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Rice science 2024年第2期31卷 129-133,I0001-I0016页

作者： ZHANG Huali CHEN Junyu LI Ruiqing WANG Huimei DAI Dongqing LIANG Minmin WU Mingyue ma Liangyong State Key Laboratory of Rice Biology and Breeding/Chinese National Center for Rice Improvement China National Rice Research InstituteHangzhou 310006China

Two-line hybrid rice with excellent quality is preferred in the Chinese ***,there is a trade-off between reducing costs for hybrid seed production and lowering the outcrossing rate of the sterile line,which is largely determined by the stigma exsertion rate(SER).In this study,we constructed mutants of male sterility lines with improved grain length(GL)and SER in three elite early-season indica rice varieties through targeted manipulation of the TMS5 and GS3 genes using CRISPR/Cas9-mediated multiplex *** obtained a series of marker-free gs3 single mutants and gs3tms5 double mutants with significantly higher SER,longer grains,and increased 1000-grain weight compared with the wild type(WT).Importantly,the typically thermo-sensitive genic male sterile(TGMS)trait with a higher SER was observed in gs3tms5 mutants,and their f1 hybrids exhibited remarkable improvements in grain shape and yield-related *** findings provided an efficient method to generate new valuable TGMS germplasm with improved SER through the mutagenesis of GS3 and TMS5 synergistically,and demonstrated that GS3 had pleiotropic effects on grain size,SER,and grain quality in early-season indica rice.

关键词： sterile elite season

Identification of 3-ketocapnine reductase activity within the human microbiota

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mLife 2024年第2期3卷 307-316页

作者： Xiaotong Wu Lukuan Hou Haili Zhang Yi ma Jufang Wang Mingwei Cai Xiaoyu Tang School of Biology and Biological Engineering South China University of TechnologyGuangzhouChina Institute of Chemical Biology Shenzhen Bay LaboratoryShenzhenChina College of Chemistry and Pharmacy Northwest A&F UniversityYanglingChina

The microbial synthesis of sulfonolipids within the human body is likely involved in maintaining human health or causing ***,the enzymes responsible for their biosynthesis remain largely *** this study,we identified and verified the role of 3-ketocapnine reductase,the third-step enzyme,in the four-step conversion of L-phosphoserine into sulfobacin B both in vivo and in *** finding builds upon our previous research into sulfonolipid biosynthesis,which focused on the vaginal bacterium Chryseobacterium gleum DSM 16776 and the gut bacterium Alistipes finegoldii DSM *** comprehensive gene mapping,we demonstrate the widespread presence of potential sulfonolipid biosynthetic genes across diverse bacterial species inhabiting various regions of the human *** findings shed light on the prevalence of sulfonolipid-like metabolites within the human microbiota,suggesting a potential role for these lipid molecules in influencing the intricate biointeractions within the complex microbial ecosystem of the human body.

关键词： 3-ketocapnine reductase capnines human microbiota sulfonolipids

Enhanced cyclic stability of partially disordered spinel cathodes through direct fluorination with gaseous fluorine

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Rare Metals 2024年第4期43卷 1635-1646页

作者： Yong-Nian ma Ling-Chen Kong Shao-Shan Chen Yong Wang Li-Dong Sun Cong Peng Meng-Meng Qin Yu Li Wei feng Tianjin Key Laboratory of Composite and functional materials School of Materials Science and EngineeringTianjin UniversityTianjin300072China Institute of Advanced Technology and Equipment Beijing University of Chemical TechnologyBeijing100029China

Spinel-type cathodes are considered an optimal substitute for conventional layered oxide cathodes owing to their use of inexpensive and earth-abundant manganese as the redox-active ***,the introduction of cation disorder can effectively suppress the detrimental two-phase reaction to realize high capacities in a wide voltage ***,the continuous capacity decay during cycles has hindered the widespread application of these cathode *** fluorides exhibit excellent electrochemical stability at high voltage;therefore,in this study,the direct f2 gas reaction with a partially disordered spinel cathode(Li_(1.6)Mn_(1.6)O_(3.7)f_(0.3,)LMOf1.6)was initially applied to investigate the impacts of fluorination on the surface structure and electrochemical *** inorganic fluorinated layer,mainly containing Lif,was distributed uniformly on the surface of LMOf1.6nanoparticles after fluorination for an appropriate time without the turbulence caused by the valency of manganese cation,which improved the capacity retention and rate capability by the suppression of structural damage,parasitic reaction,and cation *** LMOf1.6cathode fluorinated for 0.5 h exhibited a capacity of283.6 mah·g^(-1)at 50 ma·g^(-1)and an enhanced capacity retention of 29.6%after 50 cycles in the voltage range of1.5-4.8 V,as compared to the pristine LMOf1.6 with only27.9%capacity retention.

