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Development of an experimental method for well-controlled blast induced traumatic limb fracture in rats

Defence Technology（防务技术） 2024年第4期34卷 168-176页

作者： Luyang Xu Xiancheng Yu Clement DFavier Ibidumo Igah Thuy-Tien nguyen Warren Macdonald Anthony MJ.Bull Centre for Blast Injury Studies Imperial College LondonLondonUnited Kingdom Department of Bioengineering Imperial College LondonLondonUnited Kingdom Dyson School of Design Engineering Imperial College LondonLondonUnited Kingdom Department of Trauma and Orthopaedics Royal Free London National Health Service Foundation TrustLondonUnited Kingdom

Heterotopic ossification(HO)is a consequence of traumatic bone and tissue damage,which occurs in 65%of military casualties with blast-associated ***,the mechanisms behind blast-induced HO remain *** models are used to study blast-induced HO,but developing such models is challenging,particularly in how to use a pure blast wave(primary blast)to induce limb fracture that then requires an *** studies,including our recent study,have developed platforms to induce limb fractures in rats with blast loading or a mixture of blast and impact ***,these models are limited by the survivability of the animal and repeatability of the *** this study,we developed an improved platform,aiming to improve the animal's survivability and injury repeatability as well as focusing on primary blast *** platform exposed only one limb of the rat to a blast wave while providing proper protection to the rest of the rat's *** obtained very consistent fracture outcome in the tibia(location and pattern)in cadaveric rats with a large range of size and ***,the rats did not obviously move during the test,where movement is a potential cause of uncontrolled *** further conducted parametric studies by varying the features of the design of the *** factors,such as how the limb is fixed and how the cavity through which the limb is placed is sealed,significantly affect the resulting *** platform and test setups enable well-controlled limb fracture induced directly by pure blast wave,which is the fundamental step towards a complete in vivo animal model for blast-induced HO induced by primary blast alone,excluding secondary and tertiary blast *** addition,the platform design and the findings presented here,particularly regarding the proper protection of the animal,have implications for future studies investigating localized blast injuries,such as blast induced brain and lung injuries.

关键词： Blast injury Biomechanics Heterotopic ossification Limb fracture Blast wave Animal model

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Cellular models of stress resistance may pave ways to fight neurodegenerative diseases

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Neural Regeneration Research 2025年第9期20卷 2579-2580页

作者： Thu nguyen Minh Pham Christian Behl Institute of Pathobiochemistry University Medical Center of the Johannes Gutenberg UniversityMainzGermany

Alzheimer's disease(AD),the most common form of neurodegeneration,is characterized by selective neuronal vulnerability and brain regionselective neuron *** entorhinal cortex and hippoc,ampal CA1 projection neurons are at greater risk in AD whereas other regions display resistance to ***,the cerebellum,a phylogenetically very old region,is affected only very late in the disease progression.

关键词： cortex resistance Alzheimer

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Optimal Scheduling of Multiple Rail Cranes in Rail Stations with Interference Crane Areas

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Intelligent Automation & Soft Computing 2024年第1期39卷 15-31页

作者： nguyen Vu Anh Duy nguyen Le Thai nguyen Huu Tho Faculty of Engineering and Technology Nguyen Tat Thanh UniversityHo Chi Minh City700000Vietnam

In this paper,we consider a multi-crane scheduling problem in rail stations because their operations directly influence the throughput of the rail *** particular,the job is not only assigned to cranes but also the job sequencing is implemented for each crane to minimize the makespan of cranes.A dual cycle of cranes is used to minimize the number of working cycles of *** rail crane scheduling problems in this study are based on the movement of *** consider not only the gantry moves,but also the trolley moves as well as the rehandle cases are also included.A mathematical model of multi-crane scheduling is *** traditional and parallel simulated annealing(SA)are adapted to determine the optimal scheduling *** examples are conducted to evaluate the applicability of the proposed *** of the proposed parallel SA is done by comparing it to existing previous *** of numerical computation highlighted that the parallel SA algorithm outperformed the SA and gave better solutions than other considered algorithms.

