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Contrasting strategies of optimizing carrier concentration in bulk InSe for enhanced thermoelectric performance

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Rare Metals 2024年第9期43卷 4425-4432页

作者： Hao-nan shi Shu-Lin Bai Yu-Ping Wang Li-Zhong Su Qian Cao Cheng Chang Li-Dong Zhao School of Materials Science and Engineering Beihang University School of Materials Science and Engineering Taiyuan University of Science and Technology Huabei Cooling Device Co.Ltd.

Indium selenide (InSe),as a wide-bandgap semiconductor,has received extensive attention in the flexible electronics field in recent years due to its exceptional plasticity and promising thermoelectric ***,the low carrier concentration severely limits its thermoelectric performance *** this work,we conducted contrasting strategies that can be employed to increase the carrier concentration of InSe,including bandgap narrowing and heterovalent ***,the carrier concentration initially increases as a result of the reduced bandgap upon Te alloying and then slightly decreases due to the weak electronegativity of *** Br doping realizes high carrier concentration by pushing the Fermi level into the conduction bands and activating the multiple *** the other hand,both Te and Br obviously suppress the thermal conductivity due to the point defect *** contrast,Br doping realizes a higher thermoelectric performance with a maximum ZT of～0.13 at 773 K benefiting from the better optimization of carrier *** work elucidates the strategies for enhancing carrier concentration at anion sites and demonstrates the high efficiency of halogen doping in ***,the carrier concentration of InSe is promising to be further optimized,and future work should focus on employing approaches such as cation doping or secondphase compositing.

关键词： Bandgap Carrier concentration Heterovalent doping InSe Thermoelectric

面向栓塞治疗的单分散高弹性可载药水凝胶微球的微流控制备及其性能研究

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高分子学报 2024年第3期55卷 328-337页

作者：施超男郭明雨苏州大学材料与化学化工学部新型功能高分子材料国家地方联合工程实验室、江苏省先进功能高分子材料设计及应用重点实验室、苏州市大分子设计与精密合成重点实验室苏州215123

面向栓塞治疗,利用单乳液毛细管微流控装置制备了粒径均一、尺寸可调节的载药弹性水凝胶微球.以丙烯酰胺(AM)和3-磺酸丙基甲基丙烯酸钾盐(SPMA)为单体,与光引发剂、自制大分子胶束多官能度交联剂(MM2),配制成水溶液作为分散相,以光引发... 详细信息

面向栓塞治疗,利用单乳液毛细管微流控装置制备了粒径均一、尺寸可调节的载药弹性水凝胶微球.以丙烯酰胺(AM)和3-磺酸丙基甲基丙烯酸钾盐(SPMA)为单体,与光引发剂、自制大分子胶束多官能度交联剂(MM2),配制成水溶液作为分散相,以光引发剂、表面活性剂溶于液体石蜡作为连续相,在微流控通道内得到单分散内相液滴,随后通过紫外光照交联聚合,生成具有优异弹性的水凝胶微球.三维通道内的压缩实验表明,微球被压缩约60%而不破碎,且可快速恢复原貌.微球能够快速并大量负载阳离子抗癌药物盐酸阿霉素,20 min即可达到载药平衡,且包封率均超过97%,平衡载药量约648 mg/g(干球)、95mg/g(湿球).此外,还对不同粒径载药微球在不同介质中的药物释放行为进行了研究探讨.研究结果为单分散、高弹性和高载药量水凝胶微球的制备,特别是在栓塞微球方面的潜在应用研究奠定了一定的基础.

