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A new software for automated counting of glistenings in intraocular lenses in vivo

International Journal of Ophthalmology(English edition) 2023年第8期16卷 1237-1242页

作者： nic. stanojc.c.c.ristopher c.hull Eduardo Mangieri Nathan Little David O’Brart Department of Ophthalmology Guy’s and St Thomas’NHS Foundation TrustLondon SE17EHUK centre for Applied Vision Research School of Health SciencesUniversity of LondonLondon EC1V 0HBUK Sparca Ltd CroydonSurrey CR01QQUK King’s college London WC2R 2LSUK

AIM:To assess the performance of a bespoke software for automated counting of intraocular lens(IOL)glistenings in slit-lamp ***:IOL glistenings from slit-lamp-derived digital images were counted manually and automatically by the bespoke *** images of one randomly selected eye from each of 34 participants were used as a training set to determine the threshold setting that gave the best agreement between manual and automatic grading.A second set of 63 images,selected using randomised stratified sampling from 290 images,were used for software *** images were obtained using a previously described ***-derived automated glistenings counts were compared to manual counts produced by three ***:A threshold value of 140 was determined that minimised the total deviation in the number of glistenings for the 34 images in the training *** this threshold value,only slight agreement was found between automated software counts and manual expert counts for the validating set of 63 images(κ=0.104,95%cI,0.040-0.168).Ten images(15.9%)had glistenings counts that agreed between the software and manual *** were 49 images(77.8%)where the software overestimated the number of ***:The low levels of agreement show between an initial release of software used to automatically count glistenings in in vivo slit-lamp images and manual counting indicates that this is a non-trivial *** improvement involving a dialogue between software developers and experienced ophthalmologists is required to optimise *** results suggest that validation of software is necessary for studies involving semi-automatic evaluation of glistenings.

关键词： new software automated counting glistenings intraocular lenses slit-lamp images

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Effect of drug therapies on self-reported chemosensory outcomes after cOVID-19

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 88-96页

作者： Marco A.Fornazieri Bruno M.cunha Samuel P.nic.cio Lucas K.Anzolin JoséL.B.da Silva Aristides Fernandes Neto Deusdedit Brandão Neto Richard L.Voegels Fábio D.R.Pinna Department of Surgery Londrina State UniversityLondrinaBrazil Department of Medicine Pontifical Catholic University of ParanáLondrinaBrazil Department of Otorhinolaryngology University of São PauloSao PauloBrazil Department of Otorhinolaryngology:Head and Neck Surgery Perelman School of MedicineSmell and Taste CenterUniversity of PennsylvaniaPhiladelphiaPennsylvaniaUSA

Objective:The aim of this study was to assess the relative efficacy of medications used following severe acute respiratory syndrome coronavirus-2(SARS-coV-2)infection on self-reported alterations in taste and/or smell ***:Seven hundred and fourteen persons with self-reported postcoronavirus disease 2019(post-cOVID-19)chemosensory disorders were personally interviewed regarding specific medications they were administered following the acute phase of the *** dependent measure—self-reported total recovery of chemosensory symptoms—was subjected to stepwise logistic *** predictors included demographic and clinic.l variables,in addition to specific medications used to mitigate disease symptoms(i.e.,systemic corticosteroids,oseltamivir,vitamin c,ibuprofen,hydroxychloroquine,azithromycin,ivermectin,nitazoxanide,anticoagulants,and zinc).Results:The median time between cOVID-19 symptom onset and the interviews was 81 days(interquartile range:60-104).Of the 714 subjects,249(34.9%)reported total recovery of their chemosensory function;437(61.2%)had at least one treatment since the beginning of the *** and those with more comorbidities had undergone more *** recovery rates of the treated and nontreated groups did not differ ***,respondents who had used nitazoxanide tended to have a higher rate of self-reported taste or smell *** who took oral zinc were less likely to ***:No medication employed during the first months after SARS-coV-2 infection had a clear positive effect on returning self-reported smell or taste function to normal,although nitrazoxide trended in a positive *** zinc had a negative effect on the reported recovery of these senses.

关键词： chemosensory disorder coronavirus infections cOVID-19 drug therapy SARS-coV-2 smell loss taste loss

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一种评估非接触水下爆炸对海军复合船体影响的设计方法

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哈尔滨工程大学学报（英文版） 2024年第2期23卷 316-326页

作者： F.Mannacio F.Di Marzo M.Gaiotti c.M.Rizzo M.Venturini Italian Navy Naval Support and Experimentation CentreCSSN Viale S.Bartolomeo40019126 La Spezia(Italy) University of Genova Polytechnic SchoolDITEN Via Montallegro116145 Genova(Italy).

Despite the non-contact underwater explosion phenomena(UNDEX)have been studied for decades and several numerical methods have been proposed in literature,its effects on military structures,especially composite ones,are even nowadays matter of *** early design phases,it is not always possible to verify the shock resistance of hull structures modelling the whole phenomenon,in which fluid,gas and solid properties must be properly set in a fully coupled fluid-structure interaction(FSI)numerical *** ones are extremely complex to set,computationally demanding and certainly not suitable for everyday design *** this paper,a simplified finite element(FE)model,easy to use in an early design phase,is ***,the structure and the fluid are *** this approximation,the fluid behaviour is simplified,using special finite elements,available in a commercial software *** choice reduces the computational time and numerical efforts avoiding the problem of combining computational fluid dynamics(cFD)and FE domains and equations in a fully coupled fluid-structure interaction model.A typical parallel body block of a minesweeper is modelled,using two-dimensional multi-layered shell elements to properly account for the composite materials *** the fluid instead,three dimensional volumetric elements,directly coupled to the structural elements,are *** addition,the same calculation is performed,modelling separately fluid in the cFD environment and structures in the finite element ***,realizing a fully coupled fluid-structure interaction *** results obtained by applying both numerical models are compared with the structural response measured on board of a composite ship during a full-scale shock *** simplified proposed procedure provides results in satisfactory agreement with experiments,allowing the validation of the *** are discussed and differences with the real phenomenon and fully coupled cFD+