关键词： Multi-crane scheduling logistics containers makespan rail stations

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Machine learning based models for predicting compressive strength of geopolymer concrete

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 1028-1049页

作者： Quang-Huy LE Duy-Hung nguyen Thanh SANG-TO Samir KHATIR Hoang LE-MINH Amir H.GANDOMI Thanh CUONG-LE Center for Engineering Application and Technology Solutions Ho Chi Minh City Open UniversityHo Chi Minh 700000Vietnam Institute of Civil Engineering Ho Chi Minh City University of TransportHo Chi Minh 700000Vietnam Faculty of Engineering&Information Technology University of Technology SydneyUltimoNSW 2007Australia

Recently,great attention has been paid to geopolymer concrete due to its advantageous mechanical and environmentally friendly *** effort has been made in experimental studies to advance the understanding of geopolymer concrete,in which compressive strength is one of the most important *** facilitate engineering work on the material,an efficient predicting model is *** this study,three machine learning(ML)-based models,namely deep neural network(DNN),K-nearest neighbors(KNN),and support vector machines(SVM),are developed for forecasting the compressive strength of the geopolymer concrete.A total of 375 experimental samples are collected from the literature to build a database for the development of the predicting models.A careful procedure for data preprocessing is implemented,by which outliers are examined and removed from the database and input variables are standardized before feeding to the fitting *** standard K-fold cross-validation approach is applied for evaluating the performance of the models so that overfitting status is well managed,thus the generalizability of the models is *** effectiveness of the models is assessed via statistical metrics including root mean squared error(RMSE),mean absolute error(MAE),correlation coefficient(R),and the recently proposed performance index(PI).The basic mean square error(MSE)is used as the loss function to be minimized during the model fitting *** three ML-based models are successfully developed for estimating the compressive strength,for which good correlations between the predicted and the true values are obtained for DNN,KNN,and *** numerical results suggest that the DNN model generally outperforms the other two models.

关键词： geopolymer concrete compressive strength prediction machine-learning based model deep neural network K-nearest neighbor support vector machines

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Fabricating ultralight and ultrathin copper current collectors for high-energy batteries

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eScience 2024年第5期4卷 143-149页

作者： Junxiang Liu Huanhuan Jia Dang nguyen Jingjing Liu Chengcheng Fang Department of Chemical Engineering and Materials Science Michigan State UniversityEast LansingMI 48824USA

Improving cell-level gravimetric and volumetric energy density is essential to achieve high-performance batteries in the rapidly evolving field of energy storage technology,which requires consideration of all cell *** current collectors(CCs)made of metal foil,especially the copper(Cu)current collector of the anode,possess high mass and cost yet do not contribute to *** the weight of Cu CC with minimum thickness and desirable mechanical strength is critical in enhancing energy density but is technically ***,we demonstrate a fast and scalable chemical coating method based on electroless plating for fabricating ultralight CC(∼1.72mgcm−2)with a thin Cu layer(500nm)on an ultrathin polyethylene(PE)polymer scaffold(5μm).The ultralight and ultrathin CC possesses high metal purity,high mechanical strength,high thermal stability,and outstanding electrochemical performances in lithium-ion and lithium-metal battery *** ultralight CC only exhibits∼30%of the weight of 6μm Cu foil,leading to a 5−10%improvement in cell-level gravimetric energy density without sacrificing volumetric energy ***,the simplicity and scalability of the chemical coating method make it a promising solution for the mass production of ultra-thin and lightweight current collectors.

关键词： Electroless plating Lithium-ion battery Ultralight current collectors Cell-level energy density Energy storage devices

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Visualizing the Spin & Radiation of the Extended Electron in Magnetic Field

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Journal of High Energy Physics, Gravitation and Cosmology 2024年第1期10卷 277-291页

作者： Hoa Van nguyen Retired Engineer and Amateur Researcher of Physics Toronto Canada

This article presents illustrations of an extended model of the electron to visualize how it spins and radiates in the external magnetic field. A time-varying magnetic field B produces a rotational induced electric field E which rotates (spins) the electron about its axis. In time-constant magnetic field: the electron radiates the cyclotron radiation. In time-varying magnetic field: synchrotron radiation is generated. The couplings between spin, acceleration and radiation will be discussed.

关键词： Spinning Forces Spin by Inertia Radiating Forces Photon or Static Electric Dipole Cloud of Photons Spin - Radiation Coupling

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Reviewing Stability Criteria for Positive Homogeneous Systems and Adding One for Discrete-Time Cases with Degree Less Than One

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Circuits and Systems 2024年第1期15卷 1-11页

作者： nguyen Quang Tuan Faculty of Information Technology Nha Trang University Khanh Hoa Vietnam

The article synthesizes and presents the results regarding the stability of positive homogeneous systems that have been researched and published in recent years. Next, we provide a sufficient condition for global exponential stability in the case of discrete-time positive homogeneous systems with an order less than one with time-varying delays.