关键词： Spinel-type cathodes Direct fluorination Capacity retention ability High rate capability

Identification of porcine fast/slow myogenic exosomes and their regulatory effects on lipid accumulation in intramuscular adipocytes

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1512-1527页

作者： Tiantian Zhao Tingting Tian He Yu Chaoyue Cao Ziyi Zhang Zhaozhao He Zeqiang ma Rui Cai fengna Li Weijun Pang Laboratory of Animal fat Deposition&Muscle Development College of Animal Science and TechnologyNorthwest A&F UniversityYangling 712100ShaanxiChina Laboratory of Animal Nutritional Physiology and Metabolic Process Key Laboratory of Agro‑ecological Processes in Subtropical RegionInstitute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125HunanChina

Background Pork quality is affected by the type of muscle fibers, which is closely related to meat color, tenderness and juiciness. Exosomes are tiny vesicles with a diameter of approximately 30–150 nm that are secreted by cells and taken up by recipient cells to mediate communication. Exosome-mediated muscle-fat tissue crosstalk is a newly discovered mechanism that may have an important effect on intramuscular fat deposition and with that on meat quality. Various of adipose tissue-derived exosomes have been discovered and identified, but the identification and function of muscle exosomes, especially porcine fast/slow myotube exosomes, remain unclear. Here, we first isolated and identified exosomes secreted from porcine extensor digitorum longus(EDL) and soleus(SOL), which represent fast and slow muscle, respectively, and further explored their effects on lipid accumulation in longissimus dorsi *** Porcine SOL-derived exosomes(SOL-EXO) and EDL-derived exosomes(EDL-EXO) were first identified and their average particle sizes were approximately 84 nm with double-membrane disc-shapes as observed via transmission electron microscopy and scanning electron microscopy. Moreover, the intramuscular fat content of the SOL was greater than that of the EDL at 180 days of age, because SOL intramuscular adipocytes had a stronger lipid-accumulating capacity than those of the EDL. Raman spectral analysis revealed that SOL-EXO protein content was much greater than that of EDL-EXO. Proteomic sequencing identified 72 proteins that were significantly differentially expressed between SOL-EXO and EDL-EXO, 31 of which were downregulated and 41 of which were upregulated in *** Our findings suggest that muscle-fat tissue interactions occur partly via SOL-EXO promoting adipogenic activity of intramuscular adipocytes.

关键词： Adipogenesis Exosome Extensor digitorum longus Intramuscular adipocyte Muscle-fat tissue interaction Pig Soleus

Regulation effects of water and nitrogen on yield,water,and nitrogen use efficiency of wolfberry

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Journal of Arid Land 2024年第1期16卷 29-45页

作者： GAO Yalin QI Guangping ma Yanlin YIN Minhua WANG Jinghai WANG Chen TIAN Rongrong XIAO feng LU Qiang WANG Jianjun College of Water Conservancy and Hydropower Engineering Gansu Agricultural UniversityLanzhou 730070China Jingtaichuan Electric Power Irrigation Water Resource Utilization Center in Gansu Province Baiyin 730900China

Wolfberry(Lycium barbarum L.)is important for health care and ecological ***,it faces problems of low productivity and resource utilization during *** reasonable models for water and nitrogen management is important for solving these *** on field trials in 2021 and 2022,this study analyzed the effects of controlling soil water and nitrogen application levels on wolfberry height,stem diameter,crown width,yield,and water(WUE)and nitrogen use efficiency(NUE).The upper and lower limits of soil water were controlled by the percentage of soil water content to field water capacity(θ_(f)),and four water levels,i.e.,adequate irrigation(W0,75%-85%θ_(f)),mild water deficit(W1,65%-75%θ_(f)),moderate water deficit(W2,55%-65%θ_(f)),and severe water deficit(W3,45%-55%θ_(f))were used,and three nitrogen application levels,i.e.,no nitrogen(N0,0 kg/hm^(2)),low nitrogen(N1,150 kg/hm^(2)),medium nitrogen(N2,300 kg/hm^(2)),and high nitrogen(N3,450 kg/hm^(2))were *** results showed that irrigation and nitrogen application significantly affected plant height,stem diameter,and crown width of wolfberry at different growth stages(Pmaximum values were observed in W1N2,W0N2,and W1N3 *** weight per plant and yield of wolfberry first increased and then decreased with increasing nitrogen application under the same water *** weight per hundred grains and dry weight percentage increased with increasing nitrogen application under W0 ***,under other water treatments,the values first increased and then decreased with increasing nitrogen *** and its component of wolfberry first increased and then decreased as water deficit increased under the same nitrogen *** water use efficiency(IWUE,8.46 kg/(hm^(2)·mm)),WUE(6.83 kg/(hm^(2)·mm)),partial factor productivity of nitrogen(PfPN,2.56 kg/kg),and NUE(14.29 kg/kg)reached their highest values in W2N2,W1N2,W1N2,and W1N1 treatments.R

