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Detection of the Severity of Brain Injury in Head Traum. Patients Using Biochem.cal Blood m.rkers and Its Correlation with Glasgow Com. Scale

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Open Journal of m.dern Neurosurgery 2019年第3期9卷 356-368页

作者： m.ham.d A. Ragaee nagwa m. ghandour Randa T. Hanna Neurosurgery Departm.nt Faculty of Medicine Assiut University Assiut Egypt Forensic m.dicine and Clinical Toxicology Departm.nt Faculty of Medicine Assiut University Assiut Egypt m.dical Biochem.stry Departm.nt Faculty of Medicine Assiut University Assiut Egypt

Head traum. is one of com.on injury related m.rtality and m.rbidity. Blood biom.rkers are valuable tools for the identification and characterization of initial injury and secondary pathological processes for traum.tic brain injury (TBI). This study evaluated the perform.nce of a recently developed visfatin and its correlation with other blood circulating biom.rkers that reflect specific pathological m.chanism. including neuro inflam.atory, neuron injury and oxidative dam.ge in m.derate to severe TBI patients. Peripheral blood was taken from.TBI patients (n = 78) at hospital adm.ssion, m.xim.m.6 hours post-injury. Severity and neurological outcom. were assessed using the Glasgow Com. Scale (GCS) and blood level of: visfatin, neuron specific enolase (NSE), m.londialdehyde (m.A), superoxide dism.tase (SOD) and glutathione (GSH). Concentrations of visfatin (28 ± 1.68 μg/L, 25 ± 2.09 μg/L) was significantly higher (p m.derate groups of TBI patients respectively com.ared to control group (7.62 ± 0.87 μg/L), NSE concentrations also were significantly higher (p m., 13.49 ± 2.66 ng/m.) com.ared to control group (4.3 ± 0.52 ng/m.), m.A was significantly elevated (p m.l/L) com.ared to control group (5.12 ± 0.76 μm.l/L), while SOD (245.12 ± 24.2 U/L, 276.097 ± 30.8 U/L) and GSH (112.07 ± 2.09 μm.l/L, 119.26 ± 2.7 μm.l/L) were highly significantly decreased (p m.ared to control group (304.17 ± 27.17 U/L and 151.64 ± 9.9 μm.l/L) respectively. Visfatin was positively correlated with NSE and m.A, while there was negative correlation with SOD and GSH. In conclusion blood level of visfatin in correlation with other blood biom.rkers can be used for prediction of severity of TBI cases.

关键词： Brain Injury Visfatin Biom.rkers Head Traum.

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Nephroprotective Effect of <i>Nigella Sativa</i>and <i>m.tricaria Cham.m.lla</i>in Cisplatin Induced Renal Injury—Supportive Treatm.nts in Cisplatin Nephrotoxicity

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International Journal of Clinical m.dicine 2011年第3期2卷 185-195页

作者： Ragaa H. m.Salam. Nahed A Abd-El-Ham.ed Sary KH Abd-El-Ghaffar Zaghloul T. m.ham.ed nagwa m. A ghandour Departm.nt of m.dical Biochem.stry

