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Prevalence of post-traumatic stress disorder and depressive symptoms among civilians residing in armed conflict-affected regions:a systematic review and meta-analysis

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General Psychiatry 2024年第3期37卷 324-334页

作者： Syed Hassan Ahmed Aabia Zakai Maha Zahi muhammad youshay jawad Rui Fu Michael Chaiton Dow University of Health Sciences KarachiPakistan Department of Psychiatry and Behavioral Health Penn State College of MedicineHersheyPennsylvaniaUSA Dalla Lana School of Public Health University of TorontoTorontoOntarioCanada institute of Mental Health Policy Research The Center of Addiction and Mental HealthTorontoOntarioCanada

Background Globally,populations afflicted by armed conflict are known to have high rates of mental health *** This meta-analysis aims to estimate the prevalence of post-traumatic stress disorder(PTSD)and depressive symptoms among civilians residing in armed conflictaffected *** This meta-analysis was conducted in accordance with the Preferred Reporting Items forSystematic Reviews and Meta-Analyses.A literature search employing MEDLINE(R),Embase Classic+Embase,APA PsyclNFO,Ovid Healthstar,Journal@Ovid Full Text,Cochrane,PTSDpubs and CINAHL was conducted from inception until 19 March 2024 to identify relevant *** assessment was performed using the Joanna Briggs Institute Critical Appraisal Checklist for Prevalence Studies,and a Comprehensive Meta-Analysiswas usedto conduct the statistical *** The search yielded 38595 articles,of which 57 were considered eligible for *** included studies comprised data from 64596 *** estimated a prevalence of 23.70%(95%CI 19.50%to28.40%)forPTSD symptomsand 25.60%(95%Cl 20.70%to 31.10%)for depressive features among war-afflicted *** subgroup analysis based on time since the war and the country's economic status revealed the highest prevalence for both PTSD and depressive symptoms was present during the years of war and in low/*** The results of this study provide conclusive evidence of the detrimental impacts of armed conflict on mental health ***,it is crucial to emphasise the significance of both physical and mental health in the aftermath of war and take appropriate humanistic measures to overcome challenges in the management of psychiatric illnesses.

关键词： analysis stress armed

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Evaluation of microstructure and mechanical properties of squeeze overcast Al7075-Cu composite joints

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China Foundry 2023年第1期20卷 29-39页

作者： muhammad Waqas Hanif Ahmad Wasim muhammad Sajid Salman Hussain muhammad jawad Mirza Jahanzaib Department of Industrial Engineering University of Engineering and Technology TaxilaPunjabPakistan

Al7075-Cu composite joints were prepared by the squeeze overcast *** effects of melt temperature,die temperature,and squeeze pressure on hardness and ultimate tensile strength(UTS)of squeeze overcast Al7075-Cu composite joints were *** experimental results depict that squeeze pressure is the most significant process parameter affecting the hardness and *** optimal values of UTS(48 MPa)and hardness(76 HRB)are achieved at a melt temperature of 800℃,a die temperature of 250℃,and a squeeze pressure of 90 *** electron microscopy(SEM)shows that fractured surfaces show flatfaced morphology at the optimal experimental ***-dispersive spectroscopy(EDS)analysis depicts that the atomic weight percentage of Zn decreases with an increase in melt temperature and squeeze *** optimal mechanical properties of the Al7075-Cu overcast joint were achieved at the Al2Cu eutectic phase due to the large number of copper atoms that dispersed into the aluminum melt during the solidification process and the formation of strong intermetallic *** relational analysis integrated with the Taguchi method was used to develop an optimal set of control variables for multi-response parametric *** tests were performed to validate the effectiveness of the employed *** manufacturing of squeeze overcast Al7075-Cu composite joints at optimal process parameters delivers a great indication to acknowledge a new method for foundry practitioners to manufacture materials with superior mechanical properties.

