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Faster Region Convolutional neural network(FRCnn)Based Facial Emotion Recognition

Computers, Materials & Continua 2024年第5期79卷 2427-2448页

作者： J.Sheril Angel A.Diana Andrushia TMary neebha Oussama Accouche Louai Saker n.anand Department of Electronics and Communication Engineering Karunya Institute of Technology and SciencesCoimbatore641114India College of Engineering and Technology American University of the Middle EastEgaila54200Kuwait Department of Civil Engineering Karunya Institute of Technology and SciencesCoimbatore641114India

Facial emotion recognition(FER)has become a focal point of research due to its widespread applications,ranging from human-computer interaction to affective *** traditional FER techniques have relied on handcrafted features and classification models trained on image or video datasets,recent strides in artificial intelligence and deep learning(DL)have ushered in more sophisticated *** research aims to develop a FER system using a Faster Region Convolutional neural network(FRCnn)and design a specialized FRCnn architecture tailored for facial emotion recognition,leveraging its ability to capture spatial hierarchies within localized regions of facial *** proposed work enhances the accuracy and efficiency of facial emotion *** proposed work comprises twomajor key components:Inception V3-based feature extraction and FRCnn-based emotion *** experimentation on Kaggle datasets validates the effectiveness of the proposed strategy,showcasing the FRCnn approach’s resilience and accuracy in identifying and categorizing facial *** model’s overall performance metrics are compelling,with an accuracy of 98.4%,precision of 97.2%,and recall of 96.31%.This work introduces a perceptive deep learning-based FER method,contributing to the evolving landscape of emotion recognition *** high accuracy and resilience demonstrated by the FRCnn approach underscore its potential for real-world *** research advances the field of FER and presents a compelling case for the practicality and efficacy of deep learning models in automating the understanding of facial emotions.

关键词： Facial emotions FRCnn deep learning emotion recognition face Cnn

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An Interoperability Cross-Block Chain Framework for Secure Transactions in IoT

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Computer Systems Science & Engineering 2023年第10期47卷 1077-1090页

作者： n.anand Kumar A.Grace Selvarani P.Vivekanandan Department of IT SNS College of TechnologyCoimbatoreTamilnadu641035India Department of CSE Sri Ramakrishna Engineering CollegeCoimbatoreTamilnadu641035India Department of CSE Park College of Engineering and TechnologyCoimbatoreTamilnadu641035India

The purpose of this research is to deal with effective block chain framework for secure *** rate of effective data transactions and the interoperability of the ledger are the two major obstacles involved in Blockchain and to tackle this issue,Cross-Chain based Transaction(CCT)is *** industries have been restructured by the introduction of Internet of Things(IoT)to become smart industries through the feature of data-driven ***,there are a few limitations,like decentralization,security vulnerabilities,poor interoperability,as well as privacy concerns in *** overcome this limitation,Blockchain has been employed to assure a safer transaction process,especially in asset *** recent decades,scalable local ledgers implement Blockchains,simultaneously sustaining peer validations of transactions which can be at local or global *** the single Hyperledger-based blockchains system,the CCT takes the transaction amid various *** addition,the most significant factor for this registration processing strategy is the Signature to ensure *** application of the Quantum cryptographic algorithm amplifies the proposed Hyperledger-based blockchains,to strengthen the safety of the *** key has been determined by restricting the number of transactions that reach the global Blockchain using the quantum-based hash function and accomplished by scalable local ledgers,and peer validations of transactions at local and global levels without any *** rate of transaction processing for entire peers has enhanced with the ancillary aid of the proposed solution,as it includes the procedure of load *** any boosted enhancement,the recommended solution utilizes the current transaction strategy,and also,it’s aimed at scalability,resource conservation,and *** experimental results of the system have been evaluated using the metrics like block weight,ledger memory,the usage of the

关键词： Internet of Things(IoT) scalability blockchain interoperability security ledger size transaction rate cross-chain based transaction(CCT) quantum cryptographic algorithm

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TRAnSCOnJUnCTIVAL OOZInG AFTER GLAUCOMA SURGERY

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国际眼科杂志 2003年第1期3卷 19-19页

作者： n.anand P.P.Syam C.Atherley Calderdale Royal Hospital UKCalderdale Royal Hospital UKCalderdale Royal Hospital UK

Aim: To study the prevalence of filtration-bleb transconjunctival oozing in the first postoperative year after various glaucoma procedures. Methods: Cross-sectional, single-point examination of all filtration blebs in eyes which had glaucoma surgery in the last year. Eyes were examined 3-12 months after surgery and were grouped into non-penetrating (nPGS) and penetrating (PGS)

