检索结果-南通市图书馆

Brain metabolic profile assessed by magnetic resonance spectroscopy in children with Down syndrome:Relation to intelligence quotient

引用

World Journal of Clinical Pediatrics 2023年第5期12卷 310-318页

作者： nesreen safwat el feil Heba S elmahdy Rasha Ahmed elmahdy Ahmed Abd-elbasset Aboelezz Heba S Dawoud Mohammed Al-Beltagi Department of Pediatrics Faculty of MedicineTanta UniversityTanta 31527Al GharbiaEgypt Department of Radiology University Medical CenterDr.Sulaiman Al-Habib Medical GroupManama 26671ManamaBahrain Department of Pediatrics University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain Department of Pediatrics University Medical CenterDr.Sulaiman Al-Habib Medical GroupManama 26671ManamaBahrain

BACKGROUND Down syndrome(DS)is one of the most common causes of intellectual *** with DS have varying intelligence quotient(IQ)that can predict their learning *** To assess the brain metabolic profiles of children with DS and compare them to standard controls,using magnetic resonance spectroscopy(MRS)and correlating the results with *** This case-control study included 40 children with DS aged 6-15 years and 40 age and sex-matched healthy children as *** was used to evaluate ratios of choline/creatine(Cho/Cr),N-acetyl aspartic acid/creatine(NAA/Cr),and myoinositol/creatine(MI/Cr(in the frontal,temporal,and occipital lobes and basal ganglia and compared to controls and correlated with *** Children with DS showed significant reductions in NAA/Cr and MI/Cr and a non-significant reduction in Cho/Cr in frontal lobes compared to ***,we observed significant decreases in NAA/Cr,MI/Cr,and Cho/Cr in the temporal and occipital lobes and basal ganglia in children with DS compared to ***,there was a significant correlation between IQ and metabolic ratios in the brains of children with *** Brain metabolic profile could be a good predictor of IQ in children with DS.

关键词： Children Down syndrome Magnetic resonance spectroscopy Metabolic profile Intelligence quotient

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：