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Inflammatory bowel disease: An increased risk factor for neurologic complications

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World Journal of Gastroenterology 2014年第5期20卷 1228-1237页

作者： Germán Morís neurology Department Hospital Universitario Central Asturias

Only a very few systematic studies have investigated the frequency of neurologic disorders in patients with Crohn’s disease (CD) and ulcerative colitis (UC), which are the two main types of inflammatory bowel disease (IBD). Results have been inconsistent and variable, owing to differences in case-finding methods and evaluated outcomes in different studies. The most frequent neurologic manifestations reported in CD and UC populations are cerebrovascular disease (with either arterial or venous events), demyelinating central nervous system disease, and peripheral neuropathy (whether axonal or demyelinating); however, the literature describes numerous nervous system disorders as being associated with IBD. The pathogenesis of nervous system tissue involvement in IBD has yet to be elucidated, although it seems to be related to immune mechanisms or prothrombotic states. The recently-introduced tumor necrosis factor (TnF) inhibitors have proven successful in controlling moderate to severe IBD activity. However, severe neurologic disorders associated with TnF inhibitors have been reported, which therefore raises concerns regarding the effect of anti-TnF-α antibodies on the nervous system. Although neurological involvement associated with IBD is rarely reported, gastroenterologists should be aware of the neurologic manifestations of IBD in order to provide early treatment, which is crucial for preventing major neurologic morbidity.

关键词： Extraintestinal manifestations Inflammatory bowel disease Multiple sclerosis neuropathy stroke Tumor necrosis factor inhibitor

Approximate analytical solutions and mean energies of stationary schrodinger equation for general molecular potential

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Chinese Physics B 2021年第7期30卷 116-131页

作者： Eyube E s Rawen B O Ibrahim n Department of Physics School of Physical SciencesModibbo Adama University of TechnologyP M B 2076 YolaAdamawa StateNigeria Directorate of Basic and Remedial studies Abubakar Tafawa Balewa University(ATBU)P M B 750001BauchiBauchi StateNigeria Department of Physics Faculty of ScienceP M B 1069MaiduguriBorno StateNigeria

The schrodinger equation is solved with general molecular potential via the improved quantization *** for bound state energy eigenvalues,radial eigenfunctions,mean kinetic energy,and potential energy are obtained in compact *** modeling the centrifugal term of the effective potential,a Pekeris-like approximation scheme is ***,we use the Hellmann–Feynman theorem to derive the relation for expectation *** state energy eigenvalues,wave functions and meanenergies of Woods–saxon potential,Morse potential,Mobius squared and Tietz–Hua oscillators are deduced from the general molecular *** addition,we use our equations to compute the bound state energy eigenvalues and expectation values for four diatomic molecules viz.H_(2),CO,HF,and O_(2).Results obtained are in perfect agreement with the data available from the literature for the potentials and *** also show that as the vibrational quantum number increases,the mean kinetic energy for the system in a Tietz–Hua potential increases slowly to a threshold value and then *** in a Morse potential,the mean kinetic energy increases linearly with vibrational quantum number increasing.

关键词： general molecular potential schrodinger equation improved quantization rule

synthesis and electrochemical properties of environmental free Lglutathione grafted graphene oxide/ZnO nanocomposite for highly selective piroxicam sensing

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Journal of Pharmaceutical Analysis 2021年第1期11卷 48-56页

作者： n.Dhanalakshmi T.Priya s.Thennarasu s.sivanesan n.Thinakaran Environmental Research Lab PG and Research Department of ChemistryAlagappa Government Arts CollegeKaraikudi630003Tamil NaduIndia school of Chemistry Bharathidasan UniversityThiruchirapalli620024Tamil NaduIndia Department of Applied science and Technology AC TechAnna UniversityChennai25India

A simple and reliable strategy was proposed to engineer the glutathione grafted graphene oxide/ZnO nanocomposite(glutathione-GO/ZnO)as electrode material for the high-performance piroxicam *** prepared glutathione-GO/ZnO nanocomposite was well characterized by X-ray diffraction(XRD),Fourier transform infrared spectrum(FTIR),X-ray photoelectron spectroscopy(XPs),field emission scanning electron microscopy(FE-sEM),cyclic voltammetry(CV),electrochemical impedance spectroscopy(EIs)and differential pulse voltammetry(DPV).The novel nanocomposite modified electrode showed the highest electrocatalytic activity towards piroxicam(oxidation potential is 0.52 V).Under controlled experimental parameters,the proposed sensor exhibited good linear responses to piroxicam concentrations ranging from 0.1 to 500 μ*** detection limit and sensitivity were calculated as 1.8 μM and 0.2 μA/μM·cm^(2),***,it offered excellent selectivity,reproducibility,and long-term stability and can effectively ignore the interfering candidates commonly existing in the pharmaceutical tablets and human fluids even at a higher ***,the reported sensor was successfully employed to the direct determination of piroxicam in practical samples.

