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Effects of early postn.tal gastric an. colon.c microbiota tran.plan.ation.on.piglet gut health

Journ.l of An.mal Scien.e an. Biotechn.logy 2024年第2期15卷 645-658页

作者： Christin. Larsen.Simon. Margaard Offersen.An.ers Brun.e Mattia Pirolo Soumya Kan.i kar Luca Guadabassi Thomas Thyman. Departmen. of Veterin.ry an. An.mal Scien.e University of CopenhagenDyrlagevej 681870 Frederiksberg CDenmark An.mal n.trition Wageningen Livestock ResearchWageningen University&Research1 De Elst6708 WageningenThe Netherlands

Backgroun. Diarrhea is a major cause of reduced growth an. mortality in.piglets durin. the sucklin. an. wean.n. periods an. poses a major threat to the global pig *** an. gut dysbiosis may in.part be preven.ed via improved early postn.tal microbial colon.zation.of the *** secure better postn.tal gut colon.zation.we hypothesized that tran.plan.ation.of colon.c or gastric con.en. from healthy don.rs to n.wborn.recipien.s would preven. diarrhea in.the recipien.s in.the post-wean.n. *** objective was to examin. the impact of tran.plan.in. colon.c or gastric con.en. on.health an. growth parameters an. paraclin.cal parameters in.recipien. sin.le-housed piglets exposed to a wean.n. tran.ition.an. challen.ed with en.erotoxigen.c Escherichia coli(ETEC).Methods Seven.y-two 1-day-old piglets were ran.omized to four groups:colon.c microbiota tran.plan.ation.CMT,n.18),colon.c con.en. filtrate tran.plan.ation.CcFT,n.18),gastric microbiota tran.plan.ation.GMT,n.18),or salin.(COn.n.18).In.culation. were given.on.d 2 an. 3 of life,an. all piglets were milk-fed un.il wean.n.(d 20)an. shortly after challen.ed with ETEC(d 24).We assessed growth,diarrhea prevalen.e,ETEC con.en.ration.organ.weight,blood parameters,small in.estin.l morphology an. histology,gut mucosal fun.tion.an. microbiota composition.an. *** Episodes of diarrhea were seen.in.all groups durin. both the milk-an. the solid-feedin. phase,possibly due to stress associated with sin.le ***,CcFT showed lower diarrhea prevalen.e on.d 27,28,an. 29 compared to COn.all Pn.e on.d 27(Pn. a differen.e in.beta diversity compared to COn.Pn. other paraclin.cal en.poin.s were similar across *** In.con.lusion.on.y CcFT reduced ETEC-related post-wean.n. ***,the protective effect was margin.l,suggestin. that higher doses,more effective modalities of admin.stration

关键词： Colon.c con.en. filtrate tran.plan.ation Colon.c microbiota tran.plan.ation Gastric microbiota tran.plan.ation Gut microbiota Mucosa n.on.tal Post-wean.n. diarrhea

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Microbiota–gut–brain.axis an. its therapeutic application. in.n.urodegen.rative diseases

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Sign.l Tran.duction.an. Targeted Therapy 2024年第3期9卷 945-997页

作者： Jian.Shen. Loh Wen.Qi Mak Li kar Stella Tan.Chu Xin.n. Hon. Hao Chan.Shiau Hueh Yeow Jhi Biau Foo Yon. Sze On. Chee Wun.How Kooi Yeon. Khaw School of Pharmacy Monash University MalaysiaJalan Lagoon Selatan47500 Bandar SunwaySelangorMalaysia School of Pharmacy Faculty of Health&Medical SciencesTaylor’s University1Jalan TaylorsSubang Jaya 47500 SelangorMalaysia Digital Health&Medical Advan.emen.s Taylor’s University1Jalan TaylorsSubang Jaya 47500 SelangorMalaysia School of Bioscien.es Faculty of Health&Medical SciencesTaylor’s University1Jalan TaylorsSubang Jaya 47500 SelangorMalaysia UCL School of Pharmacy University College London29-39 Brunswick SquareLondon WC1N 1AXUK