关键词： squeeze overcast joints Al7075-Cu composite joints mechanical properties gray relational analysis Taguchi method

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RUSAS: Roman Urdu Sentiment Analysis System

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Computers, Materials & Continua 2024年第4期79卷 1463-1480页

作者： Kazim jawad muhammad Ahmad Majdah Alvi muhammad Bux Alvi Faculty of Computer Science and Engineering Frankfurt University of Applied SciencesFrankfurt am Main60318Germany Technical Writer and Researcher Proteus Technologies LLCIslamabad04405Pakistan Faculty of Engineering The Islamia University of BahawalpurBahawalpur63100Pakistan

Sentiment analysis, the meta field of Natural Language Processing (NLP), attempts to analyze and identify thesentiments in the opinionated text data. People share their judgments, reactions, and feedback on the internetusing various languages. Urdu is one of them, and it is frequently used worldwide. Urdu-speaking people prefer tocommunicate on social media in Roman Urdu (RU), an English scripting style with the Urdu language *** have developed versatile lexical resources for features-rich comprehensive languages, but limitedlinguistic resources are available to facilitate the sentiment classification of Roman Urdu. This effort encompassesextracting subjective expressions in Roman Urdu and determining the implied opinionated text polarity. Theprimary sources of the dataset are Daraz (an e-commerce platform), Google Maps, and the manual effort. Thecontributions of this study include a Bilingual Roman Urdu Language Detector (BRULD) and a Roman UrduSpelling Checker (RUSC). These integrated modules accept the user input, detect the text language, correct thespellings, categorize the sentiments, and return the input sentence’s orientation with a sentiment intensity *** developed system gains strength with each input experience gradually. The results show that the languagedetector gives an accuracy of 97.1% on a close domain dataset, with an overall sentiment classification accuracy of94.3%.

关键词： Roman Urdu sentiment analysis Roman Urdu language detector Roman Urdu spelling checker flask

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Neural stem cell-based in vitro bioassay for the assessment of neurotoxic potential of water samples

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Journal of Environmental Sciences 2021年第3期33卷 72-86页

作者： muhammad Irfan Masood Natalie Tamara Hauke muhammad jawad Nasim muhammad Sarfraz Mahrukh Naseem Karl Herbert Schäfer Division of Bioorganic Chemistry School of PharmacySaarland UniversityD-66123 SaarbrückenGermany Applied Life Sciences University of Applied Sciences Kaiserslautern66482 ZweibrückenGermany ENS Group University of Applied Sciences Kaiserslautern66482 ZweibrückenGermany Abwasserverband Bergstrasse Altau 1069469 WeinheimGermany Institute of Pharmaceutical Sciences University of Veterinary and Animal Sciences54000 LahorePakistan Department of Zoology University of BalochistanQuetta 87550Pakistan

Intensive agriculture activities,industrialization and growing numbers of wastewater treatment plants along river banks collectively contribute to the elevated levels of neurotoxic pollutants in natural water reservoirs across *** established an in vitro bioassay based upon neural stem cells isolated from the subventricular zone of the postnatal mouse to evaluate the neurotoxic potential of raw wastewater,treated sewage effluent,groundwater and drinking *** toxic potential of water samples was evaluated employing viability,proliferation,differentiation and migration *** found that raw wastewater could reduce the viability and proliferation of neural stem cells,and decreased the neuronal and astrocyte differentiation,neuronal neurite growth,astrocyte growth and cell *** sewage water also showed inhibitory effects on cell proliferation and *** results indicated that relatively high concentrations of nitrogenous substances,pesticides,mercuric compounds,bisphenol-A,and phthalates,along with some other pollutants in raw wastewater and treated sewage water,might be the reason for the neuroinhibitory effects of these water *** model successfully predicted the neurotoxicity of water samples collected from different sources and also revealed that the incomplete removal of contaminants from wastewater can be problematic for the developing nervous *** presented data also provides strong evidence that more effective treatments should be used to minimize the contamination of water before release into major water bodies which may be considered as water reservoirs for human usage in the future.

关键词： Neural stem cells Subventricular zone Neurotoxicity Bioassay Treated sewage effluents Pesticides

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Clinical relevance of circulating non-coding RNAs in metabolic diseases:Emphasis on obesity,diabetes,cardiovascular diseases and metabolic syndrome

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Genes & Diseases 2023年第6期10卷 2393-2413页

作者： Abdullahi Dandare muhammad jawad Khan Aisha Naeem Afrose Liaquat Department of Biosciences COMSATS University IslamabadIslamabad 45550Pakistan Department of Biochemistry Usmanu Danfodiyo UniversitySokoto 840104Nigeria Ministry of Public Health POB42DohaQatar Department of Oncology Lombardi Comprehensive Cancer CenterGeorgetown University Medical CenterWashingtonDC 20057USA Shifa College of Medicine Shifa Tameer-E-Millat UniversityIslamabad 45550Pakistan

