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Life Origin.in.the Milky w.y Galaxy: II. Scan.in. for Habitable Stellar Systems on.Behalf of Future Space Mission.

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Journ.l of High En.rgy Physics, Gravitation.an. Cosmology 2024年第2期10卷 681-692页

作者： Alexan.er n. Safron.v Obukhov In.titute of Atmospheric Physics Russian Academy of Sciences Moscow Russia

The possibility of the life origin.in.the stellar systems, located at a distan.e of ~200 pc from the solar system, w.s in.estigated. The stars, in.the spectrums of w.ich C (carbon., O (oxygen., n.(n.trogen., an. P (phosphorus) are foun., are called Dn.-stars. Based on.stellar abun.an.es a n.w.method for searchin. for habitable exoplan.ts has been.developed an. a list of 48 Dn.-stars in.the solar n.ighborhood, on.w.ich life is possible, has been.defin.d. The quota of Dn.-stars is equal 1.3% of the total amoun. of Hypatia Stellar Catalog. On.y three Dn.-stars out of selected 48 stars belon. to the spectral class as our Sun.(G2V). The closest to the solar system is the Dn.-star w.th the n.mber HIP 15510, w.ich belon.s to the G8V class an. is 6 pc aw.y from the solar system. n.n. Dn.-stars, w.ich have the highest chemical similarity w.th solar spectrum, w.re iden.ified. It is iden.ified that on. of these n.n. stars, HIP 24681, has six plan.ts.

关键词： In.erstellar Mission Stellar Abun.an.e Habitability Hypatia Stellar Catalog Dn.-Star

Life Origin.in.the Milky w.y Galaxy: I. The Stellar n.cleogen.sis of Elemen.s n.cessary for the Life Origin

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Journ.l of High En.rgy Physics, Gravitation.an. Cosmology 2024年第2期10卷 647-680页

作者： Alexan.er n. Safron.v Obukhov In.titute of Atmospheric Physics Russian Academy of Sciences Moscow Russia

Chemical elemen.s in.space can.be syn.hesized by stellar n.clear reactors. Studyin. the dyn.mics of processes occurrin. in.the stars in.roduces a con.ept of the en.emble-averaged stellar reactor. For future in.erstellar mission., the terrestrial an. solar abun.an.es w.re compared w.th con.iderable n.mber of stars allocated in.the ~200 pc solar n.ighborhood. Accordin. to the value of the effective temperature, four stellar classes are distin.uished, for w.ich the correlation.coefficien.s an. stan.ard deviation.are calculated. The statemen. about the possibility of tran.ferrin. heavy elemen.s syn.hesized by stars over lon. distan.es in.space has been.completely refuted. There is n. immutability of the distribution.of elemen.s on.n.ighborin. stars an. in.the Solar System. It is show.0}that chemical elemen.s are main.y syn.hesized in.ide each stellar reactor. The theory of the buoyan.y of elemen.s is gen.ralized to stars. It has been.suggested that stars overheat due to a shift in.the parameters of n.clear processes occurrin. in.ide stars, w.ich leads to the syn.hesis of heavy elemen.s.

关键词： Stellar n.cleogen.sis Solar Abun.an.e En.emble-Averaged Stellar Reactor Stellar Abun.an.e In.erstellar Mission Habitability Dn.-Star

Time for a n.w.Paradigm in.On.ology? View.oin. of the Radiobiologist

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Open.Journ.l of Biophysics 2024年第1期14卷 11-55页

作者： Aleksey n. Shoutko Departmen. of Tran.plan.ation.an. Cells Techn.logies Russian Research Center of Radiology and Surgical Technologies Named after A. M. Granov Saint-Petersburg Russia

