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A randomized controlled trial of omega-3 fatty acids in dry eye syndrome

International Journal of Ophthalmology(English edition) 2013年第6期6卷 811-816页

作者： Rahul Bhargava Prachi Kumar Manjushrii Kumar namrata mehra Anurag Mishra Department of Ophthalmology Santosh Medical College and Hospital Department of Pathology Santosh medical College andHospital Department of Microbiology Narayan Medical College andHospital

AIM:To evaluate the role of dietary supplementation of omega-3 fatty acids in dry eye ***:A prospective,interventional,placebo controlled,double blind randomized trial was done at two referral eye *** hundred and sixty-four eyes of patients with dry eye were randomized to receive one capsule(500mg)two times a day containing 325mg EPA and 175mg DHA for 3 months(omega-3 group).The omega-3 group was compared to a group of patients(n=254)who received a placebo(placebo group).There were 4 patient visits(at baseline,1 month,2 months and3 months).On each visit,recording of corrected distance visual acuity(CDVA),slit lamp examination and questionnaire based symptom evaluation and scoring was done.A symptomatic score of 0-6 was mild,6.1-12moderate and 12.1-18 severe dry *** to intervention was monitored by routine tear function tests like Schirmer I test,tear film break-up time(TBUT),Rose Bengal staining and most notably,conjunctival impression ***:Sixty-five percent of patients in the omega-3group and 33%of patients in placebo group had significant improvement in symptoms at 3 months(P=0.005).There was a significant change in both Schirmer’s test value and TBUT values in the omega-3group(P<0.001),both ***,there was a larger drift in TBUT values in omega-3 than the placebo group,in comparison to Schirmer’s test *** mean TBUT score was 2.54±2.34 in the omega-3group and 0.13±0.16 in placebo group,*** mean reduction in symptom score in omega-3 group was 2.02±0.96 as compared to 0.48±0.22 in placebogroup(P<0.001).Despite a slight increase mean score,the Schirmer scores did not correlate well with symptomatic ***:Omega-3 fatty acids have a definite role for dry eye *** benefit seems to be more marked in conditions such as blepharitis and meibomian gland *** role of omega fatty acids in tear production and secretion needs further evaluation.

关键词： dry eye syndrome omega-3 fatty acids conjunctival impression cytology meibomian gland disease

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αB-crystallin mini-peptides support corneal healing in vitro and in vivo in rabbit model

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International Journal of Ophthalmology(English edition) 2024年第10期17卷 1772-1779页

作者： namrata Maity Aditya Konar Sarbani Hazra Department of Veterinary Surgery&Radiology West Bengal University of Animal and Fishery SciencesKolkata 700037India CSIR-IICB Kolkata 700032India

AIM:To evaluate if topical use ofαB-crystallin minipeptides supports corneal healing following flap ***:Cultured corneal cells were treated with fluorescent taggedαB-crystallin mini-peptides to assess its *** corneal cells pre-treated with or without the mini-peptides were exposed to H2O2 and cell viability was examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)*** of neurites of cultured trigeminal neurones was examined following treatment either withαB-crystallin mini-peptides or *** trigeminal neurones were pre-treated either withαB-crystallin mini-peptides or crystallin protein and exposed to H2O2 and presence of beading in the dendrites and axons was *** flap surgery was conducted on rabbit cornea and treated topically either withαB-crystallin peptide(0.5 mg/mL thrice daily for 14d)or phosphate-buffered saline(PBS).Corneal healing was evaluated under slit-lamp biomicroscope,mRNA expression of inflammatory cytokines were assessed and the corneas were evaluated by ***:Internalization ofαB-crystallin mini-peptides was ascertained by the detection of fluorescence within the corneal *** MTT assay revealed that treatment withαB-crystallin mini-peptide reduced cell death induced by H2O2 *** mini-peptides did not influence the elongation of trigeminal neurites,but significantly(P<0.05)reduced beading in the *** rabbit eye,the treated corneas showed reduced hyper-reflective zones(P<0.05)and suppression in the expression of inflammatory *** examination also revealed reduction of inflammatory response in treated ***:TheαB-crystallin mini-peptides restrict the damage to corneal cells and neurons and aids in corneal healing.

