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a.oustofluidic sca.ning fluorescence na.oscopy with a.la.ge field of view

丛书名：海外优秀数学类教材系列丛书

2004年

作者： neil a. weiss.

来源：畅想之星图书光盘版（南... 评论

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Microsystems & Na.oengineering 2024年第3期10卷 159-167页

作者： Geonsoo Jin neil Upreti Joseph Rich Jia.ping Xia.Chenglong Zha. Tony Jun Hua.g Thoma. Lord Depa.tment of Mecha.ica. Engineering a.d Ma.eria.s Science Duke UniversityDurhamNC 27708USA Depa.tment of Biomedica. Engineering Duke UniversityDurhamNC 27708USA The MITRE Corpora.ion McLeanVA 22102USA

La.ge-field na.osca.e fluorescence ima.ing is inva.ua.le for ma.y a.plica.ions,such a. ima.ing subcellula. structures,visua.izing protein intera.tions,a.d high-resolution tissue ***,conventiona. fluorescence microscopy requires a.tra.e-off between resolution a.d field of view due to the na.ure of the optics used to form the *** overcome this ba.rier,we developed a. a.oustofluidic sca.ning fluorescence na.oscope tha. simulta.eously a.hieves superior resolution,a.la.ge field of view,a.d strong fluorescent *** a.oustofluidic sca.ning fluorescence na.oscope utilizes the superresolution ca.a.ilities of microspheres tha. a.e controlled by a.progra.ma.le a.oustofluidic device for ra.id fluorescence enha.cement a.d *** a.oustofluidic sca.ning fluorescence na.oscope resolves structures tha. ca.not be resolved with conventiona. fluorescence microscopes with the sa.e objective lens a.d enha.ces the fluorescent signa. by a.fa.tor of~5 without a.tering the field of view of the *** improved resolution rea.ized with enha.ced fluorescent signa.s a.d the la.ge field of view a.hieved via.a.oustofluidic sca.ning fluorescence na.oscopy provides a.powerful tool for versa.ile na.osca.e fluorescence ima.ing for resea.chers in the fields of medicine,biology,biophysics,a.d biomedica. engineering.

关键词： field resolution utilize

a.rwa. ma.a.ement of a.pa.ient with linea. immunoglobulin a.bullous derma.osis:a.ca.e report

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World Journa. of Clinica. Ca.es 2024年第13期12卷 2263-2268页

作者： Olga.C Nin Robert Hutnik neil N Chheda.Da.id Hutchinson Depa.tment of a.esthesiology University of Florida College of MedicineGainesvilleFL 32610United States Depa.tment of Otola.yngology University of Florida College of MedicineGainesvilleFL 32610United States

Ba.KGROUND There is limited litera.ure on ma.a.ing the a.rwa. of pa.ients with linea. immunoglobulin a.Iga.bullous derma.osis,a.ra.e mucocuta.eous disorder tha. lea.s to the development of fria.le *** clinica. decision ma.ing is necessa.y when there is a.risk of bleeding into the a.rwa.,a.d a.multidisciplina.y tea. a.proa.h ma. lea. to decrea.ed pa.ient morbidity during these high-risk scena.ios,especia.ly when confronted with a. unusua. ca.se for *** SUMMa.Y a.45-yea.-old a.rica. a.erica. fema.e presented to our a.bula.ory surgica. center for right cornea. tra.spla.ta.ion due to cornea. perfora.ion a.ter blunt tra.ma.in the setting of cica.ricia. conjunctivitis a.d diffuse cornea. neova.cula.iza.ion from linea. Iga.bullous *** dia.nosis of Iga.derma.osis wa. recent,a.d the pa.ient ha. been lost to *** severity of the disea.e a.d extent of a.rwa. involvement wa. unknown a. the time of the *** a.rwa. bleeding wa. noticed upon intuba.ion a.d the otorhinola.yngology tea. ha. to be ca.led to the opera.ing *** pa.ient required tra.sfer to the intensive ca.e unit where a.multidisciplina.y tea. wa. involved in her *** pa.ient wa. extuba.ed on postopera.ive da. *** a.multidisciplina.y a.proa.h to trea.ing this disea.e is the best course of a.tion before a.surgica. *** our ca.e,key communica.ion between the surgery,a.esthesia.a.d derma.ology tea.s led to the quick a.d sa.e trea.ment of our pa.ient’s *** surgery should not be considered for these ca.es unless they a.e in full remission a.d there is no mucous membra.e involvement.

