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Note on Lower Triassic Gondolelloid Conodont Rediversifications with Emphasis on the Spathian Recovery

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Journal of Earth Science 2024年第4期35卷 1236-1242页

作者： Ali murat Kilic department of Geological Engineering Faculty of EngineeringBalikesir UniversityBalikesir99100Turkey

Conodonts,as a biotic group,next to ammonoids,pollen and spores,crustaceans and vertebrates,provide proxy clues for environment and age assessments of the rocks in which they *** are widely used for Triassic marine ***,there are various discussions about their multielement taxonomy and evolutionary lineages(e.g.,generation,speciation).Although first studies reported that most Triassic conodont species were unimembrate,studies carried out in the following years maintained that all Triassic conodonts were *** statistical reconstructions of a number of Triassic apparatuses were attempted,the discovery of fused clusters and natural assemblages has subsequently demonstrated that Triassic conodonts are indeed multimembrate,and all of the elements exist together in the same *** present paper aims to clarify the evolutionary relationship and array of some Lower Triassic *** dagisi *** described.

关键词： Triassic Spathian conodont Columbitella Siberia environmental geology

Effect of a cervical collar on optic nerve sheath diameter in trauma patients

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World Journal of Emergency Medicine 2024年第2期15卷 126-130页

作者： Mümin murat Yazici Ozcan Yavasi department of Emergency Medicine Recep Tayyip Erdogan University Training and Research HospitalRize 53020Türkiye

BACKGROUNd:As advocated in advanced trauma life support and prehospital trauma life support protocols,cervical immobilization is applied until cervical spine injury is *** study aimed to show the difference in optic nerve sheath diameter(ONSd)between patients with and without a cervical collar using computed tomography(CT).METHOdS:This was a single-center,retrospective study examining trauma patients who presented to the emergency department between January 1,2021,and december 31,*** ONSd on brain CT of the trauma patients was measured and analyzed to determine whether there was a difference between the ONSd with and without the cervical ***:The study population consisted of 169 *** CT imaging of patients with(n=66)and without(n=103)cervical collars,the mean ONSd in the axial plane were 5.43±0.50 mm and 5.04±0.46 mm respectively for the right eye and 5.50±0.52 mm and 5.11±0.46 mm respectively for the left *** results revealed an association between the presence of a cervical collar and the mean ONSd,which was statistically significant(Pd left ***:A cervical collar may be associated with increased *** effect of this increase in the ONSd on clinical outcomes needs to be investigated,and the actual need for cervical collar in the emergency department should be evaluated on a case-by-case basis.

关键词： Optic nerve sheath diameter Computed tomography Trauma Emergency medicine

Effects of pressure relief holes on coal burst:Insights from true-triaxial unloading tests

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3378-3394页

作者： Fuqiang Ren murat Karakus Giang Nguyen Thomas Bruning School of Civil Engineering University of Science and Technology LiaoningAnshan114051China Mining and Petroleum Engineering The University of AdelaideAdelaideSouth Australia5005Australia State Key Laboratory for Geomechanics&deep Underground Engineering China University of Mining and TechnologyBeijing100083China School of Architecture and Civil Engineering The University of AdelaideSouth Australia5005Australia

drilling pressure relief is one of the methods to reduce the risk of coal bursts in deep ***,the effect of the drill hole orientations has not been studied well enough to understand their impact on the burst failure *** this study,we investigated two designs of drill hole *** first design includes drill holes located on the upper free face of the rectangular samples and labelled as upper hole(UH)and centre hole(CH)e the long axes of the drill holes are aligned with minor principal stress,s3,*** second design includes drill holes at the top(TH)and the side(SH)of the rectangular samples in which the long axes of the drill holes are aligned with the maximum,s1,and intermediate principal stress,s2,directions,*** coal samples with the proposed drill hole orientations were subjected to the true-triaxial unloading coal burst *** results show that the drill holes reduce the risk of coal ***,we found that the intensity of coal burst was significantly reduced with the SH-type,followed by the *** also observed that the coal burst intensity is reduced better for the CH,UH,TH,and SH-type drilling ***,it was found that the orientations of drill holes have little influence on the failure mode(splitting).The acoustic emission(AE)activities for coal with drill holes noticeably decreased,especially for the UH and CH *** drill holes reduced the upper limit of the AE entropy(chaos of microcracks generation).However,regarding reducing the coal burst risk,the TH and SH are less effective than UH and CH.

