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Prostate sclerosing adenopathy:A clinicopathological and immunohistochemical study of twelve patients

World Journal of Clinical Cases 2022年第18期10卷 6009-6020页

作者： run-Lin Feng Yan-ping Tao Zhi-Yong Tan Shi Fu Hai-Feng Wang Department of Pathology The Second Affiliated Hospital of Kunming Medical UniversityKunming 650101Yunnan ProvinceChina Department of Emergency Kunming Third People's HospitalKunming 650000Yunnan ProvinceChina Department of Urology The Second Affiliated Hospital of Kunming Medical UniversityKunming 650101Yunnan ProvinceChina

BACKGROUND Although sclerosing adenopathy of the prostate is a very rare benign disease,an effective differential diagnosis is ***,we report the clinicopathological and immunohistochemical morphological features of 12 cases of sclerosing adenopathy of the prostate to improve understanding of the *** To investigate the clinicopathological features,diagnosis,and immunohistochemical phenotypes that distinguish prostate sclerosing adenopathy from other *** The clinical data,laboratory tests,pathological morphology,and immunohistochemical phenotypes of 12 cases of prostatic sclerosing adenopathy were retrospectively analyzed,and the relevant literature was *** All patients were elderly men(mean age,71.7 years;62–83 years).Eleven of them had hematuria,urinary frequency,urinary urgency,difficulty in urination,and serum total prostate-specific antigen values within the normal *** patient had increased blood *** prostates with single to multiple calcifying foci were ***,prostate tissue hyperplastic changes were observed in all *** follicular hyperplastic nodules without an obvious envelope,with a growth pattern mimicking the infiltration pattern of"prostate adenocarcinoma"were *** cells expressed AR,CKH,P63,and CK5/6,and myoepithelial markers,such as calponin,S100,and smooth muscle *** recurrence or exacerbation of the lesions was observed,except for one case of death due to bladder *** Prostatic sclerosing adenopathy is highly misdiagnosed as prostate adenocarcinoma or other tumor-like ***,it should attract the attention of clinicopathologic researchers.

关键词： Clinicopathology Immunohistochemistry Prostate disease Sclerosing adenopathy

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Predictors and optimal management of tumor necrosis factor antagonist nonresponse in inflammatory bowel disease:A literature review

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World Journal of Gastroenterology 2023年第29期29卷 4481-4498页

作者： Liang-Fang Wang ping-run Chen Si-Ke He Shi-Hao Duan Yan Zhang Department of Gastroenterology and Hepatology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina West China School of Medicine Sichuan UniversityChengdu 610041Sichuan ProvinceChina

Tumor necrosis factor-α(TNF-α)antagonists,the first biologics approved for treating patients with inflammatory bowel disease(IBD),are effective for the induction and maintenance of remission and significantly improving ***,up to one-third of treated patients show primary nonresponse(PNR)to anti-TNF-αtherapies,and 23%-50%of IBD patients experience loss of response(LOR)to these biologics during subsequent *** is still no recognized predictor for evaluating the efficacy of anti-TNF *** review summarizes the existing predictors of PNR and LOR to anti-TNF in IBD *** predictors remain controversial,and only previous surgical history,disease manifestations,drug concentrations,antidrug antibodies,serum albumin,some biologic markers,and some genetic markers may be potentially *** addition,we also discuss the next steps of treatment for patients with PNR or LOR to TNF *** drug monitoring plays an important role in treatment *** escalation,combination therapy,switching to a different anti-TNF drug,or switching to a biologic with a different mechanism of action can be selected based on the concentration of the drug and/or antidrug antibodies.

关键词： Predictor Management Tumor necrosis factor antagonist Primary nonresponse Secondary nonresponse Inflammatory bowel disease

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The novel coronavirus outbreak in Wuhan,China

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Global Health Research and Policy 2020年第1期5卷 377-379页

作者： Hengbo Zhu Li Wei ping niu Department of Pediatric Renmin Hospital of Wuhan universityWuhan 430060China

The novel coronavirus(2019-nCoV,or COVID-19)epidemic first broke out in Wuhan and has been spreading in whole China and the *** numbers of new infections and deaths in Wuhan are still increasing,which have posed major public health and governance concerns.A series of mandatory actions have been taken by the municipal and provincial governments supported by the central government,such as measures to restrict travels across cities,case detection and contact tracing,quarantine,guidance and information to the public,detection kit development,*** such as lacking effective drugs,insufficient hospital services and medical supplies,logistics,*** much alleviated with the solidarity of the whole *** pandemic will definitely be ended with the continuous efforts of both national and international multi-sectoral bodies.