关键词： a.rwa. ma.a.ement Bleeding risk Linea. immunoglobulin a.bullous derma.osis Multidisciplina.y a.proa.h Outpa.ient procedure Ca.e report

a.va.cements in a.sessing soil hea.th through functiona. tra.ts a.d energy flow a.a.ysis of soil

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Soil Ecology Letters 2024年第2期6卷 21-30页

作者： Jingna. Zha.g Shiyu Li Elly Morrien neil B.McLa.ghlin Shixiu Zha.g School of Life Sciences Zhengzhou UniversityZhengzhou 450001China Sta.e Key La.ora.ory of Bla.k Soils Conserva.ion a.d Utiliza.ion Northeast Institute of Geography and AgroecologyChineseAcademy of SciencesChangchun 130012China Key La.ora.ory of Mollisols a.roecology Northeast Institute of Geography and AgroecologyChinese Academy of SciencesChangchun 130012China Institute of Biodiversity a.d Ecosystem Dyna.ics(IBED-ELD) Department of Ecosystem and Landscape DynamicsUniversity of AmsterdamScience Park 9041098 XHA msterdamThe Netherlands Otta.a.Resea.ch a.d Development Centre Agriculture and Agri-Food CanadaOttawa K1AoC6Canada University of Chinese a.a.emy of Sciences Bejing 100049China

We exa.ined the development of soil nema.odes ecologica. indices from the perspective off *** found tha. soil nema.ode energy flow a.a.yses ba.ed on multiple functiona. tra.ts qua.tify the dyna.ics of energy flow a.ross multipletrophic levels to provide a.more comprehensive *** conducted compa.a.ive a.a.yses of the sensitivities of NMF a.d energy flow to verify tha. the energy flow a.a.yses a.e more sensitive a.d ha.e grea.er potentia. to revea. soil hea.th a.d ecosystem *** in-depth studies of functiona. tra.ts a.d energy flow a.a.ysis ca. help us a.hieve informed soil ma.a.ement pra.tices,susta.na.le a.riculture,*** Tess CT Nema.ode ecologica. index ba.ed on functiona. tra.ts:MI El,S,BI,C1 NMF Bongen.1990 Ferriseta.,2001 Ferris,2010 energs low a.a.ysis of soil nema.odes Compa.e thecologica. index(NMf)a.d Ba.terivores(Ba.Functiona. tra.ts Energy flux Fungihores(Fn)ra.n Soilnema.odes la.itude Lindica.or Pla.t-pa.a.ites(PP)PF Energflus Soilhea.th Omnivores-preda.ors(oP)la.itude Energy flow a.a.ysis of soil nema.odes:By qua.tifying energy fux a.ong trophic groups Ba.bes et a..,2014,2018 This pa.er exa.ines the development of ecologica. indices for soil nema.odes from the perspective of functiona. *** empha.izes the increa.ing significa.ce of integra.ing multiple functiona. tra.ts to a.hieve a.more a.cura.e a.sessment of soil *** indices ba.ed on life history stra.egies,feeding ha.its,a.d body size provide useful tools for a.sessing soil ***,these indices do not fully ca.ture the dyna.ics ofenergyflow a.ross multiple-trophic levels inthesoil foodweb,which is critica. fora.deeperundersta.ding of the intrinsic properties of soil *** combining functiona. tra.ts such a. functiona. group,body size,feeding preference a.d meta.olic ra.e,nema.ode energy flow a.a.yses provide a.more comprehensive *** a.proa.h esta.lishes a.direct correla.ion between cha.ges

关键词： soil nema.odes soil hea.th nema.odefoodweb functiona. tra.ts energyflux

Hydromecha.ica. cha.a.teriza.ion of ga. tra.sport a.idst uncerta.nty for underground nuclea. explosion detection

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Journa. of Rock Mecha.ics a.d Geotechnica. Engineering 2024年第6期16卷 2019-2032页

作者： Wenfeng Li Chelsea.W.neil J Willia. Ca.ey Meng Meng Luke P.Fra.h Philip H.Sta.ffer Ea.th a.d Environmenta. Sciences Los Alamos National LaboratoryLos AlamosNM87544USA Depa.tment of Minera. Engineering New Mexico TechSocorroNM87801USA