The human.gastroin.estin.l tract is populated with a diverse microbial *** vast gen.tic an. metabolic poten.ial of the gut microbiome un.erpin. its ubiquity in.n.arly every aspect of human.biology,in.ludin. health main.en.n.e,developmen.,agin.,an. *** adven. of n.w sequen.in. techn.logies an. culture-in.epen.en. methods has allowed researchers to move beyon. correlative studies toward mechan.stic exploration. to shed light on.microbiome–host *** has un.eiled the bidirection.l commun.cation.between.the gut microbiome an. the cen.ral n.rvous system,referred to as the“microbiota–gut–brain.axis”.The microbiota–gut–brain.axis represen.s an.importan. regulator of glial fun.tion.,makin. it an.action.ble target to ameliorate the developmen. an. progression.of n.urodegen.rative *** this review,we discuss the mechan.sms of the microbiota–gut–brain.axis in.n.urodegen.rative *** the gut microbiome provides essen.ial cues to microglia,astrocytes,an. oligoden.rocytes,we examin. the commun.cation. between.gut microbiota an. these glial cells durin. healthy states an. n.urodegen.rative ***,we discuss the mechan.sms of the microbiota–gut–brain.axis in.n.urodegen.rative diseases usin. a metabolite-cen.ric approach,while also examin.n. the role of gut microbiota-related n.urotran.mitters an. gut ***,we examin. the poten.ial of targetin. the in.estin.l barrier,blood–brain.barrier,men.n.es,an. peripheral immun. system to coun.eract glial dysfun.tion.in.***,we con.lude by assessin. the pre-clin.cal an. clin.cal eviden.e of probiotics,prebiotics,an. fecal microbiota tran.plan.ation.in.n.urodegen.rative diseases.A thorough comprehen.ion.of the microbiota–gut–brain.axis will foster the developmen. of effective therapeutic in.erven.ion. for the man.gemen. of n.urodegen.rative diseases.

关键词： degen.rative therapeutic diseases

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On.solubility an. supersolubility of some classes of fin.te groups

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Scien.e Chin. Mathematics 2009年第2期52卷 272-286页

作者： SHUM kar Pin. SKIBA Alexan.er n. Departmen. of Mathematics University of Hong Kong Departmen. of Mathematics Francisk Skorina Gomel State University

AbstractLet G be a fin.te group an. H a subgroup of G. Then.H is said to be S-permutable in.G if HP = PH for all Sylow subgroups P of G. Let H sG be the subgroup of H gen.rated by all those subgroups of H which are S-permutable in.G. Then.we say that H is S-embedded in.G if G has a n.rmal subgroup T an. an.S-permutable subgroup C such that T ∩ H ? H sG an. HT = C.Our main.result is the followin.Theorem AA group G is supersoluble if an. on.y if for every n.n.cyclic Sylow subgroup P of the gen.ralized Fittin. subgroup F*(G) of G, at least on. of the followin. holds: Every maximal subgroup of P is S-embedded in.G.Every cyclic subgroup H of P with prime order or order 4 (if P is a n.n.abelian.2-group an. H ? Z ∞ (G)) is S-embedded in.G.

关键词： S-permutable subgroups S-embedded subgroups saturated formation. gen.ralized Fittin. subgroups supersoluble groups 20D10 20D20 20D25

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Are all primary omen.al in.arcts truly idiopathic?Five case reports

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World Journ.l of Clin.cal Cases 2024年第24期12卷 5596-5603页

作者： Haldun.kar Dan.al Khabbazazar n.han.Acar Şebn.m karasu Halis Bağ Fevzi Cen.iz Osman.n.ri Dilek Departmen. of Gen.ral Surgery Katip Celebi University Ataturk Training and Research Hospitalİzmir 35150Türkiye Departmen. of Radiology İzmir Katip Celebi UniversitySchool of Medicineİzmir 35150Türkiye Departmen. of Surgery İzmir Katip Celebi UniversitySchool of Medicineİzmir 35150Türkiye

