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Granulocyte colony-stimulating factor reduces biliary fibrosis and ductular reaction in a mouse model of chronic cholestasis

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Liver Research 2023年第1期7卷 90-98页

作者： Trinh Van Le thanh Minh Dang Huy Quang Do Ai-Xuan Le Holterman Hong-thuy Phan-thi Thong Tan Tran Nhung Hai Truong Laboratory of Stem Cell Research and Application University of Science-VNUHCMHo Chi Minh CityVietnam Vietnam National University Ho Chi Minh CityVietnam Department of Pediatrics and Surgery University of Illinois College of MedicineChicagoILUSA Faculty of Biology and Biotechnology University of Science-VNUHCMHo Chi Minh CityVietnam

Background:Biliary atresia is a rare congenital bile duct disease that is the leading cause of liver fibrosis in *** colony-stimulating factor(GCSF)is a potential therapy for hepatocellular diseases,but data on GCSF for cholestatic conditions remain *** and methods:The current study examines the role of GCSF in improving bile duct obstruction in *** doses were administered:10.0 mg/kg/day and 61.5 mg/kg/day,which is the animal equivalent dose of 5.0 mg/kg in *** days(D7)after bile duct ligation(BDL),Swiss mice were treated with phosphate buffered saline or GCSF for 5 *** intrahepatic adaptive response of BDL mice was evaluated on postsurgical days D12,D19,and ***:Treatment with 61.5 mg/kg of GCSF resulted in a significant increase in circulating leukocytes and neutrophils on *** of liver injury,as shown by reduced aspartate aminotransferase levels,increased albumin levels and survival rate,as well as reduced intrahepatic inflammation and hepatic myeloperoxidase expression,downregulated ductular proliferation,periportal fibroblast activation,and fibrosis,enhanced expressions of hepatocyte growth factor,peroxisome proliferator-activated receptoralpha,and ki67,and suppressed expression of cleaved caspase-3 protein,was noted after treatment with 61.5 mg/kg of ***,GCSF treatment was associated with an increased number of intrahepatic cd3-Sca1tc-Kitt bone marrow cells.

关键词： Bile duct ligation(BDL) Biliary fibrosis Ductular reaction Granulocyte colony-stimulating factor(GCSF) Hepatic stellate cell(HSC)

A Novel Incremental Attribute Reduction Algorithm Based on Intuitionistic Fuzzy Partition Distance

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Computer Systems Science & Engineering 2023年第12期47卷 2971-2988页

作者： Pham Viet Anh nguyen Ngoc thuy nguyen Long Giang Pham Dinh Khanh nguyen The thuy Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoi100000Vietnam Institute of Information Technology Vietnam Academy of Science and TechnologyHanoi100000Vietnam HaUI Institute of Technology Hanoi University of IndustryHanoi100000Vietnam Faculty of Information Technology University of SciencesHue UniversityHue530000Vietnam AI Research Department Neurond Technology JSCHanoi100000Vietnam Information and Communication Technology Center Department of Information and CommunicationsBacninh790000Vietnam

Attribute reduction,also known as feature selection,for decision information systems is one of the most pivotal issues in machine learning and data *** based on the rough set theory and some extensions were proved to be efficient for dealing with the problemof attribute ***,the intuitionistic fuzzy sets based methods have not received much interest,while these methods are well-known as a very powerful approach to noisy decision tables,i.e.,data tables with the low initial classification ***,this paper provides a novel incremental attribute reductionmethod to dealmore effectivelywith noisy decision tables,especially for highdimensional *** particular,we define a new reduct and then design an original attribute reduction method based on the distance measure between two intuitionistic fuzzy *** should be noted that the intuitionistic fuzzypartitiondistance iswell-knownas aneffectivemeasure todetermine important *** interestingly,an incremental formula is also developed to quickly compute the intuitionistic fuzzy partition distance in case when the decision table increases in the number of *** formula is then applied to construct an incremental attribute reduction algorithm for handling such dynamic ***,some experiments are conducted on real datasets to show that our method is far superior to the fuzzy rough set based methods in terms of the size of reduct and the classification accuracy.

关键词： Incremental attribute reduction intuitionistic fuzzy sets partition distance measure dynamic decision tables

An improved CRNN for Vietnamese Identity Card Information Recognition

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Computer Systems Science & Engineering 2022年第2期40卷 539-555页

作者： Trinh Tan Dat Le Tran Anh Dang nguyen Nhat Truong Pham Cung Le thien Vu Vu Ngoc thanh Sang Pham thi Vuong Pham The Bao Information Science Faculty Sai Gon UniversityHCM City700000Vietnam Faculty of Electrical&Electronics Engineering University of TechnologyHCM City700000Vietnam

this paper proposes an enhancement of an automatic text recognition system for extracting information from the front side of the Vietnamese citizen identity(CID)***,we apply Mask-RCNN to segment and align the CID card from the ***,we present two approaches to detect the CID card’s text lines using traditional image processing techniques compared to the EAST ***,we introduce a new end-to-end Convolutional Recurrent Neural Network(CRNN)model based on a combination of Connectionist Temporal Classification(CTC)and attention mechanism for Vietnamese text recognition by jointly train the CTC and attention objective functions *** length of the CTC’s output label sequence is applied to the attention-based decoder prediction to make the final label *** process helps to decrease irregular alignments and speed up the label sequence estimation during training and inference,instead of only relying on a data-driven attention-based encoder-decoder to estimate the label sequence in long *** may directly learn the proposed model from a sequence of words without detailed *** evaluate the proposed system using a real collected Vietnamese CID card dataset and find that our method provides a 4.28%in WER and outperforms the common techniques.