关键词：微流控单分散微球弹性水凝胶微球栓塞微球

Radical innovation breakthroughs of biodegradation of plastics by insects:history,present and future perspectives

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Frontiers of Environmental Science & Engineering 2024年第6期18卷 127-165页

作者： Shan-Shan Yang Wei-Min Wu Federica Bertocchini Mark Eric Benbow Suja P.Devipriya Hyung Joon Cha Bo-Yu Peng Meng-Qi Ding Lei He Mei-Xi Li Chen-Hao Cui Shao-nan shi Han-Jun Sun Ji-Wei Pang Defu He Yalei Zhang Jun Yang Deyi Hou De-Feng Xing nan-Qi Ren Jie Ding Craig S.Criddle State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin 150090China Department of Civil and Environmental Engineering William&Cloy Codiga Resource Recovery CenterStanford UniversityStanfordCA 94305USA Plasticentropy rue Thiers 28Reims 51100France Department of Entomology and Department of Osteopathic Medical Specialties Michigan State UniversityEast LansingMI 48824USA School of Environmental Studies Cochin University of Science and TechnologyKochi 682022India Department of Chemical Engineering Pohang University of Science and TechnologyPohang 37673Republic of Korea School of Environmental Science and Engineering Tongji UniversityShanghai 200092China China Energy Conservation and Environmental Protection Group CECEP Talroad Technology Co.Ltd.Beijing 100096China School of Ecological and Environmental Sciences East China Normal UniversityShanghai 200241China Research Institute for Frontier Science Beihang UniversityBeijing 100191China School of Environment Tsinghua UniversityBeijing 100084China

Insects damaging and penetrating plastic packaged materials has been reported since the *** innovation breakthroughs of plastic biodegradation have been initiated since the discovery of biodegradation of plastics by Tenebrio molitor larvae in 2015 followed by Galleria mellonella in *** we review updated studies on the insect-mediated biodegradation of *** biodegradation by insect larvae,mainly by some species of darkling beetles(Tenebrionidae)and pyralid moths(Pyralidae)is currently a highly active and potentially transformative area of *** the past eight years,publications have increased explosively,including discoveries of the ability of different insect species to biodegrade plastics,biodegradation performance,and the contribution of host and microbiomes,impacts of polymer types and their physic-chemical properties,and responsible enzymes secreted by the host and gut *** date,almost all major plastics including polyethylene(PE),polypropylene(PP),polyvinyl chloride(PVC),polyethylene terephthalate(PET),polyurethane(PUR),and polystyrene(PS)can be biodegraded by *** and ten other insect species representing the Tenebrionidae and Pyralidae *** biodegradation processes are symbiotic reactions or performed by synergistic efforts of both host and gut-microbes to rapidly depolymerize and biodegrade plastics with hourly *** digestive ezymens and bioreagents screted by the insects play an essential role in plasatic biodegradation in certain species of Tenebrionidae and Pyralidae *** research on the insect itself,gut microbiomes,transcriptomes,proteomes and metabolomes has evaluated the mechanisms of plastic biodegradation in *** conclude this review by discussing future research perspectives on insect-mediated biodegradation of plastics.

关键词： Plastics Biodegradation Insects Gut microbiomes Enzymes

Targeting brain-derived neurotrophic factor in the treatment of neurodegenerative diseases:A review

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Neuroprotection 2024年第2期2卷 67-78页

作者： Dong Wang Zhi-Chen Lang shi-nan Wei Wei Wang Hao Zhang The Postgraduate Training Base of Jinzhou Medical University(The PLA Rocket Force Characteristic Medical Center) BeijingChina Department of Anesthesiology The PLA Rocket Force Characteristic Medical CenterBeijingChina

Neurodegenerative diseases,marked by the gradual death of neurons,present a significant and growing public health ***-derived neurotrophic factor(BDNF)is crucial for the survival,development,and synaptic plasticity of *** have consistently demonstrated that perturbed BDNF communication pathways are associated with the development and progression of neurodegenerative conditions,underscoring their potential as therapeutic *** review aimed to summarize the existing findings regarding BDNF expression,metabolism,and signaling ***,we reviewed the intricate roles of BDNF signaling pathways in neurodegenerative diseases,elucidating their contributions to disease onset and *** latest advancements in targeting BDNF for the treatment of neurodegenerative diseases,including the development of small molecules,nucleic acid-based therapeutics,and antibody-based approaches,were also *** recent strides,challenges persist,including a lack of comprehensive understanding of BDNF modulation across diverse neurodegenerative contexts and the absence of clinically approved BDNF-targeted drugs.