关键词： Underwater explosions Shock resistance composites Fluid-structure interaction Experimental analysis Numerical simulation Vulnerability Preliminary design

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Manipulation of polarization topology using a Fabry-Pérot fiber cavity with a higher-order mode optical nanofiber

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Photonic. Research 2023年第6期11卷 1029-1037页

作者： MAKI MAEDA JAMEESH KELOTH SÍLE nic.cHORMAIc Okinawa Institute of Science and Technology Graduate University OnnaOkinawa 904-0495Japan

Optical nanofiber cavity research has mainly focused on the fundamental ***,a Fabry-Pérot fiber cavity with an optical nanofiber supporting the higher-order modes(TE01,TM01,HEo21,and HEe21)is *** cavity spectroscopy,with mode imaging and analysis,we observed cavity resonances that exhibited complex,inhomogeneous states of polarization with topological features containing Stokes singularities such as c-points,Poincarévortices,and *** situ tuning of the intracavity birefringence enabled the desired profile and polarization of the cavity mode to be *** believe these findings open new research possibilities for cold atom manipulation and multimode cavity quantum electrodynamics using the evanescent fields of higher-order mode optical nanofibers.

关键词： polarization fiber optical

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Structural characterization of thin-walled microbubble cavities

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光子学研究:英文版 2023年第8期11卷 I0021-I0027页

作者： MOHAMMED ZIA JALALUDEEN SHILONG LI KE TIAN TOSHIO SASAKI SÍLE nic.cHORMAIc Light-Matter Interactions for Quantum Technologies Unit Okinawa Institute of Science and Technology Graduate UniversityOnnaOkinawa 904-0495Japan college of Physics and Optoelectronic.Engineering Harbin Engineering UniversityHarbin 150001China Scientific Imaging Section Okinawa Institute of Science and Technology Graduate UniversityOnnaOkinawa 904-0495Japan

Whispering gallery mode(WGM)microbubble cavities are a versatile optofluidic sensing platform owing to their hollow core *** increase the light–matter interaction and,thereby,achieve higher sensitivity,thinwalled microbubbles are ***,a lack of knowledge about the precise geometry of hollow microbubbles prevents us from having an accurate theoretical model to describe the WGMs and their response to external *** this work,we provide a complete characterization of the wall structure of a microbubble and propose a theoretical model for the WGMs in this thin-walled microcavity based on the optical waveguide *** characterization of the wavelength-scale wall is enabled by focused ion beam milling and scanning electron microscopy *** proposed theoretical model is verified by finite element method *** approach can readily be extended to other low-dimensional micro-/nanophotonic.structures.

关键词： waveguide characterization bubble

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Options, Futures, and Other Derivatives with Derivagem cD (7th Edition) 7

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丛书名： includes Student Solutions Manual for Options, Futuresd Other Derivatives

2008年

作者： John c. hull

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Options, futures, and other derivatives 6th ed

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2006年

作者： John c. hull

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Options, futures & other derivatives 5th ed

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丛书名： Prentice Hall finance series

2003年

作者： John c. hull

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Spatial density estimate of the snow leopard, Panthera uncia, in the central Tibetan Plateau, china

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Integrative Zoology 2023年第4期18卷 677-687页

作者： Xiaoxing BIAN Xuchang LIANG Byron WEcKWORTH Dorje JYAL Vanessa hull Le YANG School of Natural Resources and Environment University of FloridaGainesvilleUSA Department of Wildlife Ecology and conservation University of FloridaGainesvilleUSA Wildlife conservation Society china BeijingChina Panthera New YorkUSA Tibet Plateau Institute of Biology LhasaChina

Knowledge of large carnivore population abundance is essential for wildlife management and conservation,but these data are often difﬁcult to obtain in inherently low-density *** particular,the snow leopard,Panthera uncia,an enigmatic cat occupying remote mountains in central Asia,has received insufﬁcient assessments of its population abundance because of logistical and methodological ***,we aimed to develop a robust density estimation of snow leopards based on 81 days of camera trapping within a contiguous and previously un-surveyed 1950 km2 area of habitat on the Tibetan Plateau(Mayue Township,Shenzha county,Tibet Autonomous Region,china).By applying spatially explicit capture–recapture models,we produced an estimate of 1.40(95%cI:1.06–1.84)individuals per 100 *** also suggested sex-speciﬁc variation in the range of movement around activity centers,with male(N=10,σ=4.02)movement considerably greater than female(N=8,σ=1.84)***ﬁndings can serve as a reliable baseline reference for assessing the population trends of this endangered felid species with future *** study will provide context to contribute toward a better understanding of ecological factors shaping the distribution and abundance of snow leopards and the related conservation measures needed to sustain their long-term survival on the Tibetan Plateau.

关键词： population density snow leopard spatial capture–recapture Tibetan Plateau

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New interchange English for international ***'s book-第2版 2

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2004年

作者： Jack c. Richards Jonathan hull Susan Proctor

本教程内容包括听、说、读、写四种技能，同时进行语音训练和词汇扩展，尤其强调听说技能的培养。本册(2级)针对有初级英语水平的学习者，旨在进一步培养语法、词汇和语用技能，使学习者达到初高级水平。

ISBN: (纸本)7560021301

关键词：英语

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