The curren. immun.on.ology artificially ign.res the con.ection.w.th lymphopoiesis, though is on.y its derivative. Hematopoietic stem cells (HSC) provide physiological regen.ration.of biomass of the host, fetus, an. malign.n. tumors, as w.ll, as the cells’ reparation.after sub-lethally in.urin. in.an. tissues an. their ren.w.l. HSC, especially of lymphoid lin.age, are the most vuln.rable of those, w.ich are respon.ible for viability of organ.sm. n.tural an. artificial deficits of HSC determin. agin., multi-organ. syn.romes an. death of the host, because their curren. proliferative resource (CPR) is in.ividually limited at birth, an. is spen.in. irreversibly durin. w.un.s’ healin., pregn.n.y, tumor grow.h, an. on. CPR, bein. an.in.egral value of the n.mber of stem cells alon. the len.th of their telomeres, is a “shagreen.skin., for w.ich the tumor competes w.th n.rmal tissues as a quasi-embryon.c favorite an. w.n.er, especially in.the fin.l period of a shorten.n. the life. The primary approach to can.er treatmen. must prioritize the preservation.of CPR remn.n.s, rather than.their destruction. in.order to temporarily halt the malign.n. process. The re-targetin. of HSC from tumors in.favor of n.rmal tissues is the immediate objective of competitive therapy, w.ich allow. for preservin. the rest of the CPR host’s resources, especially in.patien.s w.th advan.ed can.er. How.ver, the con.radictory an. in.ign.fican. practically, the dogma of an.itumor cellular immun.ty con.in.es to domin.te an. hin.er progress in.on.ology.

关键词： Lymphopoiesis Proliferatin. Resource Morphogen.sis Can.er-Fetus Reparation.Regen.ration Competitive Therapy

The Effect of a Mon.tomic Layer on.a Surface on.the Tran.ition.Radiation

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Journ.l of High En.rgy Physics, Gravitation.an. Cosmology 2024年第2期10卷 710-723页

作者： Alexan.er n. Safron.v Obukhov In.titute of Atmospheric Physics Russian Academy of Sciences Moscow Russia

The tran.ition.radiation.of a charged particle crossin. the in.erface of tw. media havin. a mon.tomic impurity layer is in.estigated. It is show.0}that at slidin. an.les of in.iden.e of a particle on.the boun.ary of the media, the tran.ition.radiation.is main.y determin.d by the properties of the surface layer. The possibility of usin. tran.ition.radiation.to study the surface of substan.es is discussed. In.addition. due to the hard radiation.presen. in.space, this research may be importan. for the use of light mon.atomic layers as a material for satellite an.en.as, “solar sails” an. cover layers in.a future space (in.erstellar) mission.

关键词： Relativistic Charged Particle Tran.ition.Radiation Mon.tomic Layer Spectral An.ular Distribution.of Radiation Slidin. An.le In.estigation.of Thin.Films In.erstellar Mission

Life Origin.in.the Milky w.y Galaxy: III. Spatial Distribution.of Overheated Stars in.the Solar n.ighborhood

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Journ.l of High En.rgy Physics, Gravitation.an. Cosmology 2024年第2期10卷 693-709页

作者： Alexan.er n. Safron.v Obukhov In.titute of Atmospheric Physics Russian Academy of Sciences Moscow Russia

A con.ept of en.emble averaged stellar reactors is developed to study the dyn.mics of processes occurrin. in.stars, allocated in.the ~200 pc solar n.ighborhood. Accordin. to the effective temperature value, four stellar classes are iden.ified, for w.ich the correlation.coefficien.s an. stan.ard deviation.are coun.ed. The theory of the buoyan.y terrestial elemen.s is gen.ralized to stellar systems. It w.s suggested that stars are over-heated due to the shift parameters of the n.clear processes occurrin. in.ide the stars, w.ich leads to the syn.hesis of tran.uran.um elemen.s un.il the achievemen. of a critical n.clear mass an. star explosion. The heavy tran.uran.um elemen.s sin. dow.0}ard an. are con.en.rated in.the stellar depth layers. The physical explan.tion.of the existen.e of the critical Chan.rasekhar star limit has been.offered. Based on.the spatial an.lysis of overheated stars, it w.s suggested that the w.thdraw.l of the stellar reactor from the equilibrium state is a con.equen.e of extragalactic compression.in.ide the galaxy arm due to the arm spirality (n.t to be con.used w.th the spirality of the galaxy itself).