关键词： brain-derived neurotrophic factor central nervous system drug therapy gene therapy neurodegenerative diseases neuron

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论构建中国自主知识体系的两个前提性问题

学习与探索 2024年第6期 37-49页

作者：王南湜陕西师范大学哲学社会科学高等研究院南开大学哲学院

构建中国自主知识体系是中华民族伟大复兴不可或缺的根本性重要环节,亦是时代赋予知识生产者伟大而光荣的历史使命。由于长期以来西方文化在现代化进程中的支配性地位,构建中国自主知识体系的“自主”所意味者,不言而喻是对于西方文化... 详细信息

构建中国自主知识体系是中华民族伟大复兴不可或缺的根本性重要环节,亦是时代赋予知识生产者伟大而光荣的历史使命。由于长期以来西方文化在现代化进程中的支配性地位,构建中国自主知识体系的“自主”所意味者,不言而喻是对于西方文化的“自主”,因而基于中西文化的根本性差异,中国自主知识体系的构建必须解决两个前提性问题:首先必须确定作为中国文化核心价值理想之奠基的存在论视域问题;其次必须解决基于这一中国文化的存在论视域与作为现代社会之主干性支撑的现代科学之间是否可通达,以及如何通达的问题。

关键词：中国自主知识体系价值理想 “一体性”存在论视域 “二重复体性” 存在论视域

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Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese medicine and Western medicine

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Military Medical Research 2024年第3期11卷 313-322页

作者： Ying-Hui Jin Yan-Ping Wang Ying-Lan Xie Gui-Hua Tian Xiao-Yu Zhang nan-nan shi Ke-Hu Yang Xin Sun Yao-Long Chen Da-Rong Wu Xin-Feng Guo Long Ge Chen Zhao Cheng Lu Yin Jiang Jing Guo Si-Yu Yan Yong-Bo Wang Qiao Huang Xiang-Ying Ren Ying-Yue Rao Yun-Yun Wang Meng-Qian Yuan Xian-Tao Zeng Hong-Cai Shang Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China China Center for Evidence Based Traditional Chinese Medicine Beijing 100029China Hubei Provincial Hospital of Traditional Chinese Medicine Wuhan 430074China Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing Dongzhimen HospitalBeijing University of Chinese MedicineBeijing 100700China Evidence-Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhou 730000China China Center for Evidence-Based Medicine West China Hospital of Sichuan UniversityChengdu 610041China State Key Laboratory of Dampness Syndrome of Chinese Medicine the Second Affliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120China Evidence-based Medicine Team Guangdong Provincial Hospital of Traditional Chinese MedicineGuangzhou 510120China nanjing University of Chinese Medicine Nanjing 210023China Jiangsu Province Hospital of Chinese Medicine Nanjing 210029China

Integrated traditional Chinese medicine(TCM)and Western medicine(WM)is a new medical science grounded in the knowledge bases of both TCM and WM,which then forms a unique modern medical system in *** TCM and WM has a long history in China,and has made important achievements in the process of clinical diagnosis and ***,the methodological defects in currently published clinical practice guidelines(CPGs)limit its *** organic integration of TCM and WM is a deeper integration of TCM and *** realize the progression of"integration"to"organic integration",a targeted and standardized guideline development methodology is ***,the purpose of this study is to establish a standardized development procedure for clinical practice guidelines for the organic integration of TCM and WM to promote the systematic integration of TCM and WM research results into clinical practice guidelines in order to achieve optimal results as the whole is greater than the sum of the parts.

