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Sustainable development of electroencephalography materials and technology

SusMat 2024年第2期4卷 125-144页

作者： Ling Xiong nannan Li Yi luo Lei Chen Institutes for Breast Health Medicine West China HospitalSichuan UniversityChengduChina Micro/Nano Fabrication Laboratory Microsystem and Terahertz Research CenterChina Academy of Engineering PhysicsChengduChina Institute of Electronic Engineering China Academy of Engineering PhysicsMianyangChina Department of Neurology Joint Research Institution of Altitude HealthWest China HospitalSichuan UniversityChengduChina

Electroencephalogram(EEG)is one of the most important bioelectrical signals related to brain activity and plays a crucial role in clinical *** by continuously expanding applications,the development of EEG materials and technology has attracted considerable ***,systematic analysis of the sustainable development of EEG materials and technology is still *** review discusses the sustainable development of EEG materials and ***,the developing course of EEG is introduced to reveal its significance,particularly in clinical ***,the sustainability of the EEG materials and technology is discussed from two main aspects:integrated systems and EEG *** integrated systems,sustainability has been focused on the developing trend toward mobile EEG systems and big-data monitoring/analyzing of EEG *** is related to miniaturized,wireless,portable,and wearable systems that are integrated with big-data modeling *** EEG electrodes and materials,sustainability has been comprehensively analyzed from three perspectives:performance of different material/structural categories,sustainablematerials for EEGelectrodes,and sustainable manufacturing *** addition,sustainable applications of EEG have been ***,the sustainable development of EEG materials and technology in recent decades is summarized,revealing future possible research directions as well as urgent challenges.

关键词： clinical medicine electroencephalography technology limitations and future directions materials and electrodes sustainable development

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Designable heteronanocrystals via interface redox reaction

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Nano Research 2023年第4期16卷 5946-5952页

作者： Zhihua Li Yang Li nannan luo Yuanyuan Qie Dingyi Yang Guowei Cao Yuxiang Liu Ying Fu Na Li Wen Hu Min Zhang Rusen Yang Bo Tang College of Chemistry Chemical Engineering and Materials ScienceKey Laboratory of Molecular and Nano ProbesMinistry of EducationCollaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of ShandongInstitute of Molecular and Nano ScienceShandong Normal UniversityJinan 250014China School of Advanced Materials and Nanotechnology Xidian UniversityXi'an 710126China

The synergistic interaction of different components in heteronanocrystals induces interfacial phenomena and novel ***,effective technologies to design and fabricate heteronanocrystals with materials on demand are still *** heterostructures in a copper patina are known to form at room temperature and under atmospheric *** redox process of copper tarnish inspired the discovery of a simple strategy to achieve heteronanocrystals that contained elements from group 3-11 and group *** interface redox-induced method is self-regulating at ambient conditions and applicable for metal,semiconductor,and dielectric *** enhanced interface bonding endows the heteronanocrystals with outstanding stability and catalytic performance,while the modular approach enables the design and fabrication of heteronanocrystals with intended materials to meet different purposes.

关键词： heteronanocrystals interface redox-induced synthesis modular approach

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构造正六面体表面混沌吸引子的平面迭代映射

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计算机辅助设计与图形学学报 2012年第4期24卷 443-450页

作者：陈宁罗囡囡沈阳建筑大学信息与控制工程学院沈阳110168

为了实现用二维迭代映射构造三维球面图形,提出用平面正方形格子上的迭代映射构造三维正六面体表面上连续排列的混沌吸引子的方法.首先提出用于构造正六面体上连续排列混沌吸引子的平面迭代映射在正方形格子上应满足的边界条件;其次用... 详细信息

为了实现用二维迭代映射构造三维球面图形,提出用平面正方形格子上的迭代映射构造三维正六面体表面上连续排列的混沌吸引子的方法.首先提出用于构造正六面体上连续排列混沌吸引子的平面迭代映射在正方形格子上应满足的边界条件;其次用截断的傅里叶三角级数构造出满足边界条件的3个平面排列迭代映射;最后找到了2个基本绘图窗口,利用3个迭代映射在2个正方形格子边界上的对称特性完成混沌吸引子在平面上和正六面体上的连续排列图形的构造.实验结果表明,文中提出的基于正方形格子的二维平面排列迭代映射可以用于大量的自动生成三维正六面体上的连续混沌吸引子图形.