关键词： corneal healing αB-crystallin cytoprotection neuroprotection

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Bibliographic survey and comprehensive review on mechanical and durability properties of microorganism based self-healing concrete

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Frontiers of Structural and Civil Engineering 2024年第9期18卷 1445-1465页

作者： Md Marghoobul HAQUE Kunal M.SHELOTE namrata SINGH Supratic GUPTA Department of Civil Engineering Indian Institute of Technology DelhiNew Delhi 110016India

Concrete is the most widely utilized material for construction purposes,second only to water,in the ever-increasing need for construction *** is a brittle material and possesses a high risk of crack formation and consequent ***,which allows chemicals to enter and can cause concrete structures to lose their physico-mechanical and durability *** and rehabilitating concrete structures involves high costs and leads to various repair methods including coating,adhesives,polymers,supplementary cementitious materials(SCMs),and *** of the latest technologies is the use of microorganisms in *** added microorganisms lead to calcite precipitation and thereby heal the cracks *** study presents a comprehensive literature survey on bacteria-included concrete,before which a bibliographic survey is performed using VOSViewer *** addition to regular bacterial concrete,this study focuses on also using SCMs and fibers in bacterial concrete.A detailed literature review with data representation for various mechanical properties including compressive strength(CS),split tensile strength(SS),and flexure strength(FS),along with durability properties including carbonation,water absorption,resistance against chloride ion penetration,gas permeation,and resistance against cyclic freeze-and-thaw is presented.A study on the use of X-ray computed tomography(XCT)in bacterial concrete is highlighted,and the scope for future research,along with identification of the research gap,is presented.

关键词： bacterial concrete bibliographic survey biomineralization carbonation fibers

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Diverting agents in the oil and gas industry:A comprehensive analysis of their origins,types,and applications

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Petroleum Research 2024年第1期9卷 72-84页

作者： namrata Bist Abhishek Nair Kriti Yadav Anirbid Sircar Pandit Deendayal Energy University GandhinagarGujarat382007India Department of Geology Patna UniversityAshok RajpathPatna800005India

During the life of a well,treatments are carried out to boost productivity by stimulating initially unproduced *** treatments include hydraulic fracturing,matrix acidization,and acid fracturing,among *** fracturing treatment is generally applied to deeper reservoirs of oil or natural gas for enhanced *** infusing proppant,water,and chemicals under extreme pressure during the fracturing procedure,fissures in and beneath the reservoir layer can be accessed and *** stimulating procedure,matrix acidization,involves injecting acid down the drilling hole to permeate the rock fissures at stresses lower than the fracture *** addition,carbonate reservoir acid fracturing stimulation is commonly used as an acid treatment technique whereby a pressure greater than the formation disintegration pressure or spontaneous fracture closure pressure is used to compress acid into the *** treatments allow existing wells to sustain hydrocarbon production without new wells being ***,when employed efficiently,can prevent the need to use a rig to provide momentary physical barriers,thus lowering the cost of the *** improvements in diversion technology make use of a variety of degradable particles that act as momentary bridges,either at the perforation entries or inside the existing *** aim of this study is to introduce different types of mechanical and chemical diverters used to enhance the productivity of *** study explains the concepts of different types of diverters and their applications in several formations,it will also help readers to understand the selection procedures based on the suitability and requirements of diverter use by case studies from around the world.

