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Size-fractionated carbonaceous particles and climate effects in the eastern region of Myanmar

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Particuology 2024年第7期90卷 31-40页

作者： Mai Kai Suan Tial Nwe Nwe Kyi muhammad Amin Mitsuhiko Hata Masami Furuuchi Rahmi Mulia Putri Phakphum Paluang Phuchiwan Suriyawong Worradorn Phairuang Department of Electrical Power Engineering Yangon Technological UniversityYangon11011Myanmar Faculty of Geosciences and Civil Engineering Institute of Science and EngineeringKanazawa UniversityKanazawaIshikawa920-1192Japan Faculty of Engineering Maritim University of Raja Ali HajiTanjung PinangKepulauan Riau 29115Indonesia Graduate School of Natural Science and Technology Kanazawa UniversityKanazawaIshikawa920-1192Japan Department of Geography Faculty of Social SciencesChiang Mai UniversityMuangChiang Mai50200Thailand Research Unit for Energy Economics and Ecological Management Multidisciplinary Research InstituteChiang Mai UniversityMuangChiang Mai50200Thailand

This study reports on an investigation of fine and coarse carbonaceous particulate matters(PM)in Tachileik,eastern Myanmar,during the dry and wet seasons of *** carbon compositions,including organic carbon(OC)and elemental carbon(EC),in each size(PM10-2.5,PM2.5-1.0,and PM1.0-0.5)were determined by a carbon *** average total mass concentration of the three fractions of particle samples during the dry season was higher(51.23±23.86μg/m3)than that of the wet season(14.00±5.26μg/m3).The results indicate that OC and EC levels were highest for PM1.0-0.5 during the dry season and the sizes were similar for both *** OC/EC ratios varied in different seasons,from 1.93 to 4.40 and 4.13 to 5.25 in the dry and wet seasons,*** was sub-divided into char-EC and soot-EC;the char-EC/soot-EC in the dry season was higher than in the wet season,signifying that biomass burning is the main particle source during the dry ***,vehicle emissions dominated during the wet *** effective carbon ratio(ECR)suggested that finer particles contributed more to global *** information is important in terms of air quality control and mitigation in Myanmar and elsewhere.

关键词： Air quality Biomass burning Carbon Coarse particles Fine particles Myanmar

Innovative COVID-19 Screening: RT-LAMP Assay for Spike and NSP1 Proteins

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Journal of Clinical and Nursing Research 2024年第6期8卷 256-265页

作者： muhammad Yousaf Amber Khan Department of Biosciences COMSATS University IslamabadPark RdIslamabad Capital Territory 45550Pakistan Department of Biosciences Shaheed Zulfikar Ali Bhutto Institute of Science and Technology(SZABIST)KarachiPakistan

Coronavirus disease(COVID-19)is a serious respiratory disease that spreads through the coronavirus *** soon became a pandemic after its appearance in 2019 and demanded new techniques for its identification and *** to this situation,RT-LAMP appears to be a novel method for the identification of COVID-19 because of its vast applications,including cost-effectiveness and *** research highlights the use of RT-LAMP,a more sensitive test than RT-PCR,for the assessment of SARS-CoV-2,the severe acute respiratory *** identify the spike(S)and NSP1 protein using RT-LAMP,170 total samples of coronavirus-suspected patients were served in this *** certifications and bioethical considerations were taken into *** the sample was extracted from the patient's swabs,RNA was isolated,extracted,and *** response was then run on the RT-LAMP at the ideal temperature,and the outcomes could be observed with the unaided eye as they changed from pink to *** is a simple method of determining if the test is positive or *** this purpose,both RT-LAMP and RT-PCR tests are used during these *** linked with COVID-19 testing including S,nspl,and ORF are suited to coronavirus testing;they have 100%specificity and low sensitivity,but S has more specificity and sensitivity than nspl and ORF,*** of the 95 positive samples,89(93.68%)samples yielded favorable outcomes utilizing RT-LAMP,while 55 negative samples yielded 100%positive *** present research demonstrates that RT-LAMP is less sensitive yet more selective for coronavirus detection.