Non-coding RNAs(ncRNAs)participate in the regulation of several cellular processes including transcription,RNA processing and genome *** aberrant expression of ncRNAs is associated with several pathological *** this review,we focused on recent information to elucidate the role of various regulatory ncRNAs i.e.,micro RNAs(miRNAs),circular RNAs(circRNAs)and long-chain non-coding RNAs(lncRNAs),in metabolic diseases,e.g.,obesity,diabetes mellitus(DM),cardiovascular diseases(CVD)and metabolic syndrome(MetS).The mechanisms by which ncRNAs participated in disease pathophysiology were also *** regulate the expression of genes at transcriptional and translational *** modulate the regulation of gene expression via miRNA sponging activity,interacting with RNA binding protein and polymerase II transcription *** regulate the expression of genes by acting as a protein decoy,miRNA sponging,miRNA host gene,binding to miRNA response elements(MRE)and the recruitment of transcriptional element or chromatin *** examined the role of ncRNAs in the disease pathogenesis and their potential role as molecular markers for diagnosis,prognosis and therapeutic *** showed the involvement of ncRNAs in the onset of obesity and its progression to MetS and ***-192,miRNA-122,and miRNA-221 were dysregulated in all these metabolic *** ncRNAs,implicated in at least three diseases include miRNA-15a,miRNA-26,miRNA-27a,miRNA-320,and *** of ncRNAs increased the risk of development of DM and MetS and its progression to CVD in obese ***,these molecules are potential targets to arrest or delay the progression of metabolic diseases.

关键词： Biomarkers CircRNAs LncRNAs Metabolic diseases miRNAs Non-coding RNAs Therapeutic targets

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Identification of hsa_circ_0092576 regulatory network in the pathogenesis of coronary heart disease

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Genes & Diseases 2023年第1期10卷 26-28页

作者： Abdullahi Dandare muhammad Rafiq Afrose Liaquat Afraz Ahmad Raj muhammad jawad Khan Department of Biosciences COMSATS University IslamabadIslamabad 45550Pakistan Department of Biochemistry Usmanu Danfodiyo University SokotoSokoto P.M.B.2346Nigeria Department of Biochemistry Shifa College of MedicineShifa Tameer-E-Millat UniversityIslamabad 45550Pakistan Department of Psychosomatic Medicine and Psychotherapy University Medical CenterGottingen 37075Germany

Cardiovascular diseases(CVDs)are responsible for 30%of all deaths *** heart disease(CHD),is the most common form of CVD,accounting for 46%of male and 38%female cardiovascular deaths.1 CHD is characterized by chronic inflammation and endothelial injuries in coronary arteries,and subsequent development of atherosclerotic plaques which eventually leads to myocardial ischemia.

关键词： coronary injuries inflammation

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Provision of primary care by specialist physicians:a systematic review

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Family Medicine and Community Health 2020年第1期8卷 20-23页

作者： muhammad jawad Hashim Department of Family Medicine United Arab Emirates UniversityAl AinUnited Arab Emirates

Patients with stable chronic diseases such as diabetes and hypertension can be safely managed at the primary care *** many such patients continue to follow-up with specialists at a higher expense with no added *** introduce a new term to describe this phenomenon:scope inversion,defined as the provision of primary care by specialist *** aimed to quantify the extent of scope inversion by conducting a systematic *** and five other databases were searched using the keywords‘specialist AND(routine OR primary)AND provi*’as well as other *** search was limited to human research without restrictions on language or date of *** inclusion criterion was studies on rates of the provision of routine primary care by specialist *** observational studies met the inclusion criteria.A wide range of primary care involvement was observed among specialists,from 2.6%to 65%of clinic *** children,41.3%of visits with specialists were routine follow-ups for conditions such as allergic rhinitis and seborrhoeic dermatitis which could be managed in primary *** quality was moderate to low across the studies due to limitations of source data and varying definitions of primary *** physicians provide primary care to patients in a substantial proportion of clinic *** inversion is wasteful as it diverts patients to more expensive care without improving outcomes.A systems approach is needed to mitigate scope inversion and its harmful effects on healthcare service delivery.