BACKGROUn. Idiopathic omen.al in.arction.IOI)is challen.in. to diagn.se due to its low in.iden.e an. vague *** differen.ial diagn.sis also poses difficulties because it can.mimic man. in.ra-abdomin.l organ.*** hypercoagulability an. thrombosis are amon. the causes of omen.al in.arction.ven.us thromboembolism scan.in. is rarely performed as an.etiological *** SUMMARY The medical records of the 5 cases,who had the diagn.sis of IOI by computed tomography,were *** majority of the patien.s were male(n.4,80%)an. the mean.age was 31 years(ran.e:21-38).The patien.s had n. previous abdomin.l surgery or a history of an. chron.c *** main.complain. of all patien.s was persisten. abdomin.l *** in.arction.was detected in.all patien.s with con.rast-en.an.ed computed *** treatmen. was in.tially preferred in.all patien.s,but it failed in.1 patien.(20%).After discharge,all patien.s were referred to the hematology departmen. for thrombophilia *** 1 patien. applied for thrombophilia screen.n. an. was homozygous for methylen.tetrahydrofolate reductase(A1298C mutation.an. heterozygous for a factor V Leiden.*** IOI should be con.idered in.the differen.ial diagn.sis in.patien.s presen.in. with progressive an./or persisten. right side abdomin.l *** risk factors such as hypercoagulability in.patien.s with IOI is also importan. in.preven.in. future con.ition. related to ven.us thromboembolism.

关键词： Omen.al in.arction Acute abdomin.l pain Thrombophilia screen.n. Factor V Leiden Methylen.tetrahydrofolate reductase Case report

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Defin.n. min.mal in.asive surgical therapy for ben.gn.prostatic obstruction.surgery: Perspectives from a global kn.wledge, attitude, an. practice survey

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Asian.Journ.l of Urology 2024年第1期11卷 55-64页

作者： Bryan.Kwun.Chun. Chen. Steffi kar-Kei Yuen.Dan.ele Castellan. Marcelo Lan.er Wroclawski Hon.da Zhao Mallikarjun. Chiruvella Wei-Jin.Chua Ho-Yee Tion. Yiloren.Tan.dir Jean.de la Rosette En.ique Rijo Vin.en. Misrai Amy Krambeck Dean.S.Elterman.Bhaskar K.Soman. Jeremy Yuen.Chun.Teoh Vin.et Gauhar Departmen. of Surgery United Christian HospitalHong KongChina S.H.Ho Urology Cen.re Department of SurgeryPrince of Wales HospitalThe Chinese University of Hong KongHong KongChina Departmen. of Urology University Hospital“Ospedali Riuniti”and Polytechnic University of Marche RegionAnconaItaly Hospital Israelita Albert Ein.tein Sao PauloSPBrazil BP—A Ben.ficen.ia Portuguesa de Sao Paulo Sao PauloSPBrazil Faculdade de Medicin. do ABC Santo AndreSPBrazil Departmen. of Urology Asian Institute of Nephrology and UrologyHyderabadTGIndia Departmen. of Urology National University HospitalSingapore Departmen. of Urology Marmara University School of MedicineIstanbulTurkey Departmen. of Urology Medipol Mega University HospitalIstanbul Medipol UniversityIstanbulTurkey Departmen. of Urology Hospital Quiron BarcelonaBarcelonaSpain Departmen. of Urology Clinique PasteurToulouseFrance Departmen. of Urology Indiana University School of MedicineIndianapolisINUSA Division.of Urology Department of SurgeryUniversity Health NetworkUniversity of TorontoTorontoCanada Departmen. of Urology University Hospital Southampton NHS TrustSouthamptonUK Departmen. of Urology Ng Teng Fong General HospitalNUHSSingapore

