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铸锻热（热处理实践） 1993年第2期 34-37页

作者： wol.,IM

The Matter of somerset Maugham:A World With Properties

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宁夏大学学报（人文社会科学版） 1997年第3期19卷 102-106页

作者： HowardR.wol

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The modulation of radiation-induced cell death by genistein in K562 cells:Activation of thymidine kinase 1

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Cell Research 2004年第4期14卷 295-302页

作者： Min Ho JEONG,Young Hee JIN,Eun Young KANG,wol.soon JO,Hwan Tae PARK,Jae Dong LEE,Yeo Jin YOO,soo Jin JEONG Research supporting Center for Medical science (BK21 program) Dong-A University College of Medicine Busan Korea Research supporting Center for Medical science (BK21 program) Dong-A University College of Medicine Busan Korea Research supporting Center for Medical science (BK21 program) Dong-A University College of Medicine Busan Korea Research supporting Center for Medical science (BK21 program) Dong-A University College of Medicine Busan Korea Research supporting Center for Medical science (BK21 program) Dong-A University College of Medicine Busan Korea Department of Microbiology Pusan National University Busan Korea Research supporting Center for Medical science (BK21 program) Dong-A University College of Medicine Busan Korea Research supporting Center for Medical science (BK21 program) Dong-A University College of Medicine Busan Korea Virus Tumor Biology section Laboratory of Cellular Oncology Center for Cancer Research National Cancer Institutes National Institute of Health Bethesda MD 20892 UsA

Ionizing radiation is one of the most effective tools in cancer therapy. In a previous study, we reported that protein tyrosine kinase (PTK) inhibitors modulate the radiation responses in the human chronic myelogenous leukemia (CML) cell line K562. The receptor tyrosine kinase inhibitor, genistein, delayed radiation-induced cell death, while non-recepter tyrosine kinase inhibitor, herbimycin A (HMA) enhances radiation-induced apoptosis. In this study, we focused on the modulation of radiation-induced cell death by genistein and performed PCR-select suppression subtractive hybridization (ssH) to understand its molecular mechanism. We identified human thymidine kinase 1 (TK1), which is cell cycle regulatory gene and confirmed expression of TK1 mRNA by Northern blot analysis. Expression of TKl mRNA and TK1 enzymatic activity were parallel in their increase and decrease. TK1 is involved in G1-s phase transition of cell cycle progression. In cell cycle analysis, we showed that radiation induced G2 arrest in K

关键词： K562 radiation cell death genistein thymidine kinase 1 cell cycle.

Jeju seaweeds suppress lipopolysaccharide-stimulated proinflammatory response in RAW 264.7 murine macrophages

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Asian Pacific Journal of Tropical Biomedicine 2014年第7期4卷 529-537页

作者： Eun-Jin Yang Ji-Young Moon sang suk Kim Kyong-wol.Yang Wook Jae Lee Nam Ho Lee Chang-Gu Hyun Cosmetic science Center Department of ChemistryJeju National University Jeju Technopark Ara-1-dongJeju-siJeju 690-121.Korea Citrus Research station National Institute of Horticultural & Herbal ScienceRDAJeju 699-946.Korea Jeju Love Co. Ltd.542-5 Haengwon-ri.Gujwa-eupJeju 695-975.Korea LINC Agency Jeju National University

