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Bio-Inspired Numerical Analysis of COVID-19 with Fuzzy Parameters

Computers, Materials & Continua 2022年第8期72卷 3213-3229页

作者： F.M.Allehiany Fazal Dayan F.F.Al-Harbi nesreen althobaiti Nauman Ahmed Muhammad Rafiq Ali Raza Mawahib Elamin Department of Mathematical Sciences College of Applied SciencesUmm Al-Qura UniversityMakkah21955Saudi Arabia Department of Mathematics and Statistics University of LahoreLahorePakistan Department of Mathematics School of ScienceUniversity of Management and TechnologyLahorePakistan Department of Physics College of SciencePrincess Nourah Bint Abdulrahman UniversityRiyadh11671Saudi Arabia Department of Mathematics and Statistics College of ScienceTaif UniversityTaif21944Saudi Arabia Department of Mathematics Faculty of SciencesUniversity of Central PunjabLahorePakistan Department of Mathematics Govt.Maulana Zafar Ali Khan Graduate College WazirabadPunjab Higher Education Department(PHED)Lahore54000Pakistan Department of Mathematics College of Science and ArtsQassim UniversityRiyadh Al KhabraSaudi Arabia

Fuzziness or uncertainties arise due to insufficient knowledge,experimental errors,operating conditions and parameters that provide inaccurate *** concepts of susceptible,infectious and recovered are uncertain due to the different degrees in susceptibility,infectivity and recovery among the individuals of the *** differences can arise,when the population groups under the consideration having distinct habits,customs and different age groups have different degrees of resistance,*** realistic models are needed which consider these different degrees of susceptibility infectivity and recovery of the *** this paper,a Susceptible,Infected and Recovered(SIR)epidemic model with fuzzy parameters is *** infection,recovery and death rates due to the disease are considered as fuzzy *** basic reproduction number and fuzzy equilibrium points have been derived for the studied *** is then solved numerically with three different techniques,forward Euler,Runge-Kutta fourth order method(RK-4)and the nonstandard finite difference(NSFD)methods *** NSFD technique becomes more efficient and reliable among the others and preserves all the essential features of a continuous dynamical system.

关键词： Fuzzy parameters SIR model NSFD scheme fuzzy equilibrium points fuzzy stability analysis

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New Trends in the Modeling of Diseases Through Computational Techniques

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Computer Systems Science & Engineering 2023年第6期45卷 2935-2951页

作者： nesreen althobaiti Ali Raza Arooj Nasir Jan Awrejcewicz Muhammad Rafiq Nauman Ahmed Witold Pawłowski Muhammad Jawaz Emad E.Mahmoud Department of Mathematics and Statistics College of ScienceTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Department of Mathematics Govt.Maulana Zafar Ali Khan Graduate College WazirabadPunjab Higher Education Department(PHED)Lahore54000Pakistan Baqai Medical University Karachi75340Pakistan Shalamar Medical and Dental College Lahore54000Pakistan Department of Automation Biomechanics and MechatronicsLodz University of Technology1/15 Stefanowskiego St.90-924LodzPoland Department of Mathematics Faculty of Sciences and TechnologyUniversity of Central PunjabLahore54000Pakistan Department of Mathematics and Statistics University of LahoreLahore54590Pakistan Institute of Machine Tools and Production Engineering Lodz University of Technology1/15 Stefanowskiego St.90-537LodzPoland

The computational techniques are a set of novel problem-solving methodologies that have attracted wider attention for their excellent *** handling strategies of real-world problems are artificial neural networks(ANN),evolutionary computing(EC),and many *** estimated fifty thousand to ninety thousand new leishmaniasis cases occur annually,with only 25%to 45%reported to the World Health Organization(WHO).It remains one of the top parasitic diseases with outbreak and mortality *** 2020,more than ninety percent of new cases reported to World Health Organization(WHO)occurred in ten countries:Brazil,China,Ethiopia,Eritrea,India,Kenya,Somalia,South Sudan,Sudan,and *** transmission of visceral leishmaniasis is studied dynamically and *** study included positivity,boundedness,equilibria,reproduction number,and local stability of the model in the dynamical *** detailed methods like Runge Kutta and Euler depend on time steps and violate the physical relevance of the *** produce negative and unbounded results,so in disease dynamics,such developments have no biological significance;in other words,these results are *** the implicit nonstandard finite difference method does not depend on time step,positive,bounded,dynamic and *** the computational techniques and their results were compared using computer simulations.

