Nanoparticle-immersed paper imprinting mass spectrometry imaging reveals uptake and translocation mechanism of pesticides in plants

作     者：Xinzhou Wu Run Qin Hanxiang Wu Guangkai Yao Yue Zhang Ping Li Yizhu Xu Zhixiang Zhang Zhibin Yin Hanhong Xu Xinzhou Wu;Run Qin;Hanxiang Wu;Guangkai Yao;Yue Zhang;Ping Li;Yizhu Xu;Zhixiang Zhang;Zhibin Yin;Hanhong Xu

作者机构：State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresourcesSouth China Agricultural UniversityGuangzhou510642China Key Laboratory of Natural Pesticide and Chemical Biology of the Ministry of EducationSouth China Agricultural UniversityGuangzhou510642China School of Pharmaceutical SciencesSun Yat-sen UniversityGuangzhou510006China 

出 版 物：《Nano Research》 (纳米研究（英文版）)

年 卷 期：2020年第13卷第3期

页      面：611-620页

核心收录：

学科分类：090403[农学-农药学(可授农学、理学学位）] 09[农学] 0904[农学-植物保护] 

基　　金：support from the National Natural Science Foundation of China(Nos.31901911 and 21904142) the National Key R&D Program of China(No.2018YFD0200300) the Natural Science Foundation of Guangdong Province(No.2018A030310215) This work is also supported by the project funded by the National Postdoctoral Program for Innovative Talents(No.BX20180399) 

主　　题：gold nanoparticles nanoparticle-immersed paper imprinting mass spectrometry imaging plant translocation mechanism carrier-mediated pesticides 

摘      要：Design and discovery of carrier-mediated modified pesticides are vital for reducing pesticide dosage and increasing utilization,yet it remains a great challenge due to limited insights into plant translocation ***/nanoparticle assisted laser desorption/ionization strategy has established itself as a preferential analytical tool for biological tissue analysis,whereas potential applications in plant sciences are hindered with regard to the inability to slice plant leaves and ***,we report gold nanoparticle(AuNP)-immersed paper imprinting mass spectrometry imaging(MSI)for the spatiotemporal visualization of pesticide translocation in plant *** approach plays a dual role in preserving spatial information and improving ionization efficiency for pesticides regardless of imaging artifacts due to homogenous AuNP *** this MSI platform,we proposed the elaborate plant translocation mechanism of agrochemicals for the first time,which is currently poorly *** dynamic processes of carrier-mediated pesticides can be clearly visualized,including crossing of plasma membranes by transporters,translocation downward in stems through the phloem,diffusion to the xylem and,conversely,accumulation at margins of the treated ***,this AuNP-assisted paper imprinting method could be highly compatible with laser-based MSI instruments,expediting researches across a broad range of fields,especially in nanomaterial development and life sciences.