关键词：青光眼眼外科手术术后经结膜渗液

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SLIT-LAMP EXTERnAL nEEDLE REVI- SIOn WITH SUBCOnJUnCTIVAL 5- FLU- OROURACIL FOR DELAYED FAILURE OF TRABECULECTOMY

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国际眼科杂志 2003年第1期3卷 61-61页

作者： P.P.Syam C.Atherly n.anand Calderdale Royal Hospital UKCalderdale Royal Hospital UKCalderdale Royal Hospital UK

Aim: To evaluate the safety and efficacy of needle revision with subconjunctival injection of 5-Fluorouracil with late failure of trabeculectomy on the slit-lamp bio microscope. Methods: 31 eyes of 31 patients were included in the study. Eyes with encapsulated blebs were excluded. After informed consent the procedure was done with an appropriate gauge needle and 5mg of

关键词：小梁切除术迟发性手术失败裂隙灯针头修整 5-FLU 结膜下注射

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LC,MS^n and LC-MS/MS studies for the characterization of degradation products of amlodipine

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Journal of Pharmaceutical Analysis 2015年第1期5卷 33-42页

作者： Ravi n.Tiwari nishit Shah Vikas Bhalani anand Mahajan Department of Pharmaceutical Chemistry SVKM's NMIMSSchool of Pharmacy and Technology ManagementNear Bank of Tapi RiverAgra-Mumbai RoadBabuldeShirpurDist.Dhule 425405MaharashtraIndia Department of Pharmaceutical Chemistry Sinhgad Institute of PharmacyPuneMaharashtraIndia

In the present study,comprehensive stress testing of amlodipine（AM） was carried out according to International Conference on Harmonization（ICH） Q1A（R2） *** was subjected to acidic,neutral and alkaline hydrolysis,oxidation,photolysis and thermal stress *** drug showed instability in acidic and alkaline conditions,while it remained stable to neutral,oxidative,light and thermal stress.A total of nine degradation products（DPs） were formed from *** could be separated by the developed gradient LC method on a C18 *** products formed under various stress conditions were investigated by LC-MS/MS *** previously developed LC method was suitably modified for LC-MS/MS studies by replacing phosphate buffer with ammonium acetate buffer of the same concentration（pH 5.0）.A complete fragmentation pathway of the drug was first established to characterize all the degradation products using LC-MS/MS and multi-stage mass（MS^n） fragmentation *** obtained mass values were used to study elemental compositions,and the total information helped with the identification of *** with its degradation pathway.

关键词： Amlodipine LC-MS/MS Characterization Degradation pathway

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nucleoside modified mRnA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord

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neural Regeneration Research 2025年第8期20卷 2311-2312页

作者： Krisztián Pajer Tamás Bellák Antal nógrádi Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spinal cord injury and treatment opportunities:The adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular *** the spinal cord neurons have the capacity to regenerate their axons,the expression of growth inhibitory factors,lack or suppression of proper guidance cues,and profound inflammatory responses do not permit successful regeneration(Khyeam et al.,2021).

关键词： injured capacity modified

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Green ionic metal-organic frameworks as nanocatalysts for CO_(2)fixation

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nano Research 2025年第1期18卷 260-269页

作者： nuria Martín Miguel Maireles-Porcar Julián Sánchez Velandia Belén Altava Francisco G.Cirujano Eduardo García-Verdugo Departamento de Química Inorgánica y Orgánica Universidad Jaume IAv.Sos Baynats/nCastellóde la PlanaCastellón 12071Spain

Co,ni,and Zn iso-reticular coordination polymers of 2,5-dihydroxyterphthalic acid(H_(2)dot)can be rapidly obtained under room temperature and aqueous conditions using either sodium or ammonium hydroxide as the bases to deprotonate the *** use of metal bromides and tetrabutylammonium hydroxide(TBAOH)as the base allows the green synthesis of ionic metal-organic frameworks(MOFs),characterized by X-ray diffraction(XRD),Fourier transform infrared(FTIR),scanning electron microscopy(SEM),thermo gravimetric analysis(TGA),H-nuclear magnetic resonance(nMR),elemental analysis,and X-ray photoelectron spectroscopy(XPS),and employed in the pressure,solvent,and additive-free CO_(2)fixation to epoxides by its cycloaddition to epichlorohydrin,exhibiting a cooperative behavior between the MOF and the ionic liquid formed within the framework,achieving TOns of the confined tetrabutylammonium bromide(TBABr)up to 700.