关键词：平面排列对称映射正六面体混沌吸引子

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Probiotic Pediococcus pentosaceus restored gossypol-induced intestinal barrier injury by increasing propionate content in Nile tilapia

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1688-1703页

作者： Feifei Ding nannan Zhou Yuan luo Tong Wang Weijie Li Fang Qiao Zhenyu Du Meiling Zhang Laboratory of Aquaculture Nutrition and Environmental Health(LANEH) School of Life SciencesEast China Normal UniversityShanghai 200241China

Background Intestinal barrier is a dynamic interface between the body and the ingested food components, however, dietary components or xenobiotics could compromise intestinal integrity, causing health risks to the host. Gossypol, a toxic component in cottonseed meal(CSM), caused intestinal injury in fish or other monogastric animals. It has been demonstrated that probiotics administration benefits the intestinal barrier integrity, but the efficacy of probiotics in maintaining intestinal health when the host is exposed to gossypol remains unclear. Here, a strain(YC) affiliated to Pediococcus pentosaceus was isolated from the gut of Nile tilapia(Oreochromis niloticus) and its potential to repair gossypol-induced intestinal damage was *** A total of 270 Nile tilapia(2.20 ± 0.02 g) were allotted in 3 groups with 3 tanks each and fed with 3 diets including CON(control diet), GOS(control diet containing 300 mg/kg gossypol) and GP(control diet containing 300 mg/kg gossypol and 10^(8) colony-forming unit(CFU)/g P. pentosaceus YC), respectively. After 10 weeks, addition of P. pentosaceus YC restored growth retardation and intestinal injury induced by gossypol in Nile tilapia. Transcriptome analysis and si RNA interference experiments demonstrated that NOD-like receptors(NLR) family caspase recruitment domain(CARD) domain containing 3(Nlrc3) inhibition might promote intestinal stem cell(ISC) proliferation, as well as maintaining gut barrier integrity. 16S r RNA sequencing and gas chromatography-mass spectrometry(GC-MS) revealed that addition of P. pentosaceus YC altered the composition of gut microbiota and increased the content of propionate in fish gut. In vitro studies on propionate's function demonstrated that it suppressed nlrc3 expression and promoted wound healing in Caco-2 cell *** The present study reveals that P. pentosaceus YC has the capacity to ameliorate intestinal barrier injury by modulating gut microbiota composition and elevating

关键词： Gut barrier injury Gossypol ISCs proliferation Nlrc3 Propionate

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Potential-dependent insights into the origin of high ammonia yield rate on copper surface via nitrate reduction:A computational and experimental study

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Journal of Energy Chemistry 2024年第9期96卷 272-281页

作者： Yangge Guo nannan Sun Liuxuan luo Xiaojing Cheng Xueying Chen Xiaohui Yan Shuiyun Shen Junliang Zhang Institute of Fuel Cells School of Mechanical EngineeringMOE Key Laboratory of Power&Machinery EngineeringShanghai Jiao Tong UniversityShanghai 200240China Department of Chemical and Biological Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloon 999077Hong KongChina Paris Elite Institute of Technology Shanghai Jiao Tong UniversityShanghai 200240China

Focusing on revealing the origin of high ammonia yield rate on Cu via nitrate reduction(NO3RR),we herein applied constant potential method via grand-canonical density functional theory(GC-DFT)with implicit continuum solvation model to predict the reaction energetics of NO3RR on pure copper surface in alkaline *** potential-dependent mechanism on the most prevailing Cu(111)and the minor(100)and(110)facets were established,in consideration of NO_(2)_(−),NO,NH_(3),NH_(2)OH,N_(2),and N_(2)O as the main *** computational results show that the major Cu(111)is the ideal surface to produce ammonia with the highest onset potential at 0.06 V(until−0.37 V)and the highest optimal potential at−0.31 V for ammonia production without kinetic obstacles in activation energies at critical *** other minor facets,the secondary Cu(100)shows activity to ammonia from−0.03 to−0.54 V with the ideal potential at−0.50 V,which requires larger overpotential to overcome kinetic activation energy *** least Cu(110)possesses the longest potential range for ammonia yield from−0.27 to−1.12 V due to the higher adsorption coverage of nitrate,but also with higher tendency to generate di-nitrogen *** evaluations on commercial Cu/C electrocatalyst validated the accuracy of our proposed *** most influential(111)surface with highest percentage in electrocatalyst determined the trend of ammonia *** specific,the onset potential of ammonia production at 0.1 V and emergence of yield rate peak at−0.3 V in experiments precisely located in the predicted potentials on Cu(111).Four critical factors for the high ammonia yield and selectivity on Cu surface via NO3RR are summarized,including high NO3RR activity towards ammonia on the dominant Cu(111)facet,more possibilities to produce ammonia along different pathways on each facet,excellent ability for HER inhibition and suitable surface size to suppress di-nitrogen species formation at high nitrate cove

关键词： Nitrate reduction to ammonia Copper surface Density functional theory Constant electrode potential method Experimental validation

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Structures and ion transport mechanisms of plant high-affinity potassium transporters

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Molecular Plant 2024年第3期17卷 409-422页