关键词： Stellar n.cleogen.sis En.emble-Averaged Stellar Reactor Overheated Stars Chan.rasekhar Stellar Limit Arm Spirality

Telomeric Dn. breaks in.human.in.uced pluripoten. stem cells trigger ATR-mediated arrest an. telomerase-in.epen.en. telomere damage repair

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Journ.l of Molecular Cell Biology 2024年第3期16卷 46-60页

作者： Katrin. n.Estep John.w.Tobias Rafael J.Fern.n.ez Brin.ey M.Beveridge F.Brad John.on Departmen. of Pathology an. Laboratory Medicin. University of PennsylvaniaPhiladelphiaPA 19104USA Quan.iative Bioscien.es Merck&Co.Inc.West PointPA 19486USA Pen. Gen.mic An.lysis Core University of PennsylvaniaPhiladelphiaPA 19104USA

Although mechan.sms of telomere protection.are w.ll-defin.d in.differen.iated cells,how.stem cells sen.e an. respon. to telomere dysfun.tion.in.particular telomeric double-stran. breaks(DSBs),is poorly ***,w. report the Dn. damage sign.lin.,cell cycle,an. tran.criptome chan.es in.human.in.uced pluripoten. stem cells(iPSCs)in.respon.e to telomere-in.ern.l *** en.in.er human.iPSCs w.th an.in.ucible TRF1-FokI fusion.protein.to acutely in.uce DSBs at *** this model,w. demon.trate that TRF1-FokI DSBs activate an.ATR-depen.en. Dn. damage respon.e,w.ich leads to p53-in.epen.en. cell cycle arrest in.*** CRISPR–Cas9 to cripple the catalytic domain.of telomerase reverse tran.criptase,w. show.that telomerase is largely dispen.able for survival an. len.then.n. of TRF1-FokI-cleaved telomeres,w.ich in.tead are effectively repaired by robust homologous recombin.tion.HR).In.con.rast to HR-based telomere main.en.n.e in.mouse embryon.c stem cells,w.ere HR causes ZSCAn.-depen.en. exten.ion.of telomeres beyon. their in.tial len.ths,HR-based repair of telomeric breaks is sufficien. to main.ain.iPSC telomeres at a n.rmal len.th,w.ich is compatible w.th sustain.d survival of the cells over several days of TRF1-FokI *** fin.in.s suggest a previously un.ppreciated role for HR in.telomere main.en.n.e in.telomerase-positive iPSCs an. reveal distin.t iPSC-specific respon.es to targeted telomeric Dn. damage.

关键词： telomeres telomerase altern.tive len.then.n. of telomeres pluripoten. stem cells Dn. damage double-stran. breaks

Design.an. Developmen. of a Parabolic Trough Solar Air Heater for a Green.ouse Dryer

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Journ.l of Pow.r an. En.rgy En.in.erin. 2024年第9期12卷 1-18页

作者： Eric Kin.’ori Isaac n. Simate Departmen. of Mechan.cal En.in.erin. The University of Zambia Lusaka Zambia Departmen. of Agricultural En.in.erin. The University of Zambia Lusaka Zambia

Design.an. Developmen. of a Parabolic Trough Solar Air Heater (PTSAH) for a Green.ouse Dryer (GD) w.s don. to improve the dryer’s performan.e. The materials used for the fabrication.of the PTSAH in.luded galvan.zed sheets covered w.th alumin.um foil, an.absorber tube made of GI pipe pain.ed matt black to in.rease heat absorban.e at the focal lin., mild steel square tubes, shutter plyw.od, an. an.axial fan.to push air through the absorber tube. Key geometrical parameters used for the design.of the PTSAH w.re a rim an.le of 98 degrees, focal len.th of 0.2608 m, height of 0.3451 m, len.th of 2 m, an. an.aperture w.dth of 1.2 m. The PTSAH’s total aperture surface area w.s 2.4 m2, w.ile its absorber tube surface area w.s 0.1587 m2. The PTSAH w.s experimen.ally tested to establish its thermal performan.e. It w.s foun. that the ambien. air recorded an.average value of 31.1˚C an. that the air heater could in.rease the air temperature by 45.6˚C above ambien. w.th a thermal efficien.y of 5.3%. It can. therefore, be con.luded that the PTSAH can.sign.fican.ly improve the performan.e of a GD by supplyin. the GD w.th air at a higher temperature than.ambien..

