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Myo-inositol versus metformin effects on clinical features, endocrine and metabolic profiles in infertile women with polycystic ovary syndrome: A randomized controlled trial

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Asian pacific Journal of Reproduction 2023年第6期12卷 256-265页

作者： nguyen Sa Viet Le minh Tam Le Thanh ngoc Cao Center for OBGYN Hue Central Hospital16 Le Loi StreetHueVietnam Center for Reproductive Endocrinology and Infertility Hue University of Medicine and PharmacyHue University06 Ngo Quyen StreetHueVietnam

Objective:To compare the effectiveness of inositol and metformin on the clinical characteristics,and endocrine and metabolic profiles of infertile polycystic ovarian syndrome(PCOS)women from ***:From June 2018 to August 2022,a randomized trial was undertaken at the Hue Center for Endocrinology and Reproduction on infertile women aged 18 to 40 years with polycystic ovarian *** clinical,endocrine,and metabolic features of these individuals were assessed before and after 3 months of treatment with 2 g of inositol or 1700 mg of metformin per *** pregnancy rates,adverse effects,and tolerance of inositol were ***:The study included 171 infertile PCOS women who were eligible to participate and took part in the baseline assessment,of whom 132 women participated in data analysis after 3 *** metformin treatment,42.1%of women with oligomenorrhea experienced regular *** significantly lowered body mass index(BMI),waist circumference and testosterone levels,but had no effect on other clinical characteristics,endocrine profiles,or metabolic profiles.29.2%Of women reported experiencing side effects.21%Of them attained pregnancy,which resulted in 17.1%of live *** the inositol group,the rate of regular cycle increased by 18.2%and the total testosterone concentration significantly *** overweight/obese women with PCOS,inositol significantly decreased weight,BMI,waist and hip circumferences(P<0.05).100%Of women tolerated inositol and continued treatment.18.9%Of them became pregnant,leading to 17%of live ***:Metformin and inositol can improve weight and waist circumference in overweight/obese infertile women with *** is associated with a higher rate of regular menstruation,whereas inositol is associated with a lower rate of adverse *** spontaneous conception,clinical pregnancy,and live birth rates between two groups are comparable.

关键词： Polycystic ovarian syndrome Inositol Metformin Endocrine Metabolic Menstrual cycle Pregnancy

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Spectral properties of the surface reflectance of the northern polar region of Mercury

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Research in Astronomy and Astrophysics 2020年第3期20卷 92-107页

作者： nguyen Bich ngoc Nicolas Bott Pham ngoc Diep Department of Astrophysics Vietnam National Space CenterVietnam Academy of Science and Technology18 Hoang Quoc VietCau GiayHanoiVietnam Laboratoire d'Etudes Spatiales et d' Instrumentation en Astrophysique l'Observatoire de Paris5 place Jules Janssen 92195 MeudonFrance

We analyze MESSENGER reflectance measurements covering the northern polar region of Mercury,the least studied region of the northern mercurian *** use observations from the Mercury Dual Imaging System Wide-Angle Camera(MDIS/WAC)and the Mercury Atmospheric and Surface Composition Spectrometer(MASCS/VIRS)to study the spectral dependence of the surface *** results obtained from the observations made by both instruments are remarkably *** find that a second degree polynomial description of the measured reflectance spectra gives very good fits to the data and that the information that they carry can best be characterized by two parameters,the mean reflectance and the mean relative spectral slope,averaged over the explored range of *** properties of the four main types of terrains known to form Mercury’s regolith in the northern region,smooth plains(SPs),heavily cratered terrain(HCT),fresh ejecta/materials and red pitted ground(RPG),are examined in terms of these two *** results are compared,and found consistent with those obtained by earlier studies in spite of difficulties met in obtaining accurate reflectance measurements under the large incidence angle condition characteristic of polar *** results will help with the preparation of the BepiColombo mission and with supporting its observational strategy.

关键词： planets and satellites terrestrial planets-planets and satellites surfaces-techniques spectroscopic

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Contour blasting parameters by using a tunnel blast design mode

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Journal of Central South University 2021年第1期28卷 100-111页

作者： nguyen ngoc minh CAO Ping LIU Zhi-zhen School of Resources and Safety Engineering Central South UniversityChangsha 410083China Quang Ninh University of Industry Quang Ninh 208650Vietnam

The quality of contour blasting depends on many initial blasting *** parameters including blasthole diameter,rock Protodyakonov coefficient,tunnel area and distance between cracks on the tunnel face are more *** this study,an algorithm linking between Delphi programming language and AutoCAD was created to develop a tunnel blasting *** this model,tunnel contour blasting passport in AutoCAD can be obtained *** effects of rock Protodyakonov coefficient and cracks’distance on blastholes number and specific charge with the variation of blasthole diameter and the semi-circular tunnel face area were investigated to yield a set of equations with the highest *** results show that specific charge increases as rock Protodyakonov coefficient,cracks’distance and drillhole diameter increase,but decreases when tunnel face area *** addition,the number of drillholes increases linearly as tunnel face area increases but decreases when drillhole diameter increases.