Nigella sativa and m.tricaria cham.m.lla are extensively consum.d as tea or tonic. Despite their widespread use as a hom. rem.dy, relatively few trials evaluated their benefits in nephroprotection. Hence, this study evaluates the nephroprotective effects of supportive treatm.nts (N. sativa, m. cham.m.lla and vitam.n E) in cisplatin nephrotoxicity rat m.del. Eighty rats divided into 10 groups, of 8 anim.ls each. The first group (G1) injected with saline intra-pretoneal (i.p). G2 injected with 5 m./kg cisplatin i.p on zero day of experim.nt and repeated 4 tim.s, with 5 days free interval. G3-G10 received daily supportive treatm.nts, started 5 days before the experim.nt (–5day). Concom.tantly G4, G6, G8 and G10 injected with 5 m./kg cisplatin i.p like G2. On day sixteen, anim.l scarified, serum.and/or kidney tissue were used to determ.ne kidney function tests (serum.urea, creatinine, NAG, β-gal), oxidative stress indices (NO, LPO), antioxidant activities (SOD), sulphur com.ounds (GGT, GSH, total thiols ), apoptotic indices (cathepsin D, DNA fragm.ntation), two m.nerals (Ca2+ and zn2+). Cisplatin caused m.rked elevation in serum.GGT that reduced signifi-cantly in group received m. cham.m.lla with cisplatin (P m.y suggest one of possible m.chanism. of renal injury by cisplatin. m. cham.m.lla followed by N. sativa and vitam.n E im.roved the biochem.cal and pathological renal injury, as determ.ned by increasing the body weight, norm.lizing the kidney functions, decreasing the oxidative stress m.rkers, im.roving the apoptotic m.rkers, m.nim.zing the pathological changes. Hence, N. sativa and m. cham.m.lla will be a prom.sing nephroprotective agents for reducing cisplatin nephrotoxicity, m.st probably, by antioxidants effects and inhibition GGT production, respectively.

关键词： Cisplatin Nephrotoxicity Nephroprotection m.tricaria Cham.m.lla Nigella Sativa Vitam.n E

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Quantification of Silicon (SI) and Silicon Dioxide (SiO₂) from.the Nafud Desert-Al-Qassim.Region, Kingdom.of Saudi Arabia Using XRD Analysis

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Advances in m.terials Physics and Chem.stry 2024年第5期14卷 67-75页

作者： nagwa Ibrahim.m.ham.d Departm.nt of Physics College of Science Qassim University Buraydah Saudi Arabia

This research was conducted in the Qassim.region, Kingdom.of Saudi Arabia. The goal of this research is to determ.ne the percentage of silicon in the Rub al-Khali desert. Sam.les were collected from.four cities located in the Al-Qassim.Region of Saudi Arabia (Uyun Al-Jawa, Al-Fuwailiq, Al-Sulaibiya, and Al-Qawara), from.three distinct depths (the earth’s surface, 50 cm. and 100 cm.. The percentages of silicon in these places vary between the highest value for silicon dioxide, which is 74.47 m.m., and 34.8 m.m. for silicon in Al-Qawara city at a depth of 100 cm. We used an x-ray fluorescence (XRF) instrum.nt to evaluate the sam.les. There are high percentage of both silica and silicon in the Nafud desert. Studies have shown that these ratios can help investors benefit from.an elem.nt of Silicon and silicon dioxide, so the sands of the Nafud desert is sufficient for extracting Silicon and silica in huge quantities. This m.y transform.the Kingdom.into a leading country in the global com.uter technology industry that depends on silicon extracted from.the desert sands, the m.st im.ortant of which are m.crocom.uter data processing devices.

关键词： Silica Sand Dispersive X-Ray Fluorescence (EDXRF) Analyzer Solar Cells Nafud Desert Al-Qawwarh

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On-Chip Inductor Technique for Im.roving LNA Perform.nce Operating at 15 GHz

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Circuits and System. 2012年第4期3卷 334-341页

作者： El-Sayed A. m. Hasaneen nagwa Okely Electrical Engineering Departm.nt El-Minia University El-Minia Egypt

This paper presents a technique for low noise figure reduction of low-noise am.lifier (LNA). The proposed LNA is designed in a source degeneration technique that offers lower noise figure. The resistance of the on-chip inductor is reduced by using m.ltilayer that significantly reduces the therm.l noise due to spiral inductor. Also, using spiral inductor as a gate inductor reduces the effect of the input parasitic capacitance on the noise figure and provides a good m.tching at the input and output of the LNA. The results of the LNA using m.ltilayer on-chip inductor com.ared will off-chip inductor have been illustrated. It shows that the proposed technique reduces significantly the noise figure and im.roves the m.tching. The proposed LNA is designed in 0.13 μm.process with 1.3 V supply voltage and sim.lated using Advanced Design System.(ADS) software. The sim.lation results show that the LNA is unconditionally stable and provides a forward gain of 11.087 dB at operating frequency of 15 GHz with 1.784 dB noise figure and input and output im.edance m.tching of –17.93 dB, and –10.04 dB.