Objective:To scrutin.ze the defin.tion. of min.mal in.asive surgical therapy(MIST)an. to in.estigate urologists’kn.wledge,attitudes,an. practices for ben.gn.prostatic obstruction.***:A 36-item survey was developed with a Delphi *** on.defin.tion. of MIST an. attitudes an. practices of ben.gn.prostatic obstruction.surgeries were *** were in.ited globally to complete the on.in. *** was achieved when.more than.or equal to 70%respon.es were“agree or stron.ly agree”an. less than.or equal to 15%respon.es were“disagree or stron.ly disagree”(con.en.us agree),or when.more than.or equal to 70%respon.es were“disagree or stron.ly disagree”an. less than.or equal to 15%respon.es were“agree or stron.ly agree”(con.en.us disagree).Results:The top three qualities for defin.n. MIST were min.mal blood loss(n.466,80.3%),fast post-operative recovery(n.431,74.3%),an. short hospital stay(n.425,73.3%).The top three surgeries that were regarded as MIST were Urolift®(n.361,62.2%),Rezum®(n.351,60.5%),an. en.oscopic en.cleation.of the prostate(EEP)(n.332,57.2%).Con.en.us in.the kn.wledge section.was achieved for the superiority of Urolift®,Rezum®,an. iTIn.®over tran.urethral resection.of the prostate with regard to blood loss,recovery,day surgery feasibility,an. post-operative *** in.the attitudes section.was achieved for the superiority of Urolift®,Rezum®,an. iTIn.®over tran.urethral resection.of the prostate with regard to blood loss,recovery,an. day surgery *** on.both section. was achieved for EEP as the option.with the better symptoms an. flow improvemen.,lower retreatmen. rate,an. better suitable for prostate more than.80 ***:Min.mal blood loss,fast post-operative recovery,an. short hospital stay were the most importan. qualities for defin.n. ***®,Rezum®,an. EEP were regarded as MIST by most urologists.

关键词： Ben.gn.rostate hyperplasia Min.malin.asive surgical therapy Surgery Bladderoutlet obstruction

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Effect of Algae on.Melon.Cucumis melo *** ***)Growth an. Developmen. un.er Drought-Stress Con.ition.

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Phyton.In.ern.tion.l Journ.l of Experimen.al Botan. 2023年第11期92卷 3177-3193页

作者： M.Zeki karİPÇİn.Behcetİn.L Departmen. of Horticulture Faculty of AgricultureSiirt UniversitySiirt56100Türkiye Departmen. of Agricultural Biotechn.logy Faculty of Agriculture Siirt UniversitySiirt56100Türkiye

Due to climate chan.e,it is n.cessary to develop plan. varieties that are resilien. to climate con.ition. an. resistan. to abiotic an. biotic *** use of microalgae,which are microorgan.sms that con.ain.carbohydrates,protein.,lipids,an. vitamin.,again.t drought toleran.e is a n.w *** aim of the curren. study was to determin. the drought-related mechan.sms in.the con.mon.melon.gen.type an. develop drought-toleran. melon.***,physiological,pomological,an. molecular an.lyses were carried out on.the algae-treated *** has been.determin.d that commercial algae application.provides the best results in.leaf temperature,leaf relative water con.en.s(LRWC),plan. height,fruit len.th,fruit diameter,an. yield,while Cag Cag(a special river in.the region.stream algae application.gives better results in.main.stem *** was determin.d that the n.mber of n.des in.the con.rol(without algae)plots was higher than.in.the other two *** an. LRWC an. plan. height values of gen.type 7 were the best values amon. other *** leaf temperature measuremen. was lower on.gen.type 9 than.on.the other *** the highest fruit len.th value was measured in.gen.type 1,gen.type 8 was superior in.the main.stem diameter,fruit diameter,an. the n.mber of n.des amon. the remain.n. plan. *** terms of yield,it was determin.d that the in.eraction.between.gen.type 2 an. the commercial algae resulted in.the best *** addition.the results of the gen.tic evaluation.revealed that the materials used were n.t gen.tically distan. from each other an. more detailed gen.tic evaluation. are *** molecular kin.hip an.lysis revealed that the gen.types used in.the study were divided in.o three distin.t groups,with in.ividuals within.each group exhibitin. a high degree of relatedn.ss to on. *** a result of the study,it was foun. that the application.of microalgae had sign.fican. effects on.improvin. the drought toleran.e

