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Gastroesophageal signet ring cell carcinoma morbidity and mortality: A retrospective review

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1629-1636页

作者： Megan Grinlinton Chris Furkert Andrew Maurice neville Angelo Michael Booth Department of General Surgery North Shore HospitalAuckland 0620New Zealand Department of Pathology North Shore HospitalAuckland 0620New Zealand

BACKGROUND Upper gastrointestinal(GI)signet ring cell carcinomas(SRCC)confer a poor *** benefit of operative intervention for this patient group is contro-versial in terms of overall *** To investigate factors relating to survival in patients with upper GI *** A retrospective,tertiary,single-centre review of patients who were diagnosed with oesophageal,gastroesophageal junction and gastric SRCC was *** primary outcome was to compare mortality of patients who underwent operative management with those who had nonoperative ***-dary outcomes included assessing the relationship between demographic and histopathological factors,and *** One hundred and thirty-one patients were *** one-year survival for the operative group was 81%and for the nonoperative group was 19.1%.The five-year survival in the operative group was 28.6%vs 1.5%in the nonoperative *** difference in overall survival between groups was statistically significant(HR 0.19,95%CI(0.13-0.30),P<0.001).There was no difference in survival when ad-justing for age,smoking status or *** multivariate analysis,patients who underwent surgical management,those with a lower stage of disease,and those with a lower Charlson Comorbidity Index(CCI)had significantly improved *** Well-selected patients with upper GI SRCC appear to have reasonable medium-term survival following *** surgery to a carefully selected patient group may improve the outcome for this disease.

关键词： Signet ring cell carcinoma Gastric cancer Oesophageal cancer Poorly cohesive gastric cancer Diffuse gastric cancer

Mitochondrial therapeutics and mitochondrial transfer for neurodegenerative diseases and aging

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Neural Regeneration Research 2025年第3期20卷 794-796页

作者： neville Ng Michelle Newbery Nicole Miles Lezanne Ooi Molecular Horizons and School of Chemistry and Molecular Bioscience University of WollongongWollongongNSWAustralia

Mitochondrial dysfunction and neurodegeneration:Progressive neurodegenerative diseases affect a significant proportion of the population;in a single year,there are as many as 276 million disabilities and 9 million dea... 详细信息

关键词： degenerative diseases Mitochondrial

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VSAT用户网络实例

成都信息工程学院学报 1993年第2期15卷 78-88页

作者： K.M.Sundara Murthy Barry O'Neal Jay Alan Josepth J.Sanchez John Barry N.seshagiri Barry G.Evans Dennis Shanley neville miller Jim Stratigos Robert Mullinax John W.Warner Paul Noble 王春芳

本文简要介绍具有代表性的几种VSAT网。这些网络的选择是研究了世界各地正在运行的不同类型的VSAT网后作出的。选择样本时考虑了如下几种因素,以便读者能够获取有用的信息,并对当前VSAT的状况有一个真实的了解。这些因素包括网络种类(... 详细信息

本文简要介绍具有代表性的几种VSAT网。这些网络的选择是研究了世界各地正在运行的不同类型的VSAT网后作出的。选择样本时考虑了如下几种因素,以便读者能够获取有用的信息,并对当前VSAT的状况有一个真实的了解。这些因素包括网络种类(共享的还是专用的)、区域(全球范围)、技术应用、业务、销售、用户(按生意种类分)、网络状态等。

关键词： VSAT 用户网络卫星网数据传送用户服务话音业务 Chrysler 地面网络主机系统业务网

Amyloid pores in mitochondrial membranes

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Neural Regeneration Research 2021年第11期16卷 2225-2226页

作者： neville Vassallo Department of Physiology&Biochemistry Faculty of Medicine and SurgeryUniversity of MaltaMsida MSD 2080Malta

Neurodegenerative diseases of the amyloid type include common conditions such as Alzheimer’s disease,Parkinson’s disease,Huntington’s disease and amyotrophic lateral *** the fact that the phenotypes of these neuropathic maladies differ widely,ranging from cognitive to motor and psychotic disturbances,they are all characterized by the pathological accumulation and deposition in the central nervous system of well-ordered protein aggregates known as amyloid *** evidence indicates that rather than the end-stage mature fibrils,however,it is the smaller,metastable intermediate forms(known as oligomers)of the aggregated protein and peptides which represent the most neurotoxic species(Chiti and Dobson,2017).One suggested mechanism for such toxicity appears to involve the ability of oligomers to interact with plasma membranes whilst inducing cell leakage(Surguchov et al.,2017).However,contemporary work increasingly points to mitochondria,and hence mitochondrial membranes,as preferential targets for the pathogenic action of oligomers in the neuronal cell(Ghio et al.,2016).

关键词： Huntington membranes amyloid

Behavioral interactions between a coexisting rodent Micaelamys namaquensis and macroscelid Elephantulus myurus

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Current Zoology 2010年第4期56卷 395-400页

作者： Jennifer LANCASTER neville PILLAY School of Animal Plant and Environmental Sciences University of the Witwatersrand

A number of mechanisms are known to influence coexistence in small mammal communities. However, the role ofbehavioral interactions in promoting species coexistence is under-represented in the literature. We studied the behavioral interactionsof two coexisting small mammals, the Namaqua rock mouse Micaelamys namaquensis (Rodentia) and the Rock sengi Elephantulusmyurus (Macroscelidae), which have high dietary and microhabitat overlap. Using wild-caught individuals, intra- andinterspecific dyadic encounters were staged in tanks on a neutral rocky outcrop. Interspecific dyads displayed significantly moreactive avoidance behavior. There was no support for the prediction that the larger, more specialist species, E. myurus, is behaviorallydominant over M. namaquensis. Intraspecific encounters of E. myurus showed significantly more passive avoidance andamicable behavior, whereas the behavior of M. namaquensis did not differ between intra- and inter-specific encounters, both ofwhich were characterized by low levels of aggression and amicability. Thus, due to the lack of aggression, direct competition appearsweak and instead mutual avoidance may reduce or minimize interspecific interactions, potentially promoting coexistence.