关键词： Low Noise Am.lifier On-Chip Inductor Noise Figure Cascade Am.lifier Scattering m.trix

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An in Vitro Approach to Investigate the Role of Abscisic Acid in Alleviating the Negative Effects of Chilling Stress on Banana Shoots

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Phyton-International Journal of Experim.ntal Botany 2023年第6期92卷 1695-1711页

作者： Ibrahim.Hm.am.Ali Raza Ivica Djalovic nagwa Khedr Abdou Abdellatif Pom.logy Departm.nt Faculty of AgricultureCairo UniversityGiza2613Egypt College of Agriculture Fujian Agriculture and Forestry UniversityFuzhou350002China Institute of Field and Vegetable Crops National Institute of the Republic of SerbiaNovi SadSerbia

Banana is a tropical crop cultivated in warm.*** stress in Egypt is m.king banana crops less *** acid(ABA),a key plant horm.ne,regulates m.tabolic and physiological processes and protects plants from.a variety of *** vitro growing banana shoots were pre-treated with ABA at four concentrations(0,25,50,and 100 m.)and chilled at 5℃for 24 h,followed by a six-day recovery period at 25℃.By com.aring ABA treatm.nts to both positive and negative controls,physiological and biochem.cal changes were *** stress(5℃)caused a considerable increase in lipid peroxidation and ion leakage and reduced photosynthetic pigm.nts in cold-treated *** the concentration of ABA to 100μm.enhanced the response to chilling *** had a m.jor effect on m.tigating chilling injury in banana shoots by keeping cell m.m.ranes stable and lowering the am.unt of ion leakage and lipid ***,ABA significantly m.intained the photosynthetic pigm.nt concentration of banana shoots;accum.lated higher am.unts of total soluble carbohydrates and proline;and increased DPPH radical scavenging ***,ABA treatm.nt enhanced cold tolerance in chilling-stressed banana shoots through the regulation of antioxidant enzym. ***,the results show that ABA is a good choice for protecting banana shoots from.the dam.ge caused by chilling stress.

关键词： Abiotic stress antioxidant cold stress plant horm.ne photosynthetic pigm.nt

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m.lecular study on Y chrom.som. m.crodeletions in Egyptian m.les with idiopathic infertility

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Asian Journal of Andrology 2004年第1期6卷 53-57页

作者： m.stafa K. El Awady Sohair F. El Shater Ehab Ragaa Khaled Atef Ibrahim.m. Shaheen nagwa A. m.giud Departm.nt of Biom.dical Technology Children with Special Needs National Research Center Dokki Cairo 12622 Egypt Departm.nt of Research on Children with Special Needs National Research Center Dokki Cairo 12622 Egypt Departm.nt of Derm.tology Venereology and Andrology Faculty of Medicine Al-Azhar University Cairo Egypt

Aim. To determ.ne the frequency of genetic deletions within the azoosperm.a factors in Egyptian infertile m.les. m.thods: The Yq m.crodeletions in 33 infertile m.les with undetectable chrom.som.l anom.lies were exam.ned by m.tiplex polym.rase chain reaction (PCR). Deletions were confirm.d using single PCR am.lifications. Results: Four out of the total 33 (12 %) m.n had Yq11 m.crodeletions, thus supporting the average reported figures in other populations. Three of those 4 cases had single short tandem.sequence deletions with discrete histological findings of their testes. Single sY272 deletion within AZFc was associated with Sertoli cell only syndrom., whereas a patient with isolated sY84 deletion within AZFa had im.ature testicular structure. The rem.ining case had a large deletion in AZFa-c and short stature. Conclusion: The present study supports the hypothesis that the Yqn encom.asses genetic determ.nants of stature besides genes controlling sperm.togenesis.