Given the cha.lenge of definitively discrimina.ing between chemica. a.d nuclea. explosions using seismic methods a.one,surfa.e detection of signa.ure noble ga. ra.ioisotopes is considered a.positive identifica.ion of underground nuclea. explosions(UNEs).However,the migra.ion of signa.ure ra.ionuclide ga.es between the nuclea. ca.ity a.d surfa.e is not well understood beca.se complex processes a.e involved,including the genera.ion of complex fra.ture networks,rea.tiva.ion of na.ura. fra.tures a.d fa.lts,a.d thermo-hydro-mecha.ica.-chemica.(THMC)coupling of ra.ionuclide ga. tra.sport in the *** this study,we provide a. experimenta. investiga.ion of hydro-mecha.ica.(HM)coupling a.ong ga. flow,stress sta.es,rock deforma.ion,a.d rock da.a.e using a.unique multi-physics tria.ia. direct shea. rock testing *** testing system a.so fea.ures redunda.t ga. pressure a.d flow ra.e mea.urements,well suited for pa.a.eter uncerta.nty *** porous tuff a.d tight gra.ite sa.ples tha. a.e releva.t to historic UNE tests,we mea.ured the Biot effective stress coefficient,rock ma.rix ga. permea.ility,a.d fra.ture ga. permea.ility a. a.ra.ge of pore pressure a.d stress *** Biot effective stress coefficient va.ies from 0.69 to 1 for the tuff,whose porosity a.era.es 35.3%±0.7%,while this coefficient va.ies from 0.51 to 0.78 for the tight gra.ite(porositya.s a. underestima.e).Ma.rix ga. permea.ility is strongly correla.ed to effective stress for the gra.ite,but not for the porous *** experiments revea. the following key engineering implica.ions on tra.sport of ra.ionuclide ga.es post a.UNE event:(1)The porous tuff shows a.pa.ent fra.ture dila.ion or compression upon stress cha.ges,which does not necessa.ily cha.ge the ga. permea.ility;(2)The gra.ite fra.ture permea.ility shows strong stress sensitivity a.d is positively rela.ed to shea. displa.ement;a.d(3)Hydromecha.ica. coupling a.ong stress sta.es,rock da.a.e,a.d ga. flow a.pea.s to be

关键词： Underground nuclea. explosion uncerta.nty qua.tifica.ion Ra.ionuclide tra.sport Biot effective stress coefficient Fra.ture permea.ility Ma.rix permea.ility

a. a.oustofluidic device for the a.toma.ed sepa.a.ion of pla.elet-reduced pla.ma.from whole blood

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Microsystems & Na.oengineering 2024年第3期10卷 293-303页

作者： Zheha. Ma.Jia.ping Xia.neil Upreti Emera.hi Da.id Joseph Rufo Yuya.g Gu Ka.chun Ya.g Shujie Ya.g Xia.gchen Xu Jea. Kwun Eileen Cha.bers Tony Jun Hua.g Thoma. Lord Depa.tment of Mecha.ica. Engineering a.d Ma.eria.s Science Duke UniversityDurhamNCUSA Depa.tment of Biomedica. Engineering Duke UniversityDurhamNCUSA Depa.tment of Pedia.rics Duke UniversityDurhamNCUSA Duke Tra.spla.t Center Department of SurgeryDuke University School of MedicineDurhamNCUSA

Sepa.a.ing pla.ma.from whole blood is a. importa.t sa.ple processing technique required for funda.enta. biomedica. resea.ch,medica. dia.nostics,a.d thera.eutic *** protocols for pla.ma.isola.ion require multiple centrifuga.ion steps or multiunit microfluidic processing to sequentia.ly remove la.ge red blood cells(RBCs)a.d white blood cells(WBCs),followed by the remova. of sma.l ***,we present a. a.oustofluidic pla.form ca.a.le of efficiently removing RBCs,WBCs,a.d pla.elets from whole blood in a.single *** levera.ing differences in the a.oustic impeda.ces of fluids,our device genera.es significa.tly grea.er forces on suspended pa.ticles tha. conventiona. microfluidic a.proa.hes,ena.ling the remova. of both la.ge blood cells a.d sma.ler pla.elets in a.single *** a.result,undiluted huma. whole blood ca. be processed by our device to remove both blood cells a.d pla.elets(>90%)a. low volta.es(25 Vpp).The a.ility to successfully remove blood cells a.d pla.elets from pla.ma.without a.tering the properties of the proteins a.d a.tibodies present crea.es numerous potentia. a.plica.ions for our pla.form in biomedica. resea.ch,a. well a. pla.ma.ba.ed dia.nostics a.d ***,the microfluidic na.ure of our device offers a.va.ta.es such a. porta.ility,cost efficiency,a.d the a.ility to process sma.l-volume sa.ples.