关键词： Avoidance Coexistence Elephantulus myurus Intraspecific behavior Interspecific behavior Micaelamys namaquensis

The evolving ENSO observing system

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National Science Review 2018年第6期5卷 805-807页

作者： Dake Chen neville Smith William Kessler State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of Oceanography

El Nio–Southern Oscillation (ENSO)is by far the most energetic and influential short-term climate variability on our planet, originating from an instability of the large-scale ocean-atmosphere interaction in the tr... 详细信息

关键词： The evolving ENSO observing system TAO

Comparisons of corrosion behaviour for X65 and low Cr steels in high pressure CO2-saturated brine

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Journal of Materials Science & Technology 2020年第6期41卷 21-32页

作者： Yong Hua Sikiru Mohammed Richard Barker Anne neville Institute of Functional Surfaces School of Mechanical Engineering University of Leeds Leeds LS2 9JT United Kingdom

Appropriate materials for injection pipelines and tubing for carbon dioxide geologic storage is fundamental to ensure asset integrity and save *** paper evaluates the corrosion behaviour of X65,1Cr,3Cr and 5Cr,which have the potential to be injection pipeline/tubing *** influence of steel Cr content on the general and localised corrosion behaviour was investigated at time periods from 6 to 192 h at 60℃and 100 *** evolution,morphology and chemistry of corrosion products on the surface of each material were evaluated using a combination of scanning electron microscopy,energy dispersive X-ray spectroscopy and X-ray diffraction and related to their overall corrosion *** indicate that prior to the formation of protective films on the steel surfaces,the resistance of the materials to corrosion increase with increasing Cr content(Corrosion resistance:X651Cr>3Cr>5Cr).In terms of the corrosion products on X65,both inner amorphous and outer crystalline corrosion layers consist of *** the Cr-containing steels,the outer layer also comprises FeCO3,but the inner layer is enriched with Cr,and is predominantly amorphous Cr(OH)*** extent of localised corrosion(determined using surface profilometry)is noticeably less for X65 compared to the Cr-containing *** paper raises questions about the benefits that low Cr steels offer towards extending component design life compared to carbon steel under the test conditions considered here.

关键词： Carbon dioxide Corrosion X65 Low-Cr steels Iron carbonate Chromium hydroxide

Exercise for stroke prevention

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Stroke & Vascular Neurology 2018年第2期3卷 59-68页

作者： Peter L Prior neville Suskin Lawson Health Research Institution LondonOntarioCanada St.Josephs Health Care Cardiac Rehabilitation and Secondary Prevention Program LondonOntarioCanada Department of Medicine(Cardiology) Schulich School of Medicine&DentistryWestern UniversityLondonOntarioCanada

We review evidence concerning exercise for stroke *** biological reasons suggest that exercise would be important in preventing *** definitive randomised controlled trials evaluating the impact of physical activity(PA)and exercise on preventing stroke and mortality are lacking,observational studies,small randomised controlled trials and meta-analyses have provided evidence that PA and exercise favourably modify stroke risk factors,including hypertension,dyslipidaemia,diabetes,sedentary lifestyle,obesity,excessive alcohol consumption and tobacco *** is,therefore,important to understand the factors associated with poststroke PA/exercise and cardiorespiratory *** associated factors include self-efficacy,social support and quality of patients’relationships with health *** associated factors include logistical barriers,medical comorbidities,stroke-related deficits,negative exercise beliefs,fear of falling,poststroke fatigue,arthropathy/pain and *** research is needed to specify efficacious behavioural approaches to increase poststroke *** techniques probably include physician endorsement of exercise programmesto patients,enhancement of patient-professional relationships,providing patients an exercise rationale,motivational interviewing,collaborative goal-setting with patients,addressing logistical concerns,social support in programsmes,structured exercise programming,individualised behavioural instruction,behavioural diary recording,reviewing behavioural consequences of exercise efforts,reinforcing successful exercise *** programming without counselling may increase short-term activity;simple advice or information-giving is probably *** patients or those with cognitive impairment may need increased structure,with emphasis on behaviour per se,versus self-regulation *** support the latest American Heart Association/American Stroke Associati

关键词： prevention behaviour programming

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准则、规划和保护:在莫高窟的保护合作

敦煌研究 2024年第4期 18-29页

作者：内维尔·阿根纽玛莎·迪马斯莎伦·莎莉文王平先(译) 盖蒂保护研究所美国洛杉矶90001 澳大利亚遗产委员会澳大利亚堪培拉0200 敦煌研究院编辑部甘肃兰州730030

在中国国家文物局的支持下,敦煌研究院和盖蒂保护研究所已经在莫高窟和其他历史文化遗址有效地协同合作了约35年。在这些年中,双方开展了很多项目和活动。所有活动的指导原则都是通过保护干预、规划和管理、培训、研究和制定广泛适用的... 详细信息

在中国国家文物局的支持下,敦煌研究院和盖蒂保护研究所已经在莫高窟和其他历史文化遗址有效地协同合作了约35年。在这些年中,双方开展了很多项目和活动。所有活动的指导原则都是通过保护干预、规划和管理、培训、研究和制定广泛适用的方法来保护遗址的诸多价值。

关键词：莫高窟敦煌研究院盖蒂保护研究所文物保护合作