关键词： Solar Air Heater Green.ouse Dryer Parabolic Trough Thermal Performan.e

Chebyshev polyn.mial-based Ritz method for thermal bucklin. an. free vibration.behaviors of metal foam beams

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Applied Mathematics an. Mechan.cs(En.lish Edition. 2024年第5期45卷 891-910页

作者： n.D.n.UYEn.T.n.n.UYEn Faculty of Civil En.in.erin. Ho Chi Minh City University of Technology and EducationHo Chi Minh City 71309Viet Nam Faculty of En.in.erin. an. Techn.logy Kien Giang UniversityChau Thanh 92000Viet Nam

This study presen.s the Chebyshev polyn.mials-based Ritz method to examin. the thermal bucklin. an. free vibration.characteristics of metal foam *** an.lyses in.lude three models for porosity distribution.an. tw. scen.rios for thermal *** material properties are assessed un.er tw. con.ition.,i.e.,temperature depen.en.e an. temperature *** theoretical framew.rk for the beams is based on.the higher-order shear deformation.theory,w.ich in.orporates shear deformation. w.th higher-order *** govern.n. equation. are established from the Lagran.e equation.,an. the beam displacemen. fields are approximated by the Chebyshev *** simulation. are performed to evaluate the effects of thermal load,slen.ern.ss,boun.ary con.ition.BC),an. porosity distribution.on.the bucklin. an. vibration.behaviors of metal foam *** fin.in.s highlight the sign.fican. in.luen.e of temperature-depen.en.(TD)material properties on.metal foam beams'bucklin. an. vibration.respon.es.

关键词： Ritz method Chebyshev fun.tion bucklin. vibration metal foam beam higher-order beam theory(HOBT)

A Review.of Biochemical Processes an. Techn.ques for Soil Stabilization.an. Resilien.e

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Advan.es in.Biological Chemistry 2024年第1期14卷 40-54页

作者： Jon.than.A. Metuge Zachary n. Sen.o Departmen. of Biological an. En.iron.en.al Scien.es Alabama A & M University Normal USA

Biochemical, chemical, an. mechan.cal, techn.ques have been.employed to en.an.e soil resilien.e for decades. w.ile the use of mechan.cal techn.ques requires tran.portin. huge amoun.s of soil materials, the cemen. used in.chemical techn.ques may lead to in.rease atmospheric carbon.dioxide. n.merous studies in.icate that biochemical techn.ques may be less expen.ive, cost effective, an. en.iron.en.ally frien.ly. Biopolymers an. en.ymes derived from microorgan.sms have been.suggested as biological en.an.ers in.stren.then.n. an. fortifyin. soils used for earthen.structures. Lime an. other treatmen. techn.ques used as biobased materials have been.show.0}to be less effective for stabilizin. soils. Here, w. review.biochemical processes an. techn.ques in.olved in.the in.eraction. of soil en.ymes, microorgan.sms, microbial extracellular polymeric substan.es, an. other biopolymers w.th soil particles, an. the challen.es an. strategies of their use as biobased materials for stabilizin. soils. This review.provides their impacts on.various soil properties an. the grow.h poten.ials of agricultural crops. .

关键词： Biochemical Earthen.Structures Soil Resilien.e Biopolymers Soil En.ymes Agriculture Microorgan.sms Extracellular Polymeric Substan.es