关键词： Reduced graphene oxide Glutathione ZnO Piroxicam Electrochemical sensing

Dendritic spine degeneration:a primary mechanism in the aging process

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neural Regeneration Research 2025年第6期20卷 1696-1698页

作者： Gonzalo Flores Leonardo Aguilar-Hernández Fernado García-Dolores Humberto nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán Instituto de Fisiología Benemérita Universidad Autónoma de Puebla(BUAP)PueblaMexico Instituto de Ciencias Forenses(InCIFO) Tribunal Superior de Justicia de la Ciudad de México(TSJCDMX).Mexico CityMexico Instituto nacional de Medicina Genómica(InMEGEn) Mexico CityMexico

Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a wide range of factors, spanning from genetic to environmental factors, and even includes the gut microbiome(GM)(Mayer et al., 2022). All these processes coincide at some point in the inflammatory process, oxidative stress, and apoptosis, at different degrees in various organs and systems that constitute a living organism(Mayer et al., 2022;AguilarHernández et al., 2023).

关键词： aging process stress

Towards defining soil quality of Mediterranean calcareous agricultural soils:Reference values and potential core indicator set

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International soil and Water Conservation Research 2024年第1期12卷 145-155页

作者： Germán A.Durán Daniel sacristán Edelweis Farrús Jaume Vadell Institut de Recerca i FormacióAgrària i Pesquera de les Illes Balears C/Eusebi Estada14507009PalmaSpain Plant Biology Department University of Valencia46100BurjassotValenciaSpain soil and Environmental Quality Department Centro de Investigaciones sobre Desertificación-CIDE(CSIC-Universitat de València-Generalitat Valenciana)Carretera Moncada-Náquera km 4.546113MoncadaValenciaSpain Universitat de les Illes Balears Cra.De Valldemossakm 7507122PalmaSpain

To avoid soil degradation,adapt to climate change and comply with the sustainable Development goals 2030(Un General Assembly),establishing the quality/fertility of the agricultural soils of the Mediterranean region and evaluate how these evolve with time is *** enables adequate management practices to be *** Mediterranean calcareous region has received little attention in this sense,in spite its soil ***,24 different representative calcareous agricultural soils of the Mediterranean region,including the main management strategies of agricultural soils(rainfed and irrigated),were sampled from the island of Mallorca;and their physical,chemical and biological properties *** values obtained for most of the soil characteristics allowed to establish an initial approach to the reference values for the type of calcareous agricultural soils considered,and to clearly distinguish the effect of rainfed or irrigation management practices on soils properties and *** enzyme activities were not stimulated by the irrigation conditions assayed or they were only in dry conditions,suggesting optimum enzyme activities could be obtained when alternating dry and humid soil *** organic carbon,calcium carbonate and active lime revealed of significant importance in the collection of ***,the results obtained clearly indicate the heterogeneity of the region and its implications on the different soil ***,this study could serve as a starting point to adequately establish the quality(fertility)for Mediterranean calcareous agricultural soils and their reference values by conducting further research in this region and including more type of soils.

关键词： soil fertility Mediterranean agricultural soils Calcareous soils soil enzymes soil management

Bianchi Type-I Massive string Magnetized Barotropic Perfect Fluid Cosmological Model in the Bimetric Theory of Gravitation

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Chinese Physics Letters 2011年第8期28卷 368-371页

作者： n.P.Gaikwad M.s.Borkar s.s.Charjan Department of Mathematics Dharampeth M.P.Deo Memorial Science CollegeNagpur 440033India Post Graduate Department of Mathematics Mahatma Jyotiba Phule Educational CampusAmravati RoadR.T.M.Nagpur UniversityNagpur 440033India Department of Mathematics Late K.Z.S.Science CollegeBramhniKalmeshwar 441501 Dist.NagpurIndia

