Synthesis, Spectral Analysis and Antimicrobial Activity of New Pd (Ⅱ) Complexes Involving 5,6-Dimethylbenzimidazole

作     者：Murat TÜRKYILMAZ Murat DÖNMEZ Özlen ALTUN Murat TÜRKYILMAZ;Murat DÖNMEZ;Özlen ALTUN

作者机构：Department of ChemistryTrakya University22030 EdirneTurkey 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：2023年第39卷第6期

页      面：968-975页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the Trakya University Research Fund(No.TUBAP-2014-106) 

主　　题：N-Heterocyclic carbene Palladium(Ⅱ)-NHC complex Structural analysis Antimicrobial activity 

摘      要：In this study,firstly,3-bromopropanenitrile(2a),ethyl bromoacetate(2b),and 2-bromoethan-1-amine(2c)were added to 5,6-dimethylbenzimidazole(1)and symmetrically-connected N-heterocyclic carbenes(NHC)[(3a-3c)]were ***,the NHC precursor compounds were reacted with PdCl2 and Pd(Ⅱ)-NHC complexes[(4a—4c)]were *** synthesized NHC precursors(3a-3c)and Pd(Ⅱ)-NHC complexes(4a—4c)were characterized by different spectroscopic *** antibacterial activities of these products were measured against bacteria and fungus with the disc diffusion ***(Ⅱ)-NHC complexes had higher antibacterial activity than the NHC *** synthesized compounds showed antimicrobial activity with different properties from each *** vitro biological activities of salts and metal complexes on selected bacteria were determined by the broth dilution method based on Clinical and Laboratory Standards Institute guidelines.1,3-Bis-(2-hydroxyethyl)imidazolinium bromide and 3-(2-ethoxy-2-oxoethyl)-1-(3-aminopropyl)-^(1)H-imidazole-3-ium bromide had activity against Escherichia coli.