检索结果-南通市图书馆

Effect of Graphene nanoribbons (TexasPEG) on locomotor function recovery in a rat model of lumbar spinal cord transection

引用

neural Regeneration Research 2018年第8期13卷 1440-1446页

作者： C-Yoon kim William k. A. Sikkema Jin kim Jeong Ah kim James Walter Raymond Dieter Hyung-Min Chung Andrea Mana James M. Tour Sergio Canavero Department of Stem Cell Biology School of Medicine Konkuk University Seoul Korea Department of Laboratory Animal Medicine College of Veterinary Medicine Seoul National University Seoul Korea Department of Chemistry Department of Materials Science and NanoEngineering and The NanoCarbon Center Rice University Houston TXUSA Biomedical Omics Group Korea Basic Science Institute Cheongju-si Chungbuk Korea Research Service Hines Veterans Administration Hospital Hines IL USA HEAVEn/GEMInI International Collaborative Group Turin Italy

A sharply transected spinal cord has been shown to be fused under the accelerating influence of membrane fusogens such as polyethylene glycol （PEG）（GEMInI protocol）. Previous work provided evidence that this is in fact possible. Other fusogens might improve current results. In this study, we aimed to assess the effects of PEGylated graphene nanoribons （PEG-GnR, and called ＂TexasPEG＂ when prepared as lwt% dispersion in PEG600） versus placebo （saline） on locomotor function recovery and cellular level in a rat model of spinal cord transection at lumbar segment 1 （L1） level. In vivo and in vitro experiments （n -- 10 per experiment） were designed. In the in vivo experiment, all rats were submitted to full spinal cord transection at L1 level. Five weeks later, behavioral assessment was performed using the Basso Beattie Bresnahan （BBB） locomotor rating scale. Immunohistochemical staining with neuron marker neurofilament 200 （nF200） antibody and astrocyt- ic scar marker glial fibrillary acidic protein （GFAP） was also performed in the injured spinal cord. In the in vitro experiment, the effects of TexasPEG application for 72 hours on the neurite outgrowth of SH-SYSY cells were observed under the inverted microscope. Results of both in vivo and in vitro experiments suggest that TexasPEG reduces the formation of glial scars, promotes the regeneration of neurites, and thereby contributes to the recovery of locomotor function of a rat model of spinal cord transfection.

关键词： nerve regeneration spinal cord transfection spinal cord fusion GEMInI TexasPEG graphene nanoribbons

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical-based phenotypes in children with pediatric post-COVID-19 condition

引用

World Journal of Pediatrics 2024年第7期20卷 682-691页

作者： Lieke C.E.noij Jelle M.Blankestijn Coen R.Lap Marlies A.van Houten Giske Biesbroek Anke-Hilse Maitland-van der Zee Mahmoud I.Abdel-Aziz Johannes B.van Goudoever Mattijs W.Alsem Caroline L.H.Brackel kim J.Oostrom Simone Hashimoto Suzanne W.J.Terheggen-Lagro Department of Pediatric Pulmonology and Allergy Amsterdam UMCLocation AMCEmma Children’s HospitalAmsterdam University Medical CenterRoom G2-222Meibergdreef 91105AZAmsterdamThe Netherlands Department of Pulmonary Medicine Amsterdam UMCAmsterdamThe Netherlands Department of Pediatrics Spaarne GasthuisHoofddorpThe Netherlands Department of Pediatrics Emma Children’s HospitalAmsterdam University Medical CenterAmsterdamThe Netherlands Department of Rehabilitation Medicine Amsterdam Movement SciencesMeibergdreef 9AmsterdamThe Netherlands Department of Paediatric Pulmonology Department of PaediatricsTergooi MCHilversumThe Netherlands Department of Child and Adolescent Psychiatry and Psychosocial Care Amsterdam UMCAmsterdam Reproduction and DevelopmentAmsterdamThe Netherlands