关键词： contour blasting blasting model blasting passport tunnel blasting

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Effect of Poly-Alkylene-Glycol Quenchant on the Distortion, Hardness, and Microstructure of 65Mn Steel

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Computers, Materials & Continua 2021年第6期67卷 3249-3264页

作者： Thi Xuan Tran Xuan phuong nguyen Duong Nam nguyen Dinh Toai Vu minh Quang Chau Osamah Ibrahim Khalaf Anh Tuan Hoang Hanoi University of Science and Technology HanoiVietnam Ho Chi minh City University of Transport Ho Chi Minh CityVietnam Vietnam Maritime University HaiphongVietnam Industrial University of Ho Chi minh City(IUH) Ho Chi Minh CityVietnam Al-Nahrain Nanorenewable Energy Research Center Al-Nahrain UniversityBaghdadIraq Ho Chi minh city University of Technology(HUTECH) Ho Chi Minh CityVietnam

Currently,the 65Mn steel is quenched mainly by oil *** though the lower cooling rate of oil compared to water reduces the hardness of steel post quenching,the deforming and cracking of parts are often *** the other hand,the oil media also has the disadvantage of being ammable,creating smoke that adversely affects the *** poly alkylene glycol(PAG)polymer quenchant is commonly used for quenching a variety of steels based on its advantages such as non-ammability and exible cooling rate subjected to varying concentration and stirring *** article examines the effect of PAG polymer quenching solution(with concentrations of 10%and 20%)on deformation,hardness,and microstructure of C-ring samples made of 65Mn ***,the performance of PAG polymer quenchant is also compared with those of two common quenching solutions:Water and *** cooling in water,the C-ring samples had the largest deformation and 2 times higher than the results obtained when a 10%PAG solution was *** particular,similar levels of deformation on the C-ring samples were observed in both cases of 20%PAG solution and oil as the primary quenching ***,the hardness level measured between the sampled parts quenched in the 20%PAG solution appeared to be more uniform than that obtained from the oil-quenched *** study of the microscopic structure of steel by optical microscopy combined with X-ray diffraction showed that the water hardened sample exhibited cracks and comprised of two phases,martensite and retained *** to the results of Electron Back Scattering Diffraction(EBSD)analysis and backscattering electronic image(BSE),the content of austenite residue in the sample when the sample was cooled in PAG 10 and 20%solution was 3.21%and 4.73%,respectively and smaller than the measurements obtained from oil quenching ***,the 65Mn steel is cooled in 20%PAG solution for high hardness and more evenly distributed than when it is q

关键词： Polyethylene glycol electron backscattering diffraction quenching media cooling rate backscattering electronic image

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Antidiabetic and antioxidant activities of red seaweed Laurencia dendroidea

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Asian Pacific Journal of Tropical Biomedicine 2019年第12期9卷 501-509页

作者： The Han nguyen Thi Huyen nguyen Van minh nguyen Thi Lan phuong nguyen Thi Van Anh Tran Anh Duy Do Sang Moo Kim Faculty of Food Technology Nha Trang University02 Nguyen Dinh Chieu StreetNha Trang CityKhanh HoaVietnam Quality Control Department Institute of Vaccines and Medical BiologicalsNha Trang CityKhanh HoaVietnam Faculty of Pharmacy University of Medicine and Pharmacy of Ho Chi Minh City41 Dinh Tien Hoang StreetHo Chi Minh CityVietnam Research Department of Marine Conservation Research Institute for Marine Fisheries224 Le Lai StreetHai Phong CityVietnam Department of Marine Food Science and Technology Gangneung-Wonju National University7 Jukheon-gilGangneung 25457Republic of Korea

