Papillary Thyroid Carcinoma and Pregnancy: What Impact on Prognosis?
Papillary Thyroid Carcinoma and Pregnancy: What Impact on Prognosis?作者机构:Department of Endocrinology Diabetology and Nutrition Hassan II University Hospital Fez Morocco Faculty of Medicine and Pharmacy of Fez Sidi Mohamed Ben Abdullah University Fez Morocco Laboratory of Epidemiology and Research in Health Sciences Fez Morocco Nuclear Medicine Department Hassan II University Hospital Fez Morocco
出 版 物:《Case Reports in Clinical Medicine》 (临床医学病理报告(英文))
年 卷 期:2023年第12卷第1期
页 面:22-29页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:Papillary Thyroid Carcinoma Well Differentiated Pregnancy Recurrence Prognostic Factors
摘 要:Introduction: The impact of pregnancy on the prognosis of papillary thyroid carcinoma (PTC) has been debated for several decades;however, no definitive conclusions have been reached. The main objective of this study is to demonstrate the short-term influence of pregnancy on the evolution and prognosis of PTC. Materials and Methods: A prospective descriptive and analytical study was conducted in the Endocrinology and Diabetology Department at the Hassan II University Hospital in Fez, including patients followed for papillary thyroid carcinoma presenting with a pregnancy during the year 2019 and 2020. The follow-up of these patients was continued until 1 year postpartum. We studied the clinical, paraclinical and therapeutic factors that could influence the prognosis of the disease. Results: We included 26 patients. Our study showed a significant correlation between recurrence and the presence of unfavorable histological signs (p = 0.02) as well as the initial Tg level (0.01). However, pregnancy was not an influencing factor (p = 0.41). Conclusion: Pregnancy does not seem to be a factor aggravating the prognosis of differentiated thyroid cancers.