关键词： water deficit growth characteristics yield water and nitrogen use efficiency principal component analysis

Effect of Guanxin Danshen Dripping Pills on Coronary Heart Disease Comorbid with Depression or Anxiety: The ADECODE-Real World Study

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Chinese Journal of Integrative Medicine 2024年第5期30卷 443-448页

作者： WU Shi-hao SHI Wei-qi LI Yu-hang LIU Ru-hui HU Da-yi ZHENG Li-qiang ma Wen-lin Department of Geriatric Medicine Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Cardiology Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Cardiology Peking University People's HospitalBeijing 100044China School of Public Health Shanghai Jiao Tong UniversityShanghai 200030China

Objective: To evaluate the efficacy of Guanxin Danshen Dripping Pill(GXDSDP) in treating anxiety and depression in patients with coronary heart disease(CHD). Methods: A total of 1,428 patients diagnosed with CHD screened for anxiety, depression, and quality of life(QOL) at baseline received 0.4 g of GXDSDP treatment 3 times per day and returned for monthly reassessment. Patients were recruited after stable treatment for CHD and received assessment of General Anxiety Disorder-7(GAD-7), Patient Health Questionnaire-9(PHQ-9), and Seattle Angina Questionnaire(SAQ) for evaluating anxiety, depression, and *** were followed up 3 times, once every 4 weeks, during outpatient visits for 12 weeks. Results: At the third follow-up(f3), the anxiety symptom of 63.79%(673/1,055) of the patients improved to sub-clinical level, and the GAD-7 score improved significantly(8.11 vs. 3.87, Pficant improvement in PHQ-9 score(8.69 vs. 4.41, Pf3. All aspects of QOL significantly improved at the end of treatment compared to those at baseline(all Pfrequency(8.16vs. 9.10), treatment satisfaction(13.43 vs. 16.29), and disease perception(8.69 vs. 11.02). Conclusions: A fixed dosage of GXDSDP may be a potential treatment option for CHD patients comorbid with anxiety or depression.(Registration No. ChiCTR2100051523)

关键词： Guanxin Danshen Dripping Pill coronary heart disease depression anxiety quality of life Chinese medicine

Phosphate-Bismuthate Glass and fiber with Heavy Doping of Silver Nanoparticles(Invited)

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激光与光电子学进展 2024年第3期61卷 168-177页

作者： Chen fuguang Jiang Bofan Chen Zhi ma Siyuan Huang Yupeng Zhang Hang ma Zhijun Research Center for Humanoid Sensing Zhejiang LabHangzhou 311121ZhejiangChina State Key Laboratory of Luminescent materials and Devices School of Materials Science and EngineeringSouth China University of TechnologyGuangzhou 510641GuangdongChina Laboratory for Shock Wave and Detonation Physics Research Institute of Fluid PhysicsChina Academy of Engineering PhysicsMianyang 621900SichuanChina

Glass with heavy doping of noble metal nanoparticles is expected to exhibit high optical *** this study,the effects of glass composition,structure,and heat treatment on the formation of silver nanoparticles(Ag NPs)in phosphate-bismuthate(PB)glass are *** optimizing the chemical composition and preparation parameters,strong localized surface plasmon resonance is achieved in the PB glass with a silver mass fraction of more than 13%,which is 20 and 6 times higher than that in bismuthate and phosphate glasses reported previously,*** high solubility of the phosphate component and the self-reduction effect of the bismuthate component jointly contributed to the stability and high content of Ag NPs in the PB glass.Z-scan measurements show that such heavy doping PB glass has a reverse saturable absorption coefficient of-14×10^(-12)m·W^(-1)and a saturable absorption coefficient of 4.94×10^(-12)m·W^(-1)at 800 ***,the heavy doping PB glass exhibits excellent thermal stability,making it promising for the fabrication of nonlinear optical *** addition,with a heavily silver-doped PB glass rod as the core and a commercial silicate glass tube as the cladding,a composite glass fiber with high Ag-NP doping is successfully fabricated using a“molten-core”fiber drawing method.