关键词： Drought algae molecular taxon.my Cucumis melo subsp.agrestis var.con.mon

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Immun.prophylactic poten.ial of filarial glutathion.-s-tran.ferase in.lymphatic filariaisis

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Asian.Pacific Journ.l of Tropical Medicin. 2011年第3期4卷 185-191页

作者： Madhusmita Bal Man.al n.Achary KG Das MK kar SK Division.of Immun.logy Regional Medical Research Centre(Indian Council of Medical Research) ChandrasekharpurBhubaneswar-751023India

Objective:To elucidates the immun.prophylactic poten.ial of glutathion.s-tran.ferase(GST) from cattle filarial parasite Setaria digitata(***) again.t lymphatic ***: GST was purified through affin.ty chromatography(SdGST) an. chacterized by SDS-PAGE an. n.n.-LC MS/MS *** isotypes to SdGST were measured by *** depen.an. cellular cytotoxicity(ADCC) was performed in.vitro usin. sera from immun.zed an.mals an. immun. in.ividuals.T-cell proliferation.an. cytokin. respon.e to SdGST in.differen. groups of filariasis were *** poten.ial of SdGST was evaluate in.an.mal ***:SdGST exhibited 30-fold en.an.emen. of en.yme activity over crude parasitic *** was foun. to be 26 kDa by *** LC-MS/MS an.lysis followed by blast search showed 100%homology with Dirqfilaria immitis(***) an. on.y 43%with Homo sapien.(***).Immun.blottin. an.lysis showed putatively immun. in.ividuals carry sign.fican. level of an.ibodies to SdGST as compared with *** sera an. sera en.emic n.rmal could n.utralize the en.ymatic activity of SdGST an. in.ucin. in.vitro cytotoxicity of *** blood mon.n.clear cells(PBMC) from en.emic n.rmals upon.stimulation.with SdGST showed a mixed type of Th1/Th2 *** immun.zation.clear microfilariae from circulation.in.*** implan.ed ***:The heterologous GST could be poten.ially developed as a vaccin. can.idate again.t lymphatic filarial parasite.

关键词： Glutathion.-s-tran.ferase Setaria digitata Lymphatic filariasis

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Gen.tic diversity of PfEMP1-DBL 1-α an. its association.with severe malaria in.a hyperen.emic state of In.ia

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Asian.Pacific Journ.l of Tropical Medicin. 2010年第7期3卷 505-509页

作者： Ron.aly Rout Gun.n.dhi Dhan.adamajhi Biran.hi n.Mohapatra Shan.an. K kar Man.ran.an.Ran.it Region.l Medical Research Cen.re(ICMR) Bhubaneswar-751023Orissa.India SCB Medical College & Hospital.Cuttack-753007 Orissa.India Region.l Medical Research Cen.re(ICMR).Bhuban.swar-751023 Orissa.India

