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Incidental Diagnosis of a Brown Tumor Mimicking Bone and Lung Metastasis during a Parathyroid Scintigraphy

Advances in Molecular Imaging 2020年第2期10卷 7-13页

作者： Fabrice Fokoué Sanae El Mselmi nadia Abaouz nadia ismaili Alaoui Nuclear Medicine Department Oncology Hospital Teaching Hospital Hassan II Faculty of Medicine and Pharmacy Sidi Mohamed Ben Abdellah University Fez Morocco

We report herein a case of a 40-year-old male patient with chronic renal failure presenting a severe hyperparathyroidism with an elevation of parathormone level evaluated in nuclear medicine department for MIBI-Technetium-99m parathyroid scintigraphy. The parathyroid scintigraphy revealed the appearance of a preferential fixation of the MIBI-99mTc opposite the lower left pole of the thyroid and opposite the upper part of the right hemi thorax. A subsequent single-photon emission computed tomography-computed tomography focused on the cervico-thoracic region was performed and showed an ectopic parathyroid adenoma associated with an incidental brown tumor mimicking bone and lung metastases. Our case report confirms the usefulness of additional hybrid SPECT-CT imaging in the management of hyperparathyroidism.

关键词： Hyperparathyroidism Thyroid Scintigraphy Parathyroid Scintigraphy Technetium-99m MIBI-Technetium-99m SPECT/CT Ectopic Parathyroid Adenoma Brown Tumor

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Papillary Thyroid Carcinoma and Pregnancy: What Impact on Prognosis?

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Case Reports in Clinical Medicine 2023年第1期12卷 22-29页

作者： Loubna Saadaoui Fatima Zahra Lahmamssi Hayat Aynaou Houda Salhi nadia Alaoui ismaili Hanan El Ouahabi Department of Endocrinology Diabetology and Nutrition Hassan II University Hospital Fez Morocco Faculty of Medicine and Pharmacy of Fez Sidi Mohamed Ben Abdullah University Fez Morocco Laboratory of Epidemiology and Research in Health Sciences Fez Morocco Nuclear Medicine Department Hassan II University Hospital Fez Morocco

Introduction: The impact of pregnancy on the prognosis of papillary thyroid carcinoma (PTC) has been debated for several decades;however, no definitive conclusions have been reached. The main objective of this study is to demonstrate the short-term influence of pregnancy on the evolution and prognosis of PTC. Materials and Methods: A prospective descriptive and analytical study was conducted in the Endocrinology and Diabetology Department at the Hassan II University Hospital in Fez, including patients followed for papillary thyroid carcinoma presenting with a pregnancy during the year 2019 and 2020. The follow-up of these patients was continued until 1 year postpartum. We studied the clinical, paraclinical and therapeutic factors that could influence the prognosis of the disease. Results: We included 26 patients. Our study showed a significant correlation between recurrence and the presence of unfavorable histological signs (p = 0.02) as well as the initial Tg level (0.01). However, pregnancy was not an influencing factor (p = 0.41). Conclusion: Pregnancy does not seem to be a factor aggravating the prognosis of differentiated thyroid cancers.

关键词： Papillary Thyroid Carcinoma Well Differentiated Pregnancy Recurrence Prognostic Factors

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Epidemiology of Pemphigus: A Single Center Experience in Morocco

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International Journal of Dermatology and Venereology 2022年第1期5卷 20-26页

作者： Farah El Hadadi Line Mezni Karima Senouci Laila Benzekri nadia ismaili Mariame Meziane Department of Dermatology-Venereology Ibn Sina University HospitalMohammed V UniversityRabat 10100Morocco

Objective:Pemphigus is a life threatening autoimmune bullous disease which involves the skin and mucous membranes of the stratified squamous *** global distribution of Pemphigus varies according to genetic,ethnic,socioeconomic,and cultural *** purpose of our study is to evaluate the epidemiological features of pemphigus a single center in Morocco and compare our results with those reported ***:A retrospective analysis was conducted of 302 pemphigus patients seen between 1990 and 2020 in the Dermatology Department of Ibn Sina Hospital(Rabat,Morocco).We further collected all the Moroccan scientific researches published by now to ***:The average annual incidence was 0.32/100,000 *** incidence doubled to 0.72 in *** most common variant was pemphigus vulgaris(125 cases)followed by pemphigus erythematosus(99 cases),pemphigus foliaceous(40 cases),and vegetans(27 cases).The female to male ratio was 0.75,the average age at onset was 53 years old and the mean duration of the disease before diagnosis was ***:This study joins the main characteristics of pemphigus in the Maghreb and around the world(pemphigus vulgaris most frequent subtype).In 2020,an epidemiological peak occurred during the coronavirus disease 2019 pandemic;probably related to stress and delayed time consultation for fear of contracting the severe acute respiratory syndrome coronavirus 2.

关键词： pemphigus epidemiology Rabat Morocco autoimmune bullous disease desmoglein

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