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A new software for automated counting of glistenings in intraocular lenses in vivo

作     者:Nick Stanojcic Christopher C.Hull Eduardo Mangieri Nathan Little David O’Brart 

作者机构:Department of OphthalmologyGuy’s and St Thomas’NHS Foundation TrustLondon SE17EHUK Centre for Applied Vision ResearchSchool of Health SciencesUniversity of LondonLondon EC1V 0HBUK Sparca LtdCroydonSurrey CR01QQUK King’s CollegeLondon WC2R 2LSUK 

出 版 物:《International Journal of Ophthalmology(English edition)》 (国际眼科杂志(英文版))

年 卷 期:2023年第16卷第8期

页      面:1237-1242页

核心收录:

学科分类:1002[医学-临床医学] 08[工学] 080203[工学-机械设计及理论] 100212[医学-眼科学] 0802[工学-机械工程] 10[医学] 

主  题:new software automated counting glistenings intraocular lenses slit-lamp images 

摘      要:AIM:To assess the performance of a bespoke software for automated counting of intraocular lens(IOL)glistenings in slit-lamp ***:IOL glistenings from slit-lamp-derived digital images were counted manually and automatically by the bespoke *** images of one randomly selected eye from each of 34 participants were used as a training set to determine the threshold setting that gave the best agreement between manual and automatic grading.A second set of 63 images,selected using randomised stratified sampling from 290 images,were used for software *** images were obtained using a previously described ***-derived automated glistenings counts were compared to manual counts produced by three ***:A threshold value of 140 was determined that minimised the total deviation in the number of glistenings for the 34 images in the training *** this threshold value,only slight agreement was found between automated software counts and manual expert counts for the validating set of 63 images(κ=0.104,95%CI,0.040-0.168).Ten images(15.9%)had glistenings counts that agreed between the software and manual *** were 49 images(77.8%)where the software overestimated the number of ***:The low levels of agreement show between an initial release of software used to automatically count glistenings in in vivo slit-lamp images and manual counting indicates that this is a non-trivial *** improvement involving a dialogue between software developers and experienced ophthalmologists is required to optimise *** results suggest that validation of software is necessary for studies involving semi-automatic evaluation of glistenings.

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