关键词： Exponential Stability Homogeneous Systems Positive Systems Positive Homogeneous Systems

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Analysis of Traffic Accidents in Vietnam

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World Journal of Engineering and Technology 2024年第3期12卷 522-528页

作者： Thi Yen nguyen Faculty of Transport Safety and Environment University of Transport and Communications Ha Noi Vietnam

Understanding the causes and solutions of road traffic accidents is important for developing road and action plans in a country. In Vietnam, awareness of traffic participants is the main cause of serious traffic accidents. In recent years, the number of road traffic accidents in Tuyen Quang province with deaths has decreased, but the number of accidents has increased significantly. The article uses data on traffic accidents in Tuyen Quang over the (2016-2023) has been analytically reviewed. From there, analyze accident characteristics and causes of traffic accidents in Tuyen Quang province, and propose solutions to improve traffic safety in Tuyen Quang, Vietnam. The findings can be information for managers and researchers interested in studying the province of Tuyen Quang, Vietnam road traffic safety. Additionally, the findings have led the government to achieve national targets in reducing the number of accidents and serious injuries.

关键词： Traffic Safety Accident Cause Driver Behavior Human Factor Traffic Safety Policy

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One-loop contributions for h→ℓℓγ and e−e+→hγ in the U(1)_(B−L) extension of the standard model

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Chinese Physics C 2024年第5期48卷 23-49页

作者： Tran Dzung Tri Thanh Huy nguyen Khiem Hong Phan Institute of Fundamental and Applied Sciences Duy Tan UniversityHo Chi Minh City 700000Vietnam Faculty of Natural Sciences Duy Tan UniversityDa Nang City 550000Vietnam VNUHCM-University of Science 227 Nguyen Van CuDistrict 5Ho Chi Minh CityVietnam

We present one-loop contributions for h→ℓℓγ with ℓ=νe,μ,τ,e,μ and e−e+→hγ in the U(1)_(B−L) extension of the standard model. In the phenomenological results, the signal strengths for h→ℓℓγ at the Large Hadron Collider and for e−e+→hγ at future lepton colliders are analyzed in the physical parameter space for both the vector and chiral B−L models. We found that the contributions from the neutral gauge boson Z′ to the signal strengths are rather small. Consequently, the effects will be difficult to probe at future colliders. However, the impacts of charged Higgs and CP-odd Higgs in the chiral B−L model on the signal strengths are significant and can be measured with the help of the initial polarization beams at future lepton colliders.

关键词： Higgs phenomenology one-loop Feynman integrals analytic methods for quantum field theory dimensional regularization future lepton colliders

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Clinical Case Report of Acute Heart Injury and Acute Rhabdomyolysis Due to Cyanide Poisoning

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Open Journal of Emergency Medicine 2024年第2期12卷 29-32页

作者： nguyen Dang Duc nguyen Phuong Sinh Lam nguyen Hong Anh Poison Control Center of Bach Mai Hospital Hanoi Vietnam Thai nguyen Medicine and Pharmacy University Thai Nguyen Vietnam

Cyanide poisoning is one of the most dangerous poisonings, and it can be absorbed into the body through the mouth, inhalation and through the skin. A 32-year-old female patient was admitted to our poison control center because of high fever, severe vomiting, and seizures. Physical examination found that the patient was drowsy, had a high fever of 40 degrees Celsius, pulse of 140 beats/minute, and increased tendon and bone reflexes. Exploiting the patient’s information, it was discovered that the patient bought Cyanide to drink with the intention of committing suicide. The patient was quickly treated with gastric lavage and activated charcoal. Echocardiography recorded EF: 35%, reduced movement of the entire myocardium. CK blood test: 4562 U/L. The patient’s condition rapidly deteriorated and the patient was made ECMO, IHD and CVVHDF. After 3 days of treatment, the patient’s condition did not improve, so the family asked for the patient to go home. This article aims to describe the rapidly progressing and severe damage to the heart and muscles of patients with cyanide poisoning.

关键词： Cyanide Poisoning Acute Heart Injury Acute Rhabdomyolysis

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