Objective:To investigate antidiabetic and antioxidant activities of the extract and fractions from Vietnamese red seaweed Laurencia ***:The seaweed Laurencia dendroidea was extracted by using microwave-assisted extraction method in 80%*** seaweed extract was then fractionated using different solvents(n-hexane,chloroform,ethyl acetate,butanol and water).These obtained fractions were evaluated forα-glucosidase inhibitory and antioxidant *** activities were tested using DPPH,nitric oxide radical scavenging and metal chelating *** enzyme inhibition mode was determined using Lineweaver-Burk *** acidic and thermal stabilities,the ethyl acetate fraction was treated at pH 2.0 and 100℃,*** residual inhibitory activity of the fraction was calculated based on the initial inhibitory *** in vivo antidiabetic activity,mice were divided into four groups,including normal control,diabetic control,diabetic mice treated with ethyl acetate fraction and diabetic mice treated with *** glucose level of treated mice during acute and prolonged treatments was *** evaluate the toxicity of the ethyl acetate fraction,the body weight changes and activities of liver function enzymes(aspartate transaminase,alanine transaminase and gammaglutamyl transferase)were carried ***:The extract of Laurencia dendroidea showed strongα-glucosidase inhibitory and DPPH radical scavenging *** concentrations affected bothα-glucosidase inhibitory and antioxidant activities.A 80%aqueous methanol was the suitable solvent for extraction of enzyme inhibitors and *** solvent fractions,ethyl acetate fraction had the highest inhibitory activities againstα-glucosidase with a mixed type of inhibition and the strongest antioxidant activities,and was stable under acidic and thermal *** ethyl acetate fraction treated diabetic mice significantly reduced blood glucose level compare

关键词： α-Glucosidase inhibitor Antidiabetic Antioxidant Red seaweeds Vietnam

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Electronic Band Structure of Carbon Nanotubes with Kekule Structure

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Chinese Physics Letters 2013年第9期30卷 97-100页

作者： nguyen ngoc Hieu Le Cong Nhan Center of Research and Development Duy Tan UniversityK7/25 Quang TrungDa NangViet Nam Department of Environmental Science Saigon University273 An Duong VuongHo Chi Minh cityViet Nam

Electronic band structure of carbon nanotubes with the Kekule structure is studied by the tight-binding *** give a complete geometrical approach to structural properties of carbon nanotubes with bond alternation,including chiral and achiral *** the Kekule is introduced,all carbon nanotubes become semiconducting with a small band gap at the Fermi *** band gap of the carbon nanotubes depends only on the difference between C–C bond lengths or the resonance integrals.

关键词： carbon structure Fermi

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Ethyl acetate extract of Smilax glabra Roxb roots and its major active compound astilbin promote osteoblastogenesis in vitro by upregulating bone cell differentiation-associated genes

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Asian Pacific Journal of Tropical Biomedicine 2021年第12期11卷 553-560页

作者： Huyen T.T.nguyen minh T.H.nguyen Thu X.nguyen Quan M.Pham Ha X.nguyen phuong T.M.nguyen University of Science and Technology of Hanoi Vietnam Academy of Science and TechnologyHanoiVietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoiVietnam Institute of Natural Products Chemistry Vietnam Academy of Science and TechnologyHanoiVietnam Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoiVietnam

Objective:To investigate the osteoblastogenic activity of the ethyl acetate(EtOAc)extract of Smilax glabra Roxb roots and its major active compound ***:Astilbin was isolated from EtOAc extract using silica gel chromatography combined with fraction *** structure of astilbin was determined by analysis of the spectroscopic data in comparison with the *** method was used to detect the *** phosphatase(ALP)activity was determined by the spectrophotometric method at 405 nm using p-nitrophenyl phosphate as a *** deposition was stained with alizarin red-S,distained with cetylpyridium chloride,and quantified at 562 *** silico model for astilbin-ALP interaction was analyzed using AutoDock *** changes in expression of osteoblast differentiation related genes were determined using quantitative real-time ***:Both the EtOAc extract and astilbin had no toxicity toward osteoblast MC3T3-E1 cells at 5.0,10,25,and 50μg/*** 25μg/mL,they enhanced ALP activity and mineralization of osteoblasts up to 30%and 55%for the EtOAc extract and 22%and 41%for astilbin,*** docking analysis of astilbin-ALP interaction revealed Arg167,Asp320,His324,and His437 were key residues participating in hydrophobic interaction;meanwhile,His434 and Thr436 residues were involved in hydrogen bond formation in the active site of human tissue-nonspecific ***,the expression level of genes opn,col1,osx,and runx2 were up-regulated in astilbin treated samples with the fold changes as 2.2;3.7;4.1;2.3,respectively at 10μg/mL(P<0.05).Conclusions:The EtOAc extract and its major compound astilbin exhibit osteoblastogenic activity by up-regulating important markers for bone cell *** could be a new and promising osteogenic agent with dual actions for therapeutic applications.