关键词： Real-world problem differential equations computational techniques analysis

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Model-based adaptive controller for personalized ventilation and thermal comfort in naturally ventilated spaces

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Building Simulation 2021年第6期14卷 1757-1771页

作者： Dalia Ghaddar Mariam Itani nesreen Ghaddar Kamel Ghali Joseph Zeaiter Mechanical Engineering Department American University of BeirutP.O.Box 11-0236Beirut 1107-2020Lebanon Mechanical Engineering Department Phoenicia UniversityDistrict of ZahraniLebanon Bahaa and Walid Bassotne Department of Chemical Engineering and Advanced Energy American University of BeirutBeirutLebanon

This work develops a standalone autonomously controlled personalized ventilation(PV)unit in a naturally ventilated(NV)office space to maintain acceptable thermal comfort{TQ under steady and transient indoor conditions and activity *** NV-PV proportional integral derivative(PID)controller adjusts the PV supply temperature(7spv)at the occupant set flow rate(Qspv)based on predicted TC using a regression *** target TC level that the controller attains at all times is between 0(neutral)and 1(slightly comfortable).Process transfer functions were developed and then used to find the adaptive PID tuning coefficients using the Internal Model Control(IMC)*** controller was tested in a case study at indoor temperature range of 25 to 33℃ with relative humidity range of 55%and 80%.It was shown that the NV-PV controller adjusted Tspv to maintain acceptable TC under transients of indoor conditions and metabolic rates.

关键词： adaptive PID controller personalized ventilation natural ventilation thermal comfort

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Psychological interventions for adherence, metabolic control, and coping with stress in adolescents with type 1 diabetes:a systematic review

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World Journal of Pediatrics 2020年第5期16卷 456-470页

作者： Yousef M.Aljawarneh nesreen M.Al-Qaissi Hana Y.Ghunaim Health Sciences Division School of NursingHigher Colleges of TechnologyP.O.Box 1626FujairahUnited Arab Emirates Higher Colleges of Technology P.O.Box 1626FujairahUnited Arab Emirates Fatima College of Health Sciences Institute of Applied TechnologyP.O.Box 24162Al AinUnited Arab Emirates

Background The aim of this review was to summarize and identify the variations in the effectiveness of psychological interventions on adherence,metabolic control,and coping with stress in adolescents with type 1 diabetes(T1D).Methods An electronic search of literature was performed using PubMed(NLM),Embase(Ovid),CINAHL Plus(EBSCO-host),PsycINFO(Ovid),and Google *** search was limited to include articles reported the effect of one of the psychological interventions:cognitive behavioral therapy(CBT),coping skills training(CST),stress management,or psychotherapy *** report included peer-reviewed articles published in English from January 1990 until May 2019in adolescents with T1D,and summarizes the results of 24 studies that met the inclusion *** Psychological interventions showed differential effects on adherence,metabolic control,and coping with stress in adolescents with *** interventions using principles of CBT appear to have a superior positive effect on regimen adherence compared with other types of psychological *** contrast,metabolic control was significantly improved with the implementation of CST and some forms of *** management and psychotherapy interventions showed significant promises for adolescents to cope with their diabetes-related daily *** However,the findings may add some promises to diabetes management in adolescents,additional research to understand the effect of these interventions is needed.