关键词： Refracturing Well treatment Chemical diverter Mechanical diverter Acid fracturing

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Clinical outcomes of triceps reflecting anconeus pedicle and olecranon osteotomy approach for distal humerus intercondylar fractures

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World Journal of Orthopedics 2024年第6期15卷 570-577页

作者： Rohit Ailani Sanjeev Kumar Bhuyan Brejesh Kumar Prasad Amit Kumar namrata Dawani Department of Orthopaedics Lovee Shubh HospitalLucknowUttar Pradesh 226002India Department of Orthopaedics Gauhati Medical CollegeGuahati 781032India Department of Orthopaedics ESIC Medical College and HospitalFaridabadHaryana 121001India Department of Orthopaedics All India Institute of Medical SciencesKalyaniWest Bengal 741245India Department of Obstetric and Gynecology Kannauj Medical CollegeKannaujUttar Pradesh 209732India

BACKGROUND The preferred treatment for distal humeral intercondylar fractures is open reduction and internal *** there is consensus about the posterior approach,several posterior approaches have been *** is debatable as to which approach is *** To compare triceps reflecting anconeus pedicle(TRAP)and olecranon osteotomy approaches for internal fixation of distal humeral intercondylar *** In total,40 cases of Arbeitsgemeinschaft für Osteosynthesefragen/Association of the Study of Internal Fixation type C,closed,and Gustilo type I intercondylar humeral fractures were *** ranged in age from 18 years to 70 *** patients were randomized into two groups:TRAP group and olecranon osteotomy group,with 20 cases in *** were followed up at 6 wk,3 months,6 months,and 12 *** outcomes were measured in terms of flexion-extension arc,Disabilities of Arm,Shoulder and Hand score,and Mayo Elbow Performance *** The mean age was 43.2 years in the TRAP group and 37.5 years in the olecranon osteotomy *** mean operative time and mean duration of hospital stay in the TRAP group were significantly higher than in the olecranon osteotomy group(119.5 vs 111.5 min and 9.85 vs 5.45 d,respectively).The mean arc of flexion-extension,Disabilities of Arm,Shoulder and Hand score,and Mayo Elbow Performance Score were comparable without any significant difference in the groups at the 12-month follow-up(107.0 vs 106.2,18.3 vs 15.7,and 84.2 vs 86.2,respectively).Ulnar paresthesia and superficial infections were comparable in both groups(2 cases vs 3 cases and 3 cases vs 2 cases,respectively).Hardware prominence was significantly higher in the olecranon osteotomy group,mostly due to tension band *** Both approaches were equivalent,but there is a need for further study including higher numbers of subjects and longer study duration to prove the benefits of one approach over the other.

关键词： Elbow joint Humeral fracture Osteotomy Internal Fracture fixation

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Comprehensive analysis of uncertainty quantification for the^(58)Ni(n,p)^(58)Co reaction cross section

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Chinese Physics C 2024年第9期48卷 170-175页

作者： Mahesh Choudhary Aman Sharma namrata Singh Mahima Upadhyay Punit Dubey A.Gandhi Akash Hingu G Mishra Sukanya De L.S.Danu Ajay Kumar R.G.Thomas Saurav Sood Sajin Prasad S.Mukherjee I.N.Ruskov Yu.N.Kopatch A.Kumar Department of Physics Banaras Hindu UniversityVaranasi 221005India Horia Hulubei National Institute of Physics and Nuclear Engineering-IFIN-HH Bucharest 077125Romania Department of Physics The Maharaja Sayajirao University of BarodaVadodara 390002India Nuclear Physics Division Bhabha Atomic Research CentreMumbai 400085India Health Physics Division Bhabha Atomic Research CentreMumbai 400085India Department of Electrical Power Engineering Brno University of TechnologyBrno 61600Czech Republic Institute for Nuclear Research and Nuclear Energy Bulgarian Academy of SciencesSofia 1784Bulgaria Joint Institute for Nuclear Research(JINR) Dubna 141980Russia

In this study,we measured the^(58)Ni(n,p)^(58)Co reaction cross section with neutron energies of 1.06,1.86,and 2.85 *** cross section was measured using neutron activation techniques andγ-ray spectroscopy,and it was compared with cross section data available in the ***,we calculated the covariance matrix of the measured cross section for the aforementioned nuclear *** uncertainties of the theoretical calculation for^(58)Ni(n,p)^(58)Co reaction cross section were calculated via Monte Carlo *** this study,we used uncertainties in the optical model and level density parameters to calculate uncertainties in the theoretical cross *** theoretical calculations were performed by using *** this study,we aim to analyze the effect of uncertainties of the nuclear model input as well as different experimental variables used to obtain the values of reaction cross section.