关键词： Novel coronavirus 2019-nCoV COVID-19 Pneumonia Outbreak Wuhan Global health

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Synthesis, Character and Crystal Structure of the Complex {Er(DMSO)_7}PW_(12)O_(40)

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Chinese Journal of Structural Chemistry 2007年第8期26卷 949-954页

作者： HAN Qiu-Xi ZHANG Da-Li MA Jian-Ru WANG Jing-ping niu Jing-Yang Institute of Molecular and Crystal Engineering Basic Experiment Teaching Center Henan University Kaifeng 475001 China School of Environment and.Planning Henan University Kaifeng 475001 China School of Chemistry and Chemical Engineering Henan University Kaifeng 475001 China

The synthesis, X-ray crystal structure, thermal properties and electrochemistry of the new complex formulated as {Er（DMSO）7}PW12O40 are reported. The single-crystal X-ray analysis reveals that the crystal crystallizes in the monoclinic system, space group P21/c with a=11.767（2）, b=14.909（3）, c=34.905（7）A, β=98.97（3）°, Mr=3591.33, V=6049（2）A^3, Dc=3.944g/cm^3, Z=4, GOOF=1.098, F（000）=6340, R=0.0490 and wR=0.1202. Crystal structure analysis indicates that the Er（Ⅲ） is seven-coordinate with a distorted pentagonal bipyramid and combines to the anion [PW12O40]3- via static electric force.

关键词： heteropolyanion erbium complex crystal structure

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Digital simulation of 3D turbulence wind field of Sutong Bridge based on measured wind spectra

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2012年第2期13卷 91-104页

作者： Hao WANG Zhou-hong ZONG Ai-qun LI Teng TONG Jie niu Wen-ping DENG Key Laboratory of Concrete and Prestressed Concrete Structures of Ministry of Education Southeast UniversityNanjing 210096China Key Laboratory of Environmental Impact and Structural Safety in Engineering China University of Mining&TechnologyXuzhou 221116China

Time domain analysis is an essential implement to study the buffeting behavior of long-span bridges for it can consider the non-linear effect which is significant in long-span bridges. The prerequisite of time domain analysis is the accurate description of 3D turbulence winds. In this paper, some hypotheses for simplifying the 3D turbulence simulation of long-span cable-stayed bridges are conducted, considering the structural characteristics. The turbulence wind which is a 3D multivariate stochastic vector process is converted into four independent 1D univariate stochastic processes. Based on recorded wind data from structural health monitoring system (SHMS) of the Sutong Bridge, China, the measured spectra expressions are then presented using the nonlinear least-squares fitting method. Turbulence winds at the Sutong Bridge site are simulated based on the spectral representation method and the Fast Fourier transform (FFT) technique, and the relevant results derived from target spectra including measured spectra and recommended spectra are compared. The reliability and accuracy of the presented turbulence simulation method are validated through comparisons between simulated and target spectra (measured and recommended spectra). The obtained turbulence si-mulations can not only serve further analysis of the buffeting behavior of the Sutong Bridge, but references for structural anti-wind design in adjacent regions.

关键词： Turbulence simulation Spectral representation method Fast Fourier transform (FFT) Cable-stayed bridges Struc-tural health monitoring system (SHMS) Power spectral density

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Nanoparticle-immersed paper imprinting mass spectrometry imaging reveals uptake and translocation mechanism of pesticides in plants

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Nano Research 2020年第3期13卷 611-620页

作者： Xinzhou Wu run Qin Hanxiang Wu Guangkai Yao Yue Zhang ping Li Yizhu Xu Zhixiang Zhang Zhibin Yin Hanhong Xu State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources South China Agricultural UniversityGuangzhou510642China Key Laboratory of Natural Pesticide and Chemical Biology of the Ministry of Education South China Agricultural UniversityGuangzhou510642China School of Pharmaceutical Sciences Sun Yat-sen UniversityGuangzhou510006China

