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A new software for automated counting of glistenings in intraocular lenses in vivo

International Journal of Ophthalmology(English edition) 2023年第8期16卷 1237-1242页

作者： nick stanojcic Christopher C.Hull Eduardo Mangieri Nathan Little David O’Brart Department of Ophthalmology Guy’s and St Thomas’NHS Foundation TrustLondon SE17EHUK Centre for Applied Vision Research School of Health SciencesUniversity of LondonLondon EC1V 0HBUK Sparca Ltd CroydonSurrey CR01QQUK King’s College London WC2R 2LSUK

AIM:To assess the performance of a bespoke software for automated counting of intraocular lens(IOL)glistenings in slit-lamp ***:IOL glistenings from slit-lamp-derived digital images were counted manually and automatically by the bespoke *** images of one randomly selected eye from each of 34 participants were used as a training set to determine the threshold setting that gave the best agreement between manual and automatic grading.A second set of 63 images,selected using randomised stratified sampling from 290 images,were used for software *** images were obtained using a previously described ***-derived automated glistenings counts were compared to manual counts produced by three ***:A threshold value of 140 was determined that minimised the total deviation in the number of glistenings for the 34 images in the training *** this threshold value,only slight agreement was found between automated software counts and manual expert counts for the validating set of 63 images(κ=0.104,95%CI,0.040-0.168).Ten images(15.9%)had glistenings counts that agreed between the software and manual *** were 49 images(77.8%)where the software overestimated the number of ***:The low levels of agreement show between an initial release of software used to automatically count glistenings in in vivo slit-lamp images and manual counting indicates that this is a non-trivial *** improvement involving a dialogue between software developers and experienced ophthalmologists is required to optimise *** results suggest that validation of software is necessary for studies involving semi-automatic evaluation of glistenings.

关键词： new software automated counting glistenings intraocular lenses slit-lamp images

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Corneal astigmatic outcomes after femtosecond laser-assisted cataract surgery combined with surface penetrating arcuate keratotomies

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International Journal of Ophthalmology(English edition) 2023年第7期16卷 1084-1092页

作者： nick stanojcic David O’Brart Chris Hull Vijay Wagh Elodie Azan Mani Bhogal Scott Robbie Ji-Peng Olivia Li Department of Ophthalmology Guy’s and St.Thomas’NHS Foundation TrustLondon SE17EHUK Centre for Applied Vision Research School of Health SciencesUniversity of LondonLondon EC1V 0HBUK King’s College London London WC2R 2LSUK

AIM:To evaluate corneal astigmatic outcomes of femtosecond laser-assisted arcuate keratotomies(FAKs)combined with femtosecond-laser assisted cataract surgery(FLACS)over 12mo ***:Totally 145 patients with bilateral cataracts and no ocular co-morbidities were recruited to a singlecentre,single-masked,prospective randomized controlled trial(RCT)comparing two monofocal hydrophobic acrylic intraocular *** with corneal astigmatism(CA)of>0.8 dioptres(D)received unpaired,unopened,surface penetrating FAKs at the time of *** acuity,subjective refraction and Scheimpflug tomography were recorded at 1,6,and *** vectoral analyses were ***:Fifty-one patients(61 eyes),mean age 68.2±9.6y[standard deviation(SD)],received *** eyes were available for analysis,except at 12mo when 59 *** were no complications due to *** pre-operative CA was 1.13±0.20 *** was a reduction of astigmatism at all post-operative visits(residual CA 1mo:0.85±0.42 D,P=0.0001;6mo:0.86±0.35 D,P=0001;and 12mo:0.90±0.39,P=0.0001).Alpins indices remained stable over ***,the cohort was under-corrected at all time *** 12mo,61%of eyes were within±15 degrees of pre-operative astigmatic ***:Unpaired unopened penetrating FAKs combined with on-axis phacoemulsification are safe but minimally *** is largely under-corrected in this cohort using an existing unmodified *** effect of arcuate keratotomies on CA remained stable over 12mo.

关键词： femtosecond cataract surgery astigmatic keratotomy laser cataract surgery femtosecond-laser assisted cataract surgery arcuate keratotomy

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