We investigate the Bianchi type-I massive string magnetized barotropic perfect fluid cosmological model in Rosen's bimetric theory of gravitation with and without a magnetic field by applying the techniques used by Latelier(1979,1980)and stachel(1983).To obtain a deterministic model of the universe,it is assumed that the universe is filled with barotropic perfect fluid *** physical and geometrical significance of the model are *** comparing our model with the model of Bali et al.(2007),it is realized that there are no big-bang and big-crunch singularities in our model and T=0 is not the time of the big bang,whereas the model of Bali et *** with a big bang at T=***,our model is in agreement with Bali et al.(2007)as time increases in the presence,as well as in the absence,of a magnetic field.

关键词： universe massive Perfect

Exact Controllability and Asymptotic Analysis for shallow shells

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Chinese Annals of Mathematics,series B 2007年第1期28卷 93-122页

作者： s.KAIZU n.sABU Department of Mathematics Faculty of Education Ibaraki University 2-1-1BunkyoMitoJapanDepartment of Mathematics Faculty of EducationIbaraki University2-1-1BunkyoMitoJapan

The authors consider the exact controllability of the vibrations of a thin shallow shell, of thickness 2ε with controls imposed on the lateral surface and at the top and bottom of the shell. Apart from proving the existence of exact controls, it is shown that the solutions of the three dimensional exact controllability problems converge, as the thickhess of the shell goes to zero, to the solution of an exact controllability problem in two dimensions.

关键词： Exact controllability Asymptotic analysis shallow shells

3D tomographic analysis of equatorial plasma bubble using Gnss-TEC data from Indonesian Gnss network

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Earth and Planetary Physics 2025年第1期9卷 127-136页

作者： Ihsan naufal Muafiry Prayitno Abadi Teguh n.Pratama Dyah R.Martiningrum sri Ekawati Yuandhika GWismaya Febrylian FChabibi Gatot HPramono Research Center for Climate and Atmosphere Indonesian National Research and Innovation Agency(BRIN)BandungIndonesia Indonesian Geospatial Information Agency(BIG) JakartaIndonesia Dept.of Physics Faculty of ScienceUniversiti Teknologi MalaysiaJohor BahruMalaysia Dept.Earth Planet sci. Hokkaido UniversitySapporoJapan school of Electrical Engineering Telkom UniversityBandungIndonesia

Equatorial Plasma Bubbles(EPBs)are ionospheric irregularities that take place near the magnetic *** most commonly occur after sunset during the equinox months,although they can also be observed during other *** phenomenon significantly disrupts radio wave signals essential to communication and navigation *** national network of Global navigation satellite system(Gnss)receivers in Indonesia(>30°longitudinal range)provides an opportunity for detailed EPB *** explore this,we conducted preliminary 3D tomography of total electron content(TEC)data captured by Gnss receivers following a geomagnetic storm on December 3,2023,when at least four EPB clusters occurred in the southeast Asian *** and extracted TEC depletion with a 120-minute running average were then used as inputs for a 3D tomography *** 2D spatial distribution consistently captured the four EPB clusters over *** tomography results were validated through a classical checkerboard test and comparisons with other ionospheric data sources,such as the Global Ionospheric Map(GIM)and International Reference Ionosphere(IRI)*** of the results demonstrates the capability of the Indonesian Gnss network to measure peak ionospheric *** findings highlight the potential for future three-dimensional research of plasma bubbles in low-latitude regions using existing Gnss networks,with extensive longitudinal coverage.

关键词： EPB Indonesian Gnss network 3D tomography

Investigations on luminescence of rare earths doped CaTiO_3:Pr^(3+) phosphor

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Journal of Rare Earths 2010年第4期28卷 488-492页

作者： n. suriyamurthy B.s. Panigrahi Radiological safety Division Technical services Division Indira Gandhi Centre for Atomic Research Kalpakkam-603 102 India

Calcium titanate doped with praseodymium was prepared through solid state reaction and it exhibited intense red emission at 612 nm. Phosphors were characterized for photoluminescence, thermo-luminescence and afterglow emissions. study of effects of rare earths on photoluminescence as well as afterglow intensity was reported. Presence of gadolinium enhanced luminescence. Presence of some monovalent ions enhanced both afterglow and photoluminescence emission. Thermo-luminescence glow curves were analyzed and ...

关键词： perovskites calcium titanates red afterglow rare earths