关键词： metal-organic frameworks(MOFs) ionic liquids heterogeneous catalysis CO_(2)conversion

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Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions

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neural Regeneration Research 2025年第4期20卷 1031-1041页

作者： Ramón Pérez-núñez María Fernanda González Ana María Avalos Lisette Leyton Cellular Communication Laboratory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile Advanced Center for Chronic Diseases(ACCDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile Instituto de Ciencias Biomédicas Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

Astrocytes are the most abundant type of glial cell in the central nervous *** injury and inflammation,astrocytes become reactive and undergo morphological and functional *** on their phenotypic classification as A1 or A2,reactive astrocytes contribute to both neurotoxic and neuroprotective responses,***,this binary classification does not fully capture the diversity of astrocyte responses observed across different diseases and *** analysis has revealed that reactive astrocytes have a complex landscape of gene expression profiles,which emphasizes the heterogeneous nature of their *** actively participate in regulating central nervous system inflammation by interacting with microglia and other cell types,releasing cytokines,and influencing the immune *** phosphoinositide 3-kinase(PI3K)/protein kinase B(AKT)signaling pathway is a central player in astrocyte reactivity and impacts various aspects of astrocyte behavior,as evidenced by in silico,in vitro,and in vivo *** astrocytes,inflammatory cues trigger a cascade of molecular events,where nuclear factor-κB serves as a central mediator of the pro-inflammatory ***,we review the heterogeneity of reactive astrocytes and the molecular mechanisms underlying their *** highlight the involvement of various signaling pathways that regulate astrocyte reactivity,including the PI3K/AKT/mammalian target of rapamycin(mTOR),αvβ3 integrin/PI3K/AKT/connexin 43,and notch/PI3K/AKT *** targeting the inactivation of the PI3K/AKT cellular signaling pathway to control reactive astrocytes and prevent central nervous system damage,evidence suggests that activating this pathway could also yield beneficial *** dual function of the PI3K/AKT pathway underscores its complexity in astrocyte reactivity and brain function *** review emphasizes the importance of employing astrocyte-exclusive models to underst

关键词： inflammation integrins neuroprotective neurotoxic phosphatidylinositol 3-kinase reactive astrocytes signal transduction Thy-1(CD90)

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Astrocytes, reactive astrogliosis, and glial scar formation in traumatic brain injury

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neural Regeneration Research 2025年第4期20卷 973-989页

作者： María Belén Cieri Alberto Javier Ramos Laboratorio de neuropatología Molecular IBCN UBA-CONICETFacultad de MedicinaUniversidad de Buenos AiresBuenos AiresArgentina

Traumatic brain injury is a global health crisis,causing significant death and disability *** that follows traumatic brain injury has serious consequences for neuronal survival and cognitive impairments,with astrocytes involved in this *** traumatic brain injury,astrocytes rapidly become reactive,and astrogliosis propagates from the injury core to distant brain *** astroglial proteins are downregulated near the traumatic brain injury core,while pro-inflammatory astroglial genes are *** altered gene expression is considered a pathological remodeling of astrocytes that produces serious consequences for neuronal survival and cognitive *** addition,glial scar formed by reactive astrocytes is initially necessary to limit immune cell infiltration,but in the long term impedes axonal reconnection and functional *** therapeutic strategies for traumatic brain injury are focused on preventing acute ***,cannabinoids,progesterone,beta-blockers,and cerebrolysin demonstrate neuroprotective benefits but most of them have not been studied in the context of *** this review,we discuss the cell signaling pathways activated in reactive astrocytes following traumatic brain injury and we discuss some of the potential new strategies aimed to modulate astroglial responses in traumatic brain injury,especially using cell-targeted strategies with miRnAs or lncRnA,viral vectors,and repurposed drugs.

关键词： astrocyte glial scar innate immunity neuroinflammation stab injury Toll-like receptors

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Sex differences in aging and injured brain

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neural Regeneration Research 2025年第10期20卷 2901-2902页

作者： Jordan n.Williamson Yuan Yang University of Illinois Urbana-Champaign Grainger College of EngineeringDepartment of BioengineeringUrbanaILUSA Carle Foundation Hospital Stephenson Family Clinical Research InstituteClinical Imaging Research CenterUrbanaILUSA University of Illinois Urbana-Champaign Beckman Institute for Advanced Science and TechnologyUrbanaILUSA northwestern University Department of Physical Therapy and Human Movement SciencesChicagoILUSA

Background:The prevalence,age of onset,and symptomatology of traumatic brain injury,stroke,and neurodegenerative diseases(such as Alzheimer’s disease(AD),Parkinson’s disease,amyotrophic lateral sclerosis,and Huntington’s disease)differ substantially between males and *** higher prevalence of these brain disorders has been attributed to females having a greater longevity compared with *** one of the greatest risk factors of acquired brain injury(such as stroke,traumatic brain injury caused by fall)and neurodegenerative disease is age.

关键词： Huntington prevalence traumatic

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