Design and discovery of carrier-mediated modified pesticides are vital for reducing pesticide dosage and increasing utilization,yet it remains a great challenge due to limited insights into plant translocation ***/nanoparticle assisted laser desorption/ionization strategy has established itself as a preferential analytical tool for biological tissue analysis,whereas potential applications in plant sciences are hindered with regard to the inability to slice plant leaves and ***,we report gold nanoparticle(AuNP)-immersed paper imprinting mass spectrometry imaging(MSI)for the spatiotemporal visualization of pesticide translocation in plant *** approach plays a dual role in preserving spatial information and improving ionization efficiency for pesticides regardless of imaging artifacts due to homogenous AuNP *** this MSI platform,we proposed the elaborate plant translocation mechanism of agrochemicals for the first time,which is currently poorly *** dynamic processes of carrier-mediated pesticides can be clearly visualized,including crossing of plasma membranes by transporters,translocation downward in stems through the phloem,diffusion to the xylem and,conversely,accumulation at margins of the treated ***,this AuNP-assisted paper imprinting method could be highly compatible with laser-based MSI instruments,expediting researches across a broad range of fields,especially in nanomaterial development and life sciences.

关键词： gold nanoparticles nanoparticle-immersed paper imprinting mass spectrometry imaging plant translocation mechanism carrier-mediated pesticides

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Helmholtz decomposition with a scalar Poisson equation in elastic anisotropic media

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Petroleum Science 2024年第3期21卷 1597-1610页

作者： Xin-Yu Fang Gang Yao Qing-Qing Zheng ping-Min Zhang Di Wu Feng-Lin niu State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China Unconventional Petroleum Research Institute China University of Petroleum(Beijing)Beijing102249China Department of Mathematics College of ScienceChina University of Petroleum(Beijing)Beijing102249China College of Geophysics China University of Petroleum(Beijing)Beijing102249China Department of Earth Environmental and Planetary SciencesRice UniversityHoustonTX77005UA

P-and S-wave separation plays an important role in elastic reverse-time *** can reduce the artifacts caused by crosstalk between different modes and improve image *** addition,P-and Swave separation can also be used to better understand and distinguish wave types in complex *** present,the methods for separating wave modes in anisotropic media mainly include spatial nonstationary filtering,low-rank approximation,and vector Poisson *** of these methods require multiple Fourier transforms or the calculation of large matrices,which require high computational costs for problems with large *** this paper,an efficient method is proposed to separate the wave mode for anisotropic media by using a scalar anisotropic Poisson operator in the spatial *** 2D problems,the computational complexity required by this method is 1/2 of the methods based on solving a vector Poisson ***,compared with existing methods based on pseudoHelmholtz decomposition operators,this method can significantly reduce the computational *** examples also show that the P and S waves decomposed by this method not only have the correct amplitude and phase relative to the input wavefield but also can reduce the computational complexity significantly.

关键词： Anisotropic media Scalar anisotropic Poisson equation Improved elastic wavefield decomposition

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Strong interface contact between NaYF_(4):Yb,Er and CdS promoting photocatalytic hydrogen evolution of NaYF_(4):Yb,Er/CdS composites

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Journal of Materials Science & Technology 2022年第7期102卷 1-1,2-7页

作者： Huaze Zhu Yongqiang Yang Yuyang Kang ping niu Xiangdong Kang Zhiqing Yang Hengqiang Ye Gang Liu Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China School of Metallurgy Northeastern UniversityShenyang 110819China Jihua Laboratory Foshan 528000China