关键词： COVID-19 NSP1 Spike RT-LAMP

p21活化激酶4致癌机制及与消化系统恶性肿瘤发生发展的关系

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山东医药 2024年第20期64卷 98-102页

作者： ali muhammad 胡继成周明艳祝哲潘宜鹏徐剑海南医科大学第二附属医院肝移植科海口570311 海南医科大学第二附属医院临床医学研究所

p21活化激酶4(PAK4)是一种丝氨酸/苏氨酸蛋白激酶,在多种消化系统肿瘤中过表达,是肿瘤细胞信号转导的关键因子之一。PAK4过表达与肿瘤细胞的增殖、迁移、侵袭、免疫逃逸及耐药性有关。在消化系统肿瘤中,PAK4可通过影响细胞周期、细胞凋... 详细信息

p21活化激酶4(PAK4)是一种丝氨酸/苏氨酸蛋白激酶,在多种消化系统肿瘤中过表达,是肿瘤细胞信号转导的关键因子之一。PAK4过表达与肿瘤细胞的增殖、迁移、侵袭、免疫逃逸及耐药性有关。在消化系统肿瘤中,PAK4可通过影响细胞周期、细胞凋亡及细胞骨架重塑等生物学过程,促进肿瘤的恶性行为。多项研究表明,PAK4抑制剂显示出抑制肿瘤增殖和转移的潜力,在联合化疗中具有较好的应用前景。

关键词： p21活化激酶4 PAK4抑制剂消化系统肿瘤

Anti-obesity effect and UHPLC-QTOF-MS/MS based metabolite profiling of Solanum nigrum leaf extract

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Asian Pacific Journal of Tropical Biomedicine 2022年第4期12卷 164-174页

作者： Zain Ul Aabideen muhammad Waseem mumtaz muhammad Tayyab Akhtar muhammad Asam Raza Hamid Mukhtar Ahmad Irfan Syed ali Raza muhammad Nadeem Yee Soon Ling Department of Chemistry University of GujratGujratPakistan Institute of Industrial Biotechnology GC University LahoreLahorePakistan Department of Chemistry College of ScienceKing Khalid UniversityP.O.Box 9004Abha 61413Saudi Arabia Research Center for Advanced Materials Science King Khalid UniversityP.O.Box 9004Abha 61413Saudi Arabia Department of Chemistry GC University LahoreLahorePakistan Sabah Occupational Safety Health and Environment AssociationLot331st FloorBlock EIramanis CenterJalanLinatas88450Kota KinabaluSabahMalaysia

Objective:To evaluate the antioxidant potential and pancreatic lipase inhibitory action of optimized hydroethanolic extracts of Solanum ***:Optimized extraction for maximum recovery of metabolites was performed using a combination of freeze-drying and ultrasonication followed by determination of antioxidant and antiobesity *** ultra-high performance liquid chromatography equipped with mass spectrometry was used to analyze metabolite profiling of Solanum *** studies were performed using molecular docking and electrostatic potential analysis for individual *** hypolipidemic potential of the most potent extract was assessed in the obese mice fed on fat rich ***:The 80%hydroethanolic extract exhibited the highest extract yield,total phenolic contents,total flavonoid contents along with the strongest 2,2-diphenyl-1-picrylhydrazyl scavenging activity,total antioxidant power,and pancreatic lipase inhibitory *** 80%hydroethanolic extract not only regulated the lipid profile of obese mice but also restricted the weight gain in the liver,kidney,and *** 80%hydroethanolic extract also reduced alanine transaminase and aspartate transaminase concentrations in *** effects of plant extract at 300 mg/kg body weight were quite comparable with the standard drug ***:Solanum nigrum is proved as an excellent and potent source of secondary metabolites that might be responsible for obesity mitigation.

关键词： Solanum nigrum Ultrasonication Metabolite profiling Total phenolic contents Total flavonoid content Antioxidant DPPH Total antioxidant power Pancreatic lipase UHPLC-QTOF-MS/MS Antiobesity Mice Hypolipidemic Molecular docking

A Robust Emergency Messages Routing Scheme for Urban VANETs

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Computers, Materials & Continua 2022年第8期72卷 2617-2632页

作者： mumtaz ali Shah Farrukh Zeeshan Khan Ghulam Abbas Department of Computer Science University of Engineering and TechnologyTaxilaPakistan Telecommunications and Networking Research Center GIK Institute of Engineering Sciences and TechnologyTopi23640Pakistan

Vehicular ad-hoc networks(VANETs)play an essential role in enhancing transport infrastructure by making vehicles intelligent and proficient in preventing traffic ***-based greedy protocols pick the next route vehicle for transmitting emergency messages(EMs)depending upon the present location of adjacent vehicles towards sink vehicles by using an optimal uni-directional road traffic ***,such protocols suffer performance degradation by ignoring the moving directions of vehicles in bi-directional road traffic where topological changes happen *** to the high number of vehicles,it is essential to broadcast EMs to all vehicles to prevent traffic delays and collisions.A cluster-based EM transmitting technique is proposed in this *** urban VANETs,this paper pioneers the clustering of bi-directional road traffic for robust and efficient routing of *** this regard,this paper introduces a routing protocol,namely,the bi-directional urban routing protocol(BURP).In addition to the paths and relative locations of vehicles,BURP takes account of the distance parameter by using the Hamming distance function to determine the direction ofmotion of vehicles and communicates EMs through the cluster head(CH).Amodified k-medoids algorithm is presented for the clustering of bi-directional road traffic.A median method is presented for selecting CH to ensure the longrunning of a *** results show that BURP provides enhanced throughput,a maximized packet delivery ratio,low energy consumption,and network delay relative to eminent routing protocols.