Objective:To investigate the anti-inflammatory effects of Jeju seaweeds on macrophage RAW264.7 cells under lipopolysaccharide(LPs)***:Ethyl acetate fractions were prepared from five different types of Jeju seaweeds,Dictyopteris divaricata(***),Dictyopteris prolifera(***),Prioutis cornea(***,Grateloupia laceolata(G,lanceolate,and Cralcloupia filicina(***)They were screened for inhibitory effects on proinflammatory mediators and cytokines such as nitric oxide(NO),prostaglandin E,,tumor necrosis factor-a(TNF-a),and interleukin-6(11.-6).Results:Our results revealed that ***,***,***,***,and *** potently inhibited ***-stimulaled NO production(IC_(50),values were 18.0,38.36,38.43,32.81 and 37.14μg/mL,respectively).Consistent with these findings,***,***,***,and *** also reduced the IPs-induced and prostaglandin E,production in a concentration-dependent ***,they suppressed the expression of inducible NO synthase and cyclooxygenase-2 at the protein level in a dose-dependent manner in the RAW264.7 cells,as detennined by western *** addition,the levels of TNF-a and IL-6,released into the medium,were also reduced by ***,***,***,G,lanceolata,and *** in a dose-dependent manner(IC_(50)values for TNF-a were 16.11,28.21,84.27,45.52 and74.75μg/mL,respectively;IC_(50),values for IL-6 were 37.35,80.08,103.28,62.53 and 84.28μg/mL,respectively).The total phlorotannin content was measured by the Folin-Ciocalteu method and expressed as phloroglucinol *** content was 92.0μg/mg for ***,151.8μg/mg for ***,57.2μg/mg for ***,53.0 pg/mg for ***,and 40.2μg/mg for ***:Thus,these findings suggest that Jeju seaweed extracts have potential therapeutic applications for inflammatory responses.

关键词： Nitrie oxide Inlerleukin-6 Prostaglandin E_2 Tumor necrosis factor-α seaweeds Proinflammatory mediators

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橡胶用炭黑的现状及全球性发展趋势

轮胎研究与开发 1991年第3期17卷 1-5页

作者： wol.H 梁铮

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防止脱轨的新策略

国外铁道车辆 2001年第2期38卷 34-39页

作者： GaryP.wol.孔军宋国文

介绍了防止脱轨的有效策略 ,并着重对脱轨原因分析方法以及技术进步对脱轨原因调查所起的积极帮助作用等进行了阐述。运用实践证明 ,早期发现是防止脱轨的关键 ,而一个具有系统性的总体方案 ,以及具有责任心的专业人员或专业队伍。

关键词：脱轨防止策略铁路原因早期发现

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凿山建屋

家居主张 2012年第10期 48-50页

作者： seArch &CMA Michel Harris wol.rich 杨捷 Jay Rostin

这是一处堪称神奇的所在。我们首先是被其坐落的位置所吸引。整个建筑凹陷在山坡里,乍看仿佛在一个巨大的弹坑中构建出了只有童话里才有的住所。这是瑞士阿尔卑斯山区一座山村中的场景,这里向以矿泉水和温泉浴闻名于世,直到有一天来了... 详细信息

这是一处堪称神奇的所在。我们首先是被其坐落的位置所吸引。整个建筑凹陷在山坡里,乍看仿佛在一个巨大的弹坑中构建出了只有童话里才有的住所。这是瑞士阿尔卑斯山区一座山村中的场景,这里向以矿泉水和温泉浴闻名于世,直到有一天来了几位想象力极为活跃的年轻建筑设计师,他们被这里漫山遍野绿色的植被和远处阿尔卑斯山皑皑的雪山所陶醉,既不想破坏了山景,也不愿就此离去。

关键词：建筑山坡场景凹陷构想建构开凿住所瑞士阿尔卑斯山原木

源于克雷伯氏菌Klebsiella sp. AC-11的3株噬菌体的生物学特性

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海洋学报 2011年第4期33卷 147-154页

作者：刘斌 JOsT Gunter sCHMIEL Juliane wol. Arite 黄翔玲谷力王玉桥叶德赞国家海洋局第三海洋研究所福建厦门361005 国家海洋局海洋生物遗传资源重点实验室福建厦门361005 莱布尼兹波罗的海研究所德国罗斯托克D-18119 罗斯托克大学分子生理与生物技术实验室德国罗斯托克D-18051

从国家海洋局第三海洋研究所海水养殖池中分离得到一株细菌AC-11,16srDNA序列分析表明其与肺炎克雷伯氏菌肺炎亚种(Klebsiella pneumoniaesub sp. pneumoniae)具有最高的序列同源性达99.78%。以此菌株为宿主菌,于2008年11月采用双层平... 详细信息