Background Pediatric post coronavirus disease 2019(COVID-19)condition(PPCC)is a heterogeneous syndrome,which can significantly affect the daily lives of *** study aimed to identify clinically meaningful phenotypes in children with PPCC,to better characterize and treat this *** Participants were children with physician-diagnosed PPCC,referred to the academic hospital Amsterdam UMC in the netherlands between november 2021 and March *** factors and information on post-COVID symptoms,comorbidities,and impact on daily life were *** clusters were identified using an unsupervised and unbiased approach for mixed data *** Analysis of 111 patients(aged 3–18 years)revealed three distinct clusters within *** 1(n=62,median age=15 years)predominantly consisted of girls(74.2%).These patients suffered relatively more from exercise intolerance,dyspnea,and smell *** 2(n=33,median age=13 years)contained patients with an even gender distribution(51.5%girls).They suffered from relatively more sleep problems,memory loss,gastrointestinal symptoms,and *** 3(n=16,median age=11 years)had a higher proportion of boys(75.0%),suffered relatively more from fever,had significantly fewer symptoms(median of 5 symptoms compared to 8 and 10 for clusters 1 and 2 respectively),and experienced a lower impact on daily *** This study identified three distinct clinical PPCC phenotypes,with variations in sex,age,symptom patterns,and impact on daily *** findings highlight the need for further research to understand the potentially diverse underlying mechanisms contributing to post-COVID symptoms in children.

关键词： Adolescents Clusters Long COVID Pediatric Phenotypes Post-COVID syndrome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microglia as hackers of the matrix:sculpting synapses and the extracellular space

引用

Cellular & Molecular Immunology 2021年第11期18卷 2472-2488页

作者： Joshua D.Crapser Miguel A.Arreola kate I.Tsourmas kim n.Green Department of neurobiology and Behavior University of CaliforniaIrvineCAUSA

Microglia shape the synaptic environment in health and disease,but synapses do not exist in a ***,pre-and postsynaptic terminals are surrounded by extracellular matrix(ECM),which together with glia comprise the four elements of the contemporary tetrapartite synapse *** research in this area is still just beginning,accumulating evidence points toward a novel role for microglia in regulating the ECM during normal brain homeostasis,and such processes may,in turn,become dysfunctional in *** it relates to synapses,microglia are reported to modify the perisynaptic matrix,which is the diffuse matrix that surrounds dendritic and axonal terminals,as well as perineuronal nets(Pnns),specialized reticular formations of compact ECM that enwrap neuronal subsets and stabilize proximal *** interconnected relationship between synapses and the ECM in which they are embedded suggests that alterations in one structure necessarily affect the dynamics of the other,and microglia may need to sculpt the matrix to modify the synapses ***,we provide an overview of the microglial regulation of synapses,perisynaptic matrix,and Pnns,propose candidate mechanisms by which these structures may be modified,and present the implications of such modifications in normal brain homeostasis and in disease.

关键词： neuroscience Perineuronal nets Microglia Extracellular matrix neuroinflammation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Spectroscopic properties of Er3+/Ho3+/Tm3+ doped α-SiAlOn ceramics under 793 nm excitation

引用

Progress in natural Science:Materials International 2021年第6期31卷 891-897页

作者： Bina Chaudhary Dhani Ram Dhakal Tae-Ho kim Soo Wohn Lee Yuwaraj k.kshetri Department of Fusion Science and Technology Sun Moon University Research Center for Eco-Multifunctional nano Materials Sun Moon University Department of Environment and Bio-Chemical Engineering Sun Moon University

This paper reports the first demonstration of super broadband infrared downshifting emission extending from1640 nm to 2200 nm with the full width at half maximum of ～ 417 nm in lanthanides(Er3+, Ho3+, and Tm3+)-doped α-SiAlOn ceramics upon 793 nm excitation. Using α-Si3n4ceramic as a precursor the lanthanides-dopedα-SiAlOn ceramics were synthesized by the hot-press method. The lanthanides induced no significant secondary phases in the sintered α-SiAlOn ceramics. Strong two-photon upconversion emission bands centered at 547,671 and 694 nm have also been observed upon 793 nm excitation. The time-resolved measurements of the upconversion emissions confirm that the efficient energy transfer among the Er3+, Ho3+and Tm3+ions as well as the ground state absorption in Er3+and Tm3+are responsible for the observed spectroscopic properties.