关键词： Vehicular ad hoc networks bi-directional road traffic routing protocol emergency message broadcasting direction-based greedy forwarding

Insecticidal Potential of α-Pinene and β-Caryophyllene against Myzus persicae and Their Impacts on Gene Expression

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Phyton-International Journal of Experimental Botany 2023年第7期92卷 1943-1954页

作者： Talha ali Chohan Tahir ali Chohan muhammad Zahid mumtaz muhammad Waqar Alam Salah ud Din Iqra Naseer Ayesha Riaz Tayyeba Naseem Areeba Iftikhar Dur ENajaf ali Mubashir Hassan Hayssam M.ali Institute of Molecular Biology and Biotechnology(IMBB) The University of LahoreLahore54000Pakistan Institute of Pharmaceutical Sciences University of Veterinary and Animal SciencesLahore54000Pakistan Deparment of Plant Pathology University of OkaraOkara56300Pakistan Deparment of Bioinformatics University of OkaraOkara56300Pakistan Department of Soil Science The Islamia University of BahawalpurBahawalpur63100Pakistan Department of Zoology The Islamia University of BahawalpurBahawalpur(Bahawalnagar Campus)63100Pakistan The Steve and Cindy Rasmussen Institute for Genomic Medicine Nationwide Children’s HospitalColumbusOhio43205USA Department of Botany and Microbiology College of ScienceKing Saud UniversityRiyadh11451Saudi Arabia

Myzus persicae(***)is now considered a threat to agricultural crops due to economic *** synthetic insecticides applied every year against ***,are reported to be unsafe for environment,humans,and beneficial ***,several species of Myzus have been found to develop resistance due to over application of these ***,it is required to find some novel insecticide that would be safe for the environment as well as for *** the current study,two major pure constituentsα-pinene andβ-caryophyllene were evaluated for their insecticidal potential against *** using a fumigant toxicity ***,impact ofα-pinene andβ-caryophyllene on expression of five different genes,e.g.,HSP 60,FPPS I,OSD,TOL and ANT responsible for reproduction,dispersion,and growth of *** has also been *** perform fumigant toxicity assay,five different concentrations(3.5,4,4.5,5 and 6μL L−1)ofα-pinene andβ-caryophyllene were *** concentration(LC)was calculated,and gene expression studies were executed through qRT PCR at LC30 ofα-pinene andβ-*** constituents demonstrated excellent fumigant toxicity effects against *** at all five ***,α-pinene shows significantly better results(98%)as compared toβ-caryophyllene(80%)after 72 h at 6μL L−1 of *** highest upregulation in expression was demonstrated at LC30 dose ofα-pinene in five in three out of five genes understudy(TOL,ANT,and FPPS I).Conversely,two genes HSP 60 and OSD demonstrated downregulation at LC30 dose ofβ-***,our results highlighted the promising insecticidal potential of both compoundsα-pinene andβ-caryophylleneby interfering with the reproduction and development related processes in ***,allowing us to recommend the phytoconstituents under investigation as an ecofriendly alternative to synthetic insecticides.

关键词： Fumigation M.persicae gene expression real time PCR α-pinene β-caryophyllene

Leveraging the Role of Dynamic Reconfigurable Antennas in Viewpoint of Industry 4.0 and Beyond

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Research 2023年第3期6卷 35-56页

作者： Abdul Jabbar muhammad ali Jamshed Qammer Abbasi muhammad ali Imran Masood Ur-Rehman James Watt School of Engineering University of GlasgowGlasgowUK