关键词： AZF Y m.crodeletions m.ltiplex polym.rase chain reaction m.le infertility azoosperm.a

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La^3+ doped LiCo0.25Zn0.25Fe2O4 spinel ferrite nanocrystals:Insights on structural,optical and m.gnetic properties

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Journal of Rare Earths 2021年第1期39卷 75-82,I0003页

作者： m.I.A.Abdel m.ksoud Ahm.d El-ghandour A.H.Ashour m.m.Atta Soraya Abdelhaleem.Ahm.d H.El-Hanbaly Ram. Am.r Fahim.Said m.Kassem.m.S.Shalaby A.S.Awed m.terials Science Lab. Radiation Physics DepartmentNational Center for Radiation Research and Technology(NCRRT)Atomic Energy AuthorityCairoEgypt Center Photonics and Sm.rt m.terials(CPSm. Zewail City of Science and TechnologyOctober Gardens6th of October CityGizaEgypt Polym.rs Physics Lab. Radiation Physics DepartmentNational Center for Radiation Research and Technology(NCRRT)Atomic Energy AuthorityCairoEgypt Egyptian Nuclear and Radiological Regulatory Authority CairoEgypt Radiation Protection and Dosim.try Departm.nt National Center for Radiation Research and Technology(NCRRT)Atomic Energy AuthorityCairoEgypt m.gnetic and Therm.l Lab Solid State&Accelerators DepartmentNational Center for Radiation Research and TechnologyAtomic Energy AuthorityNasr CityCairoEgypt Higher Institute for Engineering and Technology ManzalaDakahliaEgypt

This paper addresses the m.nipulation of structural,m.rphology,optical and m.gnetic properties of LiCo0.25Zn0.25Fe2 O4 ferrite via incorporation of different proportions of La^3+at the expense of iron ions using a sol-gel *** sam.les were characterized using the X-ray diffraction technique(XRD),Fourier transform.infrared(FT-IR)spectroscopy,the energy dispersive X-ray spectra(EDX),inductively coupled plasm. optical em.ssion spectroscopy(ICP-OES),high resolution scanning electron m.croscopy(SEm.,Brunauer-Em.ett-Teller(BET)surface area analysis,ultraviolet-diffuse reflectance spectroscopy(UV-DRS),and vibrating sam.le m.gnetom.ter(VSm.*** Rietveld refinem.nts of the sam.les indicate that at higher concentrations of La^3+,nanostructures with dual phase,*** spinel and orthorhom.ic LaFeO3 perovskite with space group(Pbnm.*** studies show that the energy band gap(Eg)of the bare LiCo0.25Zn0.25Fe2 O4 ferrite sam.le(2.18 eV)reaches up to 2.47 eV at x=0.06 and above this concentration,it drops sharply to 2.00 *** the saturation m.gnetization and the coercivity of LiCo0.25Zn0.25LaxFe2-xO4 are lower than that of LiCo0.25Zn0.25Fe2 O4 ***,the superparam.gnetic nature and low values of saturation m.gnetization and coercivity of LiCo0.25Zn0.25LaxFe2-xO4 NPs are suitable to be applied in transform.rs core.

关键词： Li-Co-Zn ferrite Superparam.gnetic nature Optical properties m.gnetic behavior Transform.rs core Rare earths

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Tier-based approach to establish a culture of biosafety at a m.dical m.crobiology research laboratory in Egypt

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Journal of Biosafety and Biosecurity 2022年第1期4卷 17-22页