作者： Jiangqin Wang Yanping luo Fan Ye Zhong Jie Ding Shao Jian Zheng Shuai Qiao Yong Wang Jiangtao Guo Wei Yang nannan Su international Institutes of Medicine the Fourth Affiliated HospitalZhejang University School of MedicineYiwuZhejiang 322000China Department of Biophysics and Department of Neurology of the Fourth Affiliated Hospital Zhejiang University School of MedicineHangzhouZhejang 310058China State Key Laboratory of Plant Environmental Resilience College of Life SciencesZhejang UniversityHangzhouZhejang 310058China College of Life Sciences Zhejiang UniversityHangzhouZhejiang 310058China NHC and CAMS Key Laboratory of Medical Neurobiology MOE Frontier Science Center for Brain Science and Brain-machine IntegrationSchool of Brain Science and Brain MedicineZhejiang UniversityHangzhouZhejiang 310058China Nanhu Brain-computer Interface Institute Hangzhou.Zheiang 311100.China

Plant high-affinity K^(+) transporters(HKTs)mediate Na^(+) and K^(+) uptake,maintain Na^(+)/K^(+) homeostasis,and therefore play crucial roles in plant salt *** this study,we present cryoelectron microscopy structures of HKTs from two classes,classI HKT1;1 from Arabidopsis thaliana(AtHKT1;1)and class II HKT2;1 from Triticum aestivum(TaHKT2;1),in both Na^(+) -and K^(+) -bound states at 2.6-to 3.0-A ***1;1and TaHKT2;1function *** HKT subunit consists of four tan-dem domain units(D1-D4)with a repeated K^(+) -channel-like M-P-M *** each subunit,D1-D4 assemble into an ion conduction pore with a pseudo-four-fold *** both TaHKT2;1and AtHKT1;1 have only one putative Na^(+) ion bound in the selectivity filter with a similar coordination pattern,the two HKTs display different K^(+) binding modes in the ***2;1 has three K^(+) ions bound in the selec-tivity filter,but AtHKT1;1 has only two K^(+) ions bound in the filter,which has a narrowed external entrance due to the presence of a Ser residue in the first filter *** structures,along with compu-tational,mutational,and electrophysiological analyses,enable us to pinpoint key residues that are critical for the ion selectivity of *** findings provide new insights into the ion selectivity and ion transport mechanisms of plant HKTs and improve our understanding about how HKTs mediate plant salt tolerance and enhance crop growth.

关键词： HKTs structure ion selectivity mechanism salt tolerance

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Mapping of powdery mildew resistance genes transferred to common wheat from wild emmer wheat revealed three functional Pm60 haplotypes

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The Crop Journal 2024年第2期12卷 540-548页

作者： Wenxin Wei nannan Liu Shengnan Zhang Jing Zhang Wei Pan Xiaoming Xie Zuhuan Yang Junna Sun Jun Ma Zhaorong Hu Weilong Guo Qiaoling luo Jingzhong Xie Fei He Yinghui Li Chaojie Xie Qixin Sun Key Laboratory of Crop Heterosis and Utilization(MOE)/Key Laboratory of Crop Genetic Improvement China Agricultural UniversityBeijing 100193China Institute of Advanced Agricultural Science Peking UniversityWeifang 261200ShandongChina Institute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100101China Triticeae Research Institute Sichuan Agricultural UniversityChengdu 611130SichuanChina Institute of Evolution University of HaifaMt.CarmelHaifa 3498838Israel

Powdery mildew(PM),caused by Blumeria graminis ***(Bgt),is one of the destructive wheat diseases *** emmer wheat(Triticum turgidum ***,WEW),a tetraploid progenitor of common wheat,is a valuable genetic resource for wheat disease resistance breeding *** developed three hexaploid pre-breeding lines with PM resistance genes derived from three WEW *** resistant pre-breeding lines were crossed with susceptible common wheat *** in the F2populations were 3 resistant:1 susceptible,suggesting a single dominant allele in each resistant *** of the resistance gene in each line indicated a single locus on the long arm of chromosome 7A,at the approximate location of previously cloned Pm60 from *** sequencing revealed three different Pm60 haplotypes(Hap 3,Hap 5,and Hap 6).Co-segregating diagnostic markers were developed for identification and selection of each *** resistance function of each haplotype was verified by the virus-induced gene silencing(VIGS).Common wheat lines carrying each of these Pm60 haplotypes were resistant to most Bgt isolates and differences in the response arrays suggested allelic variation in response.

关键词： Alleles Blumeria graminus Marker-assisted selection Molecular marker Triticum dicoccoides

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Cryptosporidiosis caused by Cryptosporidium parvum subtype IIdA15G1 at a dairy farm in Northwestern China

Cryptosporidiosis caused by Cryptosporidium parvum subtype I...