关键词： Coal burst Triaxial unloading drilling orientation Ejection characteristic Acoustic emission(AE)

Immunotherapy in gastric cancer with liver metastasis:Challenges and opportunities

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1513-1516页

作者： murat Bardakçi Yakup Ergun department of Medical Oncology Diyarbakır Gazi Yasargil Training and Research HospitalDiyarbakir 021000KayapinarTürkiye department of Medical Oncology Antalya City HospitalAntalya 07080Türkiye

In this editorial,we review the article by Liu et al published in the World Journal of Gastrointestinal Surgery investigating the efficacy and safety of immunotherapy in patients with gastric cancer(GC)and liver ***,the fifth most com-monly diagnosed malignancy worldwide,presents a significant challenge due to its multifactorial etiology and a grim prognosis for unresectable or recurrent *** advent of immune checkpoint inhibitors(ICIs)has revolutionized oncology;yet liver metastasis has been associated with reduced response rates,progression-free survival,and overall survival in various *** Che-ckMate-649 and KEYNOTE-859 trials demonstrated promising results with ICIs in advanced GC,particularly in patients with liver ***,a meta-analysis of liver metastatic solid tumors revealed worse outcomes with ICIs,high-lighting the need for further *** combined therapies,including ICIs with local treatments,show promise in improving outcomes,the nuanced landscape of ICIs in liver metastatic GC necessitates continued research for robust *** current contradictions in the literature underscore the impor-tance of cautious interpretation and the exploration of tailored approaches to enhance clinical efficacy in this challenging patient population.

关键词： Gastric cancer Liver metastasis Immunotherapy Immune checkpoint in-hibitors Transarterial chemoembolization Tumor microenvironment

Activated carbon derived from radiation-processed durian shell for energy storage application

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Carbon Resources Conversion 2024年第2期7卷 27-37页

作者： Phonpimon Numee Tanagorn Sangtawesin murat Yilmaz Kotchaphan Kanjana Functional Materials and Nanotechnology Center of Excellence Walailak UniversityTha SalaNakhon Si Thammarat 80160Thailand Thailand Institute of Nuclear Technology OngkharakNakhon Nayok 26120Thailand department of Chemistry and Chemical Processing Technologies Bahçe Vocational SchoolOsmaniye Korkut Ata UniversityOsmaniye 80000Türkiye department of Chemistry School of ScienceWalailak UniversityTha SalaNakhon Si Thammarat 80160Thailand

A lignocellulosic biomass,durian shell,modified by radiolytic oxidizing species from gamma and electron beam irradiations,has been used as a starting material for activated carbon(AC)*** hydrothermal carbonization with ZnCl_(2)/FeCl_(3)and physical activation were employed in *** physicochemical and energy storage properties of the graphitic carbons were investigated using Field Emission Scanning Electron Microscope(FESEM),N_(2)adsorption-desorption,Brunauer-Emmett-Teller(BET),Fourier Transform Infrared Spectroscopy(FTIR),X-ray diffraction(XRd),Raman spectroscopy,Cyclic Voltammetry(CV),Galvanostatic Charge-discharge(GCd)and Electrochemical Impedance Spectroscopy(EIS).Biomass modification by radiolytic oxidizing species aided in improving the energy storage properties of the resultant ACs without significantly changing the textural *** radiation type played an important role on the surface functional groups,basal plane,and pore structures of the graphitic *** energy storage mechanism was based on a combination of EdLC and pseudo capacitances with high Coulombic *** highest specific capacitance obtained was 325.20 F/g providing capacity retention of 94.79%after 10,000 cycles.A promising method of AC production for energy storage application has therefore been successfully demonstrated.

关键词： capacitance carbon starting

Evaluation of periglacial landforms and formation of soil properties on the Mount Honaz,SW Türkiye

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Journal of Mountain Science 2024年第9期21卷 3047-3067页

作者： SERİN Soner UNCU Levent dEdE Volkan TÜRKEŞmurat Institute of Social Sciences İstanbul Universityİstanbul 34119Türkiye department of Geography BilecikŞeyh Edebali UniversityBilecik 11234Türkiye department of Geography Ardahan UniversityArdahan 75002Türkiye Center for Climate Change and Policy Studies Boğaziçi Universityİstanbul 34342Türkiye

The main aim of this study is to explain periglacial processes on the summits of Mount Honaz(2571 m a.s.l.),define periglacial landforms,and determine the relationships between morphometric features and topographic *** circles,stony earth circles,non sorted steps,and non sorted stripes were identified on the summits of Mount ***'s correlation coefficient(r)and linear regression analyses were performed by taking metric measurements from 125 periglacial landforms to describe their morphometric features(length,width,height)of periglacial landforms and explain the relationships between them and topographic factors(elevation,slope).To explain the relationships between periglacial landforms and soil properties,soil samples from 11 periglacial landforms were taken and *** landforms,which continue to develop on the summits of Mount Honaz today,have been evaluated with present climate *** of soil samples indicates a notable impact of parent material on the genesis of periglacial *** high ratio of organic matter in mud circle and non sorted step landforms and the high lime ratio in stony earth circle landforms prove a strong relationship between the formation mechanisms of landforms and the soil ***,it is consistent with the findings obtained from the analysis that severe periglacial processes and washing and scavenging events are experienced more on the northern slopes.

