocarcinoma(CCa);chronic pancreatitis(CP)and biliary calculous disease(Calc).Bilirubin and alkaline phosphatase levels corresponding to the point of assessment of CA19-9 were also ***:Final diagnoses were made of pancreatic adenocarcinoma(PCa,n=73),cholangiocarcinoma(CCa,n=19),ampullary carcinoma(Amp,n=7),neuroendocrine carcinoma(Neu,n=4),duodenal carcinoma(Duo,n=3),chronic pancreatitis(CP,n=115),and biliary calculous disease(Calc,n=27).Median CA19-9 levels(U/ml)were:PCa,653;CCa,408;Duo,403;Calc,27;CP,19;Neu,10.5;Amp,8(reference range:0-37).The CA19-9 levels were significantly greater for malignant than for benign disease,could differentiate PCa from CCa/Duo,and were significantly higher in unresectable than in resectable *** sensitivity,specificity,positive predictive value(PPV)and negative predictive value(NPV)for CA19-9 were 84.9%,69.7%,67.7%and 86.1%,respectively.A ROC analysis provided an area under the curve for CA19-9 of 0.871(0.820-0.922),giving an optimal CA19-9 of 70.5 U/ml for differentiating benign from malignant *** this cut-off,the sensitivity was 82.1%,while specificity,PPV and NPV improved to 85.9%,81.3%and 86.5%,*** sta

关键词： CA19-9 antigen pancreatic disease biliary tract disease malignant benign

Experimental Investigation of Thermal Performance of Novel Finned Radiators for Automotive Cooling System

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Journal of Thermal Science 2024年第5期33卷 1726-1743页

作者： SINGH Hardeep TING David S-K READER Graham ESHTIAGHI nicky ICHIYANAGI Mitsuhisa SUZUKI Takashi Turbulence&Energy Laboratory University of WindsorWindsor N9B 3P4Canada Chemical and Environmental Engineering School of EngineeringRMIT UniversityMelbourneVictoria 3001Australia Department of Engineering and Applied Sciences Sophia UniversityTokyo 102-8554Japan

This research investigates innovative fin-type radiators for automobile engine cooling ***-channel and helical radiators,along with straight type,were analyzed for heat transfer characteristics under various *** uniqueness of this study is evident in the design of microchannel and helical *** helical radiators,the inner rod features 4/8 helical-shaped water galleries,while the outer tube frame with embedded fins remains *** contrast,the microchannel radiators have compact trapezoidal-shaped water galleries with separate fin ***,the novelty of the research is enhanced by the utilization of 3D printing technology in the manufacturing *** constant fin height analysis at varied water and air flow rate,Microchannel Water Air Radiator with fin height 10.5 mm(MCWAR10.5)depicted a higher heat transfer rate amongst the *** comparison to Straight Water Air Radiator with fin height 9.5 mm(SWAR9.5),the heat transfer rate is 30.3%and 1.3 times ***,in constant fin surface area analysis,microchannel radiator(MCWAR3.2)illustrates lower heat dissipation than Helical radiator(HWAR138)but higher than HWAR134 and Straight radiator(SWAR6).The examination of pumping loss indicated that the Micro-channel radiator outperformed helical radiators due to its lower pressure *** average pressure loss for Micro-channel radiators was 0.74 kPa,making it 1.2 times higher than that of a straight radiator(0.62 kPa),indicating a better trade-off.

关键词： heat exchangers multi-channel helical heat exchanger heat transfer 3D printing

Reconstructing seafloor age distributions in lost ocean basins

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Geoscience Frontiers 2021年第2期12卷 769-780页

作者： Simon Williams nicky M.Wright John Cannon Nicolas Flament R.Dietmar Müller Department of Geology Northwest UniversityXi’an710069China State Key Laboratory of Continental Dynamics Northwest UniversityXi’an710069China Research School of Earth Sciences The Australian National UniversityACT2601Australia ARC Centre of Excellence for Climate Extremes The Australian National UniversityACT2601Australia EarthByte Group School of GeosciencesUniversity of SydneyAustralia GeoQuEST Research Centre School of EarthAtmospheric and Life SciencesUniversity of WollongongNorthfields AvenueNSW2522Australia

Reconstructions of past seafloor age make it possible to quantify how plate tectonic forces,surface heat flow,ocean basin volume and global sea level have varied through geological ***,past ocean basins that have now been subducted cannot be uniquely reconstructed,and a significant challenge is how to explore a wide range of possible ***,we investigate possible distributions of seafloor ages from the late Paleozoic to present using published full-plate reconstructions and a new,efficient seafloor age reconstruction workflow,all developed using the open-source software *** test alternative reconstruction models and examine the influence of assumed spreading rates within the Panthalassa Ocean on the reconstructed history of mean seafloor age,oceanic heat flow,and the contribution of ocean basin volume to global sea *** reconstructions suggest variations in mean seafloor age of~15 Myr during the late Paleozoic,similar to the amplitude of variations previously proposed for the Cretaceous to *** reconstructed oceanic age-area distributions are broadly compatible with a scenario in which the long-period fluctuations in global sea level since the late Paleozoic are largely driven by changes in mean seafloor *** suggestions of a constant rate of seafloor production through time can be modelled using our workflow,but require that oceanic plates in the Paleozoic move slower than continents based on current reconstructions of continental motion,which is difficult to reconcile with geodynamic studies.