关键词： phosphate-bismuthate glass silver nanoparticle optical nonlinearity molten-core fiber drawing

Extraction,chemical components,bioactive functions and adulteration identification of walnut oils:A review

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Grain & Oil Science and Technology 2024年第1期7卷 30-41页

作者： Yuan Gao Jia Hu Xia Su Qi Li Caihong Su Yongling Li Gaiqin ma Siyu Zhang Xiuzhu Yu Engineering Research Center of Grain and Oil functionalized Processing College of Food Science and EngineeringNorthwest A&F UniversityShaanxi 712100China Animal Products and Animal Medicine feed Quality Inspection Center Hebei 050041China

Walnut oil is a functional wood oil known to researchers that may potentially be a large source of Chinese edible *** are various extraction methods for walnut oil,including traditional(pressing,solvent-and enzymeassisted extraction)and novel methods(microwave,ultrasound,supercritical CO_(2),subcritical and other extraction technologies).Walnut oil is rich in nutrients,including phytosterols,tocopherols,polyphenols,squalene and *** provides many health benefits,such as antioxidant,antitumor,anti-inflammatory,antidiabetic and lipid metabolism-related *** addition,the authentication of walnut oil has received much research *** present review provides detailed research on walnut oil extraction,composition,health benefits and adulteration identification *** path toward further walnut oil improvement in the context of the market value of walnut oil is also discussed.

关键词： Extraction technology Chemical composition Bioactive Authentication

基于薯蓣皂苷元催化合成N-甲基吲哚孕烯醇酮化合物及其抗肿瘤活性

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高等学校化学学报 2024年第4期45卷 54-61页

作者：董远马养民马思悦孙任伟中国轻工业轻化工助剂重点实验室陕西科技大学化学与化工学院西安710021

利用N-甲基吲哚对类固醇药物的前驱体16-脱氢孕烯醇酮乙酸酯(16-DPA)的D环C16位进行修饰,采用ZrCl_4-乙酸乙酯廉价催化体系,合成了16个3β-乙酰氧基-16α-3'-吲哚孕烯醇酮化合物和6个3β-羟基-16α-3'-吲哚孕烯醇酮衍生物.该方法具有收... 详细信息

利用N-甲基吲哚对类固醇药物的前驱体16-脱氢孕烯醇酮乙酸酯(16-DPA)的D环C16位进行修饰,采用ZrCl_4-乙酸乙酯廉价催化体系,合成了16个3β-乙酰氧基-16α-3'-吲哚孕烯醇酮化合物和6个3β-羟基-16α-3'-吲哚孕烯醇酮衍生物.该方法具有收率高、立体选择性好和底物适应性强等优点.通过噻唑蓝(MTT)比色法测试了22个化合物对三阴性乳腺癌细胞(MDA-MB-231)的抗肿瘤活性.初步测试结果表明, 3β-乙酰氧基-16α-3'-吲哚孕烯醇酮化合物6h和6i对MDA-MB-231癌细胞有较好的抑制活性,其半数抑制浓度(IC_(50))分别为18.07和23.22μmol/L;而化合物7a~7f均对MDA-MB-231癌细胞有较好的抑制活性,其中化合物7e的抗肿瘤活性最好,其IC_(50)为12.50μmol/L.目标化合物为药物筛选提供了一定的参考.

关键词： 16-脱氢孕烯醇酮乙酸酯孕烯醇酮 N-甲基吲哚抗肿瘤活性

Design of IoT-based Volatile Organic Compounds Monitoring System

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Journal of Electronic Research and Application 2024年第3期8卷 161-171页

作者： Bo Wang Minghao ma School of Mechanical and Electrical Engineering Shaanxi University of Science and TechnologyXi’an 710021Shaanxi ProvinceChina

Volatile organic compounds(VOC)gas detection devices based on semiconductor sensors have become a common method due to their low cost,simple principle,and small ***,with the continuous development of materials science,various new materials have been applied in the fabrication of gas sensors,but these new materials have more stringent requirements for operating temperature,which cannot be met by existing sensor modules on the ***,this paper proposes a temperature-adjustable sensor module and designs an environmental monitoring system based on the STM32f103RET6 *** system primarily utilizes multiple semiconductor gas sensors to monitor and record the concentrations of various harmful gases in different *** can also monitor real-time temperature,humidity,and latitude and longitude in the current environment,and upload the data to the Internet of Things via 4G *** system has the advantages of small size,portability,and low *** results show that the sensor module can achieve precise control of operating temperature to a certain extent,with an average temperature error of approximately 3%.The monitoring system demonstrates a certain level of accuracy in detecting target gases and can promptly upload the data to a cloud platform for storage and processing.A comparison with professional testing equipment shows that the sensitivity curves of each sensor exhibit *** study provides engineering and technical references for the application of VOC gas sensors.

关键词： Sensors IoT Environmental monitoring VOC sensor STM32f103RET6