关键词： Adherence Adolescents Coping Metabolic control Type 1 diabetes

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Investigating the influence of gamma ray energies and steel fiber on attenuation properties of reactive powder concrete

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Nuclear Science and Techniques 2017年第10期28卷 113-120页

作者： Shatha D.Mohammed Wasan Z.Majeed nesreen B.Naji Nada Mahdi Fawzi Department of Civil College of EngineeringUniversity of BaghdadBaghdadIraq Department of Physics College of ScienceUniversity of BaghdadBaghdadIraq

The effect of gamma ray energies and volume ratio of micro steel fiber(1 and 1.5%) on attenuation properties of reactive powder concrete(70 MPa compressive strength) was investigated. Different characteristics have been considered such as linear attenuation coefficient,mass attenuation coefficient, and half-value *** iodide crystal with a gamma ray spectrometer and collimated beam of gamma ray has been implemented to perform the experimental test. Three sources(Cs-137, Co-60, and Bi-207) with energies of(0.662, 1.17 1.33, 0.569,and 1.063) MeV were adopted in the test. The results obtained indicated that mass attenuation coefficient is proportioned inversely with gamma ray energies and directly with a volume ratio of micro steel fiber. The linear attenuation coefficient and half-value thickness of the tested samples have been calculated and discussed. The obtained results showed that increasing the volume ratio of steel fiber has modified the adequacy of the reactive powder concrete as a shielding element since it increases the density and reduces the half-value thickness.

关键词：活性粉末混凝土衰减特性射线能量钢纤维性能影响线性衰减系数质量衰减系数纤维体积比

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Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats:Molecular study

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World Journal of Hepatology 2021年第3期13卷 328-342页

作者： Amany Helmy Hasanin Eman K Habib nesreen El Gayar Marwa Matboli Clinical Pharmacology Department Faculty of MedicineAin Shams UniversityCairo 11318Egypt Anatomy and Embryology Department Faculty of MedicineAin Shams UniversityCairo 11318Egypt Medical Biochemistry and Molecular Biology Department Faculty of MedicineAin Shams UniversityCairo 11381Egypt

BACKGROUND Diethylnitrosamine(DEN)induces hepatic neoplastic lesions over a prolonged *** To investigate the promotive action of 2-acetylaminofluorene(2-AAF)when combined with DEN in order to develop a rat model for induction of precancerous lesion and investigate the molecular mechanism underlying the activity of *** The pre-precancerous lesions were initiated by intraperitoneal injection of DEN for three weeks consecutively,followed by one intraperitoneal injection of 2-AAF at three different doses(100,200 and 300 mg/kg).Rats were separated into naïve,DEN,DEN+100 mg 2-AAF,DEN+200 mg 2-AAF,and DEN+300 mg 2-AAF *** were sacrificed after 10 wk and 16 *** functions,level of alpha-fetoprotein,glutathione S-transferase-P and proliferating cell nuclear antigen staining of liver tissues were *** mRNA level of RAB11A,BAX,p53,and Cyclin E and epigenetic regulation by long-noncoding RNA(lncRNA)RP11-513I15.6,miR-1262(microRNA),and miR-1298 were assessed in the sera and liver tissues of the *** 2-AAF administration significantly increased the percent area of the precancerous foci and cell proliferation along with a significant decrease in RAB11A,BAX,and p53 mRNA,and the increase in Cyclin E mRNA was associated with a marked decrease in lncRNA RP11-513I15.6 expression with a significant increase in both miR-1262 and *** 2-AFF promoted hepatic precancerous lesions initiated through DEN by decreasing autophagy,apoptosis,and tumor suppression genes,along with increased cell proliferation,in a time-and dose-dependent *** actions were mediated under the epigenetic regulation of lncRNA RP11-513I15.6/miR-1262/miR-1298.