关键词： Plate reconstructions Sea level Seafloor spreading

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nicky Gavron:伦敦的转变

房地产导刊 2012年第Z1期 52-55页

作者： nicky Gavron 英国大伦敦议会

nicky Gavron分析了伦敦在城市发展中遇到的问题,分享了扭转这一局面的一些措施:建绿化带来阻止城市无章法地蔓延;建高密度的混合功能社区,改善公共交通模式;引导居民使用可持续的建筑和设计;减少碳排放,提高能源使用率;设立气候变化处... 详细信息

nicky Gavron分析了伦敦在城市发展中遇到的问题,分享了扭转这一局面的一些措施:建绿化带来阻止城市无章法地蔓延;建高密度的混合功能社区,改善公共交通模式;引导居民使用可持续的建筑和设计;减少碳排放,提高能源使用率;设立气候变化处;投资公共交通及创新性措施——收取拥堵费等。

关键词：伦敦混合功能创新性 nicky Gavron 投资财政管理高密度交通拥挤公共交通公交

Simple and customizable method for fabrication of high-aspect ratio microneedle molds using low-cost 3D printing

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Microsystems & Nanoengineering 2019年第1期5卷 250-263页

作者： Kevin J.Krieger nicky Bertollo Manita Dangol John T.Sheridan Madeleine M.Lowery Eoin D.O’Cearbhaill UCD Centre for Biomedical Engineering University College DublinBelfieldDublin 4Ireland School of Mechanical&Materials Engineering University College DublinBelfieldDublin 4Ireland School of Electrical&Electronic Engineering University College DublinBelfieldDublin 4Ireland

We present a simple and customizable microneedle mold fabrication technique using a low-cost desktop SLA 3D *** opposed to conventional microneedle fabrication methods,this technique neither requires complex and expensive manufacturing facilities nor expertise in *** most low-cost 3D-printed microneedles to date display low aspect ratios and poor tip sharpness,we show that by introducing a two-step“Print&Fill”mold fabrication method,it is possible to obtain high-aspect ratio sharp needles that are capable of penetrating *** first the effect of varying design input parameters and print settings,it is shown that printed needles are always shorter than *** decreasing input height,needles also begin displaying an increasingly greater than specified needle base *** factors contribute to low aspect ratio needles when attempting to print submillimeter height *** setting input height tall enough,it is possible to print needles with high-aspect ratios and tip radii of 20–40μ*** tip sharpness is smaller than the specified printer ***,high-aspect ratio sharp needle arrays are printed in basins which are backfilled and cured in a second step,leaving sub-millimeter microneedles exposed resulting microneedle arrays which can be used as male *** female master molds are then formed from the fabricated microneedle *** the molds,both carboxymethyl cellulose loaded with rhodamine B as well as polylactic acid microneedle arrays are produced and their quality examined.A skin insertion study is performed to demonstrate the functional capabilities of arrays made from the fabricated *** method can be easily adopted by the microneedle research community for in-house master mold fabrication and parametric optimization of microneedle arrays.

关键词： needle cost printer

SHANGHAI STYLE Fall 2015 THE CITY'S MOST FASHIONABLE MEN

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城市漫步（上海版、英文） 2015年第9期 34-39页

作者： Marianna Cerini nicky Almasy(Photos) 不详

Men and *** some,the concept sounds a bit like an *** two go together like socks and sandals:they rub along,but not comfortably or *** the word fashion is enough to make some guys break out in an unsightly ***’s not the case for everyone though.A few gents out there have their own distinctive and individual ideas about what looks *** Shanghai,they’re a growing *** singers to entrepreneurs,PR gurus to bloggers,a number of men are raising the bar for style in the city,and carrying themselves through the world with confidence and *** are men who can teach you a thing or two about how to get dressed—and whose moves you’ll most want to steal.

关键词： everyone dress enough

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TALES OF THE CITY

城市漫步（上海版、英文） 2016年第6期 8-10页

作者： VIRGINIA WERNER nicky ALMASY 不详

After seven years of construction and an investment of RMB 14.8 billion,the 127-story Shanghai Tower is the newest addition to the Lujiazui *** 632 meters,the world's second tallest building is expected to host tens of thousands of people for both work and play,boasting a hotel,restaurants,swimming pool,museum and art gallery,conference halls and exhibition spaces,offices,and much *** there any reason to even leave the building?

关键词： investment restaurant exhibition