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胡耀邦改革开放思想和实践的历史沉淀与定位——学习习近平同志在纪念胡耀邦百年诞辰会议上讲话的体会

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湖南科技大学学报（社会科学版） 2016年第2期19卷 49-51页

作者：胡应南北京大学国家软实力研究院北京100871

在胡耀邦诞辰100周年大会上,习近平总书记赞誉胡耀邦为中国改革开放的思想家和实干家,号召全党学习胡耀邦改革开放的思想精神以及对国家和人民的高度忠诚和负责精神。在当前新常态的历史时期,全党和全国人民应当继续发扬胡耀邦坚持改革... 详细信息

在胡耀邦诞辰100周年大会上,习近平总书记赞誉胡耀邦为中国改革开放的思想家和实干家,号召全党学习胡耀邦改革开放的思想精神以及对国家和人民的高度忠诚和负责精神。在当前新常态的历史时期,全党和全国人民应当继续发扬胡耀邦坚持改革开放、构建社会主义核心价值观和价值体系的那种高瞻远瞩、无私无畏、勇于担当的精神,继续学习和发扬胡耀邦廉洁奉公、全心全意为人民服务的共产主义精神。

关键词：胡耀邦改革开放思想家改革开放实干家

Fall preventive gait trajectory planning of a lower limb rehabilitation exoskeleton based on capture point theory

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Frontiers of Information Technology & Electronic Engineering 2019年第10期20卷 1322-1330页

作者： Mei-ying DENG Zhang-yi MA ying-nan WANG Han-song WANG Yi-bing ZHAO Qian-xiao WEI Wei YANG Can-jun YANG Zhejiang University Hospital Hangzhou 310027China State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang UniversityHangzhou 310027China

We study the balance problem caused by forward leaning of the wearer's upper body during rehabilitation training with a lower limb rehabilitation exoskeleton. The instantaneous capture point is obtained by modeling the human-exoskeleton system and using the capture point theory. By comparing the stability region with instantaneous capture points of different gait phases, the balancing characteristics of different gait phases and changes to the equilibrium state in the gait process are analyzed. Based on a model of the human-exoskeleton system and the condition of balance of different phases, a trajectory correction strategy is pro-posed for the instability of the human-exoskeleton system caused by forward leaning of the wearer's upper body. Finally, the reliability of the trajectory correction strategy is verified by carrying out experiments on the Zhejiang University Lower Extremity Exoskeleton. The proposed trajectory correction strategy can respond to forward leaning of the upper body in a timely manner. Additionally, in the process of the center of gravity transferred from a double-support phase to a single-support phase, the ratio of gait cycle to zero moment point transfer is reduced correspondingly, and the gait stability is improved.

关键词： Lower extremity exoskeleton Capture point Gait phase Balance of human-machine system

Comparison of Histological, Microbiological, and Molecular Methods in Diagnosis of Patients with TBLN Having Different Anti-TB Treatment Background

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Biomedical and Environmental Sciences 2017年第6期30卷 418-425页

作者： CHE nan ying HUANG Shao Jun MA Yan HAN Yi LIU Zi Chen ZHANG Chen MU Jing ZHAO Dan QU Yang ZHANG Hai Qing LIU Zhi Dong XU Shao Fa Department of Pathology Beijing Tuberculosis & Thoracic Tumor Research Institute Beijing Chest Hospital Capital Medical University Beijing 101149 China Department of Thoracic Surgery The affiliated hospital of Inner Mongolia Medical University Hohhot 010110 Inner Mongolia China Clinical Center Beijing Tuberculosis & Thoracic Tumor Research Institute Beijing Chest Hospital Capital Medical University Beo'ing 101149 China Department of Thoracic Surgery Beijing Tuberculosis & Thoracic Tumor Research Institute Beijing Chest Hospital Capital Medical University Beijing 101149 China

