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A numerical model to simulate the transient frictional viscoelastic sliding contact

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Friction 2024年第2期12卷 319-339页

作者： Dongze WANG Gregory de BOER Anne neville Ali GHANBARZADEH School of Mechanical Engineering University of LeedsLeeds LS29JTUK

Sliding motion has always been one of the major concerns when it comes to the analysis of viscoelastic contact problems.A new model simulating the transient sliding contact of smooth viscoelastic surfaces is developed in this *** taking the dry contact friction and the coupling between shear tractions and normal pressure into account,the effect of the early partial slip period,which is often neglected in the study of viscoelastic sliding contact problems,is investigated *** with solutions based on the frictionless assumption,the steady-state pressure profile is found to be slightly different under the effect of the partial slip regime,including a lower peak pressure and the shift of the contacting region in the direction opposite to the sliding ***,the time required for the viscoelastic contact to reach its steady state is delayed owing to the partial slip period preceding the global sliding motion.

关键词： contact mechanics frictional sliding viscoelasticity viscoelastic friction

Mitochondrial therapeutics and mitochondrial transfer for neurodegenerative diseases and aging

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Neural Regeneration Research 2025年第3期20卷 794-796页

作者： neville Ng Michelle Newbery Nicole Miles Lezanne Ooi Molecular Horizons and School of Chemistry and Molecular Bioscience University of WollongongWollongongNSWAustralia

Mitochondrial dysfunction and neurodegeneration:Progressive neurodegenerative diseases affect a significant proportion of the population;in a single year,there are as many as 276 million disabilities and 9 million dea... 详细信息

关键词： degenerative diseases Mitochondrial

Amyloid pores in mitochondrial membranes

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Neural Regeneration Research 2021年第11期16卷 2225-2226页

作者： neville Vassallo Department of Physiology&Biochemistry Faculty of Medicine and SurgeryUniversity of MaltaMsida MSD 2080Malta

Neurodegenerative diseases of the amyloid type include common conditions such as Alzheimer’s disease,Parkinson’s disease,Huntington’s disease and amyotrophic lateral *** the fact that the phenotypes of these neuropathic maladies differ widely,ranging from cognitive to motor and psychotic disturbances,they are all characterized by the pathological accumulation and deposition in the central nervous system of well-ordered protein aggregates known as amyloid *** evidence indicates that rather than the end-stage mature fibrils,however,it is the smaller,metastable intermediate forms(known as oligomers)of the aggregated protein and peptides which represent the most neurotoxic species(Chiti and Dobson,2017).One suggested mechanism for such toxicity appears to involve the ability of oligomers to interact with plasma membranes whilst inducing cell leakage(Surguchov et al.,2017).However,contemporary work increasingly points to mitochondria,and hence mitochondrial membranes,as preferential targets for the pathogenic action of oligomers in the neuronal cell(Ghio et al.,2016).

关键词： Huntington membranes amyloid

Behavioral interactions between a coexisting rodent Micaelamys namaquensis and macroscelid Elephantulus myurus

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Current Zoology 2010年第4期56卷 395-400页

作者： Jennifer LANCASTER neville PILLAY School of Animal Plant and Environmental Sciences University of the Witwatersrand

A number of mechanisms are known to influence coexistence in small mammal communities. However, the role ofbehavioral interactions in promoting species coexistence is under-represented in the literature. We studied the behavioral interactionsof two coexisting small mammals, the Namaqua rock mouse Micaelamys namaquensis (Rodentia) and the Rock sengi Elephantulusmyurus (Macroscelidae), which have high dietary and microhabitat overlap. Using wild-caught individuals, intra- andinterspecific dyadic encounters were staged in tanks on a neutral rocky outcrop. Interspecific dyads displayed significantly moreactive avoidance behavior. There was no support for the prediction that the larger, more specialist species, E. myurus, is behaviorallydominant over M. namaquensis. Intraspecific encounters of E. myurus showed significantly more passive avoidance andamicable behavior, whereas the behavior of M. namaquensis did not differ between intra- and inter-specific encounters, both ofwhich were characterized by low levels of aggression and amicability. Thus, due to the lack of aggression, direct competition appearsweak and instead mutual avoidance may reduce or minimize interspecific interactions, potentially promoting coexistence.

关键词： Avoidance Coexistence Elephantulus myurus Intraspecific behavior Interspecific behavior Micaelamys namaquensis

The evolving ENSO observing system

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National Science Review 2018年第6期5卷 805-807页

作者： Dake Chen neville Smith William Kessler State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of Oceanography

El Nio–Southern Oscillation (ENSO)is by far the most energetic and influential short-term climate variability on our planet, originating from an instability of the large-scale ocean-atmosphere interaction in the tr... 详细信息

关键词： The evolving ENSO observing system TAO

Comparisons of corrosion behaviour for X65 and low Cr steels in high pressure CO2-saturated brine

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Journal of Materials Science & Technology 2020年第6期41卷 21-32页

作者： Yong Hua Sikiru Mohammed Richard Barker Anne neville Institute of Functional Surfaces School of Mechanical Engineering University of Leeds Leeds LS2 9JT United Kingdom