关键词： Acetylaminofluorene Hepatic precancerous lesion Diethylnitrosamine Autophagy Apoptosis MicroRNA

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Mesenchymal stem cells and COVID-19: What they do and what they can do

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World Journal of Stem Cells 2021年第9期13卷 1318-1337页

作者： Ejlal Abu-El-Rub Ramada R Khasawneh Fatimah Almahasneh Zaid Altaany nesreen Bataineh Hana Zegallai Saravanan Sekaran Department of Physiology and Pathophysiology University of ManitobaWinnipeg R2H2A6Canada Department of Physiology and Pathophysiology Basic Medical SciencesYarmouk UniversityIRBID 21163Jordan Department of Anatomy and Histology Basic Medical SciencesYarmouk UniversityIRBID 21163Jordan Department of Physiology and Pharmacology Basic Medical SciencesYarmouk UniversityIRBID 21163Jordan Department of Biochemistry and Genetics Basic Medical SciencesYarmouk UniversityIRBID 21163Jordan Department of Pathology Basic Medical SciencesYarmouk UniversityIRBID 21163Jordan Department of Pharmacology and Therapeutics University of ManitobaWinnipeg R2H2A6Canada Department of Pharmacology Saveetha Dental College and Hospitals to be UniversityChennai 600077India

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) orcoronavirus disease 2019 (COVID-19) pandemic has exhausted the health systemsin many countries with thousands cases diagnosed daily. The currently usedtreatment guideline is to manage the common symptoms like fever and cough,but doesn’t target the virus itself or halts serious complications arising from thisviral infection. Currently, SARS-CoV-2 exhibits many genetic modulations whichhave been associated with the appearance of highly contagious strains. Thenumber of critical cases of COVID-19 increases markedly, and many of theinfected people die as a result of respiratory failure and multiple organ dysfunction. The regenerative potential of mesenchymal stem cells (MSCs) has beenextensively studied and confirmed. The impressive immunomodulation and antiinflammatoryactivity of MSCs have been recognized as a golden opportunity forthe treatment of COVID-19 and its associated complications. Moreover, MSCsregenerative and repairing abilities have been corroborated by many studies withpositive outcomes and high recovery rates. Based on that, MSCs infusion could bean effective mechanism in managing and stemming the serious complications andmultiple organ failure associated with COVID-19. In the present review, wediscuss the commonly reported complications of COVID-19 viral infection and theestablished and anticipated role of MSCs in managing these complications.

关键词： SARS-CoV-2 COVID-19 Mesenchymal stem cells Inflammation Acute respiratory distress syndrome Pulmonary fibrosis Pneumonia Renal injury Cardiovascular diseases Regeneration Anti-inflammatory

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Instrumented assisted soft tissue mobilization vs extracorporeal shock wave therapy in treatment of myofascial pain syndrome

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World Journal of Orthopedics 2023年第7期14卷 572-581页

作者： Nourhan Elsayed Shamseldeen Mohammed Moustafa Aldosouki Hegazy Nadia Abdalazeem Fayaz nesreen Fawzy Mahmoud Department of Physical Therapy for Musculoskeletal Disorders&Its Surgery Faculty of Physical TherapyCairo UniversityCairo 14531Egypt