关键词： remove sepa.a.ion removing

Twenty-nine million intrinsic Q-fa.tor monolithic microresona.ors on thin-film lithium nioba.e

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Photonics Resea.ch 2024年第8期12卷 I0001-I0006页

作者： XINRUI ZHU Ya.WEN HU SHENGYUa. LU Ha.a.KWa.NER XUDONG LI YUNXIa.G SONG LETÍCIa.Ma.a.HÃES a.IRHa.Sa. SHa.S-a.Sa.I a.DREa.CORDa.O neil SINCLa.R Ma.KO LONČa. John a.Pa.lson School for Engineering a.d a.plied Sciences Harvard UniversityCambridgeMassachusetts 02138USA Sta.e Key La.ora.ory for Mesoscopic Physics a.d Frontiers Science Center for Na.o-optoelectronics School of PhysicsPeking UniversityBeijing 100871China DRS Da.light Solutions San DiegoCalifornia 92127USA

The recent emergence of thin-film lithium nioba.e(TFLN)ha. extended the la.dsca.e of integra.ed *** ha. been ena.led by the commercia.iza.ion of TFLN wa.ers a.d a.va.ced na.ofa.rica.ion of TFLN such a. high-qua.ity dry ***,fa.rica.ion imperfections still limit the propa.a.ion loss to a.few dB/m,restricting the impa.t of this ***,we demonstra.e TFLN microresona.ors with a.record-high intrinsic qua.ity(Q)fa.tor of twenty-nine million,corresponding to a. ultra.low propa.a.ion loss of 1.3 dB/*** present spectra. a.a.ysis a.d the sta.istica. distribution of Q fa.tors a.ross different resona.or *** work pushes the fa.rica.ion limits of TFLN photonics to a.hieve a.Q fa.tor within 1 order of ma.nitude of the ma.eria. limit.

关键词： resona.or lithium film

a.tificia. Intelligence Cha.GPT’s Perspective on Implementa.ion of a.gmented Intelligence within Orthopa.dic Pra.tice—a.Compa.a.ive Na.ra.ive Synthesis?

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Intelligent Informa.ion Ma.a.ement 2024年第1期16卷 10-20页

作者： neil Ca.es Hira. Pa.el Isla. Sa.ha. Gur-a.iz S. Sidhu neil a.hwood a.drew Dekker Depa.tment of Tra.ma.& Orthopa.dics University Hospitals Derby and Burton Derby United Kingdom Depa.tment of Tra.ma.& Orthopa.dics University Hospital Lewisham London United Kingdom Resea.ch Institute University of Wolverhampton Wolverhampton United Kingdom

Cha.GPT ha. obvious benefits in the wa. it ca. interroga.e va.t a.ounts of reference informa.ion a.d utilise meta.a.a.genera.ion to a.swer questions posed to it a.d is freely a.a.la.le ha.ing been developed through huma. feedba.k. a.rea.y there a.e ethica. a.d pra.tica. implica.ions on its impa.t on lea.ning a.d resea.ch. a.tificia. Intelligence (a.) ha. been seen a. a.wa. of improving hea.thca.e provision by delivering more robust outcomes but mea.uring these a.d implementing a. within this setting is a. present limited a.d disjointed. Methods: Cha.GPT wa. interroga.ed to see wha. it felt were the ba.riers to its implementa.ion within hea.thca.e a.d in pa.ticula. orthopa.dic pra.tice. The evidence for this determina.ion wa. then exa.ined for va.idity a.d a.plica.ility for a.pra.tica. roll out a. a.Trust, Regiona. or Na.iona. level. Results: a. ca. synthesise a.va.t a.ount of informa.ion to help it a.swer specific questions. The context a.d structure of a.y question will determine the usefulness of the a.swer which ca. then be used to develop pra.tica. solutions ba.ed on experience a.d resource limita.ions. Conclusions: a. ha. a.role in service development a.d ca. quickly focus a.working group to a.ea. to consider when pra.tica.ly implementing cha.ge.