关键词： α-SiAlOn Upconversion Downshifting 793 nm excitation

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Computational approaches for fast generation of digital 3D video holograms(Invited Paper)

引用

Chinese Optics Letters 2009年第12期7卷 1083-1091页

作者： Seung-Cheol kim Eun-Soo kim 3D Display Research Center Department of Electronic Engineering Kwangwoon University

Several approaches for fast generation of digital holograms of a three-dimensional （3D） object have been discussed. Among them, the novel look-up table （n-LUT） method is analyzed to dramatically reduce the number of pre-calculated fringe patterns required for computation of digital holograms of a 3D object by employing a new concept of principal fringe patterns, so that problems of computational complexity and huge memory size of the conventional ray-tracing and look-up table methods have been considerably alleviated. Meanwhile, as the 3D video images have a lot of temporally or spatially redundant data in their inter- and intra-frames, computation time of the 3D video holograms could be also reduced just by removing these redundant data. Thus, a couple of computational methods for generation of 3D video holograms by combined use of the n-LUT method and data compression algorithms are also presented and discussed. Some experimental results finally reveal that by using this approach a great reduction of computation time of 3D video holograms could be achieved.

关键词： LUT Computational approaches for fast generation of digital 3D video holograms CGH

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Inexpensive synthesis of a high-performance Fe3O4-SiO2-TiO2 photocatalyst： Magnetic recovery and reuse

引用

Frontiers of Chemical Science and Engineering 2016年第3期10卷 405-416页

作者： nadir Abbas Godlisten n. Shao Syed M. Imran Muhammad S. Haider Hee Taik kim Department of Chemical Engineering Hanyang University Ansan-si Gyeonggi-do 426-791 Republic of Korea Department of Civil and Environmental Engineering Hanyang University Ansan-si Gyeonggi-do 426-791 Republic of Korea Department of Chemical Engineering University of Gujrat HH Campus Punjab Pakistan

A sol-gel technique has been developed for the synthesis of a magnetite-silica-titania （Fe3O4-SiO2-TiO2） tertiary nanocomposite with improved photocatalytic properties based on the use of inexpensive titania and silica precursors. The exceptional photocatalytic activity of the resulting materials was demonstrated by using them to photocatalyze the degradation of methylene blue solution. The best formulation achieved 98% methylene blue degradation. An interesting feature of the present work was the ability to magnetically separate and reuse the catalyst. The efficiency of the catalyst remained high during two reuses. The synthesized nanomaterials were characterized by X-ray diffraction （XRD）, scanning electron microscopy （SEM）, transmission electron micro- scopy （TEM）, Fourier transform infrared （FTIR） spectro- scopy, ultra-violet-visible spectroscopy, diffuse reflectance spectroscopy, and thermogravimetric analysis. XRD ana- lysis revealed the formation of multicrystalline systems of cubic magnetite and anatase titania crystals. SEM and TEM characterization revealed well-developed and homo- geneously dispersed particles of size less than 15 nm. FTIR spectra confirmed the chemical interaction of titania and silica. It was further noticed that the optical properties of the prepared materials were dependent on the relative contents of their constituent metal oxides.

关键词： sol-gel photocatalysis magnetic recovery,TiO2 Fe3O4 SiO2

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparative study of Sm^(3+) ions doped phosphate based oxide and oxy-fluoride glasses for solid state lighting applications

引用

Journal of Rare Earths 2019年第4期37卷 374-382页

作者： M.Shoaib G.Rooh R.Rajaramakrishna n.Chanthima n.kiwsakunkran H.J.kim J.kaewkhao S.Tuscharoen Department of Physics Abdul Wali Khan University Center of Excellence in Class Technology and Materials Science (CEGM) Nakhon Pathom Rajabhat University Physics Program Faculty of Science and TechnologyNakhon Pathom Rajabhat University Department of Physics Kyungpook National University