关键词： Periglacial processes and geomorphology Soil analysis Morphometric analysis Mount Honaz Türkiye

Immunomodulatory activity of polycaprolactone nanoparticles with calcium phosphate salts against Leishmania infantum infection

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Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 359-368页

作者： Kübra Kelleci Adil Allahverdiyev Melahat Bağırova murat Ihlamur EmrahŞefik Abamor department of Bioengineering Yildiz Technical UniversityIstanbulTurkey V.Akhundov National Scientific Research Medical Prophylactic Institute BakuAzerbaijan department of Electronics and Automation Biruni UniversityIstanbulTurkey

Objective:To prepare and characterize polycaprolactone(PCL)nanoparticles loaded with sonicator fragmented(SLA)and freeze-thaw Leishmania antigens(FTLA)and to investigate the in vitro immunogenicity of antigen-encapsulated nanoparticles with calcium phosphate ***:The water/oil/water binary emulsion solvent evaporation method was used to synthesize antigen-loaded PCL *** were characterized by scanning electron microscopy and zeta potential *** cytotoxicity in J774 macrophages in vitro was determined by MTT *** addition,the amount of nitric oxide and the level of cytokines produced by macrophages were determined by Griess reaction and ELISA method,*** protective effect of the developed formulations was evaluated by determining the infection index percentage in macrophages infected with Leishmania ***:Compared to the control group,SLA PCL and FTLA PCL nanoparticles with calcium phosphate adjuvant induced a 6-and 7-fold increase in nitric oxide,***,the vaccine formulations promoted the production of IFN-γand *** PCL and FTLA PCL nanoparticles combined with calcium phosphate adjuvant caused an approximately 13-and 11-fold reduction in infection index,respectively,compared to the control ***:The encapsulation of antigens obtained by both sonication and freeze-thawing into PCL nanoparticles and the formulations with calcium phosphate adjuvant show strong in vitro immune stimulating ***,PCL-based antigen delivery systems and calcium phosphate adjuvant are recommended as a potential vaccine candidate against leishmaniasis.

关键词： Leishmaniasis Calcium phosphate Polycaprolactone Nanoparticle Antigen delivery system Adjuvant Vaccine design

Semiotics and political discourse in the post-truth era

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Language and Semiotic Studies 2024年第1期10卷 65-82页

作者： BetülÇanakpınar murat Kalelioğlu V.doğan Günay Istinye University IstanbulTürkiye School of Foreign Languages T C Mardin Artuklu UniversityMardinTürkiye Faculty of Literature Department of LinguisticsDokuz Eylül UniversityIzmirTürkiye

The concept of post-truth has been on the world’s agenda since *** this concept,which is frequently encountered in political life,provides the speaker with a freer speaking ***,instead of presenting the reality to their constituents as it is,want to reshape this reality according to their own ideology and present it to the *** have certain objectives in creating such a virtual *** aims can be listed as keeping the voters,increasing the voting potential,and attracting undecided voters to their *** common result of all these aims is to gain political power or to remain in the existing ***-truth reality is constructed relatively more easily in social media *** construction of reality can be through beliefs or *** such ways,the recipient is tried to be persuaded,and thus behavioral change is *** of the most necessary subjects for this artificial reality atmosphere is the *** idea that the anti-subject does not know the truth that we(you and I)know and believe and is trying to destroy it is the main theme of post-truth *** try to persuade the voters to believe in their own truth by expressing this idea to *** are many examples of this around the *** this study,firstly,the concept of post-truth is examined and its various definitions are *** distinctions between the concepts of real and truth are analyzed and then it is explained how and for what purposes the concept of post-truth is used in *** the comparison of post-truth and fake news,the concept is discussed within the framework of sender-receiver interaction in terms of *** concept is tried to be elucidated with the modalities such as/convincing/,/believing/,/being/,/appearing/.Besides,using the semiotic square,the study also tries to reveal the different purposes and forms of use of the concept of *** a result,it has been observed

关键词： semiotics discourse politics post-truth fake news

dynamic Pricing Strategies Using Artificial Intelligence Algorithm

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Open Journal of Applied Sciences 2024年第8期14卷 1963-1978页

作者： murat Basal Emel Saraç Kadir Özer Logistics Vocational School Istanbul Gelisim University Istanbul Turkey department of Business Administration Institute of Social Sciences Ostim Technical University Ostim Turkey department of Insurance Faculty of Financial Sciences Ankara Hac Bayram Veli University Ankara Turkey

Pricing strategies can have a huge impact on a company’s success. This paper focuses on the advantages and disadvantages of using artificial intelligence in dynamic pricing strategies. A good understanding of the possible benefits and challenges will help companies to understand the impact of their chosen pricing strategies. AI-driven dynamic pricing has great opportunities to increase a firm’s profits. Firms can benefit from personalized pricing based on personal behavior and characteristics, as well as cost reduction by increasing efficiency and reducing the need to use manual work and automation. However, AI-driven dynamic rewarding can have a negative impact on customers’ perception of trust, fairness and transparency. Since price discrimination is used, ethical issues such as privacy and equity may arise. Understanding the businesses and customers that determine pricing strategy is so important that one cannot exist without the other. It will provide a comprehensive overview of the main advantages and disadvantages of AI-assisted dynamic pricing strategy. The main objective of this research is to uncover the most notable advantages and disadvantages of implementing AI-enabled dynamic pricing strategies. Future research can extend the understanding of algorithmic pricing through case studies. In this way, new, practical implications can be developed in the future. It is important to investigate how issues related to customers’ trust and feelings of unfairness can be mitigated, for example by price framing.

关键词： Artificial Intelligence Algorithm dynamic Pricing Strategy