关键词： routine physician involvement

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CASIA-Iris-Africa:A Large-scale African Iris Image Database

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Machine Intelligence Research 2024年第2期21卷 383-399页

作者： jawad muhammad Yunlong Wang Junxing Hu Kunbo Zhang Zhenan Sun School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China Center for Research on Intelligent Perception and Computing National Laboratory of Pattern RecognitionInstitute of AutomationChinese Academy of SciencesBeijing 100190China

Iris biometrics is a phenotypic biometric trait that has proven to be agnostic to human natural physiological *** on iris biometrics has progressed tremendously,partly due to publicly available iris *** databases have been available to researchers that address pressing iris biometric challenges such as constraint,mobile,multispectral,synthetics,long-distance,contact lenses,liveness detection,***,these databases mostly contain subjects of Caucasian and Asian docents with very few *** many investigative studies on racial bias in face biometrics,very few studies on iris biometrics have been published,mainly due to the lack of racially diverse large-scale databases containing sufficient iris samples of Africans in the public ***,most of these databases contain a relatively small number of subjects and labelled *** paper proposes a large-scale African database named Chinese Academy of Sciences Institute of Automation(CASIA)-Iris-Africa that can be used as a complementary database for the iris recognition community to mediate the effect of racial biases on *** database contains 28717 images of 1023 African subjects(2046 iris classes)with age,gender,and ethnicity attributes that can be useful in demographically sensitive studies of *** of specific application protocols are incorporated with the database to ensure the database’s variability and *** results of some open-source state-of-the-art(SOTA)algorithms on the database are presented,which will serve as baseline *** relatively poor performances of the baseline algorithms on the proposed database despite better performance on other databases prove that racial biases exist in these iris recognition algorithms.

关键词： African iris recognition racial bias iris image database biometrics iris recognition

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Transmission dynamics of Hand-Foot-Mouth Disease with partial immunity through non-integer derivative

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International Journal of Biomathematics 2023年第6期16卷 149-173页

作者： Rashid Jan Salah Boulaaras Sultan Alyobit muhammad jawad Department of Mathematics University of Swabi Swabi 23561Khyber PakhtunkhwaPakistan Department of Mathematics College of Sciences and Arts Qassim UniversityAr RassSaudi Arabia Department of Mathematics College of Science 8 Arts King Abdulaziz UniversityRabighSaudi Arabia

In this paper,we formulate the transmission phenomena of Hand-Foot-Mouth Disease(HFMD)through non-integer *** interrogate the biological meaningful results of the recommended system of *** basic reproduction number is determined through next generation method and the impact of different parameters on the reproduction number is examined with the help of partial rank correlation coeficient(PRCC)*** addition,we concentrated on qualitative analysis and dynamical behavior of HFMD ***'s and Schaefer's fixed-point theorems are used to analyze the uniqueness and existence of the solution of the proposed HFMD *** HFMD system's Ulam-Hyers stability has been confirmed to be *** highlight the impact of the parameters on the dynamics of HFMD,we performed several simulations through numerical scheme to conceptualize the transmission route of the *** be more specific,numerical simulations are used to visualize the effect of input parameters on the systems *** have shown the key input parameters of the system for the control of infection in the society.

关键词： Hand-Foot-Mouth Disease fractional derivatives mathematical model threshold parameter numerical scheme dynamical behavior

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Evaluating therapeutic potential of coriander seeds and leaves(Coriandrum sativum L.) to mitigate carbon tetrachloride-induced hepatotoxicity in rabbits

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Asian Pacific Journal of Tropical Medicine 2018年第3期11卷 209-213页

作者： muhammad jawad Iqbal Masood Sadiq Butt Aamir Shehzad muhammad Asghar National Institute of Food Science & TechnologyFaculty of FoodNutrition and Home SciencesUniversity of AgricultureFaisalabadPakistan Department of Biochemistry Unirersity of AgricultureFaisalabadPakistan

Objective: To evaluate the hepatic and renal protective potential of coriander seeds and leaves using animal feed model. Methods: Coriander seeds-and leaves-based sauces were administrated to normal(Study Ⅰ) and carbon tetrachloride(2 mL/kg B.W.)-induced hepatotoxic rabbits(Study Ⅱ). Hepatic and renal biomarkers like aspartate aminotransferase,alanine aminotransferase. alkaline phosphatase, superoxide dismutase and catalase were measured. Results: Coriander leaves-based sauce exerted more decline(P<0.05) in serum aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase levels in the study Ⅱ as 18.32%. 19.91% and 21.24%, respectively. While, hepatic superoxide dismutase and catalase levels were raised significantly(P<0.05) in both studies. Renal parameters also depicted positive impact by the provision of developed sauces. Conclusions: Coriander seeds and leaves based sauces are effective in alleviating the hepato/renal toxicity. The hepatoprotective effect of coriander leaves is more pronounced as compared to coriander seeds.

关键词： Coriander seeds Coriander leaves Hepatoprotective potential Hepatotoxicity Rabbits

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