从国家海洋局第三海洋研究所海水养殖池中分离得到一株细菌AC-11,16srDNA序列分析表明其与肺炎克雷伯氏菌肺炎亚种(Klebsiella pneumoniaesub sp. pneumoniae)具有最高的序列同源性达99.78%。以此菌株为宿主菌,于2008年11月采用双层平板法分离得到3株裂解性噬菌体KP1,KP2和KP3,其中KP2分离自同一海水养殖池,另外2株则来源于厦门筼筜湖海水样品。分别对宿主菌及噬菌体进行了电镜形态观察,并对噬菌体进行了BglⅡ和EcoRⅤ两种酶的限制性酶切分析,发现它们均属于长尾噬菌体科(siphoviridae),但具有不同的酶切图谱;同时测定了3株噬菌体的最佳感染复数、一步生长曲线及对温度、pH、紫外线、乙醚和氯仿等理化因素的敏感性等生理特性。实验结果表明3株噬菌体具有不同的生物学特性,为不同株型。本研究丰富了对噬菌体多样性的认识,并为进一步应用噬菌体诊断和治疗潜在的由肺炎克雷伯氏菌引发的疾病及细菌分型等研究提供了理论基础。

关键词：肺炎克雷伯氏菌肺炎亚种(Klebsiella pneumoniae sub sp. pneumoniae) 噬菌体电子显微镜观察生物学特性

Decrease of memory retention in a parasitic wasp： an effect of host manipulation by wol.achia？

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Insect science 2017年第4期24卷 569-583页

作者： Hossein Kishani Farahani Ahmad Ashouri seyed Hossein Goldansaz Martin s. shapiro Jean-sebastien Pierre Joan van Baaren Faculty of Agriculture and Natural Resources Department of Plant Protection University of Tehran Karaj Iran Department of Psy- chology California State University Fresno USA UMR-CNRs 6553 EcoBio University of Rennes 1 Avenue du General Leclerc Campus de Beaulieu 35042 Rennes Cedex France

several factors, such as cold exposure, aging, the number of experiences and viral infection, have been shown to affect learning ability in different organisms. wol. bachia has been found worldwide as an arthropod parasite/mutualist symbiont in a wide range of species, including insects. Differing effects have been identified on physiology and behavior by wol.achia. However, the effect of wol.achia infection on the learning ability of their host had never previously been studied. The current study carried out to compare learning ability and memory duration in 2 strains of the parasitoid Trichogramma brassicae： 1 uninfected and I infected by wol.achia. Both strains were able to associate the novel odors with the reward of an oviposition into a host egg. However, the percentage of females that responded to the experimental design and displayed an ability to learn in these conditions was higher in the uninfected strain. Memory duration was longer in uninfected wasps （23.8 and 21.4 h after conditioning with peppermint and lemon, respectively） than in infected wasps （18.9 and 16.2 h after conditioning with peppermint and lemon, respec- tively）. Memory retention increased in response to the number of conditioning sessions in both strains, but memory retention was always shorter in the infected wasps than in the uninfected ones. wol.achia infection may select for reduced memory retention because shorter memory induces infected wasps to disperse in new environments and avoid compe- tition with uninfected wasps by forgetting cues related to previously visited environments, thus increasing transmission of wol.achia in new environments.

关键词： associative learning memory duration spacing learning Trichgramma bras-sicae wol.achia infection

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纺织工业4.0时代--人的地位及影响因素

国际纺织导报 2018年第4期46卷 54-56页

作者： s.Olbert-Bock J.Pauli W.Merx J.Lemm Y.Gloy 王宏球(译) 于俊荣(校) 圣加仑高等专业学校瑞士亚琛工业大学德国不详

长期以来,数字化、工业4.0(I 4.0)及未来劳动力在日常生活中占据着不可或缺的地位。因此,人们针对企业的发展现状及所谓的"准备就绪"开展了大量的研究。迄今为止,对I 4.0的研究主要集中于技术层面,而很少从工作环境利益角度进行研究。... 详细信息

长期以来,数字化、工业4.0(I 4.0)及未来劳动力在日常生活中占据着不可或缺的地位。因此,人们针对企业的发展现状及所谓的"准备就绪"开展了大量的研究。迄今为止,对I 4.0的研究主要集中于技术层面,而很少从工作环境利益角度进行研究。对德国、奥地利和瑞士纺织业的35家企业进行在线研究,结果表明:多达64%的参与者来自企业管理层(高层和中、下层管理水平的参与者占相同比例),其中近34%的参与者来自大型企业。

关键词：纺织业工业4.0 劳动力企业