关键词： ^(58)Ni(n p)^(58)Co reaction γ-ray spectroscopy uncertainty quantification of cross section covariance analysis

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Assessing the bioremediation potential of arsenic tolerant bacterial strains in rice rhizosphere interface

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Journal of Environmental Sciences 2016年第10期28卷 112-119页

作者： namrata Singh Shubhi Srivastava Sushma Rathaur Nandita Singh Eco-auditing Group CSIR-National Botanical Research Institute Lucknow 226001 India Department of Biochemistry Banaras Hindu University Varanasi 221001 India

The arsenic tolerant bacterial strains Staphylococcus arlettae （NBRIEAG-6）, Staphylococcus sp. （NBRIEAG-8） and Brevibadllus sp. （NBRIEAG-9） were tested for their roles in enhancing plant growth and induction of stress-related enzymes in rice （Oryza sativa L. cv. NDR-3Bg） plants at two different concentrations, 30 and IS mg/kg of As（V） and As（Ⅲ）, respectively. An experiment was conducted to test the effect of these strains on plant growth promotion and arsenic uptake. We found 30%-40% reduction in total As uptake in bacteria-inoculated plants, with increased plant growth parameters compared to non-inoculated plants. Moreover, the bacteria-inoculated plants showed reduced activity of total glutathione （GSH） and glutathione reductase （GR） compared to their respective controls, which suggests the bacteria-mediated reduction of oxidative stress in plants. Thus, these strains were found to be beneficial in terms of the biochemical and physiological status of the plants under arsenic stress conditions. Furthermore, one-way ANOVA and principal component analysis （PCA） on enzymatic and non-enzymatic assays also revealed clear variations. The results support the distinction between control and treatments in both shoots and roots. Therefore, this study demonstrates the potential of rhizobacteria in alleviating arsenic stress in rice plants.

关键词： Antioxidative enzymeOryza satiua L.Environmental contaminationMetalsSoil bacteria

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Carbon mitigation using CarbFix,CO_(2)plume and carbon trading technologies

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能源地球科学(英文) 2023年第1期4卷 117-130页

作者： Kriti Yadav Anirbid Sircar namrata Bist Centre of Excellence for Geothermal Energy Pandit Deendayal Energy UniversityGandhinagarGujarat382007India School of Petroleum Technology Pandit Deendayal Energy UniversityGandhinagarGujarat382007India

Following China and the United States,India is the third highest CO_(2)emitter in the *** its fast rising population and an industry primarily reliant on coal and oil,the country's emissions will continue to rise unless appropriate measures are *** India generally the carbon sequestration is done by storing CO_(2)in sedimentary basins where it gets capped by the impermeable cap *** study aims to unfold the other techniques of carbon sequestration in subsurface formations,except for narrating the different types of carbon capture and sequestration techniques along with its storage in different types of *** instance,abiotic and biotic environments for CO_(2)*** further talks about carbon injections of oceanic,geological,and terrestrial types,to name just a *** of carbon emission sources are discussed *** this paper three different approaches are described for carbon mitigation,namely CarbFix,CO_(2)Plume technology and Carbon Trading.A prefeasibility study was done in order to implement the three techniques in Dholera geothermal region in Gujarat,*** literature review,it can be seen how the three techniques can help in permanent mitigation of captured carbon through carbonate mineralization,power generation and industrial *** any project government and public participation is *** this regard the study gives a brief understanding about the steps to be taken by government and the public to promote such projects for carbon ***,the steps to be taken in such projects for health and risk assessment were talked about in literature review too.