BACKGROUND Active myofascial trigger points(TrPs)often occur in the upper region of the upper trapezius(UT)*** TrPs can be a significant source of neck,shoulder,and upper back pain and *** TrPs and their related pain and disability can adversely affect an individual’s everyday routine functioning,work-related productivity,and general quality of *** To investigate the effects of instrument assisted soft tissue mobilization(IASTM)vs extracorporeal shock wave therapy(ESWT)on the TrPs of the UT *** A randomized,single-blind,comparative clinical study was conducted at the Medical Center of the Egyptian Railway Station in *** patients(28 females and 12 males),aged between 20-years-old and 40-years-old,with active myofascial TrPs in the UT muscle were randomly assigned to two equal groups(A and B).Group A received IASTM,while group B received *** group was treated twice weekly for 2 *** groups received muscle energy technique for the UT *** were evaluated twice(pre-and posttreatment)for pain intensity using the visual analogue scale and for pain pressure threshold(PPT)using a pressure *** Comparing the pre-and post-treatment mean values for all variables for group A,there were significant differences in pain intensity for TrP1 and TrP2(P=0.0001)and PPT for TrP1(P=0.0002)and TrP2(P=0.0001).Also,for group B,there were significant differences between the pre-and post-treatment pain intensity for TrP1 and TrP2 and PPT for TrP1 and TrP2(P=0.0001).There were no significant differences between the two groups in the post-treatment mean values of pain intensity for TrP1(P=0.9)and TrP2(P=0.76)and PPT for TrP1(P=0.09)and for TrP2(P=0.91).CONCLUSION IASTM and ESWT are effective methods for improving pain and PPT in patients with UT muscle *** is no significant difference between either treatment method.

关键词： Myofascial trigger points Upper trapezius muscle Instrument-assisted soft tissue mobilization Extracorporeal shock wave therapy Myofascial pain syndrome

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Fallopian tube:Its role in infertility and gynecological oncology

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World Journal of Obstetrics and Gynecology 2014年第2期3卷 35-41页

作者： nesreen Magdy Mona El-Bahrawy Department of Pathology National Cancer Institute Cairo University Cairo 14211 Egypt Department of Histopathology Imperial College London Hammersmith Hospital London W12 0NN United Kingdom Department of Pathology Faculty of Medicine University of Alexandria Azarita 31211 Egypt

Disorders of the fallopian tube play a very important role in both infertility and gynaecological oncology. Tubal factor infertility is considered among the leading causes of female factor infertility. Many tubal disorders are related to infertility including congenital anomalies, acute and chronic inflammatory diseases, endometriosis and other pathologies that result in partial or total fallopian tube obstruction. In the field of gynaecological oncology, ovarian surface epithelial tumors remain one of the most fatal malignancies in women worldwide carrying the worst prognosis among female genital malignancies. For decades, the cell of origin of epithelial tumors has remained controversial and was largely believed to be surface ovarian epithelium. Recently several studies suggested that there is a major role of the fallopian tube in the development of ovarian surface epithelial tumors, mainly high grade serous carcinoma and other tumour types. In this article we review the role of the fallopian tube in both infertility and gynaecological oncology.

关键词： Fallopian tube Infertility Endometriosis Salpingitis Serous carcinoma

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Optimized Operation of a Solar-Driven Thermoelectric Dehumidification System for Fresh Water Production

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Journal of Energy and Power Engineering 2012年第6期6卷 878-891页

作者： Muhyiddine Jradi nesreen Ghaddar Kamel Ghali Department of Mechanical Engineering American University of Beirut Beirut 1107-2020 Lebanon

The work presents a parametric analysis of the performance of a solar-driven thermoelectric system to dehumidify air and produce fresh water. The system is combined with a solar distiller humidifying ambient air to enhance distillate output to meet the specified fresh water needs for a residential application. The presented system is a totally renewable energy-based system taking advantage of the clean solar energy. A model is developed to simulate the air dehumidification process using TEC （thermoelectrically cooled） channels. An optimization problem for setting system operational parameters is formulated to meet the fresh water requirement of 10 liters per day for a typical residential application in the Lebanese coastal humid climate. Using five TEC channels of length of 1.2 m and area of 0.07 - 0.05 m^2 integrated with 1.2 m^2 solar distiller is capable of meeting the water demand, where the air mass flow rate introduced to each TEC channel is optimally set at 0.0155 kg/s. The optimal electrical current input to the TEC modules from the photovoltaic solar panels varied depending on the month and is set at 2.2 A in June, 2.1 A in July and 2.0 A in August, September and October per each TEC module.

关键词： Thermoelectric cooling humidification/dehumidification process solar energy water production design and optimization.

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