关键词： Vietnamese text recognition OCR CRNN BLSTM attention mechanism joint CTC-Attention

ON A NONLINEAR VOLTERRA-HAMMERSTEIN INTEGRAL EQUATION IN TWO VARIABLES

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Acta Mathematica Scientia 2013年第2期33卷 484-494页

作者： Le thi Phuong Ngoc nguyen thanh Long Nhatrang Educational College 01 Nguyen Chanh Str.Nhatrang CityVietnam Department of Mathematics and Computer Science University of Natural ScienceVietnam National University Ho Chi Minh City227 Nguyen Van Cu Str.Dist. 5Ho Chi Minh CityVietnam

Using a fixed point theorem of Krasnosel＇skii type, this article proves the exis- tence of asymptotically stable solutions for a Volterra-Hammerstein integral equation in two variables.

关键词： Volterra-Hamnmrstein integral equation in two variables the fixed point theo-rem of Krasnosel'skii type contraction mapping completely continuous asymp-totically stable solution

Assessment of Livelihood Vulnerability to Drought: A Case Study in Dak Nong Province, Vietnam

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International Journal of Disaster Risk Science 2019年第4期10卷 604-615页

作者： nguyen thi thanh Thao Dao nguyen Khoi Tran thanh Xuan Bernard Tychon Universite de Liege 6700 ArlonBelgium Institute for Environmental Science Engineeringand ManagementIndustrial University of Ho Chi Minh CityHo Chi Minh CityVietnam Institute of Research and Development Duy Tan UniversityDa NangVietnam Faculty of Environment University of ScienceVietnam National University Ho Chi Minh CityHo Chi Minh CityVietnam NTT Institute of Hi-Technology Nguyen Tat Thanh UniversityHo Chi Minh CityVietnam

In recent years,droughts have strongly affected the Central Highlands of Vietnam and have resulted in crop damage,yield decline,and serious water *** study investigated the livelihood vulnerability of five communities of farmers who are exposed to droughts in one of the more vulnerable regions of Vietnam—Dak Nong Province.A survey of 250 households was conducted in the five communities to collect data on the region’s sociodemographic profile,livelihood systems,social networks,health status,food and water security,drought conditions,and climate *** were aggregated using a livelihood vulnerability index and the IPCC vulnerability *** survey results indicate that Quang Phu community is the most vulnerable of the study’s communities,followed by Nam N’dir,Dak Nang,Duc Xuyen,and Dak D’ro in descending order of *** availability and livelihood strategies are the most important variables in determining the vulnerability of the five surveyed *** order to reduce vulnerability to droughts,water management practices and livelihood diversification in farming and nonfarming activities are recommended for the study area.

关键词： Agricultural drought Livelihood vulnerability Vietnam Vulnerability indicators

Fuzzy Multi-Criteria Decision Making for Solar Power Plant Location Selection

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Computers, Materials & Continua 2022年第9期72卷 4853-4865页

作者： Thai Hoang Tuyet Nhi Chia-Nan Wang nguyen Van thanh Department of Industrial Engineering National Kaohsiung University of Science and Technology80778Taiwan Faculty of Commerce Van Lang UniversityHo Chi Minh CityVietnam

Vietnam is one of Southeast Asian countries with a rapid GDP growth rate,ranging from 6.5%to 7%annually,leading to an average increase in energy demand of 11%per *** demand creates many new opportunities in the energy industry,especially renewable energy,to ensure sustainable development in the future for the country with applications of solar energy growing at the present,and other opportunities to expand in the *** Vietnam,thanks to favorable weather,climate,terrain characteristics and many preferential support policies,there are many great opportunities in the field of solar energy exploitation and *** selection is an important problem in all renewable energy ***,the author proposed a fuzzy Multi-criteria Decision-Making Model(MCDM)model for solar power plant location selection in this study,and as a result,location 5 is the optimal *** contribution of this study is to propose a MCDM for solar power plant location selection in Vietnam under fuzzy environmental conditions.