关键词： Smilax glabra Roxb Astilbin Cytotoxicity Osteogenesis Osteoblast Ethyl acetate extract

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A Multinational Data Set of Game Players' Behaviors in a Virtual World and Environmental Perceptions

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Data Intelligence 2021年第4期3卷 606-629页

作者： Quan-Hoang Vuong Manh-Toan Ho Viet-phuong La Tam-Tri Le Thanh Huyen T.nguyen minh-Hoang nguyen Centre for Interdisciplinary Social Research Phenikaa UniversityYen Nghia WardHa Dong DistrictHanoi 100803Vietnam A.I.for Social Data Lab Vuong&AssociatesDong Da DistrictHanoi 100000Vietnam

Video gaming has been rising rapidly to become one of the primary entertainment media,especially during the COVID-19 *** video games has been reported to associate with many psychological and behavioral ***,little is known about the connections between game players’behaviors in the virtual environment and environmental ***,the current data set offers valuable resources regarding environmental worldviews and behaviors in the virtual world of 640 Animal Crossing:New Horizons(ACNH)game players from 29 countries around the *** data set consists of six major categories:1)socio-demographic profile,2)COVID-19 concern,3)environmental perception,4)gameplaying habit,5)in-game behavior,and 6)game-playing *** making this data set open,we aim to provide policymakers,game producers,and researchers with valuable resources for understanding the interactions between behaviors in the virtual world and environmental perceptions,which could help produce video games in compliance with the United Nations(UN)Sustainable Development Goals.

关键词： Environmental psychology Virtual environment Game-playing behaviors Multinational UN compliance design

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Revealing efficient catalytic performance of N-CuO_(x) for aerobic oxidative coupling of aliphatic alkynes:A Langmuir-Hinshelwood reaction mechanism

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Nano Research 2022年第7期15卷 6076-6083页

作者： Jun Tang Bowen Jiao Wei Chen Fei Ruan Fengfeng Li Peixin Cui Chao Wan minh ngoc Ha Van Noi nguyen Qingping Ke College of Chemistry and Chemical Engineering Anhui University of TechnologyMaanshan 243002China Key Laboratory of Carbon Materials of Zhejiang Province College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325035China Key Laboratory of Soil Environment and Pollution Remediation Institute of Soil Sciencethe Chinese Academy of SciencesNanjing 210008China VNU Key Laboratory of Advanced Material for Green Growth VNU University of ScienceVietnam National UniversityHanoi 100000Vietnam

O_(x)idative couplings of aliphatic alkynes are crucial for the production of naturally occurring 1,*** we report the novel approach for effective synthesis of unsaturated coordinated N doped copper oxides(N-CuO_(x))catalyst,and uncover that N-CuO_(x) catalyst as an additive-free and cost-effective heterogeneous catalyst has highly catalytic performance for directly oxidative coupling of aliphatic *** key to achieve efficient oxidative coupling of aliphatic alkynes is the synergistic effect of N species and uncoordinated O/Cu species caused by N dopants,which undergoes the Langmuir–Hinshelwood reaction *** N-CuO_(x) catalyst displays~89.1%yield for hexadeca-7,9-diyne under mild conditions and stable reusability(5 cycles),showing significant advances compared with the traditionally copper *** findings highlight the heteroatom dopants that provide a new methodology for designing efficient copper catalysts in synthesis of naturally occurring 1,3-diynes.

关键词： N doped copper oxides(N-CuO_(x)) straight chain alkynes homo-coupling additive-free 1,3-diynes

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ON BOUNDEDNESS PROPERTY OF SINGULAR INTEGRAL OPERATORS ASSOCIATED TO A SCHRODINGER OPERATOR IN A GENERALIZED MORREY SPACE AND APPLICATIONS

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Acta Mathematica Scientia 2020年第5期40卷 1171-1184页

作者： Xuan Truong LE Thanh Nhan nguyen ngoc Trong nguyen Division of Computational Mathematics and Engineering Institute for Computational ScienceTon Due Thang UniversityHo Chi Minh CityVietnam Faculty of Mathematics and Statistics Ton Due Thang UniversityHo Chi Minh CityVietnam Department of Mathematics Ho Chi Minh City University of EducationHo Chi Minh CityVietnam Department of Primary Education Ho Chi Minh City University of EducationHo Chi Minh CityVietnam

In this paper,we provide the boundedness property of the Riesz transforms associated to the Schrodinger operator■=-Δ+V in a new weighted Morrey space which is the generalized version of many previous Morrey type *** additional potential V considered in this paper is a non-negative function satisfying the suitable reverse Holder's *** results are new and general in many cases of *** an application of the boundedness property of these singular integral operators,we obtain some regularity results of solutions to Schrodinger equations in the new Morrey space.

关键词： weighted Morrey spaces Schodinger operator riesz transforms Regularity estima tes

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