Objective The influence of anti-tuberculosis （TB） treatment history on tuberculous lymphadenitis （TBLN） diagnosis is unclear. Therefore, this study aims to evaluate the diagnostic methods, including histology, microbiology, and molecular tests, used for TBLN. Methods In this study, suspected patients with TBLN and having different anti-T8 treatment background were enrolled. All the samples were tested simultaneously by histology, ZiehI-Neelsen （ZN） staining, mycobacterial culture （culture）, Xpert MTB/RIF （xpert）, real-time PCR, and high-resolution melting curve PCR （HRM）. Thereafter, the performance of these methods on samples with different anti-TB treatment background was assessed. Results In our study, 89 patients were prospectively included 82 patients with TBLN and 7 with other diseases. The overall sensitivities of Xpert, real-time PCR, histology, ZN staining, and culture were 86.6%, 69.5%, 58.5%, 43.9%, and 22.0%, respectively. The anti-TB treatment history revealed dramatic influences on the sensitivity of culture （P 〈 0.0001）. In fact, the treatment that lasted over 3 months also influenced the sensitivity of Xpert （P 〈 0.05）. However, the treatment history did not affect the performance of remaining tests （P 〉 0.05）. For rifampicin drug susceptibility test （DST）, the anti-T8 treatment showed only significant influence on the success rate of culture DST （P = 0.001）, but not on those of Xpert and HRM tests （P 〉 0.05）. Conclusion Other tests as welt as culture should be considered for patients with TBLN having retreatment history or over 1-month treatment to avoid false negative results.

关键词： Tuberculous lymphadenitis Mycobacterial culture Molecular test Anti-TB treatment Drugresistance

Elevated peripheral blood neutrophil-to-lymphocyte ratio is associated with an immunosuppressive tumour microenvironment and decreased benefit of PD-1 antibody in advanced gastric cancer

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Gastroenterology Report 2021年第6期9卷 560-570页

作者： Dan-Yun Ruan Yan-Xing Chen Xiao-Li Wei ying-nan Wang Zi-Xian Wang Hao-Xiang Wu Rui-Hua Xu Shu-Qiang Yuan Feng-Hua Wang State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdongP.R.China Department of Medical Oncology the Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China Department of Medical Oncology Sun Yat-sen University Cancer CenterGuangzhouGuangdongP.R.China Department of Gastric Surgery Sun Yat-sen University Cancer CenterGuangzhouGuangdongP.R.China

Background Due to its limited efficacy and potential toxicity,anti-PD-1 monoclonal antibody is not suitable for all advanced gastric cancer(AGC)patients and predictive biomarkers identifying patients who can benefit from it are urgently *** study aimed to evaluate the predictive and prognostic value of inflammatory markers in the context of the systemic inflammatory status and tumour *** The study included 58 patients from a prospective study investigating the safety and efficacy of toripalimab in chemorefractory AGC *** characteristics,treatment outcomes,and haematological parameters were ***-cell infiltration and gene expression in tumour tissue were examined using transcriptome *** In this cohort,the median follow-up time was 4.5 months,the median progression-free survival was 1.9 months,and the median overall survival(OS)was 4.8 *** objective response rate was 12.1%and th disease control rate(DCR)was 39.7%.Both the baseline blood neutrophil-to-lymphocyte ratio(bNLR)with a cut-point of 2.7 and the early elevated dynamic change of the bNLR(dNLR)with a cut-point of 1.5 were prognostic factors of *** in the high bNLR or dNLR group had remarkably poor DCR(25.8%vs 59.1%,P=0.023;15.8%vs 54.6%,P=0.008).In multivariate analysis,bNLR and tumour mutational burden were independent prognostic factors of *** RNA-seq analysis revealed enriched neutrophil infiltration and a higher tumour NLR in the bNLR-high *** tumour gene-expression profiles were associated with neutrophil recruitment and inflammatory cytokine *** Our study demonstrated the potential clinical utility of NLR as a biomarker for patient selection and clinical management in predicting the prognosis of AGC patients as well as response to anti-PD-1 *** addition,high bNLR reflected the imbalance of tumour-tissue-infiltrating neutrophils and lymphocytes,and was associated with an

关键词： advanced gastric cancer neutrophil-to-lymphocyte ratio anti-PD-1 monoclonal antibody tumour microenvironment

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大型水陆两栖飞机海上最优搜索航路规划算法

吉林大学学报（工学版） 2019年第3期49卷 963-971页

作者：杨毅王斯财南英南京航空航天大学航天学院南京210016 中航通飞研究院有限公司广东珠海519000

针对大型水陆两栖飞机的飞行特性和远海搜索救援能力不足的问题,研究设计了海上最优搜索航路规划算法,使其能够在最短时间内完成规定海域的搜索。针对大型水陆两栖飞机的特性参数,结合漏搜率和复搜率的要求指标,将原搜索航路规划问题转... 详细信息