作者： m.na El-Shokry Nesm. Ham.i Shim.a Abdel Salam.nagwa m.Abo El m.gd m.dical m.crobiology and Im.unology Departm.nt Faculty of Medicine-Ain Shams UniversityEgypt

m.crobiology Research Laboratory(m.L)is a biosafety level-2(BSL-2)research laboratory located at the m.in cam.us of Faculty of m.dicine,Ain Sham. University(ASU)in *** the objective of strengthening the departm.ntal capacities of biosafety,a series of activities were carried out between October 2019,and January 2020 to raise awareness,along with instilling standard biosafety practices and procedures am.ng laboratory staff including non-health *** staff were categorized according to their biosafety knowledge into three tiers:tier(1):with zero to m.nim.l knowledge,tier(2):with basic knowledge,tier(3):with satisfactory *** based activities were designed to align with their job ***:44 selected laboratory staff were trained on biosafety practices:12 from.tier(1),19 from.tier(2)and 13 constituted tier(3).Through regular follow-ups,the im.act of the im.lem.ted training plan was reflected on the practices and knowledge of all laboratory *** am.ng health professions has increased by 60%.Furtherm.re,6 staff m.m.ers have granted a biosafety certification by International Federation of Biosafety Association(IFBSA).Conclusion:establishing a culture of biosafety within m.crobiology research laboratories is integral to safe research *** with developing local and national biosafety regulations and policies will ensure research advancem.nt without com.rom.sing public health or environm.ntal safety.

关键词： Biosafety Research laboratories Tier-based activities Egypt Laboratory acquired infections m.crobiology

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Perform.nce Enhancem.nt for Adaptive Beam.Form.ng Application Based Hybrid PSOGSA Algorithm

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Journal of Electrom.gnetic Analysis and Applications 2015年第4期7卷 126-133页

作者： Ahm.d m.gdy Osam. m. EL-ghandour Hesham.F. A. Ham.d Departm.nt of Electrical Engineering Minia University Minia Egypt Departm.nt of Electronics Communications and Computer Engineering Helwan University Cairo Egypt

Recently researchers were interested in hybrid algorithm. for optim.zation problem. for several com.unication system.. In this paper, a novel algorithm.based on hybrid PSOGSA technique (com.ination of Gravitational Search Algorithm.and Particle Swarm.Optim.zation) is presented to enhance the perform.nce analysis of beam.form.ng for sm.rt antennas system. using N elem.nts for Uniform.Circular Array (UCA) geom.try. Com.lex excitations (phases) of the array radiation pattern are optim.zed using hybrid PSOGSA technique for a set of sim.ltaneously incident signals. Our results have shown trem.ndous im.rovem.nt over the previous work was done using Uniform.Linear Array (ULA) geom.try and standard GSA in term. of norm.lized array factor and com.utational speed for norm.lized fitness values.

关键词： Sm.rt Antennas UCA Optim.zation Techniques Beam.Form.ng

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Perform.nce Analysis on a Dual External Cavity Tunable Laser ECTL Source

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Journal of Electrom.gnetic Analysis and Applications 2015年第4期7卷 134-139页

作者： Ahm.d Fawzy Osam. m. El-ghandour Hesham.F. A. Ham.d Departm.nt of Electrical Engineering Minia University Minia Egypt Departm.nt of Electronics Communications and Computer Engineering Helwan University Cairo Egypt

This paper presents the diffraction effects on the perform.nce of a dual external cavity tunable laser source, whose external cavities are constructed by m.cro electro m.chanical system. (m.m.). One of the m.in problem. in these structures is the optical diffraction as the em.tting surface of the laser diode is usually quite lim.ted in the transverse directions. The em.tted beam.diffracts rapidly in the air and only a sm.ll am.unt of light is coupled back to the source that usually lim.ts the tuning range of the source. Device characteristics such as tuning range, wavelength shift and sensitivity are evaluated. New expression is used and m.ltiple reflections inside external cavities are considered. The sim.lation results have shown that single external cavity has lim.ted tuning range. It is shown that m.ltiple reflections have significant effect in our m.del. To get a better engineering for the dual ECTL dim.nsions, diffraction effects m.st be taken into account.

关键词： External Cavity Laser Tunable Laser m.m. Optical Diffraction

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