关键词： Methodology Traditional Chinese medicine Western medicine Organic integration Clinical practice guidelines(CPGs)

U-Pb dating of monazite in the Bainiuchang silver polymetallic deposit,Yunnan Province,and its limitation on Mesozoic mineralization

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China Geology 2024年第3期7卷 592-595页

作者： Bo-de Lu Wen-chang Li Xue-long Liu Guang-zhi Meng Qi-he Long Hong Zhang Jun-shan Dao Fang-lan Li Jie-hu Zhou Mao-huang Fan Xue Mi nan shi Zhen-liang Cao College of Land Resources and Engineering Kunming University of Science and TechnologyKunming 650093China Geological Team 306 of Yunnan Non-ferrous Metals Geological Bureau Kunming 650217China Mengzi Mining and Metallurgy Co. Ltd.Mengzi 661199China

*** The Gejiu-Bozhushan-Laojunshan tin-tungsten polymetallic metallogenic belt is located in southeastern *** is bounded by the Mile-shizong Fault and the Yangzi Plate to the north and west,respectively,while the Honghe Fault represents its southwestern *** is adjacent to the Ailaoshan Fault,and extends to Guangxi and Vietnam to the southeast(Fig.1a;Liu JP et al.,2021).

关键词： silver dating southeast

习近平新时代中国特色社会主义思想的理论之维

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山西师大学报（社会科学版） 2024年第3期51卷 46-50,83页

作者：方世南苏州大学马克思主义学院江苏苏州215006

习近平新时代中国特色社会主义思想是随着中国式现代化实践的深入推进而不断丰富发展的理论体系,是充分彰显学理化、体系化理论特质的马克思主义中国化时代化的理论创新成果。习近平新时代中国特色社会主义思想内涵十分丰富,由总体国家... 详细信息

习近平新时代中国特色社会主义思想是随着中国式现代化实践的深入推进而不断丰富发展的理论体系,是充分彰显学理化、体系化理论特质的马克思主义中国化时代化的理论创新成果。习近平新时代中国特色社会主义思想内涵十分丰富,由总体国家安全观、习近平强军思想、习近平经济思想、习近平生态文明思想、习近平外交思想、习近平法治思想、习近平文化思想所组成的理论学说,从整体性和多维性相统一、真理性和价值性相统一、理论性和实践性相统一的高度,彰显了作为世界观和方法论有机统一的理论体系的科学性、深刻性和完整性,在中华民族伟大复兴战略全局和世界百年未有之大变局的机遇和挑战并存的复杂态势下,深入回答了关系党和国家事业发展的一系列重大时代课题,是以中国式现代化全面推进中华民族伟大复兴的强大思想武器。

关键词：新思想理论特质世界观和方法论整体性和互动性问题导向和应答逻辑

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文化安全:把握习近平文化思想的重要维度

海南师范大学学报（社会科学版） 2024年第3期37卷 1-8,F0002页

作者：方世南苏州大学马克思主义学院江苏苏州215006 苏州大学东吴智库江苏苏州215006

习近平文化思想从其理论内容、显著特征、价值诉求、实践功能来看,也是关于文化安全的思想理论学说。从文化安全的维度把握习近平文化思想,有助于更全面地认识习近平文化思想形成和发展的深刻的时代背景,领悟习近平文化思想在推进文化... 详细信息

习近平文化思想从其理论内容、显著特征、价值诉求、实践功能来看,也是关于文化安全的思想理论学说。从文化安全的维度把握习近平文化思想,有助于更全面地认识习近平文化思想形成和发展的深刻的时代背景,领悟习近平文化思想在推进文化安全和确保总体国家安全方面的着力点。习近平文化思想从文化是一个国家和民族之灵魂的战略高度,将文化安全视为关乎国本、国运、民安的重大安全,将文化建设摆在治国理政的突出位置上谋划。习近平文化思想以其十分鲜明的文化安全的价值意蕴、以新时代肩负新的文化使命的强烈责任、以文化安全维护国家总体安全的价值诉求,以及在文化安全中建设中华民族现代文明的价值目标,为中国式现代化构筑起长治久安的钢铁长城指明了根本方向、提供了实践遵循。

关键词：习近平文化思想文化安全价值总体国家安全

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