关键词： Solar power multi-decision topsis fanp fuzzy theory

Supplier Selection Fuzzy Model in Supply Chain Management:Vietnamese Cafe Industry Case

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Computers, Materials & Continua 2022年第8期72卷 2291-2304页

作者： Chia-Nan Wang Hoang Tuyet Nhi Thai nguyen Van thanh Department of Industrial Engineering and Management National Kaohsiung University of Science and Technology80778Taiwan Faculty of Commerce Van Lang UniversityHo Chi Minh CityVietnam

Supplier selection is a vital part of the supply chain and is also a current issue that concerns businesses today as supplier quality directly affects the operations of the *** the right supplier can help businesses increase productivity,competitiveness in the market,and profits without having to lower the quality of the ***,choosing a supplier is not a simple matter,it requires businesses to consider many aspects about their ***,the goal of this study is to propose an integrated model consisting of two models:Fuzzy Analytics Network Process(Fuzzy-ANP)model and Weighted Aggregated Sum Product Assessment(WASPAS)to solve the problem *** Fuzzy-ANP model was developed to evaluate the weightings of the supplier selection criteria,and the WASPAS Model was used to rank the *** example of supplier selection in the coffee industry in Vietnam was studied to validate the model,namely 5 main criteria,with 16 sub-criteria,and 7 *** model test results show that the Fuzzy ANP and WASPAS integration model was *** future,these developing models can apply to other industries or integrate with other models.

关键词： Fuzzy-ANP WASPAS multi-decision caféindustry supplier selection supply chain management

The Roles of Female Involvement and Risk Aversion in Open Access Publishing Patterns in Vietnamese Social Sciences and Humanities

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Journal of Data and Information Science 2022年第1期7卷 76-96页

作者： Minh-Hoang nguyen Huyen thanh thanh nguyen Manh-Toan Ho Tam-Tri Le Quan-Hoang Vuong Centre for Interdisciplinary Social Research Phenikaa UniversityYen Nghia WardHa Dong DistrictHanoi 100803Vietnam

Purpose:The open-access(OA)publishing model can help improve researchers’outreach,thanks to its accessibility and visibility to the ***,the presentation of female researchers can benefit from the O A publishing *** that,little is known about how gender affects OA ***,the current study explores the effects of female involvement and risk aversion on OA publishing patterns among Vietname se social sciences and ***/methodology/approach:The study employed Bayesian Mindsponge Framework(BMF)on a dataset of 3,122 Vietnamese social sciences and humanities(SS&H)publications during *** Mindsponge mechanism was specifically used to construct theoretical models,while Bayesian inference was utilized for fitting ***:The result showed a positive association between female participation and OA publishing ***,the positive effect of female involvement on OA publishing probability was negated by the high ratio of female researchers in a *** status was negatively associated with the JIF of the journal in which the publication was published,but the relationship was moderated by the involvement of a female researcher(s).The findings suggested that Vietnamese female researchers might be more likely to publish under the OA model in journals with high JIF for avoiding the risk of public *** limitations:The study could only provide evidence on the association between female involvement and OA publishing ***,whether to publish under OA terms is often determined by the first or corresponding authors,but not necessarily *** implications:Systematically coordinated actions are suggested to better support women and promote the OA movement in ***/value:The findings show the OA publishing patterns of female researchers in Vietnamese SS&H.

关键词： Open science Gender inequality Risk-aversion Vietnam Bayesian analysis

In vivo anticancer activity of maesopsin 4—O— β—glucoside isolated from leaves of Artocarpus tonkinensis *** Gagnep

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Asian Pacific Journal of Tropical Medicine 2016年第4期9卷 343-348页

作者： Trinh thi thuy Dao Duc thien Tran Quang Hung nguyen thanh Tam nguyen thi Hoang Anh nguyen thi Nga nguyen thi Cuc Le Phuong Mai Tran Van Sung Domenico V.Delfino Do thi Thao Institute of Chemistry.Vietnam Academy of Science and Technology Institute of Biotechnology Vietnam Academy of Science and Technology National Research Council Canada Measurement Science and Standards1200 Montreal RoadBuilding M-12.Ottatca.Ontario KIA OR6 Department of Medicine University of PerugiaPiazzale Gambuli.S.Andrea delle Fratte

Objective:To investigate the antitumor effect of maesopsin 4-O-β-glucoside(TAT2) isolated from the leaves of Artocarpus tonkinensis(***) *** ***:The antitumor activity of TAT2 was evaluated in Lewis lung carcinoma(LLC) tumor-bearing ***/c mice had tumors induced by implantation with 2× 10~6 LLC cells into the subcutaneous right posterior ***-bearing mice were treated orally with a range of doses of TAT2 and a standard drug,*** were observed for tumor growth and mortality *** was collected to determine hematological and biochemical *** TAT2 was isolated from an ethanolic extract of *** *** structure was determined by MS and NMR spectroscopy,and identified as *** compound did not show acute toxicity at the highest dose tested(2 OIK) mg/kg body weight).TAT2 exhibited antitumor activity by decreasing tumor growth,increasing the survival rale,and ameliorating some hematological and biochemical parameters at doses of 100 and 200 mg/kg body weight(P<0.05).Conclusions:These results indicate that TAT2 possesses clear antitumor *** to its bioavailability and low toxicity,and the fact that it could be isolated in a large scale from *** leaves,the compound shows promise as a potential anticancer drug.

关键词： Artocarpus tonkinensis BALB/c Hematological parameters Lewis lung carcinoma Maesopsin 4-0-β-glucoside