Appropriate materials for injection pipelines and tubing for carbon dioxide geologic storage is fundamental to ensure asset integrity and save *** paper evaluates the corrosion behaviour of X65,1Cr,3Cr and 5Cr,which have the potential to be injection pipeline/tubing *** influence of steel Cr content on the general and localised corrosion behaviour was investigated at time periods from 6 to 192 h at 60℃and 100 *** evolution,morphology and chemistry of corrosion products on the surface of each material were evaluated using a combination of scanning electron microscopy,energy dispersive X-ray spectroscopy and X-ray diffraction and related to their overall corrosion *** indicate that prior to the formation of protective films on the steel surfaces,the resistance of the materials to corrosion increase with increasing Cr content(Corrosion resistance:X651Cr>3Cr>5Cr).In terms of the corrosion products on X65,both inner amorphous and outer crystalline corrosion layers consist of *** the Cr-containing steels,the outer layer also comprises FeCO3,but the inner layer is enriched with Cr,and is predominantly amorphous Cr(OH)*** extent of localised corrosion(determined using surface profilometry)is noticeably less for X65 compared to the Cr-containing *** paper raises questions about the benefits that low Cr steels offer towards extending component design life compared to carbon steel under the test conditions considered here.

关键词： Carbon dioxide Corrosion X65 Low-Cr steels Iron carbonate Chromium hydroxide

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准则、规划和保护：在莫高窟的保护合作

敦煌研究 2024年第4期 18-29页

作者：内维尔·阿根纽玛莎·迪马斯莎伦·莎莉文王平先盖蒂保护研究所澳大利亚遗产委员会敦煌研究院编辑部

在中国国家文物局的支持下，敦煌研究院和盖蒂保护研究所已经在莫高窟和其他历史文化遗址有效地协同合作了约35年。在这些年中，双方开展了很多项目和活动。所有活动的指导原则都是通过保护干预、规划和管理、培训、研究和制定广泛适用... 详细信息

在中国国家文物局的支持下，敦煌研究院和盖蒂保护研究所已经在莫高窟和其他历史文化遗址有效地协同合作了约35年。在这些年中，双方开展了很多项目和活动。所有活动的指导原则都是通过保护干预、规划和管理、培训、研究和制定广泛适用的方法来保护遗址的诸多价值。

关键词：莫高窟敦煌研究院盖蒂保护研究所文物保护合作

Exercise for stroke prevention

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Stroke & Vascular Neurology 2018年第2期3卷 59-68页

作者： Peter L Prior neville Suskin Lawson Health Research Institution LondonOntarioCanada St.Josephs Health Care Cardiac Rehabilitation and Secondary Prevention Program LondonOntarioCanada Department of Medicine(Cardiology) Schulich School of Medicine&DentistryWestern UniversityLondonOntarioCanada

We review evidence concerning exercise for stroke *** biological reasons suggest that exercise would be important in preventing *** definitive randomised controlled trials evaluating the impact of physical activity(PA)and exercise on preventing stroke and mortality are lacking,observational studies,small randomised controlled trials and meta-analyses have provided evidence that PA and exercise favourably modify stroke risk factors,including hypertension,dyslipidaemia,diabetes,sedentary lifestyle,obesity,excessive alcohol consumption and tobacco *** is,therefore,important to understand the factors associated with poststroke PA/exercise and cardiorespiratory *** associated factors include self-efficacy,social support and quality of patients’relationships with health *** associated factors include logistical barriers,medical comorbidities,stroke-related deficits,negative exercise beliefs,fear of falling,poststroke fatigue,arthropathy/pain and *** research is needed to specify efficacious behavioural approaches to increase poststroke *** techniques probably include physician endorsement of exercise programmesto patients,enhancement of patient-professional relationships,providing patients an exercise rationale,motivational interviewing,collaborative goal-setting with patients,addressing logistical concerns,social support in programsmes,structured exercise programming,individualised behavioural instruction,behavioural diary recording,reviewing behavioural consequences of exercise efforts,reinforcing successful exercise *** programming without counselling may increase short-term activity;simple advice or information-giving is probably *** patients or those with cognitive impairment may need increased structure,with emphasis on behaviour per se,versus self-regulation *** support the latest American Heart Association/American Stroke Associati

关键词： prevention behaviour programming

Constraining Design:Applying the Insights of Cognitive Work Analysis to the Design of Novel In-Car Interfaces to Support Eco-Driving

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Automotive Innovation 2020年第1期3卷 30-41页

作者： Craig K.Allison neville A.Stanton Solent University East Park TerraceSouthampton SO140YNUK Transportation Research Group University of SouthamptonBoldrewood Innovation CampusSouthampton SO167QFUK

The design with intent(DwI)toolkit assists designers in creating novel designs and ***,however,is not constrained to any degree,making it impossible to know whether the produced designs adequately account for users’*** contrast,cognitive work analysis(CWA)is a human factors research tool that seeks to map a system and account for users’needs,yet does not provide clear guidelines for progressing such analysis into workable designs with which users can *** paper seeks to present a proof-of-concept investigation to demonstrate that DwI can be suitably constrained and validated by insights gained from ***,in turn,benefits by having a suitable toolkit for progressing *** teams of individuals without design backgrounds were able to develop mock-up in-vehicle interfaces aimed at reducing fuel *** teams were able to use DwI toolkit to articulate the genesis of their ideas,which in turn could be directly linked to system needs identified within CWA.

关键词： Design with intent Cognitive work analysis Interface design Eco-driving