Objective:To fin. out the exten. of duffy-bin.in.-like(DBL) a gen. diversity an. the resettin. poten.ial of the parasite population.in.association.with severe ***:Gen.typin. of DBLαdomain.was don. by PCR usin. three sets of primers(FR,F1R2 an. F2R2) an. the rosettin. frequen.y was assessed by parasite culture followed by ethidium bromide stain.n. an. visualization.un.er a fluorescen. ***:The sign.fican. association.of high parasite den.ity with severe malaria an. the positive correlation.between.rosettin. frequen.y an. parasite den.ity in.vivo(P = 0.613,Pn. havin. multiple fragmen.s of F2R2 region.an.’b’varian. of FR region.of DBL 1-αshowed in.reased rosettin. frequen.y an. supported the strain.specific association.of disease severity. Con.lusion.:The fin.in.s suggest that rosettin. mediated higher parasitemia might have con.ributed to the developmen. of severe *** the rosettin. domain.of Plasmodium falciparum erythrocyte membran. protein.1(HEMP1),the DBL a bin.s to multiple host receptors; the sign.fican. association.of multiple fragmen.s of F2R2 region.with severe malaria suggests several receptor-ligan. in.eraction. as the possible mechan.sms of ***, the high percen.age distribution.of smaller fragmen.s with mild malaria suggests the lack of adequate rosettin. epitopes that might have con.ributed to low rosettin. frequen.y in.mild malaria.

关键词： Plasmodium falciparum Rosettin. Parasite den.ity DBL 1-α Severe malaria

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The con.truction.of orthodox super rpp semigroups

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Scien.e Chin. Mathematics 2004年第4期47卷 552-565页

作者： He Yon. Guo Yuqi kar Pin. Shum School of Computer Scien.e Hunan University of Science&TechnologyXiangtan 411201China Departmen. of Mathematics Southwest Normal UniversityChongqing 400715China Departmen. of Mathematics Soochow UniversitySuzhou 215000China Faculty of Scien.e The Chinese University of Hong KongShatinN.T.Hong KongChina

We defin. orthodox super rpp semigroups an. study their semilattice decomposition.. Stan.ard represen.ation.theorem of orthodox super rpp semigroups whose subban. of idempoten.s is in.the varieties of ban.s described ... 详细信息

关键词： orthodox super rpp semigroup, ban.-like exten.ion. left can.ellative plan., semilattice decomposition. stan.ard represen.ation.

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Ion.c liquid/tetraglyme hybrid Mg[TFSI]_2 electrolytes for rechargeable Mg batteries

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Green.En.rgy & En.iron.en. 2019年第2期4卷 146-153页

作者： Zhen. Ma Maria Forsyth Douglas R.MacFarlan. Mega kar School of Chemistry Faculty of Science Monash University ARC Cen.re of Excellen.e for Electromaterials Scien.e IFM – Institute for Frontier Materials Deakin University

The electrochemical reversibility of Mg in.hybrid electrolytes based on.mixtures of ion.c liquid an. glyme based organ.c solven.s was in.estigated for application. in.rechargeable magn.sium batteries(RMBs). The electrolytes demon.trate reversible reduction.an. oxidation.of Mg on.y after bein. pre-treated with the dehydratin. agen., magn.sium borohydride, Mg[BH_4]_2, highlightin. the importan.e of removin. water in.Mg based electrolytes. The addition.magn.sium di[bis(trifluoromethan.sulfon.l)imide](Mg[TFSI]_2)(0.3 M) to n.butyl-n.methyl-pyrrolidin.um bis(trifluoromethan.sulfon.l)imide [C4 mpyr][TFSI]/tetraglyme at a mole ratio of 1:2 showed stable CV cyclin. over almost 300 cycles while scan.in. electron.microscopy(SEM) an. X-ray diffraction.XRD) con.irmed Mg deposition. showin. n.n.den.ritic morphology an. a well-align.d growth. Further thermogravimetric an.lysis(TGA) demon.trated a mass reten.ion.of 79% at 250℃ for this electrolyte suggestin. that the presen.e of the ion.c liquid in.reases thermal stability substan.ially makin. these hybrid electrolytes compatible for RMBs.

关键词： Mg[TFSI]2 Ion.c liquids Tetraglyme Rechargeable Mg battery Mg[BH4]2 dehydrate reagen.

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