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中国畜牧兽医学会兽医寄生虫学分会第十三次学术研讨会

作者：崔朝辉王荣军 Jianying Huang Haiyan Wang Jinfeng Zhao nannan luo Junqiang Li Zhenjie Zhang 张龙现 College of Animal Science and Veterinary Medicine Henan Agricultural University International Joint Research Laboratory for Zoonotic Diseases of Henan

In October 2013,severe diarrhoea was observed in 396 pre-weaned calves at a farm in the Ningxia Autonomous Region of Northwestern China.356 of the infected calves died despite antibiotic therapy.252 faecal samples were collected from the investigated *** identity of Cryptosporidium species was determined by polymerase chain reaction(PCR) restriction fragment length polymorphism(RFLP) analysis,and by DNA sequence analysis of the small subunit(SSU) rRNA *** was subtyped using sequence analysis of the 60 kDa glycoprotein(gp60) *** highest infection rate of 83.3%(40/48) was seen in 2-3-week-old calves with diarrhoea,corresponding to the age at which animals *** Cryptosporidium species were identified,including ***(n = 51),***(n=1),and ***(n= 1).All *** isolates were further identified as subtype *** parvum was likely to be most responsible for diarrhoea and *** is the first report of a cryptosporidiosis outbreak caused by *** IIdA15G1 in Chinese dairy cattle.

关键词： Cryptosporidium parvum outbreak dairy cattle SSU rRNA gp60

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An engineered Cas12i nuclease that is an efficient genome editing tool in animals and plants

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The Innovation 2024年第2期5卷 61-69页

作者： Zhiqiang Duan Yafeng Liang Jialei Sun Hongjin Zheng Tong Lin Pengyu luo Mengge Wang Ruiheng Liu Ying Chen Shuhua Guo nannan Jia Hongtao Xie Meili Zhou Minghui Xia Kaijun Zhao Shuhui Wang Na Liu Yongling Jia Wei Si Qitong Chen Yechun Hong Ruilin Tian Jian-Kang Zhu Institute of Advanced Biotechnology and School of Medicine Southern University of Science and TechnologyShenzhen 518055China Bellagen Biotechnology Jinan 250000China Department of Medical Neuroscience School of MedicineKey University Laboratory of Metabolism and Health of GuangdongSouthern University of Science and TechnologyShenzhenGuangdong Province 518055China

The type V-I CRISPR-Cas system is becoming increasingly more attractive for genome ***,natural nucleases of this system often exhibit low efficiency,limiting their ***,we used structure-guided rational design and protein engineering to optimize an uncharacterized Cas12i nuclease,*** a result,we developed Cas-SF01,a Cas12i3 variant that exhibits significantly improved gene editing activity in mammalian ***-SF01 shows comparable or superior editing performance compared to SpCas9 and other Cas12 *** to natural Cas12i3,Cas-SF01 has an expanded PAM range and effectively recognizes NTTN and noncanonical NATN and TTVN *** addition,we identified an amino acid substitution,D876R,that markedly reduced the off-target effect while maintaining high on-target activity,leading to the development of CasSF01^(HiFi)(high-fidelity Cas-SF01).Finally,we show that Cas-SF01 has high gene editing activities in mice and *** results suggest that CasSF01 can serve as a robust gene editing platform with high efficiency and specificity for genome editing applications in various organisms.

关键词： system attractive rational

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Fe(Cu)/N改性TiO_2薄膜对盐酸四环素的光催化效果

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工业水处理 2018年第4期38卷 37-41页

作者：沈亨杰刘楠楠骆尚廉天津城建大学环境与市政工程学院天津300384 天津市水质科学与技术重点实验室天津300384

采用溶胶凝胶法及浸渍提拉法,制备了Fe/N、Cu/N共掺杂以及Fe、Cu、N单一离子掺杂改性的TiO_2薄膜,并进行SEM表征。在紫外光和太阳光照条件下,考察了改性TiO_2薄膜对盐酸四环素的光催化降解效果。结果表明:紫外光照下,Cu、N单一掺杂TiO_... 详细信息

采用溶胶凝胶法及浸渍提拉法,制备了Fe/N、Cu/N共掺杂以及Fe、Cu、N单一离子掺杂改性的TiO_2薄膜,并进行SEM表征。在紫外光和太阳光照条件下,考察了改性TiO_2薄膜对盐酸四环素的光催化降解效果。结果表明:紫外光照下,Cu、N单一掺杂TiO_2薄膜对盐酸四环素的降解效果较Fe/N、Cu/N共掺杂TiO_2薄膜的效果好。太阳光照下,Cu/N掺杂TiO_2薄膜对盐酸四环素的降解率达到69%,比其他改性TiO_2薄膜的降解效果要好,且制备条件简单易行。

关键词：共掺杂改性光催化二氧化钛盐酸四环素抗生素

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