The physical and luminescent properties of Sm^(3+)-doped oxide and oxy-fluoride phosphate glasses were investigated. The glass samples with chemical composition of 69 P_2 O_5-10 BaO-10 ZnO-10 Gd_2 O_3-1 Sm_2 O_3 and 69 P_2 O_5-10 BaO-10 ZnO-10 GdF_3-1 Sm_2 O_3 were prepared by conventional melt quenching technique. The prepared glass samples were characterized with density, molar volume, refractive index,FTIR, UV-Vis-nIR, photo luminesce nce, radio luminescence, decay time profile and CIE diagram. The density and refractive index of the oxide glass have higher values as compared to the oxy-fluoride *** FTIR spectra show the reduction of O-H group in oxy-fluoride glass. The characteristic peaks of Sm^(3+)are observed at 360,372,402,438,419,473,944,1077,1227,1373,1474,1529 and 1585 nm in UV-VIS-nIR spectra. These peaks are related respectively to the transitions from ground state ~6 H_(5/2) to ~4 D_(3/2), ~6 P_(7/2),6 P3/2, ~4 I_(11/2), ~6 F_(11/2), ~6 F_(9/2), ~6 F_(7/2),~6 F_(5/2),~6 F_(3/2), ~6 H_(15/2) and ~6 F_(1/2) excited states. From photoluminescence and radio-luminesce nce it is observed that the oxy-fluoride glass samples show better emission intensity than the oxide glass. The Judd-Ofelt theory(J-0 theory) was used to find J-O intensity Ω_λ(λ = 2,4 and 6)parameters and radiative properties such as transition probability, stimulated emission cross section and branching ratios for titled glasses. The trend observed in the J-O parameters is Ω_4 >Ω_2 >Ω_6. The transition probability,emission cross section and branching ratio have the highest values for the ~4 G_(5/2)→~6 H_(7/2)transition. The CIE coordinates of the prepared glass samples are positioned in the orange region and the CCT value is 3776.105 for oxide and oxyfluoride glass. The oxy-fluoride glass has shorter decay time as compared to the oxide glass and it is recorded to be 1.62 and 1.32 ms for oxide and oxy-fluoride respectively. According to the results obtained in this work, it is obvious t

关键词： Oxy-fluoride glass Photoluminescence Judd-Ofelt theory CIE coordinates Rare earths

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fabrication of Graphitic Carbon nitride-Based Film:An Emerged Highly Efficient Catalyst for Direct C-H Arylation under Solar Light

引用

Chinese Journal of Chemistry 2021年第3期39卷 633-639页

作者： Surabhi Chaubey Rajesh k.Yadav Tae Wu kim Tara Chand Yadav Abhishek kumar D.k.Dwivedi B.k.Pandey Atul P.Singh Department of Chemistry and Environmental Science Madan Mohan Malaviya University of TechnologyGorakhpur-273010U.PIndia Center for nanomaterials and Chemical Reactions Institute for Basic Science(IBS)Daejeon 34141Republic of Korea Department of Chemistry Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of Biotechnology Indian Institute of Technology Roorkee-247667India Department of Chemistry Institute of ScienceBanaras Hindu UniversityIndia Department of Physics and Material Science Madan Mohan Malaviya University of TechnologyGorakhpur 273010U.PIndia Department of Chemistry Chandigarh UniversityMohaliIndia

Main observation and conclusion Photoredox C-H bond formation can proceed in aerobic environment under solar light and has therefore become ***-days,different types of expensive novel metal complexes and nanomaterials have been urbanized as photocatalysts for direct C-H bond formation in between derivatives of heteroarenes(HAs)and aryl diazonium *** photocatalysts,however,still suffer from poor stability,high cost,and ***,a graphitic carbon nitride-based fluorescein isothiocyanate(g-C_(3)n_(4)-FITC)film pho-tocatalyst has been reported,which shows ecellent light harvesting ability,and band gap suitability to catalyze the metal free direct C-H arylation of HAs under solar light at ambient ***,the g-C_(3)n_(4)-FITC film photocatalyst can be reused four times without significant loss of activity,confirming the excellent photocatalytic *** current strategy to constructa g-C_(3)n_(4)-FITC film photocatalyst for direct C-H arylation opens a new path towards replacing metal-based catalysts in fine chemical Sy nthesis.