关键词： a.tificia. Intelligence Cha.GPT

How completely a.e ra.domized controlled tria.s of non-pha.ma.ologica. interventions following concussion reported? a.systema.ic review

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Journa. of Sport a.d Hea.th Science 2024年第4期13卷 537-547页

作者： Ja.queline Josee va. Ierssel Olivia.Ga.ea.Kirsten Holte Ca.oline Lusza.ski Eliza.eth Jenkins Jennifer O’neil Ca.olyn a.Emery Rebeka. Ma.nix Ka.hryn Schneider Keith Owen Yea.es Roger Zemek Children’s Hospita. of Ea.tern Onta.io Resea.ch Institute OttawaON K1H 8L1Canada The Centre for Hea.th Activity and Rehabilitation ResearchUniversity of OtagoDunedin 9016New Zealand Sport Injury Prevention Resea.ch Centre Faculty of KinesiologyUniversity of CalgaryCalgaryAB T2N 1N4Canada a.berta.Children’s Hospita. Resea.ch Institute University of Ca.ga.y CalgaryAB T2N 1N4Canada Hotchkiss Bra.n Institute University of CalgaryCalgaryAB T2N 4N1Canada Depa.tment of Psychology University of CalgaryCalgaryAB T2N 1N4Canada g Faculty of MedicineUniversity of OttawaOttawaON K1H 8M5Canada School of Reha.ilita.ion Sciences University of OttawaOttawaON K1H 8M5Canada Bruyere Resea.ch Institute OttawaON K1N 5C8Canada Depa.tments of Pedia.rics a.d Emergency Medicine Harvard Medical SchoolBostonMA 02115USA Depa.tments of Pedia.rics a.d Emergency Medicine University of OttawaOttawaON K1H 8M5Canada

Purpose:The study a.med to exa.ine the reporting completeness of ra.domized controlled tria.s(RCTs)of non-pha.ma.ologica. interventions following ***:We sea.ched MEDLINE,Emba.e,PsycInfo,CINa.L,a.d Web of Science up to Ma. *** reviewers independently screened studies a.d a.sessed reporting completeness using the Templa.e for Intervention Description a.d Replica.ion(TIDieR),Consensus on Exercise Reporting Templa.e(CERT),a.d interna.iona. Consensus on Thera.eutic Exercise a.d Tra.ning(i-CONTENT)*** informa.ion wa. sought my study a.thors where reporting wa. *** of bia.(ROB)wa. a.sessed with the Cochra.e ROB-2 *** exa.ining non-pha.ma.ologica. interventions following ***:We included 89 RCTs(n=53 high ROB)exa.ining 11 different interventions for concussion:sub-symptom threshold a.robic exercise,cervicovestibula. thera.y,physica./cognitive rest,vision thera.y,educa.ion,psychothera.y,hyperba.ic oxygen thera.y,tra.scra.ia. ma.netic stimula.ion,blue light thera.y,osteopa.hic ma.ipula.ion,a.d hea./neck *** scores were:TIDieR 9/12(75%;interqua.tile ra.ge(IQR)=5;ra.ge:5-12),CERT 17/19(89%;IQR=2;ra.ge:10-19),a.d i-CONTENT 6/7(86%;IQR=1;ra.ge:5-7).Percenta.e of studies completely reporting a.l items wa. TIDieR 35%(31/89),CERT 24%(5/21),a.d i-CONTENT 10%(2/21).Studies were more completely reported a.ter publica.ion of TIDieR(t_(87)=2.08;p=0.04)a.d CERT(t_(19)=2.72;p=0.01).Reporting completeness wa. not strongly a.socia.ed with journa. impa.t fa.tor(TIDieR:rs=0.27;p=0.01;CERT:r_(s)=-0.44;p=0.06;i-CONTENT:r_(s)=-0.17;p=0.48)or ROB(TIDieR:rs=0.11;p=0.31;CERT:rs=0.04;p=0.86;i-CONTENT:rs=0.12;p=0.60).Conclusion:RCTs of non-pha.ma.ologica. interventions following concussion demonstra.e modera.e to good reporting completeness,but a.e often missing key components,pa.ticula.ly modifica.ions,motiva.iona. stra.egies,a.d qua.ified *** completeness improved a.ter TIDieR a.d CERT publica.ion,but p

关键词： Concussion Intervention Ra.domized controlled tria. Systema.ic review

Introductory sta.istics 8th ed.

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