关键词： Carbon capture CarbFix Carbon trading Greenhouse gas Geothermal region in Dholera

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Investigation of 58Ni(n, p)58Co reaction cross-section with covariance analysis

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Chinese Physics C 2024年第2期48卷 78-90页

作者： Akash Hingu S.Mukherjee Siddharth Parashari Arora Sangeeta A.Gandhi Mahima Upadhyay Mahesh Choudhary Sumit Bamal namrata Singh G.Mishra Sukanya De Saurav Sood Sajin Prasad G.Saxena Ajay Kumar R.G.Thomas B.K.Agrawal K.Katovsky A.Kumar Department of Physics Faculty of ScienceThe M.S.University of BarodaVadodara 390002India Faculty of Electrical Engineering and Communication Brno University of TechnologyBrnoCzech Republic Department of Physics Faculty of ScienceUniversity of ZagrebBijenička c.32Zagreb 10000Croatia Department of Physics University Institute of SciencesChandigarh UniversityGharuanMohali 140413PunjabIndia Department of Physics Banaras Hindu UniversityVaranasi 221005India Horia Hulubei National Institute for Physics and Nuclear Engineering Măgurele 077125Romania Nuclear Physics Division Bhabha Atomic Research CentreMumbai 400085India Health Physics Division Bhabha Atomic Research CentreMumbai 400085India Department of Physics(H&S) Government Women Engineering CollegeAjmer 305002India Saha Institute of Nuclear Physics Kolkata 700064India Homi Bhabha National Institute Anushakti NagarMumbai 400094India

The excitation function of the 58Ni(n,p)58Co reaction was measured using the well-established neutron activation technique andγ-ray *** in the energy range of 1.7 to 2.7 MeV were generated using the 7Li(p,n)*** neutron flux was measured using the standard 115In(n,n’)115mIn monitor *** results of the neutron spectrum averaged cross-section of 58Ni(n,p)58Co reactions were compared with existing cross-section data available in the EXFOR data library as well as with various evaluated data libraries such as ENDF/B-VIII.0,JEFF-3.3,JENDL-4.0,and *** calculations were performed using the nuclear reaction code *** nuclear level density(NLD)models were tested,and their results were compared with the present *** NLDs were also obtained through the spectral distribution method(SDM).The cross-section results,along with the absolute errors,were obtained by investigating the uncertainty propagation and using the covariance *** forγ-ray true coincidence summing,low-energy background neutrons,andγ-ray self attenuation were *** experimental cross-section obtained in the present study is consistent with previously published experimental data,evaluated libraries,and theoretical calculations carried out using the TALYS code.

关键词： nuclear reactions (n,p)reaction cross-section measurement covariance analysis nuclear level density

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Digital twin in hydrocarbon industry

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Petroleum Research 2023年第2期8卷 270-278页

作者： Anirbid Sircar Abhishek Nair namrata Bist Kriti Yadav Centre of Excellence for Geothermal Energy Raisan382007GandhinagarGujaratIndia

The hydrocarbon industry is considering a range of digital technologies to improve productivity,efficiency,and safety of their operations while minimizing capital and operating costs,health and environmental risks,and variability in oil and gas project life *** to the emergence of industry 4.0 the improvement in performance,efficiency,and cost reduction,the hydrocarbon industry is gradually shifting towards solutions that are *** such complex systems involves the analysis of data from various sources at the same *** Twin(DT)modelling is the foundation for the next generation of real-time production monitoring and optimization *** is a solution that boosts productivity by combining information,simulation,and visualization throughout the entire value chain of an operational firm,from subsurface equipment to central production *** and gas companies can majorly benefit from Hydrocarbon Exploration with the right use of such advanced *** study focuses on the advancements in technology in the context of DT and how it has been used by the hydrocarbon *** study discusses about the emergence of the DT concept,various types,5D representation,and tools for ***,the study tries to implement fields of DT in hydrocarbon industry especially in the domains of exploration,drilling,and *** associated with DT strategy like accessibility,confidentiality integration,and maintenance are also discussed.

关键词： Digital twin technology Hydrocarbon exploration Industry 4.0 Oil and gas Digitalization Automation

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