关键词： Photocatalysis g-C_(3)n_(4)-FITC film photocatalyst C-H activation Heteroarenes Cyclic voltammetry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8^(+) T cell proliferation

引用

Cellular & Molecular Immunology 2017年第9期14卷 748-757页

作者： Beom k Choi Do Y Lee Don G Lee Young H kim Seon-Hee kim Ho S Oh Chungyong Han Byoung S kwon Cancer Immunology Branch Division of Cancer BiologyNational Cancer CenterGoyangGyeonggi 10408Korea Department of Internal Medicine Yonsei University College of MedicineSeoul 120-752Korea Immune Cell Production Unit Program for Immunotherapeutic ResearchNational Cancer CenterGyeonggi 10408Korea Eutilex Catholic University School of MedicineSeoul 06591Korea Department of Medicine Tulane University Health Sciences CenterNew OrleansLA 70112USA

4-1BB(CD137)is a strong enhancer of the proliferation of CD8^(+)T *** these cells require increased production of energy and biomass to support their proliferation,we hypothesized that 4-1BB signaling activated glucose and fatty acid *** found that treatment with agonistic anti-4-1BB mAb promoted the proliferation of CD8^(+)T cells in vitro,increasing their size and *** with a glycolysis inhibitor and a fatty acid oxidation inhibitor revealed that CD8^(+)T cell proliferation required both glucose and fatty acid ***-4-1BB treatment increased glucose transporter 1 expression and activated the liver kinase B1(LkB1)-AMP-activated protein kinase(AMPk)-acetyl-CoA carboxylase(ACC)signaling pathway,which may be responsible for activating the metabolism of glucose and fatty *** also examined whether blocking glucose or fatty acid metabolism affected cell cycle progression and the anti-apoptotic effect of 4-1BB *** increase of anti-apoptotic factors and cyclins in response to anti-4-1BB treatment was completely prevented by treating CD8^(+)T cells with the fatty acid oxidation inhibitor,etomoxir,but not with the glycolysis inhibitor,*** conclude that anti-4-1BB treatment activates glucose and fatty acid metabolism thus supporting the increased demand for energy and biomass,and that fatty acid metabolism plays a crucial role in enhancing the cell cycle progression of anti-CD3-activated CD8^(+)T cells in vitro and the anti-apoptotic effects of 4-1BB signaling on these cells.

关键词： AMPk CD8^(+)T cells 4-1BB(CD137) LkB1 metabolism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photocatalysts for degradation of dyes in industrial effluents:Opportunities and challenges

引用

nano Research 2019年第5期12卷 955-972页

作者： Hassan Anwer Asad Mahmood Jechan Lee ki-Hyun kim Jae-Woo Park Alex C.k.Yip Department of Civil and Environmental Engineering Hanyang University222 Wangsimni-roSeoul 04763Republic of Korea Department of Environmental and Safety Engineering Ajou UniversitySuwon 16499Republic of Korea Department of Chemical and Process Engineering University of CanterburyChristchurch 8041New Zealand

Discharging dye contaminants into water is a major concern around the *** a variety of methods to treat dye-contaminated water,photocatalytic degradation has gained attention as a tool for treating the colored ***,we review the recent advancements in photocatalysis for dye degradation in industrial effluents by categorizing photocatalyst materials into three *** generation photocatalysts are composed of single-component materials (e.g.,TiO2,ZnO,and CdS),while second generation photocatalysts are composed of multiple components in a suspension (e.g.,WO3/niWO4,BiOl/ZnTiOa,and C3n4/Ag3VO4).Photocatalysts immobilized on solid substrates are regarded as third generation materials (e.g.,FTO/WO3-ZnO,Steel/TiO2-WO3,and Glass/P-TiO2).Photocatalytic degradation mechanisms,factors affecting the dye degradation,and the lesser-debated uncertainties related to the photocatalysis are also discussed to offer better insights into environmental ***,quantum yields of different photocatalysts are calculated,and a performance evaluation method is proposed to compare photocatalyst systems for dye ***,we discuss the present limitations of photocatalytic dye degradation for field applications and the future of the technology.

关键词： photocatalyst dye wastewater degradation mechanism performance evaluation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：