To acquire efficient photocatalysts,it is necessary to make effective use of visible light/Near Infrared(NIR)light,which takes up a large percentage of *** upconversion materials with visible light active photocatalysts has attracted much attention in this *** interface contact between upcon-version material and photocatalyst has potential influence on the properties and thus the performance of the *** this work,NaYF_(4):Yb,Er/CdS composites of the upconversion material NaYF_(4):Yb,Er nanorods and CdS nanoparticles were synthesized by ion adsorption/precipitation process and were then annealed in an argon atmosphere at different temperatures to modulate the *** annealing pro-cess endows the crystal transformation of cubic CdS with low crystallinity to hexagonal CdS with high crystallinity and,importantly,good interface contact between NaYF_(4):Yb,Er and ***,the hy-drogen evolution activity greatly increases from 171 to 2539μmol h^(−1) g^(−1) under the light irradiation ofλ>400 nm,and from 0 to 19μmol h^(−1) g^(−1) under the light irradiation ofλ>600 *** work might provide a useful reference for the rational design of promising photocatalyst involving upconversion ma-terials.

关键词： NaYF_(4):Yb Er CdS Upconversion Photocatalytic Composite

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Research on the fracture behavior of PBX under static tension

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Defence Technology（防务技术） 2014年第2期10卷 154-160页

作者： Hu GUO Jing-run LUO ping-an SHI Jian-guo XU Institute of Systems Engineering China Academy of Engineering Physics

The fracture behavior of polymer-bonded explosive(PBX) seriously affects the safety and reliability of weapon *** effects of interface debonding and initial meso-damage on the fracture behavior of PBX under quasi-static tension are studied using numerical method.A twodimensional representative volume element(RVE) is established based on Voronoi model in which the component contents could be regulated and the particles are randomly distributed.A nonlinear damage model of polymer matrix relative to matrix depth between particles is *** results show that the simulated strain-stress relation is coincident with experiment *** is found that interface debonding leads to the nucleation and propagation of meso-cracks,and a main crack approximately perpendicular to the loading direction is generated *** interface debonding tends to occur in the interface perpendicular to the loading *** seems to be a phenomenon that strain softening and hardening alternatively appear around peak stress of stress and strain *** is shown that the initial damages of intragranular and interfacial cracks both decrease the modulus and failure stress,and the main crack tends to propagate toward the initial meso-cracks.

关键词：拉伸断裂行为 PBX 准静态界面裂纹损伤模型峰值应力裂纹传播武器系统

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One-step wet-spinning assembly of twisting-structured graphene/carbon nanotube fiber supercapacitor

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Journal of Energy Chemistry 2020年第12期29卷 434-441页

作者： Zhengpeng Yang Yuanheng Jia Yutao niu Yongyi Zhang Chunjing Zhang ping Li Meng Zhu Qingwen Li Henan Key Laboratory of Materials on Deep-Earth Engineering School of Materials Science and EngineeringHenan Polytechnic UniversityJiaozuo 454003HenanChina Key Laboratory of Multifunctional Nanomaterials and Smart Systems Advanced Materials DivisionSuzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123JiangsuChina School of Nano-Tech and Nano-Bionics University of Science and Technology of ChinaHefei 230026AnhuiChina Division of Nanomaterials and Jiangxi Key Lab of Carbonene Materials Suzhou Institute of Nano-Tech and Nano-BionicsNanchangChinese Academy of SciencesNanchang 330200JiangxiChina

Graphene fiber-based supercapacitors hold great promise as flexible energy-storage devices. However, simultaneously achieving high ion-transport ability in electrode and electrolyte layer, which is crucial for realizing the high electrochemical performance, still remains challenging. Here, a facile and effective strategy to solve the problem was proposed by developing a twisting-structured graphene/carbon nanotube(CNT) fiber supercapacitor via one-step wet-spinning process with customized multi-channel *** remarkable structure features of the resulting fiber supercapacitor with wrinkled and thin electrolyte layer, and well-developed porosity of fiber electrode favored the rapid infiltration and transport of electrolyte ions inside the electrode, as well as between electrode and electrolyte, thus boosting high specific capacitance of 187.6 mF cm^(-2) and energy density of 30.2 μWh cm^(-2), and featuring long cycling life(93%capacitance retention after 10,000 cycles) and excellent flexibility. Moreover, the specific capacitance and energy density could be further improved to 267.2 m F cm^(-2) and 66.8 μWh cm^(-2), respectively, when Mn O2 was incorporated into the fiber.

关键词： One-step wet-spinning Graphene fiber-based supercapacitor Twisting-structured fiber Ion transport

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