Industry 4.0 is a digital paradigm that refers to the integration of cutting-edge computing and digital technologies into global industries because of which the state of manufacturing,communication,and control of smart industries has changed *** 4.0 has been profoundly influenced by some major disruptive technologies such as the Internet of Things(IoT),smart sensors,machine learning and artificial intelligence,cloud computing,big data analytics,advanced robotics,augmented reality,3D printing,and smart adaptive *** this review paper,we discuss physical layer-based solutions with a focus on high reliability and seamless connectivity for Industry 4.0 and beyond ***,we present a harmonized review of the industrial revolution journey,industrial communication infrastructure,key performance requirements,and potential sub-6-GHz frequency ***,based on that,we present a comprehensive review of intelligent tunable dynamic antenna systems at sub-6 GHz as key enablers for next-generation smart industrial ***-of-the-art smart antenna techniques such as agile pattern reconfigurability using electrical components,machine learning-and artificial intelligence-based agile beam-scanning antennas,and beam-steerable dynamic metasurface antennas are thoroughly reviewed and *** unfolded the exciting prospects of reconfigurable dynamic antennas for intelligent and reliable connectivity in application scenarios of Industry 4.0 and beyond such as Industrial IoT and smart manufacturing.

关键词： antenna IoT smart

Antibody Pattern: Correlation of Age and Gender in ANA and Anti-ds-DNA Prevalence

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Journal of Clinical and Nursing Research 2024年第6期8卷 373-381页

作者： Usama Ahmed Hijazi Mallick Amber Khan muhammad Zubair Department of Medicine School of Biomedical EngineeringShenzhen University Medical SchoolShenzhen 518060China Dow International Medical College Karachi Pakistan Department of Biosciences Shaheed Zulfikar Ali Bhutto Institute of Science and Technology(SZABIST)KarachiPakistan Institute of Biological Sciences Khwaja Fareed University of Engineering and Information TechnologyRahim Yar KhanPakistan

The study was designed to find the prevalence of ANA antibodies and anti-dsDNA antibodies in samples tested at AFIP Rawalpindi and their correlation with age and gender and to find positive and negative predictive values of ANA *** this purpose,twelve thousand nine hundred sixty-seven(12,967)patients were analyzed for ANA with four hundred sixty-eight(468)healthy samples tested as control and four thousand seven hundred three(4,703)patients tested for ds-DNA *** data of all samples tested by indirect immunofluorescence(IF)for ANA antibodies and dsDNA antibodies was *** address positive and negative predictive values another control group(autoimmunity not suspected)of serum samples was taken from the healthy *** the first group,age,gender,ANA antibodies and ds-DNA antibodies results(both tests performed by IIF)data was collected from a computer record cell;for the second control group,ANA antibodies were performed by IIF.12,967 and 4,703 samples(Group 1)were tested for ANA antibodies and dsDNA antibodies,respectively,during this period.1,119(9%)and 99(2%)were found positive for ANA antibodies and ds DNA *** these positive samples,850(76%)and 73(74%)were females *** predisposition towards autoimmunity(ANA)was found significant with a P value of(P=0.001).Relation of age was also found significant with anti-ANA antibodies with a P value of(P=0.001).This study shows a negative correlation between age(P=0.025)and gender(P=0.001)with anti-dsDNA which is also *** prevalence was found below the mean age of 38 years(SD±16.635)for ANA antibodies and the mean age of 35 years(SD±15.066)for ds-DNA *** age of ANA antibodies and dsDNA antibodies positive patients ranged from 1 year old to 98 years old and 2 years old to 95 years old *** the second(autoimmunity-free)control group,a total of 468 samples were tested for ANA antibodies and 9(2%)were found ***

关键词： ANA Anti ds-DNA Autoimmunity SLE Immune fluorescence

Hybrid DFT study of structural,electronic,magnetic and elastic properties of laves phase binary intermetallics RFe_(2)(R=La,Ce,Pr and Nd)

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稀土学报:英文版 2023年第9期41卷 1367-1375,I0004页

作者： Murad Murad Zahid ali muhammad Idrees Centre for Computational Materials Science Department of PhysicsUniversity of MalakandChakdaraDir(Lower)18800KPPakistan

Hybrid density functional theory was used to investigate the structural,electronic,magnetic and elastic properties of the Laves phase binary intermetallics RFe_(2)(R=La,Ce,Pr and Nd) in C_(15) crystal *** calculated lattice constants of these materials are found in good agreement with the *** band structures and density of states distribution confirm the metallic nature of all these *** optimized energies in different magnetic phases and magnetic susceptibilities by postDFT treatments confirm that all the understudy compounds are ferromagnetic in *** parameters were calculated from the cubic elastic coefficients C_(11),C_(12) and C_(44).The elastic properties reveal that these intermetallics are incompressible,ductile,elastically anisotropic and mechanically *** on the metallic nature and ferromagnetic properties,it is expected that these intermetallics are suitable materials for spintronic technology.

关键词： Intermetallics Laves phase Density functional theory Electronic band structures Magnetic properties Elastic properties