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Performance Analysis of Magnetic Nanoparticles during Targeted Drug Delivery:Application of OHAM

Computer Modeling in Engineering & Sciences 2022年第2期130卷 723-749页

作者： Muhammad Zafar Muhammad Saif Ullah Tareq Manzoor muddassir ali Kashif Nazar Shaukat Iqbal HabibUllah Manzoor Rizwan Haider Woo Young Kim Institute of Energy and Environmental Engineering University of the PunjabQuaid-e-Azam CampusLahore54590Pakistan Energy Research Centre COMSATS University IslamabadLahore54000Pakistan Department of Energy Engineering Faculty of Mechanical and Aeronautical EngineeringUniversity of Engineering and TechnologyTaxila47080Pakistan Department of Mathematics COMSATS University IslamabadLahore54000Pakistan School of Systems and Technology University of Management Sciences and TechnologyLahore54770Pakistan Department of Electrical Electronics and TelecommunicationEngineeringUniversity of Engineering and TechnologyLahore(FSD Campus)Faisalabad38000Pakistan Department of Electronic Engineering Faculty of Applied Energy SystemJeju National UniversityJeju Special Self-Governing ProvinceJeju-si63243Korea

In recent years,the emergence of nanotechnology experienced incredible development in the field of medical *** the past decade,investigating the characteristics of nanoparticles during fluid flow has been one of the intriguing *** distribution and uniformity have emerged as substantial criteria in both medical and engineering *** effects of chemotherapy on healthy tissues are known to be a significant concern during cancer therapy.A novel treatment method of magnetic drug targeting(MDT)has emerged as a promising topical cancer treatment along with some attractive advantages of improving efficacy,fewer side effects,and reduce drug *** magnetic drug targeting,the appropriate movement of nanoparticles(magnetic)as carriers is essential for the therapeutic process in the blood clot removal,infection treatment,and tumor cell *** this study,we have numerically investigated the behavior of an unsteady blood flowinfused with magnetic nanoparticles during MDT under the influence of a uniform external magnetic field in a *** optimal homotopy asymptotic method(OHAM)is employed to compute the governing equation for unsteady electromagnetohydrodynamics *** influence of Hartmann number(Ha),particle mass parameter(G),particle concentration parameter(R),and electro-osmotic parameter(k)is investigated on the velocity of magnetic nanoparticles and blood *** obtained show that the electro-osmotic parameter,along with Hartmann’s number,dramatically affects the velocity of magnetic nanoparticles,blood flow velocity,and flow ***,results also reveal that at a higher Hartman number,homogeneity in nanoparticles distribution improved *** particle concentration andmass parameters effectively influence the capturing effect on nanoparticles in the blood flow using a micro-tube for magnetic drug ***,investigation also indicates that the OHAM analysis is efficient and quick to h

关键词： Hartmann number magnetic nanoparticles nonlinear analysis targeted drug delivery optimal homotopy asymptotic method(OHAM)

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Some challenges in progressive control of livestock originated zoonotic diseases in Pakistan-a pilot survey

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Asian Pacific Journal of Tropical Biomedicine 2014年第10期4卷 821-824页

作者： Furqan Awan Muhammad muddassir ali Umair Iqbal Irfan Khattak Muhammad Hassan Mushtaq Department of Epidemiology and Public Health University of Veterinary and Animal SciencesLahore-54000Pakistan Institute of Biochemistry and Biotechnology University of Veterinary and Animal SciencesLahore-54000Pakistan Artificial Insemination Section Dairy and Rural Development FoundationDairy Project PMU Office 6/B-3Gulberg ⅢLahore-54000Pakistan

Objective:To document the recent livestock related practices and possible unhygienic ways of pathogen *** of the potential risk factors for the spread of infection is important to design an evidence-based disease control ***:Rapid assessment method was adopted and a purposive sample of 60 dairy farmers were *** following factors were noted for contributing in primary and secondary transmission of zoonotic infections:(i) persons who come in close contact with animals and their secretions,(ii) management strategies of farm animals(sheds and environment),(iii) management practices adopted at farms,(iv) small scale farmers and rural livestock production systems,(v)milk collection ***:This research unveiled the certain routes of zoonotic disease *** management practices,precautionary measures and strategies were the pivotal risk ***:The study emphasizes the need to educate the poor livestock keepers.

关键词： Zoonosis Risk assessment Zoonosis Livestock Emerging infections

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