针对大型水陆两栖飞机的飞行特性和远海搜索救援能力不足的问题,研究设计了海上最优搜索航路规划算法,使其能够在最短时间内完成规定海域的搜索。针对大型水陆两栖飞机的特性参数,结合漏搜率和复搜率的要求指标,将原搜索航路规划问题转化为格点的离散规划问题。本文最优搜索航路规划算法在动态规划的基础上引入回溯路径指标,能够满足复搜率的要求。数值仿真分析结果表明:相对于传统的搜索路径方法,采用本文算法求得的最优航路方案具有更好的性能指标。

关键词：导航制导与控制导航技术航路规划改进动态规划远海搜索救援大型水陆两栖飞机

Under the Bourgeois Ideological Interpellation:An Althusserian Reading of Sons and Lovers

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海外英语 2017年第23期 173-175,181页

作者：张颖南北京外国语大学英语学院

"Under the Bourgeois Ideological Interpellation:An Althusserian Reading of Sons and Lovers"traces the authority behind the familial affairs and examines its influences on the individuals in ***’s masterpiece Sons and *** on the theory of Althusser’s"ideological interpellation",it explores the theme of bourgeois ideological interpellation within the working-class domestic sphere.

关键词： Sons and Lovers Althusser bourgeois ideology ideological interpellation

Usage of Molecular Pathology in a Rare Oral Tuberculosis Diagnosis

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Chinese Medical Journal 2017年第5期130卷 627-628页

作者： Wen-Juan Nie nan-ying Che Bao-Yun Cai Nai-Hui Chu Tuberculosis Department Beijing Chest Hospital Affiliated to Capital Medical University Beijing 101149 China Pathology Department Beijing Chest Hospital Affiliated to Capital Medical University Beijing 101149 China

To the Editor： A patient presented with oral mucosa, ulcerated pain, and limitation of mouth opening from January 2016. Local doctors diagnosed him with oral ulcer and prescribed courses of related medicine which did not relieve symptoms. Frozen section of oral mucosa （March 31, 2016） showed granulomatous reaction [Figure 1 ]. He was referred to our hospital.

关键词： Molecular Oral Diagnosis

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类BAN逻辑基本模型及缺陷

软件学报 2000年第12期11卷 1660-1665页

作者：许剑卓戴英侠左英男中国科学技术大学研究生院信息安全国家重点实验室北京100039

类 BA N逻辑是一种用于分析密码协议安全性的逻辑 .在分析了 BA N,A T,M B,G NY,SV O等类 BAN逻辑之后 ,指出这些逻辑的缺陷 ,包括若干新发现的缺陷 .首先把类 BA N的模型抽象出来 ,形成一个五元组模型 ,然后分析该模型的各个要素 ,并... 详细信息

类 BA N逻辑是一种用于分析密码协议安全性的逻辑 .在分析了 BA N,A T,M B,G NY,SV O等类 BAN逻辑之后 ,指出这些逻辑的缺陷 ,包括若干新发现的缺陷 .首先把类 BA N的模型抽象出来 ,形成一个五元组模型 ,然后分析该模型的各个要素 ,并依据该模型对类 BA N逻辑的缺陷进行分类 ,最后指出进一步发展类

关键词：密码协议 BAN逻辑缺陷

曝气池中气液两相流速度场分布的实验研究与数值模拟

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水利学报 2016年第10期47卷 1322-1331页

作者：王蒙孙楠王颖程文西安理工大学陕西省西北旱区生态水利工程国家重点实验室陕西西安710048 山西省水利建设开发中心山西太原030002 山西省水利水电科学研究院山西太原030002

气液两相流广泛存在于水利工程、废水处理等领域,其在气液装置中的流型流态及速度场分布可直接影响装置运行效能。本文采用实验研究与数值模拟相结合的方法,对圆柱形气液装置进行PIV实验,获得了准确的气液两相流气相速度场分布;在充分... 详细信息

气液两相流广泛存在于水利工程、废水处理等领域,其在气液装置中的流型流态及速度场分布可直接影响装置运行效能。本文采用实验研究与数值模拟相结合的方法,对圆柱形气液装置进行PIV实验,获得了准确的气液两相流气相速度场分布;在充分考虑湍流、曳力、升力、湍流分散力等作用下,采用欧拉-欧拉双流体模型和气泡群平衡模型对气液两相流流场进行了数值模拟,并将模拟结果与实验结果进行验证,所得结果误差控制在10%左右。结果表明,本文提出的模拟方法在气液两相流模拟中能够得到较准确的两相流动规律和速度场分布情况。

关键词：气液两相流粒子图像测速技术气泡群平衡模型速度场分布